选择标记物的方法

专利名称：选择标记物的方法
背景技术：
本申请要求享有序列号为60/368,789的美国临时申请(申请日为2002年3月29日)的利益。
本发明涉及诊断标记物框架的选择。
目前一些单基因诊断标记物，例如her-2-neu已有应用。然而，采用一种特定的基因进行分子诊断通常是不易确诊疾病。因此，多标记物常常是需要的，包括在基于不同基因调节的试验的上述标记物的数量往往很大，甚至会有上百种基因。人们希望将这些标记物归组到框架中，以便用最少数量的必需标记物来获得最为可靠的结果。这特别适用于那些包含多步骤分析的试验，如核酸扩增试验。
发明概述本发明是一种选择诊断用途标记物的框架的方法，在本方法中定义了诊断参数，确定了这些参数之间的关系以便进行优化，上述的关系式在诊断应用中用以选择优化的标记物组。
在本发明的另一个方面中，所述的诊断参数包括，基因表达的相对程度值，在测定基因表达的相对程度值过程中的变化量，和在诊断参数和区别参数之间是一种均方差关系。
本发明还进一步提供了可以程序化执行所述创造性方法的设备和包含操作指导的产品。
发明详述本发明的方法可以与任何测定相关细胞的基因表达模式的方法、或基于蛋白质测定基因表达的方法结合使用。优选的建立基因表达分布图的方法包括，测定由那些编码蛋白质或多肽的DNA转录的RNA的量。这可以通过反转录PCR(RT-PCR)，竞争性PT-PCR，实时PT-PCR，差异显示RT-PCR，Northern杂交分析以及其它相关的实验来实现。当可能用单个PCR反应实施这些技术时，最好扩增来自mRNA的互补DNA(cDNA)或互补RNA(cRNA)并用微阵列对其分析。对本领域的技术人员来说大量不同的阵列构型及其生产方法是已知的，并且也在如下的美国专利中有描述5,445,934；5,532,128；5,556,752；5,242,974；5,384,261；5,405,783；5,412,087；5,424,186；5,429,807；5,436,327；5,472,672；5,527,681；5,529,756；5,545,531；5,554,501；5,561,071；5,571,639；5,593,839；5,599,695；5,624,711；5,658,734；和5,700,637；这些专利披露的技术在此引入作为参考。
微阵列技术允许同时检测数千基因的稳定状态的mRNA水平，因此它为检测非控制的细胞增殖效果，如启动、抑制或调节等提供了一个强有力的工具。现在两种微阵列技术正被广泛使用。第一种是cDNA阵列，第二种是寡核苷酸阵列。尽管这些芯片在构造上存在差异，但其下游数据的分析和输出实质上是相同的。这些分析的结果典型地是对由标记探针获得的信号强度的测定，所述的探针用于检测与阵列上已知位点的序列杂交的、来自样品的cDNA序列。典型地，所述的信号强度与cDNA的含量，或者说样本细胞中所表达的mRNA的量成比例。有许多这样的技术可以获得并且是有用的。优选的检测基因表达的方法可以在美国专利中找到，如Linsley等人的专利6,271002；Friend等人的专利6,218,122；Peck等人的专利6,218,114；Wang等人的专利6,004,755，其所公开的内容均在此引入作为参考。
基因表达水平的分析通过比较强度进行。最好是通过制备一种待测样品中基因表达强度相对于对照样品中基因表达强度的比值矩阵进行。例如，可以将疾病组织中基因表达的强度与相同类型正常组织中的表达强度进行比较(例如患病的结肠组织样本对正常的结肠组织样本)。这个表达强度的比值显示出被测样本和对照样本中基因表达的倍数变化。
调节基因是那些在非正常细胞中表现为上调或下调的差异表达基因。上调和下调是相对的术语，表示可检测到的相对于某种基线的基因表达的量的差异(超出检测系统的噪音影响)。在这种情况中，基线是正常细胞测得的基因表达。再使用同样的测量方法确定患病细胞中所关注的基因相对于基线水平是上调或下调。
优选的，上升或下降调节的水平是以杂交的微阵列探针测量强度的成倍变化来区别的。在本申请中1.5倍或更高倍数的差别就可用于确定上述差异。即当认为与在正常细胞中相比一个基因在患病细胞中差异表达时，患病细胞中的强度至少是超出正常细胞的1.5倍或低于正常细胞1.5倍。
还有几种可行的区别上调和下调的方法。例如，统计分析试验可用于在多组样本中发现最大显著差异的基因。Student’s T检验就是一个发现两组之间显著差异的有力的统计检验的例子。p值越小，不同组之间基因显示差异的证据就越有说服力。然而既然微阵列可以同时检测多个基因，那么就需要同时进行万次的统计检验。因此，就存在偶尔看到极小p值的可能，并利用Sidak校正以及作出随机化/排列实验进行调整。
T检验中p值小于.05就证明基因是差异显著的。更有说服力的证据是加入Sidak校正因子后p值小于.05。对于每组中的大量样品，经过随机化/排列检验后p值小于.05是差异显著的最有说服力的证据。
将基因分组以便于通过获得一组基因中一套基因的信息为诊断、预测或治疗等相关临床判断提供可靠的基础。这些套基因构成了本发明的框架(portfolios)。对于大多数诊断标记物来说，最好使用尽量少的标记物就足以充分作出一个正确的医学判断。这就避免了使用那些悬而未决需作进一步分析的治疗措施带来的延误，同时又避免了时间和资源的不合理使用。优选的优化框架是采用最少数量的标记物来作出诊断，同时满足尽可能使确实正确的条件，这些条件通常包括对灵敏性和特异性方面的要求。基于诊断方法所构建的微阵列中，框架的灵敏度反映在一个基因在疾病状态下相对于其在正常状态下所表现出的基因表达的成倍差异中。如果某一基因与它在其它状态下的表达出现很大倍数的差别时，那么这种基因差异表达的检测是灵敏的。灵敏性的另一方面是区别信号和噪音的能力，例如，在某一组的基因的表达可显示出足够的灵敏性以确定某种给定的疾病状态的同时，如果其中某一基因所产生的信号强度(例如，微阵列中的强度测量值)低于某一水平以致无法容易地与某给定状态(例如，在某临床实验室)中所产生的噪音区分，那么该基因应该从最优化框架中剔除。定义上述这些优化框架条的过程也是本发明方法的组成部分。
感兴趣的状态下的基因表达的信号的相关性统计分析可以反映出基因框架的特异性。如果观察到某组基因的差异表达产生了很大倍数的差别，但是在除我们所感兴趣的状态(例如，多种疾病状态)之外的多种状态下均有相同的表现，则该组基因的表达分布就是非特异性的。对数据的相关性或数据的一致性，例如标准差、相关系数等进行分析的统计学方法可应用于这种测定中。在考虑某一框架中所包含的某一组基因时，在基因表达的测量值中小的标准差与更大的特异性相关。那些具有相似表达方式的基因受相同的因子的共调节，从而使这些基因趋向相同的方向。如果某因子对于样本分类是充分非必要的，则在所有的标记物均与这一因子相关时，这些基因就不能正确地鉴该样本。多样化使得选择尽量少的标记物成为可能，然而仍覆盖了包含于数据组中的同样多的不同的优化表达分布图。
在本发明的方法中，筛选出了一组用于诊断的标记物基因。上述这些标记物基因的组就是“框架”。它们在诊断中的应用包括检测或确定疾病状态或病人的状况，确定患有某种疾病的病人感染某种疾病的可能性，确定患有某种疾病的病人病人是否适于治疗，确定患有某种疾病的病人病人的预后(或者其好转或者其恶化)，以及确定患有某种疾病的病人病人的治疗效果。例如，该方法可用于建立检测病人是否患结肠癌及其患结肠癌可能性的的框架，该框架也可用于判断病人适用细胞毒素类药物的可能性。
本发明方法所筛选出来的框架包含一定数量和种类的标记物，既能确保诊断结果的准确性和精确性，又能使得构成该框架的基因在数量上经济。本发明的方法可用于研制适用于任何伴有多基因表达的疾病、病情、病况的优化基因表达框架。本发明中所述的优化的框架是指一种能够用于分析病人状况的基因表达分布图(建立在实施该分析所需条件都满足的基础上)，并且符合预先确定的至少两个下述参数准确性、精确性、框架中所包含的基因数目。
最优选地，框架中的标记物是能表达mRNA的核酸序列(基因)。该标记物在健康人体内能正常表达，当病人体内有待诊断时，则会更高地或更低地表达。可选择的是，除非所要诊断的疾病发生，否则该标记物不表达。
那些在本发明中可以被用来比较以诊断疾病的标记物的属性、特征、指标或测量值都是本方法中所使用的诊断参数。基因表达水平的指标是最优选的诊断参数。如上所述，这样的指标包括从微阵列读取的强度测量值。也可能有其它的诊断参数，如与标记物甲基化水平相关的指标。
通过使用彼此相关的数学/统计学数值，可以确定诊断参数间的差异，优选的差异是基因表达指标的信号读数平均值及其方差，最优选的差异是不同组读数(例如，微阵列强度测量值)的信号比值的平均值，以及信号比值测量值的标准差。大量上述的数学/统计学数值均能被合理地应用，例如在给定的百分点处回归。
关于诊断参数间差异的关系可被应用于优化诊断标记物的选择。典型地，此关系的确定是通过使用了线性或者二次方程的算法。然而，试探法也可以被使用或者被用于补充输入输出数据的选择。最优选的关系是均方差关系，例如在Harry M.Markowitz的《框架选择中均方差的分析和资本市场》，Mean-VarianceAnalysis in Pportfolio Choice and Capital Markets(Frank J.Fabozzi Associates，NewHope，2000年，ISBN1-883249-75-9)书中描述了这种关系，该文在此一并作为参考被引用。在选择哪些股票作为金融投资框架时，最容易理解这种关系，以上就是发展和阐明这种关系的内容。
投资者期望可以从现有的大量股票中选择最优化的股票框架，但每支股票都有其以往的回报率和风险因素。均方差法采用了严格线性一次或二次方程算法来确定所有可能的框架，以及在一个给定的期待回报率的水平上使得风险水平最小化，以及在一个给定的风险水平上使得期待回报率最大化(如通过计算方差或标准差)。当计算出预期回报的标准差后，一个有效的边界就产生了，依据此有效边界来选择股票，就会根据股票回报和风险在不同的股票框架中选择优化的框架。
当均方差关系应用于本发明的方法中时，诊断参数如微阵列的信号强度和标准差就取代了在选择金融投资框架中所使用的回报和风险因素。最优选地，当使用均方差关系时，可以使用商业计算机软件如“Wagner联合均值-方差优化应用程序”，在整个说明书中称为“Wagner软件”的“Wagner联合均值-方差优化应用程序”是优选的。这个软件使用“Wagner联合均值-方差优化库”中的功能，来确定有效边界和Markowitz意义上优选的优化框架。由于上述功能是为金融方面的应用而设计的，因此必须将输入的数据进行预处理，使数据能够符合该软件的要求，例如，当Wagner软件应用在测定微阵列信号强度值时，要应用以下的数据转换方法。
首先要确定每个基因的基线与试验值之间的关系，优选的过程如下所述。首先通过确定那些其表达至少显示出某种微小差异水平的基因，对基因进行预选择。优选的预选择过程如下所述。选择一个基线组。典型的基线组包含来自未患有所述疾病的群体的基因。例如，在选择所用于诊断乳腺癌的框架时，可以将未患乳腺癌患者的样本用作制备基线组。一旦选择了基线组，就可以计算出基线组样本中每个基因的表达指标的算术平均值和标准差。典型的，这个指标是微阵列记录的荧光强度。随后将通过计算得到的统计学数据用于计算每个基因的基线值(X*标准差+均值)。这就是基因的基线记录，其它所有样本都要与其相比较。X是由制定框架的人选择出来的严格变量。X的数值越大就越严格。优选的X数值范围是0.5-3，更优选的是2-3，最优选的是3。
随后计算每个实验样本(那些所关注的样本)与基线记录的比值。再将这些比值转换成易于软件处理的底数为10的对数值。该方法使下调基因显示为使用Wagner软件并按照Markman均值-方差算法所必需优化的负值。
将包含这些转换比值的预处理数据作为输入替代用于金融分析目的的Wagner软件中通常使用的资产回报值。
一旦制定出有效边界，对于一个给定的输入水平值(返回值)或对应于边界上的一个点的方差，就可以选择出一个优化框架。这些输入值或方差是制定框架的人预先确定的标准数集。换句话说，寻求最适框架的人决定一个可接受的输入水平(表明灵敏度)或者一个给定的方差水平(表明特异性)，选择位于该输入水平或方差相应的有效边界选择基因。当选定了输入水平或方差，Wagner软件就能够选择出这样的基因。Wagner软件可以像对股票笼统投资中每支股票所做的那样，分配所述框架中每个基因的分量。
将患者样本框架中的基因中的表达，与用于构建所述框架的差异表达基因的计算值相比较，就可以确定该样本是否患有该框架所诊断的疾病。优选的，首先通过将在选择框架的过程中给每个基因分配的权重乘以框架中每个基因的强度值，加和得到框架值。然后用(Y*标准差+基线组中框架的均值)计算临界值，其中Y是一个严格数值，具有与上述X相同的含义。一个样本具有的框架值大于基线组的框架值，则此样本就被归为患病类。需要时，可以根据已知的统计学方法重复上述过程提高可信度水平。
任选的，可以重复进行上述过程直到获得预期的最高准确度。
框架选择的过程和未知量的表征过程概括如下1.选择基线组2.计算基线组样本中每个基因的均值和标准差3.计算每个基因的(X*标准差+均值)。这就是基线记录，其它所有的样本都要与这个基线记录相比较。X是一严格变量，X数值越大就越严格。
4.计算根据步骤3得到的每个实验样本对基线记录的比值。
5.转换数值，使值小于1的比值成为负数(例如使用底数为10的对数)。(现在下调的基因有正确的负值以符合MV优化的需要)。
6.将这些转换的比值作为输入值，替换软件应用中通常使用的资产回报值。
7.该软件将标绘出有效的边界线，并且返回一组沿此有效边界线上任意一点的优化框架。
8.在此有效边界线上选择一个所需的返回值或者方差9.通过将在选择框架的算法中所给定的权重乘以每个基因的强度值，加和计算每个样本的框架值。
10.将基线组的框架值的均值加上Y与基线组的框架值的标准差的乘积，计算出临界值。大于该临界值的数值应被归为实验组。
11.任选的，可以重复进行上述过程，直到获得预期的最佳准确度。
任选地，通过颠倒基线和实验值的计算可以创建第二框架。这创建一个对于最初的基线而言是上调的基因的新框架。第一框架值减去第二框架值就创建了一个基于多框架新的分类值。
另一个有用的从基因表达数据中预选择基因，使其用作选择框架的输入的方法，以1≤|(μi-μn)(σi+σn)|]]>给出的阈值为基础，其中μt是已知患病或有该疾病的样本子集的均值，μn是正常样本子集的均值，σt+σn表示联合标准差。通过对根据0.5≤|(μt-MAXn)(σt+σn)|]]>得到的数据的预选择，噪音中止点的信号也能在其中使用。这就确保基于差异调节进行预选择的基因具有临床上的显著差异。即超过了适于测定各种临床参数的仪器产生的噪音水平。对于根据这些标准预选的每个标记物建立一个矩阵，其中列表示样本，行表示标记物，并且每个元件都是根据|(μt-I)μt|]]>对该标记物的表达进行标准化后所得到的强度测量值，其中I代表强度测量值。为金融组合软件产生输入值的方法，也可以允许设定附加的临界条件，以此来定义优化框架。例如，框架的大小可限定为固定的值域或标记物的数目。这或者可以通过制定更为严格的预选标准(例如以0.8≤|(μt-MAXn)(σt+σn)|]]>代替0.5≤|(μt-MAXn)(σt+σn)|]]>)或通过使用程序特征如限制组合大小来实现。例如可以设置边界条件使有效边界线从最优化的10个基因中选出。也可以使用所有的预选基因确定有效边界线后再限定选择基因的数目(例如不超过10个)。
选择框架的过程也包括应用探索式的规则。优选的，这样的规则是基于生物学和对用于产生临床结果的技术理解的基础上制定的。更优选的是，它们应用到优选方法的输出数据中。例如，选择框架的均方差法可以应用于乳腺癌样本中大量差异表达基因的微阵列数据。这种方法得到的输出数据将会是一套优选的基因，包括既在外周血中表达也在患病乳腺组织中表达的一些基因。如果这种检测方法用到的样本来自外周血，并且某些基因既在乳腺癌个例也在外周血中差异表达，那么就可以应用探索式的规则，从排除了那些在外周血中差异表达的基因而得到的有效边界线上选择框架。当然，这个规则可以在形成有效边界线前应用，例如，将该规则应用到数据的预先选择中。
可以应用其他与未有定论的生物学问题无必然联系的探索式规则。例如，可以应用只有给定百分比的框架可用特定的基因表示的规则。商业上可购买的软件如Wagner软件就提供了这类型的探索式规则。这是非常有用的，例如，除了正确度和精密度(例如，预支专利转让费)等，其他因素也会影响包括一个或多个基因的可用性。
除了均方差关系式外的其它关系式也可以依据预先测定的贡献值如试验的准确度和精确性而用于本发明所提供的方法来优化框架。这里有两个例子，分别是Martin联立方程法(Elton，Edwin J.and Martin J.Gruber(1987)，ModernPortfolio Theory Investment Analysis，Third Edition，Johun Wiley，New York，1987)和遗传算法(Davis，L.，(1989)，Adapting Operator Probabilities in GeneticAlgorithms，in Proceedings of the Third International Conference on GeneticAlgorithms，Morgan KaufnannSan Mateo，pp.61-69)。还有更多的适用均方差关系式的方法可用来处理不均匀的数据如在标记物检测技术中存在着明显偏差的数据，包括半偏差法，所述的半偏差法中那些相对于基准信号的偏差值(负数)，即仅低于基准值的信号值，首先被平方，然后再平均，最后再开方。
本发明的制品包括用于治疗、诊断、预测和其它疾病评估的基因表达分布图的表示物。这些分布图表示物简化为可被机器自动可读的媒介物，如计算机可读媒介(磁性的，光学的及类似的)。制品也包括在这种媒介中评估基因表达分布图的指令说明。例如，制品可能包括具有用于比较上述基因组合的基因表达分布图的计算机指令的CD ROM。制品可能也含有基因表达分布图的数字记录以用于与病例样本的基因表达数据进行比较。可选择的，所述的分布图可以不同的表现格式记录。
根据本发明生产制造的不同类型的物品是指用于揭示基因表达分布图的媒介物或格式化检测。这些可以包括，例如微阵列，其中将序列互补物或探针固定于基片上，它与表示所关注基因的序列联合建立一个易读行列式。通过最小化应用于底物、与样本反应，通过分析器读取信号，进而产生结果，和(有时)进行校验的cDNA或寡核苷酸的数目获得的这样一个可以大大节约时间、步骤和资源的包括优化框架的微阵列。
本发明的其他产品可被制成试剂盒，用于杂交、扩增和产生信号，依此来指示依据本发明的方法所确立的框架中基因的表达水平。根据本发明制备的试剂盒包括确定基因表达分布图的格式化检测。这就包括了进行检测所需的如试剂和说明指令等所有或部分材料。
实施例实施例1优化框架的产生最近，从有代表性的11种不同类型癌症的组织样本中获得了基因表达数据。这些数据发表在“Cancer Research，2000，61，7388-7393和http//carrier.gnf.org/welsh/epican/。见Andrew I.Su等，题目是“MolecularClassification of Human Carcinomas by Use of Gene Expression Signatures”。这些数据包括使用“U95”的寡聚核苷酸微阵列(可以从Affymetrix公司商业购买)所得到得的信号测量强度值。
目前公开的基因表达的测量法(荧光强度测量法)可以用来为标记物平板选择最适的基因表达框架，用以检测循环细胞中是否有指示乳腺癌，前列腺癌，卵巢癌，结肠直肠癌，或者肺癌存在的信号，这种循环细胞优选是上皮细胞。
本研究所用的数据来自下列样本24例腺癌，12例浸润导管型乳腺腺癌，21例结肠直肠腺癌，23例卵巢腺癌，25例肺癌，以及来自从如下的另外的样本19例前列腺腺癌，12例乳腺癌，13例结肠癌，13例卵巢癌和89例肺癌。
将一组正常样本中所得到的强度测量值作为基线族，先计算出基线族中每一个基因的值(X*标准差+平均值)，以此算出它们的算术平均值以及每个基因的标准差。在本实施例中，严格变量X赋值为3，接着计算每个待测样本值与基线值的比值，然后将该比值转化为常用对数值，接下来，把得到的对数值输入到Wagner软件。
选择一个对于每一类型的肿瘤具有最少数量标记物的有效边界，该边界对于一个选定的差异水平具有最小的方差(在信噪比最佳的点选择)。通过软件的最优化作用，选择了一个具有24个基因的框架，所述的基因中，2种针对于检测前列腺癌，5种针对于检测乳腺癌，6种针对于检测结肠癌，2种针对于检测卵巢癌，9种针对于检测肺癌的标记物(见表1)。
表1
实施例2试探步骤一个试探规则可以进一步应用于从实施例1中所得到的框架。这个规则是这样的，如果要测定的基因/标记物可能在外周血中表达或者是易鉴定的组织标记物(如PSA，哺乳动物球蛋白等等)，那么这些基因/标记物将被从框架中剔除。应用此规则可以确定优化的基因/标记物框架，此框架可以应用于筛选从检测来源于外周血的混合物如上皮细胞而得到的患者样本。包含了31个基因的被选择的框架的结果见表2。
表2
实施例3用于疾病预后诊断的框架用一个已知临床结果的病人样本组来检验本发明的框架选择方法。在van’tVeer，L.J et al.Genen Expression Profiling Predicts Clinical Outcome of BreastCaner，Nature，415，530-536，(2002)中公开了这个样本组，该文在此引入作为参考。在van’t Veer，L.J的研究中，乳腺组织样品是来自78位患有散发性乳腺肿瘤的病人。所有这些病人的年龄都小于55岁，并且所患的肿瘤小于5厘米。所有病人的淋巴结都没有肿大。有34位病人在5年内有肿瘤的远处转移，44位患者同一时期没有发生远处转移。
将来自上述研究的数据根据本发明的方法进一步处理。54号样本在进一步的分析中发现有高漏诊率，因而被排除。将没有发生肿瘤转移的样本作为基线，计算每一个基因信号强度值的均值和标准差，接着计算每一个基线基因的差异值X*(标准差+均值)(X赋值为3)，这个值用来确保最终得到的框架的严格性。计算每一个有肿瘤转移的样本差异值与基线值的比值，将这个比值转换为常用对数，然后将对数值输入到Wagner软件中得到一个有效边界并随之产生一个由16个基因构成的框架。将基线值和试验值颠倒过来计算比值，得到由12种代表在非转移病例中上调基因的标记物所组成的框架，第一种框架的值减去第二种框架的值，得到从所有28个基因组成的联合框架的值。最终的框架由序列No.70-97的基因组成，这个框架中有17种基因也在参考文献中的70个基因框架中被描述过。对框架中的基因鉴定如下。(基因序列号No.70，No.72，No.73-77，No.79，No.80，No.85，No.87，No.91-93，No.95和No.97)
28个基因列表(2个框架)上述在转移病人中的基因(框架1)
17个与文献中重复的基因
这两个框架按照参考文献中记载的测试分类的精确度的方法比较从微阵列数据中得到的基因表达信号，来确定78例原始样本的预后。在包含有70个基因的框架中，根据最优化的阈值，81％的样本能够被正确地判断，其它偏离该最优化阈值的样本具有模棱两可的信号值，被指示为不良的预后(85％的绝对阈值)。此框架由于使用了最优化的阈值，使3例预后不良的病人被错误地归为预后良好(采用绝对阈值时为5例)，12例预后良好的病人当它们使用优化的阈值判断时具有预后不良，而被错误的归为预后良好(采用绝对阈值时为8例)。
在包含有28个基因的框架中，根据优化的阈值，94％的样本能够被正确地判断，其它偏离该最优化阈值的样本具有模棱两可的信号值，被指示为不良的预后(93％的绝对阈值)。此框架由于使用了优化的阈值，使3例预后不良的病人被错误地归为预后良好(采用绝对阈值时为5例)，3例预后良好的病人当它们使用优化的阈值判断时具有预后不良，而被错误的归为预后良好(采用绝对阈值时为2例)。
通过比较上述两个框架可以很明显地发现，根据本发明的方法所选择的框架比其它的框架更经济，得到的结果更精确和更可靠。
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cagaaataaa gagctgttat actgtg1466<210>2<211>785<212>DNA<213>人<400>2atgtgggacc tggttctctc catcgccttg tctgtggggt gcactggtgc cgtgcccctc 60atccagtctc ggattgtggg aggctgggag tgtgagaagc attcccaacc ctggcaggtg120gctgtgtaca gtcatggatg ggcacactgt gggggtgtcc tggtgcaccc ccagtgggtg180ctcacagctg cccattgcct aaagaagaat agccaggtct ggctgggtcg gcacaacctg240tttgagcctg aagacacagg ccagagggtc cctgtcagcc acagcttccc acacccgctc300tacaatatga gccttctgaa gcatcaaagc cttagaccag atgaagactc cagccatgac360ctcatgctgc tccgcctgtc agagcctgcc aagatcacag tgttgtgaag gtcctgggcc420tgcccaccca ggagccagca ctggggacca cctgctacgc ctcaggctgg ggcagcatcg480aaccagagga gttcttgcgc cccaggagtc ttcagtgtgt gagcctccat ctcctgtcca540atgacatgtg tgctagagct tactctgaga aggtgacaga gttcatgttg tgtgctgggc600tctggacagg tggtaaagac acttgtgggg gtgattctgg gggtccactt gtctgtaatg660gggtgcttca aggtatcaca tcatggggcc ctgagccatg tgccctgcct gaaaagcctg720ctgtgtacac caaggtggtg cattaccgga agtggatcaa ggacaccatc gcagccaacc780cctga785<210>3<211>503<212>DNA<213>人<400>3gacagcggct tccttgatcc ttgccacccg cgactgaaca ccgacagcag cagcctcacc 60atgaagttgc tgatggtcct catgctggcg gccctctccc agcactgcta cgcaggctct120ggctgcccct tattggagaa tgtgatttcc aagacaatca atccacaagt gtctaagact180gaatacaaag aacttcttca agagttcata gacgacaatg ccactacaaa tgccatagat240gaattgaagg aatgttttct taaccaaacg gatgaaactc tgagcaatgt tgaggtgttt300atgcaattaa tatatgacag cagtctttgt gatttatttt aactttctgc aagacctttg360gctcacagaa ctgcagggta tggtgagaaa ccaactacgg attgctgcaa accacacctt420ctctttctta tgtcttttta ctacaaacta caagacaatt gttgaaacct gctatacatg480tttattttaa taaattgatg gca503<210>4<211>2560<212>DNA<213>人<400>4
gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct1020ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat1080caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc1140cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc1200ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta1260tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat1320ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag1380cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac1440agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg1500cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa1560tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca1620gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa1680caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg1740tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat1800ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc1860aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct1920gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac1980atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca2040gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt2100
aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc2160aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt2220aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac2280agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca2340tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag2400cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg2460atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag2520ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560<210>5<211>2560<212>DNA<213>人<400>5gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc120caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct180tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc240ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg300ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc360atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca420ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg480ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca540gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt600gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca660gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg720caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc780catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa840ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct900gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt960cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct 1020ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat 1080caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc 1140cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc 1200ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta 1260tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat 1320ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag 1380
cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac1440agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg1500cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa1560tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca1620gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa1680caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg1740tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat1800ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc1860aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct1920gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac1980atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca2040gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt2100aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc2160aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt2220aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac2280agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca2340tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag2400cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg2460atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag2520ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560<210>6<211>2439<212>DNA<213>人<400>6cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660
cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg1020gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg1080gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga1140cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa1200ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca1260gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag1320cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc1380taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga1440cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca1500ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa1560ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag1620ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt1680ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt1740gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac1800ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt1860catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga1920gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa1980cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg2040aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt2100gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt2160cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat2220catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca2280tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc2340gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag2400aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439<210>7<211>2439<212>DNA<213>人<400>7cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac60
cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg1020gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg1080gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga1140cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa1200ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca1260gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag1320cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc1380taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga1440cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca1500ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa1560ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag1620ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt1680ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt1740gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac1800ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt1860catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga1920gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa1980cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg2040aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt2100
gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt2160cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat2220catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca2280tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc2340gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag2400aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439<210>8<211>1699<212>DNA<213>人<400>8aggtgagcgg ttgctcgtcg tcggggcggc cggcagcggc ggctccaggg cccagcatgc 60gcgggggacc ccgcggccac catgtatgtg ggctatgtgc tggacaagga ttcgcccgtg 120taccccggcc cagccaggcc agccagcctc ggcctgggcc cggcaaacta cggccccccg 180gccccgcccc cggcgccccc gcagtacccc gacttctcca gctactctca cgtggagccg 240gcccccgcgc ccccgacggc ctggggggcg cccttccctg cgcccaagga cgactgggcc 300gccgcctacg gcccgggccc cgcggcccct gccgccagcc cagcttcgct ggcattcggg 360ccccctccag actttagccc ggtgccggcg ccccctgggc ccggcccggg cctcctggcg 420cagcccctcg ggggcccggg cacaccgtcc tcgcccggag cgcagaggcc gacgccctac 480gagtggatgc ggcgcagcgt ggcggccgga ggcggcggtg gcagcggtaa gactcggacc 540aaggacaagt accgcgtggt ctacaccgac caccaacgcc tggagctgga gaaggagttt 600cattacagcc gttacatcac aatccggcgg aaatcagagc tggctgccaa tctggggctc 660actgaacggc aggtgaagat ctggttccaa aaccggcggg caaaggagcg caaagtgaac 720aagaagaaac agcagcagca acagccccca cagccgccga tggcccacga catcacggcc 780accccagccg ggccatccct ggggggcctg tgtcccagca acaccagcct cctggccacc 840tcctctccaa tgcctgtgaa agaggagttt ctgccatagc cccatgccca gcctgtgcgc 900cgggggacct ggggactcgg gtgctgggag tgtggctcct gtgggcccag gaggtctggt 960ccgagtctca gccctgacct tctgggacat ggtggacagt cacctatcca ccctctgcat1020ccccttggcc cattgtgtgc agtaagcctg ttggataaag accttccagc tcctgtgttc1080tagacctctg ggggataagg gagtccaggg tggatgatct caatctcccg tgggcatctc1140aagccccaaa tggttggggg aggggcctag acaaggctcc aggccccacc tcctcctcca1200tacgttcaga ggtgcagctg gaggcctgtg tggggaccac actgatcctg gagaaaaggg1260atggagctga aaaagatgga atgcttgcag agcatgacct gaggagggag gaacgtggtc1320aactcacacc tgcctcttct gcagcctcac ctctacctgc ccccatcata agggcactga1380gcccttccca ggctggatac taagcacaaa gcccatagca ctgggctctg atggctgctc1440cactgggtta cagaatcaca gccctcatga tcattctcag tgagggctct ggattgagag1500
ggaggccctg ggaggagaga agggggcaga gtcttcccta ccaggtttct acacccccgc 1560caggctgccc atcagggccc agggagcccc cagaggactt tattcggacc aagcagagct 1620cacagctgga caggtgttgt atatagagtg gaatctcttg gatgcagctt caagaataaa 1680tttttcttct cttttcaaa1699<210>9<211>4098<212>DNA<213>人<400>9ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg1020gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca1080ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga1140tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat1200ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg1260gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg1320gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa1380tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag1440ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta1500ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt1560ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga1620
ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa1680atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca1740ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc1800gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg1860cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc1920taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag1980gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat2040ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg2100ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca2160tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat2220atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc2280ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag2340taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt2400atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga2460cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa2520actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc2580atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg2640gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc2700ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag2760gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc2820ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact2880tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc2940tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg3000gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca3060aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa3120ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc3180aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg3240tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca3300agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag3360accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata3420tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg3480aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa3540tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga3600cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta3660ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat3720
ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga3780gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact3840tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat3900ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg3960ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc4020ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa4080agcgtgttaa ctttttgg 4098<210>10<211>4098<212>DNA<213>人<400>10ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg1020gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca1080ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga1140tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat1200ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg1260gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg1320gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa1380tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag1440
ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta1500ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt1560ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga1620ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa1680atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca1740ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc1800gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg1860cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc1920taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag1980gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat2040ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg2100ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca2160tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat2220atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc2280ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag2340taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt2400atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga2460cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa2520actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc2580atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg2640gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc2700ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag2760gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc2820ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact2880tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc2940tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg3000gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca3060aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa3120ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc3180aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg3240tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca3300agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag3360accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata3420tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg3480
aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa3540tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga3600cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta3660ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat3720ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga3780gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact3840tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat3900ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg3960ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc4020ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa4080agcgtgttaa ctttttgg 4098<210>11<211>3311<212>DNA<213>人<400>11tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt1020gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt1080gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa1140aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag1200
aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga1260caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc1320aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg1380gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac1440agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg1500tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat1560ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac1620gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa1680gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt1740cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct1800cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat1860ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca1920acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta1980gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact2040tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg2100tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa2160ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg2220gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg2280gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca2340acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca2400gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag2460aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac2520aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca2580aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt2640cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga2700acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc2760aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa2820gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct2880attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct2940ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct3000tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg3060aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata3120aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc3180tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg3240ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac3300
aactgggtaa a 3311<210>12<211>3311<212>DNA<213>人<400>12tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt1020gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt1080gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa1140aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag1200aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga1260caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc1320aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg1380gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac1440agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg1500tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat1560ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac1620gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa1680gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt1740cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct1800
cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat1860ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca1920acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta1980gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact2040tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg2100tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa2160ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg2220gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg2280gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca2340acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca2400gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag2460aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac2520aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca2580aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt2640cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga2700acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc2760aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa2820gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct2880attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct2940ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct3000tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg3060aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata3120aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc3180tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg3240ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac3300aactgggtaa a 3311<210>13<211>15720<212>DNA<213>人<400>13caacccacac cgcccctgcc agccaccatg gggctgccac tagcccgcct ggcggctgtg 60tgcctggccc tgtctttggc agggggctcg gagctccaga cagagggcag aacccgatac120cacggccgca acgtctgcag cacctggggc aacttccact acaagacctt cgacggggac180gtcttccgct tccccggcct ctgcgactac aacttcgcct ccgactgccg aggctcctac240aaggaatttg ctgtgcacct gaagcggggt ccgggccagg ctgaggcccc cgccggggtg300
gagtccatcc tgctgaccat caaggatgac accatctacc tcacccgcca cctggctgtg 360cttaacgggg ccgtggtcag caccccgcac tacagccccg ggctgctcat tgagaagagc 420gatgcctaca ccaaagtcta ctcccgcgcc ggcctcaccc tcatgtggaa ccgggaggat 480gcactcatgc tggagctgga cactaagttc cggaaccaca cctgtggcct ctgcggggac 540tacaacggcc tgcagagcta ttcagaattc ctctctgacg gcgtgctctt cagtcccctg 600gagtttggga acatgcagaa gatcaaccag cccgatgtgg tgtgtgagga tcccgaggag 660gaggtggccc ccgcatcctg ctccgagcac cgcgccgagt gtgagaggct gctgaccgcc 720gaggccttcg cggactgtca ggacctggtg ccgctggagc cgtatctgcg cgcctgccag 780caggaccgct gccggtgccc gggcggtgac acctgcgtct gcagcaccgt ggccgagttc 840tcccgccagt gctcccacgc cggcggccgg cccgggaact ggaggaccgc cacgctctgc 900cccaagacct gccccgggaa cctggtgtac ctggagagcg gctcgccctg catggacacc 960tgctcacacc tggaggtgag cagcctgtgc gaggagcacc gcatggacgg ctgtttctgc1020ccagaaggca ccgtatatga cgacatcggg gacagtggct gcgttcctgt gagccagtgc1080cactgcaggc tgcacggaca cctgtacaca ccgggccagg agatcaccaa tgactgcgag1140cagtgtgtct gtaacgctgg ccgctgggtg tgcaaagacc tgccctgccc cggcacctgt1200gccctggaag gcggctccca catcaccacc ttcgatggga agacgtacac cttccacggg1260gactgctact atgtcctggc caagggtgac cacaacgatt cctacgctct cctgggcgag1320ctggccccct gtggctccac agacaagcag acctgcctga agacggtggt gctgctggct1380gacaagaaga agaatgcggt ggtcttcaag tccgatggca gtgtactgct caaccagctg1440caggtgaacc tgccccacgt gaccgcgagc ttctctgtct tccgcccgtc ttcctaccac1500atcatggtga gcatggccat tggcgtccgg ctgcaggtgc agctggcccc agtcatgcaa1560ctctttgtga cactggacca ggcctcccag gggcaggtgc agggcctctg cgggaacttc1620aacggcctgg aaggtgacga cttcaagacg gccagcgggc tggtggaggc cacgggggcc1680ggctttgcca acacctggaa ggcacagtca acctgccatg acaagctgga ctggttggac1740gatccctgct ccctgaacat cgagagcgcc aactacgccg agcactggtg ctccctcctg1800aagaagacag agaccccctt tggcaggtgc cactcggctg tggaccctgc tgagtattac1860aagaggtgca aatatgacac gtgtaactgt cagaacaatg aggactgcct gtgcgccgcc1920ctgtcctcct acgcgcgcgc ctgcaccgcc aagggcgtca tgctgtgggg ctggcgggag1980catgtctgca acaaggatgt gggctcctgc cccaactcgc aggtcttcct gtacaacctg2040accacctgcc agcagacctg ccgctccctc tccgaggccg acagccactg tctcgagggc2100tttgcgcctg tggacggctg cggctgccct gaccacacct tcctggacga gaagggccgc2160tgcgtacccc tggccaagtg ctcctgttac caccgcggtc tctacctgga ggcgggggat2220gtggtcgtca ggcaggaaga acgatgtgtg tgccgggatg ggcggctgca ctgtaggcag2280atccggctga tcggccagag ctgcacggcc ccaaagatcc acatggactg cagcaacctg2340
actgcactgg ccacctcgaa gccccgagcc ctcagctgcc agacgctggc cgccggctat2400taccacacag agtgtgtcag tggctgtgtg tgccccgacg ggctgatgga tgacggccgg2460ggtggctgcg tggtggagaa ggaatgccct tgcgtccata acaacgacct gtattcttcc2520ggcgccaaga tcaaggtgga ctgcaatacc tgcacctgca agagaggacg ctgggtgtgc2580acccaggctg tgtgccatgg cacctgctcc atttacggga gtggccacta catcaccttt2640gatgggaagt actacgactt tgacggacac tgctcctacg tggctgttca ggactactgc2700ggccagaact cctcactggg ctcattcagc atcatcaccg agaacgtccc ctgtggcact2760acgggcgtca cctgctccaa ggccatcaag atcttcatgg ggaggacgga gctgaagttg2820gaagacaagc accgtgtggt gatccagcgt gatgagggtc accacgtggc ctacaccacg2880cgggaggtgg gccagtacct ggtggtggag tccagcacgg gcatcatcgt catctgggac2940aagaggacca ccgtgttcat caagctggct ccctcctaca agggcaccgt gtgtggcctg3000tgtgggaact ttgaccaccg ctccaacaac gacttcacca cgcgggacca catggtggtg3060agcagcgagc tggacttcgg gaacagctgg aaggaggccc ccacctgccc agatgtgagc3120accaaccccg agccctgcag cctgaacccg caccgccgct cctgggccga gaagcagtgc3180agcatcctca aaagcagcgt gttcagcatc tgccacagca aggtggaccc caagcccttc3240tacgaggcct gtgtgcacga ctcgtgctcc tgtgacacgg gtggggactg tgagtgcttc3300tgctctgccg tggcctccta cgcccaggag tgtaccaaag agggggcctg cgtgttctgg3360aggacgccgg acctgtgccc catattctgc gactactaca accctccgca tgagtgtgag3420tggcactatg agccatgtgg gaaccggagc ttcgagacct gcaggaccat caacggcatc3480cactccaaca tctccgtgtc ctacctggag ggctgctacc cccggtgccc caaggacagg3540cccatctatg aggaggatct gaagaagtgt gtcactgcag acaagtgtgg ctgctatgtc3600gaggacaccc actacccacc tggagcatcg gttcccaccg aggagacctg caagtcctgc3660gtgtgtacca actcctccca agtcgtctgc aggccggagg aaggaaagat tcttaaccag3720acccaggatg gcgccttctg ctactgggag atctgtggcc ccaacgggac ggtggagaag3780cacttcaaca tctgttccat tacgacacgc ccgtccaccc tgaccacctt caccaccatc3840accctcccca ccacccccac ctccttcacc actaccacca ccaccaccac cccgacctcc3900agcacagttt tatcaacaac tccgaagctg tgctgcctct ggtctgactg gatcaatgag3960gaccacccca gcagtggcag cgacgacggt gaccgagaac catttgatgg ggtctgcggg4020gcccctgagg acatcgagtg caggtcggtc aaggatcccc acctcagctt ggagcagcat4080ggccagaagg tgcagtgtga tgtctctgtt gggttcattt gcaagaatga agaccagttt4140ggaaatggac catttggact gtgttacgac tacaagatac gtgtcaattg ttgctggccc4200atggataagt gtatcaccac tcccagccct ccaactacca ctcccagccc tccaccaacc4260acgacgacca cccttccacc aaccaccacc cccagccctc caaccaccac cacaaccacc4320cctccaccaa ccaccacccc cagccctcca ataaccacca cgaccacccc tctaccaacc4380accactccca gccctccaat aagcaccaca accacccctc caccaaccac cactcccagc4440
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acggagtcaa ccacccttct gagtacccta ccacctgcca ttgagatgac cagcacggcc 12780ccaccctcca cacccacggc acccacgacc acgagcggag gccacacact gtctccaccg 12840cccagcacca ccacgtcccc tccaggcacc cccactcgcg gtaccacgac cgggtcatct 12900tcagccccca cccccagcac tgtgcagacg accaccacca gtgcctggac cccaacgccg 12960accccactct ccacacccag catcatcagg accacaggcc tgaggcccta cccttcctct 13020gtgcttatct gctgtgtcct gaacgacacc tactacgcac caggtgagga ggtgtacaac 13080ggcacatacg gagacacctg ttatttcgtc aactgctcac tgagctgtac gttggagttc 13140tataactggt cctgcccatc cacgccctcc ccaacaccca cgccctccaa gtcgacgccc 13200acgccttcca agccatcgtc cacgccctcc aagccgacgc ccggcaccaa gccccccgag 13260tgcccagact ttgatcctcc cagacaggag aacgagactt ggtggctgtg cgactgcttc 13320atggccacgt gcaagtacaa caacacggtg gagatcgtga aggtggagtg tgagccgccg 13380cccatgccca cctgctccaa cggcctccaa cccgtgcgcg tcgaggaccc cgacggctgc 13440tgctggcact gggagtgcga ctgctactgc acgggctggg gcgacccgca ctatgtcacc 13500ttcgacggac tctactacag ctaccagggc aactgcacct acgtgctggt ggaggagatc 13560agcccctccg tggacaactt cggagtttac atcgacaact accactgcga tcccaacgac 13620aaggtgtcct gtccccgcac cctcatcgtg cgccacgaga cccaggaggt gctgatcaag 13680accgtgcata tgatgcccat gcaggtgcag gtgcaggtga acaggcaggc ggtggcactg 13740ccctacaaga agtacgggct ggaggtgtac cagtctggca tcaactacgt ggtggacatc 13800cccgagctgg gtgtcctcgt ctcctacaat ggcctgtcct tctccgtcag gctgccctac 13860caccggtttg gcaacaacac caagggccag tgtggcacct gcaccaacac cacctccgac 13920gactgcattc tgcccagcgg ggagatcgtc tccaactgtg aggctgcggc tgaccagtgg 13980ctggtgaacg acccctccaa gccacactgc ccccacagca gctccacgac caagcgcccg 14040gccgtcactg tgcccggggg cggtaaaacg accccacaca aggactgcac cccatctccc 14100ctctgccagc tcatcaagga cagcctgttt gcccagtgcc acgcactggt gcccccgcag 14160cactactacg atgcctgcgt gttcgacagc tgcttcatgc cgggctcgag cctggagtgc 14220gccagtctgc aggcctacgc agccctctgt gcccagcaga acatctgcct cgactggcgg 14280aaccacacgc atggggcctg cttggtggag tgcccatctc acagggagta ccaggcctgt 14340ggccctgcag aagagcccac gtgcaaatcc agctcctccc agcagaacaa cacagtcctg 14400gtggaaggct gcttctgtcc tgagggcacc atgaactacg ctcctggctt tgatgtctgc 14460gtgaagacct gcggctgtgt gggacctgac aatgtgccca gagagtttgg ggagcacttc 14520gagttcgact gcaagaactg tgtctgcctg gagggtggaa gtggcatcat ctgccaaccc 14580aagaggtgca gccagaagcc cgttacccac tgcgtggaag acggcaccta cctcgccacg 14640gaggtcaacc ctgccgacac ctgctgcaac attaccgtct gcaagtgcaa caccagcctg 14700tgcaaagaga agccctccgt gtgcccgctg ggattcgaag tgaagagcaa gatggtgcct 14760
ggaaggtgct gtcccttcta ctggtgtgag tccaaggggg tgtgtgttca cgggaatgct 14820gagtaccagc ccggttctcc agtttattcc tccaagtgcc aggactgcgt gtgcacggac 14880aaggtggaca acaacaccct gctcaacgtc atcgcctgca cccacgtgcc ctgcaacacc 14940tcctgcagcc ctggcttcga actcatggag gcccccgggg agtgctgtaa gaagtgtgaa 15000cagacgcact gtatcatcaa acggcccgac aaccagcacg tcatcctgaa gcccggggac 15060ttcaagagcg acccgaagaa caactgcaca ttcttcagct gcgtgaagat ccacaaccag 15120ctcatctcgt ccgtctccaa catcacctgc cccaactttg atgccagcat ttgcatcccg 15180ggctccatca cattcatgcc caatggatgc tgcaagacct gcacccctcg caatgagacc 15240agggtgccct gctccaccgt ccccgtcacc acggaggttt cgtacgccgg ctgcaccaag 15300accgtcctca tgaatcattg ctccgggtcc tgcgggacat ttgtcatgta ctcggccaag 15360gcccaggccc tggaccacag ctgctcctgc tgcaaagagg agaaaaccag ccagcgtgag 15420gtggtcctga gctgccccaa tggcggctcg ctgacacaca cctacaccca catcgagagc 15480tgccagtgcc aggacaccgt ctgcgggctc cccaccggca cctcccgccg ggcccggcgc 15540tcccctaggc atctggggag cgggtgagcg gggtgggcac agcccccttc actgccctcg 15600acagctttac ctcccccgga ccctctgagc ctcctaagct cggcttcctc tcttcagata 15660tttattgtct gagtctttgt tcagtccttg ctttccaata ataaactcag ggggacatgc 15720<210>14<211>15720<212>DNA<213>人<400>14caacccacac cgcccctgcc agccaccatg gggctgccac tagcccgcct ggcggctgtg 60tgcctggccc tgtctttggc agggggctcg gagctccaga cagagggcag aacccgatac 120cacggccgca acgtctgcag cacctggggc aacttccact acaagacctt cgacggggac 180gtcttccgct tccccggcct ctgcgactac aacttcgcct ccgactgccg aggctcctac 240aaggaatttg ctgtgcacct gaagcggggt ccgggccagg ctgaggcccc cgccggggtg 300gagtccatcc tgctgaccat caaggatgac accatctacc tcacccgcca cctggctgtg 360cttaacgggg ccgtggtcag caccccgcac tacagccccg ggctgctcat tgagaagagc 420gatgcctaca ccaaagtcta ctcccgcgcc ggcctcaccc tcatgtggaa ccgggaggat 480gcactcatgc tggagctgga cactaagttc cggaaccaca cctgtggcct ctgcggggac 540tacaacggcc tgcagagcta ttcagaattc ctctctgacg gcgtgctctt cagtcccctg 600gagtttggga acatgcagaa gatcaaccag cccgatgtgg tgtgtgagga tcccgaggag 660gaggtggccc ccgcatcctg ctccgagcac cgcgccgagt gtgagaggct gctgaccgcc 720gaggccttcg cggactgtca ggacctggtg ccgctggagc cgtatctgcg cgcctgccag 780caggaccgct gccggtgccc gggcggtgac acctgcgtct gcagcaccgt ggccgagttc 840tcccgccagt gctcccacgc cggcggccgg cccgggaact ggaggaccgc cacgctctgc 900
cccaagacct gccccgggaa cctggtgtac ctggagagcg gctcgccctg catggacacc 960tgctcacacc tggaggtgag cagcctgtgc gaggagcacc gcatggacgg ctgtttctgc1020ccagaaggca ccgtatatga cgacatcggg gacagtggct gcgttcctgt gagccagtgc1080cactgcaggc tgcacggaca cctgtacaca ccgggccagg agatcaccaa tgactgcgag1140cagtgtgtct gtaacgctgg ccgctgggtg tgcaaagacc tgccctgccc cggcacctgt1200gccctggaag gcggctccca catcaccacc ttcgatggga agacgtacac cttccacggg1260gactgctact atgtcctggc caagggtgac cacaacgatt cctacgctct cctgggcgag1320ctggccccct gtggctccac agacaagcag acctgcctga agacggtggt gctgctggct1380gacaagaaga agaatgcggt ggtcttcaag tccgatggca gtgtactgct caaccagctg1440caggtgaacc tgccccacgt gaccgcgagc ttctctgtct tccgcccgtc ttcctaccac1500atcatggtga gcatggccat tggcgtccgg ctgcaggtgc agctggcccc agtcatgcaa1560ctctttgtga cactggacca ggcctcccag gggcaggtgc agggcctctg cgggaacttc1620aacggcctgg aaggtgacga cttcaagacg gccagcgggc tggtggaggc cacgggggcc1680ggctttgcca acacctggaa ggcacagtca acctgccatg acaagctgga ctggttggac1740gatccctgct ccctgaacat cgagagcgcc aactacgccg agcactggtg ctccctcctg1800aagaagacag agaccccctt tggcaggtgc cactcggctg tggaccctgc tgagtattac1860aagaggtgca aatatgacac gtgtaactgt cagaacaatg aggactgcct gtgcgccgcc1920ctgtcctcct acgcgcgcgc ctgcaccgcc aagggcgtca tgctgtgggg ctggcgggag1980catgtctgca acaaggatgt gggctcctgc cccaactcgc aggtcttcct gtacaacctg2040accacctgcc agcagacctg ccgctccctc tccgaggccg acagccactg tctcgagggc2100tttgcgcctg tggacggctg cggctgccct gaccacacct tcctggacga gaagggccgc2160tgcgtacccc tggccaagtg ctcctgttac caccgcggtc tctacctgga ggcgggggat2220gtggtcgtca ggcaggaaga acgatgtgtg tgccgggatg ggcggctgca ctgtaggcag2280atccggctga tcggccagag ctgcacggcc ccaaagatcc acatggactg cagcaacctg2340actgcactgg ccacctcgaa gccccgagcc ctcagctgcc agacgctggc cgccggctat2400taccacacag agtgtgtcag tggctgtgtg tgccccgacg ggctgatgga tgacggccgg2460ggtggctgcg tggtggagaa ggaatgccct tgcgtccata acaacgacct gtattcttcc2520ggcgccaaga tcaaggtgga ctgcaatacc tgcacctgca agagaggacg ctgggtgtgc2580acccaggctg tgtgccatgg cacctgctcc atttacggga gtggccacta catcaccttt2640gatgggaagt actacgactt tgacggacac tgctcctacg tggctgttca ggactactgc2700ggccagaact cctcactggg ctcattcagc atcatcaccg agaacgtccc ctgtggcact2760acgggcgtca cctgctccaa ggccatcaag atcttcatgg ggaggacgga gctgaagttg2820gaagacaagc accgtgtggt gatccagcgt gatgagggtc accacgtggc ctacaccacg2880cgggaggtgg gccagtacct ggtggtggag tccagcacgg gcatcatcgt catctgggac2940aagaggacca ccgtgttcat caagctggct ccctcctaca agggcaccgt gtgtggcctg3000
tgtgggaact ttgaccaccg ctccaacaac gacttcacca cgcgggacca catggtggtg3060agcagcgagc tggacttcgg gaacagctgg aaggaggccc ccacctgccc agatgtgagc3120accaaccccg agccctgcag cctgaacccg caccgccgct cctgggccga gaagcagtgc3180agcatcctca aaagcagcgt gttcagcatc tgccacagca aggtggaccc caagcccttc3240tacgaggcct gtgtgcacga ctcgtgctcc tgtgacacgg gtggggactg tgagtgcttc3300tgctctgccg tggcctccta cgcccaggag tgtaccaaag agggggcctg cgtgttctgg3360aggacgccgg acctgtgccc catattctgc gactactaca accctccgca tgagtgtgag3420tggcactatg agccatgtgg gaaccggagc ttcgagacct gcaggaccat caacggcatc3480cactccaaca tctccgtgtc ctacctggag ggctgctacc cccggtgccc caaggacagg3540cccatctatg aggaggatct gaagaagtgt gtcactgcag acaagtgtgg ctgctatgtc3600gaggacaccc actacccacc tggagcatcg gttcccaccg aggagacctg caagtcctgc3660gtgtgtacca actcctccca agtcgtctgc aggccggagg aaggaaagat tcttaaccag3720acccaggatg gcgccttctg ctactgggag atctgtggcc ccaacgggac ggtggagaag3780cacttcaaca tctgttccat tacgacacgc ccgtccaccc tgaccacctt caccaccatc3840accctcccca ccacccccac ctccttcacc actaccacca ccaccaccac cccgacctcc3900agcacagttt tatcaacaac tccgaagctg tgctgcctct ggtctgactg gatcaatgag3960gaccacccca gcagtggcag cgacgacggt gaccgagaac catttgatgg ggtctgcggg4020gcccctgagg acatcgagtg caggtcggtc aaggatcccc acctcagctt ggagcagcat4080ggccagaagg tgcagtgtga tgtctctgtt gggttcattt gcaagaatga agaccagttt4140ggaaatggac catttggact gtgttacgac tacaagatac gtgtcaattg ttgctggccc4200atggataagt gtatcaccac tcccagccct ccaactacca ctcccagccc tccaccaacc4260acgacgacca cccttccacc aaccaccacc cccagccctc caaccaccac cacaaccacc4320cctccaccaa ccaccacccc cagccctcca ataaccacca cgaccacccc tctaccaacc4380accactccca gccctccaat aagcaccaca accacccctc caccaaccac cactcccagc4440cctccaacca ccactcccag ccctccaacc accactccca gccctccaac aaccaccaca4500accacccctc caccaaccac cactcccagc cctccaatga ctacgcccat cactccacca4560gccagcacta ccacccttcc accaaccacc actcccagcc ctccaacaac caccacaacc4620acccctccac caaccaccac tcccagtcct ccaacgacta cgcccatcac tccaccaacc4680agcactacta cccttccacc aaccaccact cccagccctc caccaaccac cacaaccacc4740cctccaccaa ccaccactcc cagccctcca acaaccacca ctcccagtcc tccaacaatc4800accacaacca cccctccacc aaccaccact cccagccctc caacaacgac cacaaccacc4860cctccaccaa ccaccactcc cagccctcca acgactacac ccatcactcc accaaccagc4920actaccaccc ttccaccaac caccactccc agccctccac caaccaccac aaccacccct4980ccaccaacca ccactcccag ccctccaaca accaccactc ccagccctcc aataaccacc5040
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acacccaccg gcacacagac cccaaccacg acacccatca ccaccaccac tacggtgacc 11340ccaaccccaa cacccaccgg cacacagacc ccaaccacga cacccatcac caccaccact 11400acggtgaccc caaccccaac acccaccggc acacagaccc caaccacgac acccatcacc 11460accaccacta cggtgacccc aaccccaaca cccaccggca cacagacccc aaccacgaca 11520cccatcacca ccaccactac ggtgacccca accccaacac ccaccggcac acagacccca 11580accacgacac ccatcaccac caccactacg gtgaccccaa ccccaacacc caccggcaca 11640cagaccccaa ccacgacacc catcaccacc accactacgg tgaccccaac cccaacaccc 11700accggcacac agaccccaac cacgacaccc atcaccacca ccactacggt gaccccaacc 11760ccaacaccca ccggcacaca gaccccaacc acgacaccca tcaccaccac cactacggtg 11820accccaaccc caacacccac cggcacacag accccaacca cgacacccat caccaccacc 11880actacggtga ccccaacccc aacacccacc ggcacacaga ccccaaccac gacacccatc 11940accaccacca ctacggtgac cccaacccca acacccaccg gcacacagac cccaaccacg 12000acacccatca ccaccaccac tacggtgacc ccaaccccaa cacccaccgg cacacagacc 12060ccaaccacga cacccatcac caccaccact acggtgaccc caaccccaac acccaccggc 12120acacagaccc caaccacgac acccatcacc accaccacta cggtgacccc aaccccaaca 12180cccaccggca cacagacccc aaccacgaca cccatcacca ccaccactac ggtgacccca 12240accccaacac ccaccggcac acagacccca accacgacac ccatcaccac caccactacg 12300gtgaccccaa ccccaacacc caccggcaca cagaccccaa ccacgacacc catcaccacc 12360accactacgg tgaccccaac cccaacaccc accggcacac agaccccaac cacgacaccc 12420atcaccacca ccactacggt gaccccaacc ccaacaccca ccggcacaca gaccccaacc 12480acgacaccca tcaccaccac cactacggtg accccaaccc caacacccac cggcacacag 12540accccaacca cgacacccat caccaccacc actacggtga ccccaacccc aacacccacc 12600ggcacacaga ccgggccccc cacccacaca agcacagcac cgattgctga gttgaccaca 12660tccaatcctc cgcctgagtc ctcaacccct cagacctctc ggtccacctc ttcccctctc 12720acggagtcaa ccacccttct gagtacccta ccacctgcca ttgagatgac cagcacggcc 12780ccaccctcca cacccacggc acccacgacc acgagcggag gccacacact gtctccaccg 12840cccagcacca ccacgtcccc tccaggcacc cccactcgcg gtaccacgac cgggtcatct 12900tcagccccca cccccagcac tgtgcagacg accaccacca gtgcctggac cccaacgccg 12960accccactct ccacacccag catcatcagg accacaggcc tgaggcccta cccttcctct 13020gtgcttatct gctgtgtcct gaacgacacc tactacgcac caggtgagga ggtgtacaac 13080ggcacatacg gagacacctg ttatttcgtc aactgctcac tgagctgtac gttggagttc 13140tataactggt cctgcccatc cacgccctcc ccaacaccca cgccctccaa gtcgacgccc 13200acgccttcca agccatcgtc cacgccctcc aagccgacgc ccggcaccaa gccccccgag 13260tgcccagact ttgatcctcc cagacaggag aacgagactt ggtggctgtg cgactgcttc 13320
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gtggtcctga gctgccccaa tggcggctcg ctgacacaca cctacaccca catcgagagc 15480tgccagtgcc aggacaccgt ctgcgggctc cccaccggca cctcccgccg ggcccggcgc 15540tcccctaggc atctggggag cgggtgagcg gggtgggcac agcccccttc actgccctcg 15600acagctttac ctcccccgga ccctctgagc ctcctaagct cggcttcctc tcttcagata 15660tttattgtct gagtctttgt tcagtccttg ctttccaata ataaactcag ggggacatgc 15720<210>15<211>3697<212>DNA<213>人<400>15agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga1020gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt1080tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt1140ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg1200acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg1260attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct1320ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta1380acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt1440gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct1500gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca1560
tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg1620ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat1680tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg1740tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg1800aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct1860ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat1920tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt1980agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca2040gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg2100aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc2160agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt2220ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa2280atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat2340gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta2400ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact2460gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt2520ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa2580agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa2640tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg2700tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc2760ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc2820tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc2880tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg2940gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg3000gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag3060acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta3120cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt3180tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt3240ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa3300catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc3360ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac3420atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt3480caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc3540actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt3600
ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca3660agaataaaca ctggttgtag tcagttttgt ttgttaa 3697<210>16<211>3697<212>DNA<213>人<400>16agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact120atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga180tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa240ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt300gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac360aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac420gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac480gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc540ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat600ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt660cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat720cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt780gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa840gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact900caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca960agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga 1020gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt 1080tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt 1140ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg 1200acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg 1260attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct 1320ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta 1380acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt 1440gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct 1500gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca 1560tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg 1620ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat 1680tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg 1740
tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg1800aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct1860ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat1920tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt1980agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca2040gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg2100aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc2160agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt2220ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa2280atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat2340gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta2400ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact2460gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt2520ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa2580agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa2640tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg2700tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc2760ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc2820tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc2880tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg2940gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg3000gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag3060acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta3120cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt3180tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt3240ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa3300catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc3360ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac3420atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt3480caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc3540actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt3600ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca3660agaataaaca ctggttgtag tcagttttgt ttgttaa 3697<210>17<211>1597
<212>DNA<213>人<400>17aacaaactgc acccactgaa ctccgcagct agcatccaaa tcagcccttg agatttgagg 60ccttggagac tcaggagttt tgagagcaaa atgacaacac ccagaaattc agtaaatggg120actttcctgg cagagccaat gaaaggccct attgctatgc aatctggtcc aaaaccactc180ttcaggagga tgtcttcact ggtgggcccc acgcaaagct tcttcatgag ggaatctaag240actttggggg ctgtccagat tatgaatggg ctcttccaca ttgccctggg gggtcttctg300atgatcccag cagggatcta tgcacccatc tgtgtgactg tgtggtaccc tctctgggga360ggcattatgt atattatttc cggatcactc ctggcagcaa cggagaaaaa ctccaggaag420tgtttggtca aaggaaaaat gataatgaat tcattgagcc tctttgctgc catttctgga480atgattcttt caatcatgga catacttaat attaaaattt cccatttttt aaaaatggag540agtctgaatt ttattagagc tcacacacca tatattaaca tatacaactg tgaaccagct600aatccctctg agaaaaactc cccatctacc caatactgtt acagcataca atctctgttc660ttgggcattt tgtcagtgat gctgatcttt gccttcttcc aggaacttgt aatagctggc720atcgttgaga atgaatggaa aagaacgtgc tccagaccca aatctaacat agttctcctg780tcagcagaag aaaaaaaaga acagactatt gaaataaaag aagaagtggt tgggctaact840gaaacatctt cccaaccaaa gaatgaagaa gacattgaaa ttattccaat ccaagaagag900gaagaagaag aaacagagac gaactttcca gaacctcccc aagatcagga atcctcacca960atagaaaatg acagctctcc ttaagtgatt tcttctgttt tctgtttcct tttttaaaca 1020ttagtgttca tagcttccaa gagacatgct gactttcatt tcttgaggta ctctgcacat 1080acgcaccaca tctctatctg gcctttgcat ggagtgacca tagctccttc tctcttacat 1140tgaatgtaga gaatgtagcc attgtagcag cttgtgttgt cacgcttctt cttttgagca 1200actttcttac actgaagaaa ggcagaatga gtgcttcaga atgtgatttc ctactaacct 1260gttccttgga taggcttttt agtatagtat ttttttttgt cattttctcc atcagcaacc 1320agggagactg cacctgatgg aaaagatata tgactgcttc atgacattcc taaactatct 1380tttttttatt ccacatctac gtttttggtg gagtcccttt tgcatcattg ttttaaggat 1440gataaaaaaa aaataacaac tagggacaat acagaaccca ttccatttat ctttctacag 1500ggctgacatt gtggcacatt cttagagtta ccacacccca tgagggaagc tctaaatagc 1560caacacccat ctgttttttg taaaaacagc atagctt1597<210>18<211>2907<212>DNA<213>人<400>18gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc60ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120
tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc1020gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg1080gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac1140cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg1200aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc1260atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg1320ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag1380ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc1440agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg1500ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg1560tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg1620ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact1680gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc1740tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc1800cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac1860tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac1920agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca1980ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata2040agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc2100tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac2160tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt2220
ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga2280gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc2340cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca2400gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc2460tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg2520ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca2580ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg2640acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc2700cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc2760ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc2820ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg2880gataaagaat aaagttctat ttattct2907<210>19<211>2907<212>DNA<213>人<400>19gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc1020gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg1080gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac1140
cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg1200aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc1260atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg1320ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag1380ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc1440agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg1500ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg1560tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg1620ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact1680gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc1740tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc1800cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac1860tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac1920agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca1980ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata2040agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc2100tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac2160tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt2220ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga2280gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc2340cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca2400gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc2460tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg2520ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca2580ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg2640acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc2700cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc2760ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc2820ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg2880gataaagaat aaagttctat ttattct2907<210>20<211>1347<212>DNA<213>人<400>20atggatccca aatatttcat cttaattttg ttttgtggac acctgaacaa tacatttttt 60
tcaaagacag agacaattac aacagagaag cagtcacagc ctaccttata cacatcatca 120atgtcacagg tattggctaa ttctcaaaac acaacaggga atcctttggg tcaaccaaca 180caattcagcg acactttttc tggacaatca atatcacctg ccaaagtcac tgctggacaa 240ccaacaccag ctgtctatac ctcttctgaa aaaccagaag cacatacttc tgctggacaa 300ccacttgcct acaacaccaa acaaccaaca ccaatagcca acacctcctc ccagcaagcc 360gtgttcacct ctgccagaca actaccatct gcccgtactt ctaccacaca accaccaaag 420tcatttgtct atacttttac tcaacaatca tcatctgtcc agatcccttc tagaaaacaa 480ataactgttc ataatccatc cacacaacca acatcaactg tcaaaaattc acctaggagt 540acaccaggat ttatcttaga tactaccagt aacaaacaaa ccccacaaaa aaacaattat 600aattcaatag ctgccatact aattggtgta cttctgactt ctatgttggt agctataatc 660atcattgtac tttggaaatg cttaaggaaa ccagttttaa atgatcaaaa ttgggcaggt 720agatctccat ttgctgatgg agaaacccct gacatttgta tggataacat cagagaaaat 780gaaatatcca caaaacgtac atcaatcatt tcacttacac cctggaaacc aagcaaaagc 840acacttttag cagatgactt agaaattaag ttgtttgaat caagtgaaaa cattgaagac 900tccaacaacc ccaaaacaga gaaaataaaa gatcaagtaa atggtacatc agaagatagt 960gctgatggtt caacagttgg aactgctgtt tcttcttcag atgatgcaga tctgcctcca1020ccacctcccc ttctggattt ggaaggacag gaaagtaacc aatctgacaa acccacaatg1080acaattgtat ctcctcttcc aaatgattct actagtctcc ctccatctct ggactgtctc1140aatcaagact gtggagatca taaatctgag ataatacaat catttccacc gcttgactca1200cttaacttgc ccctgccacc agtagatttt atgaaaaacc aagaagattc caaccttgag1260atccagtgtc aggagttctc tattcctccc aactctgatc aagatcttaa tgaatccctg1320ccacctccac ctgcagaact gttataa1347<210>21<211>2170<212>DNA<213>人<400>21ctgagggctc atccctctgc agagcgcggg gtcaccggga ggagacgcca tgacgcccgc 60cctcacagcc ctgctctgcc ttgggctgag tctgggcccc aggacccgcg tgcaggcagg 120gcccttcccc aaacccaccc tctgggctga gccaggctct gtgatcagct gggggagccc 180cgtgaccatc tggtgtcagg ggagcctgga ggcccaggag taccgactgg ataaagaggg 240aagcccagag cccttggaca gaaataaccc actggaaccc aagaacaagg ccagattctc 300catcccatcc atgacagagc accatgcggg gagataccgc tgccactatt acagctctgc 360aggctggtca gagcccagcg accccctgga gctggtgatg acaggattct acaacaaacc 420caccctctca gccctgccca gccctgtggt ggcctcaggg gggaatatga ccctccgatg 480tggctcacag aagggatatc accattttgt tctgatgaag gaaggagaac accagctccc 540
ccggaccctg gactcacagc agctccacag tggggggttc caggccctgt tccctgtggg 600ccccgtgaac cccagccaca ggtggaggtt cacatgctat tactattata tgaacacccc 660ccaggtgtgg tcccacccca gtgaccccct ggagattctg ccctcaggcg tgtctaggaa 720gccctccctc ctgaccctgc agggccctgt cctggcccct gggcagagcc tgaccctcca 780gtgtggctct gatgtcggct acgacagatt tgttctgtat aaggaggggg aacgtgactt 840cctccagcgc cctggccagc agccccaggc tgggctctcc caggccaact tcaccctggg 900ccctgtgagc ccctcccacg ggggccagta caggtgctat ggtgcacaca acctctcctc 960cgagtggtcg gcccccagcg accccctgaa catcctgatg gcaggacaga tctatgacac1020cgtctccctg tcagcacagc cgggccccac agtggcctca ggagagaacg tgaccctgct1080gtgtcagtca tggtggcagt ttgacacttt ccttctgacc aaagaagggg cagcccatcc1140cccactgcgt ctgagatcaa tgtacggagc tcataagtac caggctgaat tccccatgag1200tcctgtgacc tcagcccacg cggggaccta caggtgctac ggctcataca gctccaaccc1260ccacctgctg tctttcccca gtgagcccct ggaactcatg gtctcaggac actctggagg1320ctccagcctc ccacccacag ggccgccctc cacacctggt ctgggaagat acctggaggt1380tttgattggg gtctcggtgg ccttcgtcct gctgctcttc ctcctcctct tcctcctcct1440ccgacgtcag cgtcacagca aacacaggac atctgaccag agaaagactg atttccagcg1500tcctgcaggg gctgcggaga cagagcccaa ggacaggggc ctgctgagga ggtccagccc1560agctgctgac gtccaggaag aaaacctcta tgctgccgtg aaggacacac agtctgagga1620cagggtggag ctggacagtc agagcccaca cgatgaagac ccccaggcag tgacgtatgc1680cccggtgaaa cactccagtc ctaggagaga aatggcctct cctccctcct cactgtctgg1740ggaattcctg gacacaaagg acagacaggt ggaagaggac aggcagatgg acactgaggc1800tgctgcatct gaagcctccc aggatgtgac ctacgcccag ctgcacagct tgacccttag1860acggaaggca actgagcctc ctccatccca ggaaggggaa cctccagctg agcccagcat1920ctacgccact ctggccatcc actagcccgg ggggtacgca gaccccacac tcagcagaag1980gagactcagg actgctgaag gcacgggagc tgcccccagt ggacaccagt gaaccccagt2040cagcctggac ccctaacaca gaccatgagg agacgctggg aacttgtggg actcacctga2100ctcaaagatg actaatatcg tcccattttg gaaataaagc aacagacttc tcaacaatca2160atgagttaat 2170<210>22<211>1453<212>DNA<213>人<400>22gggagtgcat ccgccccaac ccttttcccc ctcgtctcct gtgagaattc cccgtcggat 60acgagcagcg tggccgttgg ctgcctcgca caggacttcc ttcccgactc catcactttc 120tcctggaaat acaagaacaa ctctgacatc agcagcaccc ggggcttccc atcagtcctg 180
agagggggca agtacgcagc cacctcacag gtgctgctgc cttccaagga cgtcatgcag 240ggcacagacg aacacgtggt gtgcaaagtc cagcacccca acggcaacaa agaaaagaac 300gtgcctcttc cagtgattgc cgagctgcct cccaaagtga gcgtcttcgt cccaccccgc 360gacggcttct tcggcaaccc ccgcaagtcc aagctcatct gccaggccac gggtttcagt 420ccccggcaga ttcaggtgtc ctggctgcgc gaggggaagc aggtggggtc tggcgtcacc 480acggaccagg tgcaggctga ggccaaagag tctgggccca cgacctacaa ggtgaccagc 540acactgacca tcaaagagag cgactggctc agccagagca tgttcacctg ccgcgtggat 600cacaggggcc tgaccttcca gcagaatgcg tcctccatgt gtgtccccga tcaagacaca 660gccatccggg tcttcgccat ccccccatcc tttgccagca tcttcctcac caagtccacc 720aagttgacct gcctggtcac agacctgacc acctatgaca gcgtgaccat ctcctggacc 780cgccagaatg gcgaagctgt gaaaacccac accaacatct ccgagagcca ccccaatgcc 840actttcagcg ccgtgggtga ggccagcatc tgcgaggatg actggaattc cggggagagg 900ttcacgtgca ccgtgaccca cacagacctg ccctcgccac tgaagcagac catctcccgg 960cccaaggggg tggccctgca caggcccgat gtctacttgc tgccaccagc ccgggagcag1020ctgaacctgc gggagtcggc caccatcacg tgcctggtga cgggcttctc tcccgcggac1080gtcttcgtgc agtggatgca gagggggcag cccttgtccc cggagaagta tgtgaccagc1140gccccaatgc ctgagcccca ggccccaggc cggtacttcg cccacagcat cctgaccgtg1200tccgaagagg aatggaacac gggggagacc tacacctgcg tggtggccca tgaggccctg1260cccaacaggg tcaccgagag gaccgtggac aagtccaccg gtaaacccac cctgtacaac1320gtgtccctgg tcatgtccga cacagctggc acctgctact gaccctgctg gcctgcccac1380aggctcgggg cggctggccg ctctgtgtgt gcatgcaaac taacccgtgt caacggggtg1440agatgttgca tct 1453<210>23<211>1192<212>DNA<213>人<400>23cagatccatc aggtccaagc tgtgttgact accactgctt ttcccttcgt ctcaattatg 60tcttggaaga aggctttgcg gatccctgga ggccttcggg tagcaactgt gaccttgatg 120ctggcgatgc tgagcacccc ggtggctgag ggcagagact ctcccgagga tttcgtgtac 180cagtttaagg gcatgtgcta cttcaccaac gggacggagc gcgtgcgtct tgtgaccaga 240tacatctata accgagagga gtacgcacgc ttcgacagcg acgtgggggt gtatcgggcg 300gtgacgccgc tggggccgcc tgacgccgag tactggaaca gccagaagga agtcctggag 360aggacccggg cggagttgga cacggtgtgc agacacaact accagttgga gctccgcacg 420accttgcagc ggcgagtgga gcccacagtg accatctccc catccaggac agaggccctc 480aaccaccaca acctgctggt ctgctcagtg acagatttct atccagccca gatcaaagtc 540
cggtggtttc ggaatgacca ggaggagaca actggcgttg tgtccacccc ccttattagg 600aacggtgact ggaccttcca gatcctggtg atgctggaaa tgactcccca gcgtggagac 660gtctacacct gccacgtgga gcaccccagc ctccagaacc ccatcatcgt ggagtggcgg 720gctcagtctg aatctgccca gagcaagatg ctgagtggca ttggaggctt cgtgctgggg 780ctgatcttcc tcgggctggg ccttattatc catcacagga gtcagaaagg gctcctgcac 840tgactcctga gactatttta actgggattg gttatcactt ttctgtaacg cctgcttgtc 900cctgcccaga attcccagct gcctgtgtca gcctgtcccc cgagatcaga gtcctaccgt 960ggctgtcacg cagccaccag gtcatctcct ttcatcccca cctcaaggct gatggctgtg1020accctgcttc ctgcactgac ccagagcctc tgcctgtgca cggccagctg cgtctactga1080ggccccaagg ggtttctgtt tctattctct cctcagactg ctcaagagaa gcacatgaaa1140accattacct gactttagag cttttttaca taattaaaca tgatcctgag tt1192<210>24<211>2048<212>DNA<213>人<400>24atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt1020gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga1080tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac1140tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt1260gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat1320acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt1380tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt1440ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc1500tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa1560cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca1620ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt1680taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta1740agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac1800ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata1860tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc1920atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc1980cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa2040ctaaaccg 2048<210>25<211>2048<212>DNA<213>人<400>25atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960
gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt1020gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga1080tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac1140tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag1200cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt1260gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat1320acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt1380tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt1440ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc1500tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa1560cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca1620ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt1680taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta1740agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac1800ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata1860tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc1920atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc1980cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa2040ctaaaccg 2048<210>26<211>2816<212>DNA<213>人<400>26tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720
aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat1020gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac1080aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt1140gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag1200aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat1260gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca1320attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc1380ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct1440gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc1500tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta1560tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga1620cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct1680ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag1740gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg1800gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa1860aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag1920aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga1980cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg2040tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc2100tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat2160gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta2220catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa2280ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt2340tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt2400aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta2460ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc2520agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt2580ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt2640ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt2700caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt2760
ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa2816<210>27<211>2816<212>DNA<213>人<400>27tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat1020gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac1080aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt1140gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag1200aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat1260gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca1320attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc1380ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct1440gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc1500tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta1560tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga1620cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct1680ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag1740gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg1800
gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa1860aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag1920aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga1980cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg2040tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc2100tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat2160gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta2220catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa2280ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt2340tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt2400aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta2460ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc2520agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt2580ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt2640ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt2700caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt2760ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa2816<210>28<211>3803<212>DNA<213>人<400>28ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840
ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct1020gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt1080gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga1140gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa1200ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac1260agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta1320caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg1380gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca1440agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat1500tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga1560gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag1620tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac1680agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt1740gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca1800tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc1860caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa1920tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg1980catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg2040cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga2100cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct2160cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg2220gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct2280gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc2340cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga2400ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag2460ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa2520tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga2580ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac2640ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac2700agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac2760ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc2820ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc2880ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca2940
ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg3000actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga3060gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga3120gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt3180tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc3240tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag3300cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc3360tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca3420gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc3480acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc3540cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga3600aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg3660cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag3720aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga3780caattaaaat ctttattcca gtg3803<210>29<211>3803<212>DMA<213>人<400>29ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960
tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct1020gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt1080gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga1140gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa1200ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac1260agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta1320caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg1380gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca1440agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat1500tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga1560gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag1620tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac1680agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt1740gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca1800tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc1860caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa1920tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg1980catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg2040cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga2100cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct2160cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg2220gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct2280gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc2340cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga2400ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag2460ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa2520tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga2580ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac2640ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac2700agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac2760ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc2820ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc2880ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca2940ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg3000
actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga3060gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga3120gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt3180tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc3240tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag3300cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc3360tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca3420gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc3480acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc3540cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga3600aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg3660cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag3720aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga3780caattaaaat ctttattcca gtg3803<210>30<211>2970<212>DNA<213>人<400>30ggggtaagga gttcaaggca gcgcccacac ccgggggctc tccgcaaccc gaccgcctgt 60ccgctccccc acttcccgcc ctccctccca cctactcatt cacccaccca cccacccaga 120gccgggacgg cagcccaggc gcccgggccc cgccgtctcc tcgccgcgat cctggacttc 180ctcttgctgc aggacccggc ttccacgtgt gtcccggagc cggcgtctca gcacacgctc 240cgctccgggc ctgggtgcct acagcagcca gagcagcagg gagtccggga cccgggcggc 300atctgggcca agttaggcgc cgccgaggcc agcgctgaac gtctccaggg ccggaggagc 360cgcggggcgt ccgggtctga gcctcagcaa atgggctccg acgtgcggga cctgaacgcg 420ctgctgcccg ccgtcccctc cctgggtggc ggcggcggct gtgccctgcc tgtgagcggc 480gcggcgcagt gggcgccggt gctggacttt gcgcccccgg gcgcttcggc ttacgggtcg 540ttgggcggcc ccgcgccgcc accggctccg ccgccacccc cgccgccgcc gcctcactcc 600ttcatcaaac aggagccgag ctggggcggc gcggagccgc acgaggagca gtgcctgagc 660gccttcactg tccacttttc cggccagttc actggcacag ccggagcctg tcgctacggg 720cccttcggtc ctcctccgcc cagccaggcg tcatccggcc aggccaggat gtttcctaac 780gcgccctacc tgcccagctg cctcgagagc cagcccgcta ttcgcaatca gggttacagc 840acggtcacct tcgacgggac gcccagctac ggtcacacgc cctcgcacca tgcggcgcag 900ttccccaacc actcattcaa gcatgaggat cccatgggcc agcagggctc gctgggtgag 960cagcagtact cggtgccgcc cccggtctat ggctgccaca cccccaccga cagctgcacc1020
ggcagccagg ctttgctgct gaggacgccc tacagcagtg acaatttata ccaaatgaca1080tcccagcttg aatgcatgac ctggaatcag atgaacttag gagccacctt aaagggccac1140agcacagggt acgagagcga taaccacaca acgcccatcc tctgcggagc ccaatacaga1200atacacacgc acggtgtctt cagaggcatt caggatgtgc gacgtgtgcc tggagtagcc1260ccgactcttg tacggtcggc atctgagacc agtgagaaac gccccttcat gtgtgcttac1320ccaggctgca ataagagata ttttaagctg tcccacttac agatgcacag caggaagcac1380actggtgaga aaccatacca gtgtgacttc aaggactgtg aacgaaggtt ttctcgttca1440gaccagctca aaagacacca aaggagacat acaggtgtga aaccattcca gtgtaaagct1500tgtcagcgaa agttctcccg gtccgaccac ctgaagaccc acaccaggac tcatacaggt1560gaaaagccct tcagctgtcg gtggccaagt tgtcagaaaa agtttgcccg gtcagatgaa1620ttagtccgcc atcacaacat gcatcagaga aacatgacca aactccagct ggcgctttga1680ggggtctccc tcggggaccg ttcagtgtcc caggcagcac agtgtgtgaa ctgctttcaa1740gtctgactct ccactcctcc tcactaaaaa ggaaacttca gttgatcttc ttcatccaac1800ttccaagaca agataccggt gcttctggaa actaccaggt gtgcctggaa gagttggtct1860ctgccctgcc tacttttagt tgactcacag gccctggaga agcagctaac aatgtctggt1920tagttaaaag cccattgcca tttggtctgg attttctact gtaagaagag ccatagctga1980tcatgtcccc ctgacccttc ccttcttttt ttatgctcgt tttcgctggg gatggaatta2040ttgtaccatt ttctatcatg gaatatttat aggccagggc atgtgtatgt gtctgctaat2100gtaaactttg tcatggtttc catttactaa cagcaacagc aagaaataaa tcagagagca2160aggcatcggg ggtgaatctt gtctaacatt cccgaggtca gccaggctgc taacctggaa2220agcaggatgt agttctgcca ggcaactttt aaagctcatg catttcaagc agctgaagaa2280agaatcagaa ctaaccagta cctctgtata gaaatctaaa agaattttac cattcagtta2340attcaatgtg aacactggca cactgctctt aagaaactat gaagatctga gatttttttg2400tgtatgtttt tgactctttt gagtggtaat catatgtgtc tttatagatg tacatacctc2460cttgcacaaa tggaggggaa ttcattttca tcactgggag tgtccttagt gtataaaaac2520catgctggta tatggcttca agttgtaaaa atgaaagtga ctttaaaaga aaatagggga2580tggtccagga tctccactga taagactgtt tttaagtaac ttaaggacct ttgggtctac2640aagtatatgt gaaaaaaatg agacttactg ggtgaggaaa tccattgttt aaagatggtc2700gtgtgtgtgt gtgtgtgtgt gtgtgtgttg tgttgtgttt tgttttttaa gggagggaat2760ttattattta ccgttgcttg aaattactgt gtaaatatat gtctgataat gatttgctct2820ttgacaacta aaattaggac tgtataagta ctagatgcat cactgggtgt tgatcttaca2880agatattgat gataacactt aaaattgtaa cctgcatttt tcactttgct ctcaattaaa2940gtctattcaa aaggaaaaaa aaaaaaaaaa 2970<210>31<211>2422
<212>DNA<213>人<400>31gtcagcctcc cttccaccgc catattgggc cactaaaaaa agggggctcg tcttttcggg 60gtgtttttct ccccctcccc tgtccccgct tgctcacggc tctgcgactc cgacgccggc120aaggtttgga gagcggctgg gttcgcggga cccgcgggct tgcacccgcc cagactcgga180cgggctttgc caccctctcc gcttgcctgg tcccctctcc tctccgccct cccgctcgcc240agtccatttg atcagcggag actcggcggc cgggccgggg cttccccgca gcccctgcgc300gctcctagag ctcgggccgt ggctcgtcgg ggtctgtgtc ttttggctcc gagggcagtc360gctgggcttc cgagaggggt tcgggccgcg taggggcgct ttgttttgtt cggttttgtt420tttttgagag tgcgagagag gcggtcgtgc agacccggga gaaagatgtc aaacgtgcga480gtgtctaacg ggagccctag cctggagcgg atggacgcca ggcaggcgga gcaccccaag540ccctcggcct gcaggaacct cttcggcccg gtggaccacg aagagttaac ccgggacttg600gagaagcact gcagagacat ggaagaggcg agccagcgca agtggaattt cgattttcag660aatcacaaac ccctagaggg caagtacgag tggcaagagg tggagaaggg cagcttgccc720gagttctact acagaccccc gcggcccccc aaaggtgcct gcaaggtgcc ggcgcaggag780agccaggatg tcagcgggag ccgcccggcg gcgcctttaa ttggggctcc ggctaactct840gaggacacgc atttggtgga cccaaagact gatccgtcgg acagccagac ggggttagcg900gagcaatgcg caggaataag gaagcgacct gcaaccgacg attcttctac tcaaaacaaa960agagccaaca gaacagaaga aaatgtttca gacggttccc caaatgccgg ttctgtggag 1020cagacgccca agaagcctgg cctcagaaga cgtcaaacgt aaacagctcg aattaagaat 1080atgtttcctt gtttatcaga tacatcactg cttgatgaag caaggaagat atacatgaaa 1140attttaaaaa tacatatcgc tgacttcatg gaatggacat cctgtataag cactgaaaaa 1200caacaacaca ataacactaa aattttaggc actcttaaat gatctgcctc taaaagcgtt 1260ggatgtagca ttatgcaatt aggtttttcc ttatttgctt cattgtacta cctgtgtata 1320tagtttttac cttttatgta gcacataaac tttggggaag ggagggcagg gtggggctga 1380ggaactgacg tggagcgggg tatgaagagc ttgctttgat ttacagcaag tagataaata 1440tttgacttgc atgaagagaa gcaattttgg ggaagggttt gaattgtttt ctttaaagat 1500gtaatgtccc tttcagagac agctgatact tcatttaaaa aaatcacaaa aatttgaaca 1560ctggctaaag ataattgcta tttattttta caagaagttt attctcattt gggagatctg 1620gtgatctccc aagctatcta aagtttgtta gatagctgca tgtggctttt ttaaaaaagc 1680aacagaaacc tatcctcact gccctcccca gtctctctta aagttggaat ttaccagtta 1740attactcagc agaatggtga tcactccagg tagtttgggg caaaaatccg aggtgcttgg 1800gagttttgaa tgttaagaat tgaccatctg cttttattaa atttgttgac aaaattttct 1860cattttcttt tcacttcggg ctgtgtaaac acagtcaaaa taattctaaa tccctcgata 1920tttttaaaga tctgtaagta acttcacatt aaaaaatgaa atatttttta atttaaagct 1980
tactctgtcc atttatccac aggaaagtgt tatttttaaa ggaaggttca tgtagagaaa2040agcacacttg taggataagt gaaatggata ctacatcttt aaacagtatt tcattgcctg2100tgtatggaaa aaccatttga agtgtacctg tgtacataac tctgtaaaaa cactgaaaaa2160ttatactaac ttatttatgt taaaagattt tttttaatct agacaatata caagccaaag2220tggcatgttt tgtgcatttg taaatgctgt gttgggtaga ataggttttc ccctcttttg2280ttaaataata tggctatgct taaaaggttg catactgagc caagtataat tttttgtaat2340gtgtgaaaaa gatgccaatt attgttacac attaagtaat caataaagaa aacttccata2400gctaaaaaaa aaaaaaaaaa aa 2422<210>32<211>1181<212>DNA<213>人<400>32ggcacgaggc ccgggccccc caaagtcccg gccgggccga gggtcggcgg ccgccggcgg 60gccgggcccg cgcacagcgc ccgcatgtac aacatgatgg agacggagct gaagccgccg120ggcccgcagc aaacttcggg gggcggcggc ggcaactcca ccgcggcggc ggccggcggc180aaccagaaaa acagcccgga ccgcgtcaag cggcccatga atgccttcat ggtgtggtcc240cgcgggcagc ggcgcaagat ggcccaggag aaccccaaga tgcacaactc ggagatcagc300aagcgcctgg gcgccgagtg gaaacttttg tcggagacgg agaagcggcc gttcatcgac360gaggctaagc ggctgcgagc gctgcacatg aaggagcacc cggattataa ataccggccc420cggcggaaaa ccaagacgct catgaagaag gataagtaca cgctgcccgg cgggctgctg480gcccccggcg gcaatagcat ggcgagcggg gtcggggtgg gcgccggcct gggcgcgggc540gtgaaccagc gcatggacag ttacgcgcac atgaacggct ggagcaacgg cagctacagc600atgatgcagg accagctggg ctacccgcag cacccgggcc tcaatgcgca cggcgcagcg660cagatgcagc ccatgcaccg ctacgacgtg agcgccctgc agtacaactc catgaccagc720tcgcagacct acatgaacgg ctcgcccacc tacagcatgt cctactcgca gcagggcacc780cctggcatgg ctcttggctc catgggttcg gtggtcaagt ccgaggccag ctccagcccc840cctgtggtta cctcttcctc ccactccagg gcgccctgcc aggccgggga cctccgggac900atgatcagca tgtatctccc cggcgccgag gtgccggaac ccgccgcccc cagcagactt960cacatgtccc agcactacca gagcggcccg gtgcccggca cggccattaa cggcacactg 1020cccctctcac acatgtgagg gccggacagc gaactggagg ggggagaaat tttcaaagaa 1080aaacgaggga aatgggaggg gtgcaaaaga ggagagtaag aaacagcatg gagaaaaccc 1140ggtacgctca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a 1181<210>33<211>1305<212>DNA<213>人
<400>33ggggccccgc gccggcccgc gccctgccca gtgcggcctc cttccacccg ccgctgcctg 60gcccgcgccg tccggccgag ctgcccggcg ggctggtccc cgcgcccgag ccgcccggcc120gggaccccga acaaggccga gatgacttcc aaggaggacg gcaaggcggc gccgggggag180gagcggcgcc gcagcccgct ggaccacctg cctccgcctg ccaactccaa caagccagac240gccgttcagc atcgaggaca tcctcaacaa gccgtctgtg cggagaagtt actcgctgcg300tggggcggcg cacctgctgg ccgccgcgga caagcacgcg cagggcggct tgccctggcg360ggccgcgcgc tgctctcgaa gacctcgccg ctgtgcgcgc tggaggagct cgccagcaag420acgtttaagg ggctggaggt cagcgttctg caggcagccg aaggccgcga cggtatgacc480atctttgggc agcggcagac ccctaagaag cggcgaaagt cgcgcacggc cttcaccaac540caccagatct atgaattgga aaagcgcttt ctataccaga agtacctgtc ccccgccgat600cgcgaccaaa tcgcgcagca gctgggcctc accaacgcgc aagtcatcac ctggttccag660aatcggcgcg ctaagctcaa gcgggaactg gaggagatga aggccgacgt ggagtccccc720aagaaactgg gccccagcgg gcagatggac atcgtggcgc tggccgaact cgagcagaac780tcggaggcca cagccggcgg tggcggcggc tgcggcaggg ccaagtcgag gcccggctct840ccggtcctcc ccccaggcgc cccgaaggcc cccgggcgct gcgccctgca gctctcgcct900gcctctccgc tcacggacca gccggccagc agccaggact gctcggagga cgaggaagac960gaagagatcg acgtggacga ttgagcggcg ccccgggtct tccgccgccc tgggctccta 1020gcgctcgaaa gcccaacgcc tcccggaccg gaccgccgag gggagctggg acctcctctg 1080ccactcccgc ctcctcccct gtccccggac tcggctcctg gcagccgcct cttccctctc 1140gaagcaataa acccaggctg gccggccggg ccggccgcca ccagcggcct ccgccgcccc 1200ggaagccctc gccgagcaat tctgtatggc ttctatataa atatttaaac ctatatagcg 1260ggttctcccc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa 1305<210>34<211>1926<212>DNA<213>人<400>34gctggagcat cccgctctgg tgccgctgca gccggcagag atggttgagc tcatgttccc 60gctgttgctc ctccttctgc ccttccttct gtatatggct gcgccccaaa tcaggaaaat120gctgtccagt ggggtgtgta catcaactgt tcagcttcct gggaaagtag ttgtggtcac180aggagctaat acaggtatcg ggaaggagac agccaaagag ctggctcaga gaggagctcg240agtatattta gcttgccggg atgtggaaaa gggggaattg gtggccaaag agatccagac300cacgacaggg aaccagcagg tgttggtgcg gaaactggac ctgtctgata ctaagtctat360tcgagctttt gctaagggct tcttagctga ggaaaagcac ctccacgttt tgatcaacaa420tgcaggagtg atgatgtgtc cgtactcgaa gacagcagat ggctttgaga tgcacatagg480
agtcaaccac ttgggtcact tcctcctaac ccatctgctg ctagagaaac taaaggaatc 540agccccatca aggatagtaa atgtgtcttc cctcgcacat cacctgggaa ggatccactt 600ccataacctg cagggcgaga aattctacaa tgcaggcctg gcctactgtc acagcaagct 660agccaacatc ctcttcaccc aggaactggc ccggagacta aaaggctctg gcgttacgac 720gtattctgta caccctggca cagtccaatc tgaactggtt cggcactcat ctttcatgag 780atggatgtgg tggcttttct cctttttcat caagactcct cagcagggag cccagaccag 840cctgcactgt gccttaacag aaggtcttga gattctaagt gggaatcatt tcagtgactg 900tcatgtggca tgggtctctg cccaagctcg taatgagact atagcaaggc ggctgtggga 960cgtcagttgt gacctgctgg gcctcccaat agactaacag gcagtgcagt tggacccaag1020agaagactgc agcagactac acagtacttc ttgtcaaaat gattctcctt caaggttttc1080aaaaccttta gcacaaagag agcaaaacct tccagccttg cctgcttggt gtccagttaa1140aactcagtgt actgccagat tcgtctaaat gtctgtcatg tccagattta ctttgcttct1200gttactgcca gagttactag agatatcata ataggataag aagaccctca tatgacctgc1260acagctcatt ttccttctga aagaaactac tacctaggag aatctaagct atagcaggga1320tgatttatgc aaatttgaac tagcttcttt gttcacaatt cagttcctcc caaccaacca1380gtcttcactt caagagggcc acactgcaac ctcagcttaa catgaataac aaagactggc1440tcaggagcag ggcttgccca ggcatggtgg atcaccggag tcagtagttc aagaccagcc1500tggccaacat ggtgaaaccc cacctctact aaaaattgtg tatatctttg tgtgtcttcc1560tgtttatgtg tgccaaggga gtattttcac aaagttcaaa acagccacaa taatcagaga1620tggagcaaac cagtgccatc cagtctttat gcaaatgaaa tgctgcaaag ggaagcagat1680tctgtatatg ttggtaacta cccaccaaga gcacatgggt agcagggaag aagtaaaaaa1740agagaaggag aatactggaa gataatgcac aaaatgaagg gactagttaa ggattaacta1800gccctttaag gattaactag ttaaggatta atagcaaaag acattaaata tgctaacata1860gctatggagg aattgagggc aagcacccag gactgatgag gtcttaacaa aaaccagtgt1920ggcaaa 1926<210>35<211>1195<212>DNA<213>人<400>35ccgagactca cggtcaagct aaggcgaaga gtgggtggct gaagccatac tattttatag 60aattaatgga aagcagaaaa gacatcacaa accaagaaga actttggaaa atgaagccta 120ggagaaattt agaagaagac gattatttgc ataaggacac gggagagacc agcatgctaa 180aaagacctgt gcttttgcat ttgcaccaaa cagcccatgc tgatgaattt gactgccctt 240cagaacttca gcacacacag gaactctttc cacagtggca cttgccaatt aaaatagctg 300ctattatagc atctctgact tttctttaca ctcttctgag ggaagtaatt caccctttag 360
caacttccca tcaacaatat ttttataaaa ttccaatcct ggtcatcaac aaagtcttgc 420caatggtttc catcactctc ttggcattgg tttacctgcc aggtgtgata gcagcaattg 480tccaacttca taatggaacc aagtataaga agtttccaca ttggttggat aagtggatgt 540taacaagaaa gcagtttggg cttctcagtt tcttttttgc tgtactgcat gcaatttata 600gtctgtctta cccaatgagg cgatcctaca gatacaagtt gctaaactgg gcatatcaac 660aggtccaaca aaataaagaa gatgcctgga ttgagcatga tgtttggaga atggagattt 720atgtgtctct gggaattgtg ggattggcaa tactggctct gttggctgtg acatctattc 780catctgtgag tgactctttg acatggagag aatttcacta tattcagagc aagctaggaa 840ttgtttccct tctactgggc acaatacacg cattgatttt tgcctggaat aagtggatag 900atataaaaca atttgtatgg tatacacctc caacttttat gatagctgtt ttccttccaa 960ttgttgtcct gatatttaaa agcatactat tcctgccatg cttgaggaag aagatactga1020agattagaca tggttgggaa gacgtcacca aaattaacaa aactgagata tgttcccagt1080tgtagaatta ctgtttacac acatttttgt tcaatattga tatattttat caccaacatt1140tcaagtttgt atttgttaat aaaatgatta ttcaaggaaa aaaaaaaaaa aaaaa 1195<210>36<211>3414<212>DNA<213>人<400>36gcttacacag tatggccggc gacattagct agcgctcgct ctactctctc taacgggaaa 60gcagcggaat acaagagact gaactgtatc tgcctctatt tccaaaagac tcacgttcaa120ctttcgctca cacaaagccg ggaaaatttt attagtcctt tttttaaaaa aagttaatat180aaaattatag caaaaaaaaa aaggaacctg aactttagta acacagctgg aacaatcgca240gcggcggcgg cagcggcggg agaagaggtt taatttagtt gattttctgt ggttgttggt300tgttcgctag tctcacggtg atggaagctg cacatttttt cgaagggacc gagaagctgc360tggaggtttg gttctcccgg cagcagcccg acgcaaacca aggatctggg gatcttcgca420ctatcccaag atctgagtgg gacatacttt tgaaggatgt gcaatgttca atcataagtg480tgacaaaaac tgacaagcag gaagcttatg tactcagtga gagtagcatg tttgtctcca540agagacgttt cattttgaag acatgtggta ccaccctctt gctgaaagca ctggttcccc600tgttgaagct tgctagggat tacagtgggt ttgactcaat tcaaagcttc ttttattctc660gtaagaattt catgaagcct tctcaccaag ggtacccaca ccggaatttc caggaagaaa720tagagtttct taatgcaatt ttcccaaatg gagcaggata ttgtatggga cgtatgaatt780ctgactgttg gtacttatat actctggatt tcccagagag tcgggtaatc agtcagccag840atcaaacctt ggaaattctg atgagtgagc ttgacccagc agttatggac cagttctaca900tgaaagatgg tgttactgca aaggatgtca ctcgtgagag tggaattcgt gacctgatac960caggttctgt cattgatgcc acaatgttca atccttgtgg gtattcgatg aatggaatga 1020
aatcggatgg aacttattgg actattcaca tcactccaga accagaattt tcttatgtta1080gctttgaaac aaacttaagt cagacctcct atgatgacct gatcaggaaa gttgtagaag1140tcttcaagcc aggaaaattt gtgaccacct tgtttgttaa tcagagttct aaatgtcgca1200cagtgcttgc ttcgccccag aagattgaag gttttaagcg tcttgattgc cagagtgcta1260tgttcaatga ttacaatttt gtttttacca gttttgctaa gaagcagcaa caacagcaga1320gttgattaag aaaaatgaag aaaaaacgca aaaagagaac acatgtagaa ggtggtggat1380gctttctaga tgtcgatgct gggggcagtg ctttccataa ccaccactgt gtagttgcag1440aaagccctag atgtaatgat agtgtaatca ttttgaattg tatgcattat tatatcaagg1500agttagatat cttgcatgaa tgctctcttc tgtgtttagg tattctctgc cactcttgct1560gtgaaattga agtggatgta gaaaaaacct tttactatat gaaactttac aacacttgtg1620aaagcaactc aatttggttt atgcacagtg taatatttct ccaagtatca tccaaaattc1680cccacagaca aggctttcgt cctcattagg tgttggcctc agcctaaccc tctaggactg1740ttctattaaa ttgctgccag aattttacat ccagttacct ccactttcta gaacatattc1800tttactaatg ttattgaaac caatttctac ttcatactga tgtttttgga aacagcaatt1860aaagtttttc ttccatagtt gagtccttag aaaatgattc cagttactca ttttgcatat1920tgctatttaa cattattgga ccctgcattt atagtccttt gatttcttcc ctctccctgg1980tgtctccccc aagaccccaa ataaagcaat accctgttaa cactgtgggt ttatatacta2040attctatacc ccagatgggg aattaggggg gagatggtcc ctgggcttaa tattctttaa2100agggcatggg aatttagcct ctcttttatt gtaatgtgct cttttggaaa atagttggtt2160agcagggaga ccagagttgt agattgagat tgggtgtact ggctgttctg tggaaaacat2220acattctgtg ttcctcgaat aagtgaaatt gagcttctaa tgagatgcac ccctttacta2280acttgatgat gatataaaat tcatttttat ttagttaatt accagagaga tttagcataa2340ttttgcttct ggattcagta aatcaagtca gcttggatca ttcaccttaa cttttccttt2400agcagccctt tccactagtt tcccattaag tagtgttcta taaactttga tccaaagcag2460aatcaatgtc ttttccatct cgtgacttaa agttctgtga ctgtgatgca tgtgagtgtt2520ccgacttcat ctgttcctct taactacggt gtttccctta ccgatcggca ttcataggat2580gaaatgaatg actgtcccag aatgagaatt tgtccagatt attcagataa acatcataaa2640gagaataaca ttataaataa gtagaatatg aataaataga ataataaaat tccaaaatac2700tcaatgggaa atgactagta atataggctt tcaagagttg gtacctttac gtatatttgc2760agattctctg ggattttaag gaactgagaa aacagaaaag ttgactaaat tttatatttc2820ttgtcctcta aatattttga taatttctgg attgatgcag tgatgttttt cgttccttgt2880atttataaat gaaaaccttt ttttggtgtt tctaaaccta aaatctactt ggtttgaaat2940caagtggttg gaacactgtt tgacttttat ttgaagcatg ttgttgattg aaaatttcat3000tgaggaagtt ttcaatcagt gtgatcagtt tgattctgta atgagcacag cacctaatat3060tttgaggagc tctgttttga ggaccaatgc ttaaggtgga ccttgttgct aaacaatatc3120
ccaatagatt tgttgacttg aggtctggtt tggttttgtt tttgttttgt tttggttttg3180ttttgtttcc caatagaatt aagaattcta atgttgaaaa actgtataaa tttttatggg3240acaaagccta gaaaagagaa atgtagtttg aatcataatc taaatcatcg tatgatagga3300aggaaaagtt ttggtgccat aatttctcct ttcactggtg ttggacttaa atcagttgaa3360atgtatttct gtaccacaat ttacgcttca ataaaagttt aattgtctag tgag 3414<210>37<211>3287<212>DNA<213>人<400>37agactgaggc ggaggcagcc ccgcgccgcg ccggacccga gcatatttca ttttctgtca 60ttggactttg agccattaga accatgagca actacagtgt gtcactggtt ggcccagctc 120cttggggttt ccggctgcag ggcggtaagg atttcaacat gcctctgaca atctctagtc 180taaaagatgg cggcaaggca gcccaggcaa atgtaagaat aggcgatgtg gttctcagca 240ttgatggaat aaatgcacaa ggaatgactc atcttgaagc ccagaataag attaagggtt 300gtacaggctc tttgaatatg actctgcaaa gagcatctgc tgcacccaag cctgagccgg 360ttcctgttca aaagggagaa cctaaagaag tagttaaacc tgtgcccatt acatctcctg 420ctgtgtccaa agtcacttcc acaaacaaca tggcctacaa taaggcacca cggccttttg 480gttctgtgtc ttcaccaaaa gtcacatcca tcccatcacc atcgtctgcc ttcaccccag 540cccatgcgac cacctcatca catgcttccc cttcacccgt ggctgccgtc actcctcccc 600tgttcgctgc atctggactg catgctaatg ccaatcttag tgctgaccag tctccatctg 660cactgagcgc tggtaaaact gcagttaatg tcccacggca gcccacagtc accagcgtgt 720gttccgagac ttctcaggag ctagcagagg gacagagaag aggatcccag ggtgacagta 780aacagcaaaa tggcccacca agaaaacaca ttgtggagcg ctatacagag ttttatcatg 840tacccactca cagtgatgcc agcaagaaga gactgattga ggatactgaa gactggcgtc 900caagaactgg aacaactcag tctcgctctt tccgaatcct tgcccagatc actgggactg 960aacatttgaa agaatctgaa gccgataata caaagaaggc aaataactct caggagcctt1020ctccgcagtt ggcttccttg gtagcttcca cacggagcat gcccgagagc ctggacagcc1080caacctctgg cagaccaggg gttaccagcc tcacaactgc agctgccttc aagcctgtag1140gatccactgg cgtcatcaag tcaccaagct ggcaacggcc aaaccaagga gtaccttcca1200ctggaagaat ctcaaacagc gctacttact caggatcagt ggcaccagcc aactcagctt1260tgggacaaac ccagccaagt gaccaggaca ctttagtgca aagagctgag cacattccag1320cagggaaacg aactccgatg tgcgcccatt gtaaccaggt catcagagga ccattcttag1380tggcactggg gaaatcttgg cacccagaag aattcaactg cgctcactgc aaaaatacaa1440tggcctacat tggatttgta gaggagaaag gagccctgta ttgtgagctg tgctatgaga1500aattctttgc ccctgaatgt ggtcgatgcc aaaggaagat ccttggagaa gtcatcaatg1560
cgttgaaaca aacttggcat gtttcctgtt ttgtgtgtgt agcctgtgga aagcccattc1620ggaacaatgt ttttcacttg gaggatggtg aaccctactg tgagactgat tattatgccc1680tctttggtac tatatgccat ggatgtgaat ttcccataga agctggtgac atgttcctgg1740aagctctggg ctacacctgg catgacactt gctttgtatg ctcagtgtgt tgtgaaagtt1800tggaaggtca gacctttttc tccaagaagg acaagcccct gtgtaagaaa catgctcatt1860ctgtgaattt ttgaaagtca acagttcagg agaagagaag gaatttgaag agaaaaagga1920aaattaaaat tactaattaa tttttagatt caatatttat atggagtttt gaaaaataat1980agtggccctg aaggaataaa ttccagcttt aaaaaccaag tctgaggaaa tatttggctt2040cataaagtaa agagacggtt tggcatttat tattactttt tcctgtattt tatgcccata2100aaataagctt tataaaaacc aatttcctga tggactatta aattcatctt agaataaatt2160agtgaagaat ttaattttag aataaataat ccaatctgaa ataattatac cttctttcct2220tgttaggtag ttatgagtaa atctgcaaaa ggcaatgaaa atgccttaaa ttttatcaat2280aacagaatta ttgtatttaa aaaaaaacta atacttatct ttaaaatagt aaataggatt2340ttaaacagag aattttatca gtaataggtg tcagttttta aaaaattgct tgtaggctga2400gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ccaaggtggg tggaccacat2460gaggtcagga gtttgagatc agcctggcca acatggtgaa accccatctc tactaaaaat2520acaaaaatta gccggacgca gtggcacgcg cctgtaatcc cagctactca agaggctgag2580gcacgagaat cacttgaacc cgggagggag aggttgcagt gagccaagat cgtaccactg2640cactccagcc tgggtgacag agtgagactc cgtctccaaa aaaaaacttt gcttgtatat2700tatttttgcc ttacagtgga tcattctagt aggaaaggac aataagattt tttatcaaaa2760tgtgtcatgc cagtaagaga tgttatattc ttttcttatt tcttccccac ccaaaaataa2820gctaccatat agcttataag tctcaaattt ttgcctttta ctaaaatgtg attgtttctg2880ttcattgtgt atgcttcatc acctatatta ggcaaattcc attttttccc ttgcgctaag2940gtaaagattt aattaaataa ttttggcctc tcatagtttt ctctctcttt aaagagaata3000aatagagggc caggtgtggt ggctcacgcc tgtgatccca gcactttggg aggccaagac3060gggcggatca tgaggtcaag agatcaagat catcctggcc aacatggtga aaccctgtct3120ctactaaaaa tacaaaaatg agctgggcat ggtggggcgt gcctgtagtc ccatgtactt3180gggaggctga ggcaggaaaa ttcttgaacc caggagacgg aagttgcagt gagctgagat3240cacaccactg cactccagcc tggtgacaga gcaagactcc ggctctt 3287<210>38<211>1254<212>DNA<213>人<400>38atggcagtgg agaccacggt ccacactcac ctctctgcgt ctccaccgca gggctctccc 60tacgaccaca cacccggcat ggcgggctcc ttggggtacc atccttacgc ggcgcccctg120
ggatcgtacc cttacgggga cccagcgtac cggaagaacg ccacaaggga cgccacggct 180accctcaagg cctggctcaa cgagcaccgc aagaacccct accccaccaa gggcgagaag 240atcatgctgg ccatcatcac caagatgacc ctcacccagg tgtccacctg gttcgccaac 300gcgcgccggc gcctcaagaa agagaataaa atgacgtgga cgccgcggaa ccgcagcgag 360gacgaggaag aggaggagaa cattgacctg gagaagaacg acgaggacga gccccagaag 420cccgaggaca agggcgaccc cgagggcccc gaagcaggag gagctgagca gaaggcggct 480tcgggctgcg aacggcttca gggaccaccc acccctgcag gcaaggagac ggagggcagc 540ctcagcgact cggattttaa ggagccgccc tcggagggcc gcctcgacgc gctgcagggc 600cccccccgca ccggcgggcc ctccccggct gggccagcgg cggcgcggct ggcggaggac 660ccggcccctc actaccccgc cggagcgccg gcgcccggcc cgcatccagc cgcgggcgag 720gtgcctccgg gtcccggcgg gccctcggtt atccattcgc cgcctccgcc gccgcctcct 780gcggtgctcg ccaagcccaa actgtggtct ttggcagaga tcgccacatt gtcggacaag 840gtcaaggacg ggggcggcgg gaacgagggc tctccatgcc caccgtgtcc cgggcccata 900gccgggcaag ccctaggagg cagccgggcg tcgccggccc cggcgccgtc acgctcgccc 960tcggcgcagt gtccttttcc aggcgggacg gtgctgtccc ggcctctcta ctacaccgcg1020cccttctatc ccggctacac gaactatggc tccttcggac accttcatgg ccacccgggg1080cccgggccag gccccacaac cggtccgggg tctcatttca atggattaaa ccagaccgtg1140ttgaaccgag cggacgcttt ggctaaagac ccgaaaatgt tgcggagcca gtctcagcta1200gacctgtgca aagactctcc ctatgaattg aagaaaggta tgtccgacat ttaa 1254<210>39<211>2560<212>DNA<213>人<400>39gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc120caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct180tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc240ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg300ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc360atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca420ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg480ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca540gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt600gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca660gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg720
caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct1020ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat1080caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc1140cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc1200ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta1260tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat1320ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag1380cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac1440agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg1500cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa1560tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca1620gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa1680caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg1740tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat1800ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc1860aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct1920gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac1980atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca2040gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt2100aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc2160aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt2220aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac2280agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca2340tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag2400cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg2460atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag2520ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560<210>40<211>2560<212>DNA<213>人
<400>40gaattccggc cagaagaaat ctggcctcgg aacacgccat tctccgcgcc gcttccaata 60accactaaca tccctaacga gcatccgagc cgagggctct gctcggaaat cgtcctggcc 120caactcggcc cttcgagctc tcgaagatta ccgcatctat tttttttttc ttttttttct 180tttcctagcg cagataaagt gagcccggaa agggaaggag ggggcgggga caccattgcc 240ctgaaagaat aaataagtaa ataaacaaac tggctcctcg ccgcagctgg acgcggtcgg 300ttgagtccag gttgggtcgg acctgaaccc ctaaaagcgg aaccgcctcc cgccctcgcc 360atcccggagc tgagtcgccg gcggcggtgg ctgctgccag acccggagtt tcctctttca 420ctggatggag ctgaactttg ggcggccaga gcagcacagc tgtccgggga tcgctgcacg 480ctgagctccc tcggcaagac ccagcggcgg ctcgggattt ttttgggggg gcggggacca 540gccccgcgcc ggcaccatgt tcctggcgac cctgtacttc gcgctgccgc tcttggactt 600gctcctgtcg gccgaagtga gcggcggaga ccgcctggat tgcgtgaaag ccagtgatca 660gtgcctgaag gagcagagct gcagcaccaa gtaccgcacg ctaaggcagt gcgtggcggg 720caaggagacc aacttcagcc tggcatccgg cctggaggcc aaggatgagt gccgcagcgc 780catggaggcc ctgaagcaga agtcgctcta caactgccgc tgcaagcggg gtatgaagaa 840ggagaagaac tgcctgcgca tttactggag catgtaccag agcctgcagg gaaatgatct 900gctggaggat tccccatatg aaccagttaa cagcagattg tcagatatat tccgggtggt 960cccattcata tcagatgttt ttcagcaagt ggagcacatt cccaaaggga acaactgcct1020ggatgcagcg aaggcctgca acctcgacga catttgcaag aagtacaggt cggcgtacat1080caccccgtgc accaccagcg tgtccaacga tgtctgcaac cgccgcaagt gccacaaggc1140cctccggcag ttctttgaca aggtcccggc caagcacagc tacggaatgc tcttctgctc1200ctgccgggac atcgcctgca cagagcggag gcgacagacc atcgtgcctg tgtgctccta1260tgaagagagg gagaagccca actgtttgaa tttgcaggac tcctgcaaga cgaattacat1320ctgcagatct cgccttgcgg atttttttac caactgccag ccagagtcaa ggtctgtcag1380cagctgtcta aaggaaaact acgctgactg cctcctcgcc tactcggggc ttattggcac1440agtcatgacc cccaactaca tagactccag tagcctcagt gtggccccat ggtgtgactg1500cagcaacagt gggaacgacc tagaagagtg cttgaaattt ttgaatttct tcaaggacaa1560tacatgtctt aaaaatgcaa ttcaagcctt tggcaatggc tccgatgtga ccgtgtggca1620gccagccttc ccagtacaga ccaccactgc cactaccacc actgccctcc gggttaagaa1680caagcccctg gggccagcag ggtctgagaa tgaaattccc actcatgttt tgccaccgtg1740tgcaaattta caggcacaga agctgaaatc caatgtgtcg ggcaatacac acctctgtat1800ttccaatggt aattatgaaa aagaaggtct cggtgcttcc agccacataa ccacaaaatc1860aatggctgct cctccaagct gtggtctgag cccactgctg gtcctggtgg taaccgctct1920gtccacccta ttatctttaa cagaaacatc atagctgcat taaaaaaata caatatggac1980atgtaaaaag acaaaaacca agttatctgt ttcctgttct cttgtatagc tgaaattcca2040
gtttaggagc tcagttgaga aacagttcca ttcaactgga acattttttt ttttcctttt 2100aagaaagctt cttgtgatcc ttcggggctt ctgtgaaaaa cctgatgcag tgctccatcc 2160aaactcagaa ggctttggga tatgctgtat tttaaaggga cagtttgtaa cttgggctgt 2220aaagcaaact ggggctgtgt tttcgatgat gatgatcatc atgatcatga tgattttaac 2280agttttactt ctggcctttc ctagctagag aaggagttaa tatttctaag gtaactccca 2340tatctccttt aatgacattg atttctaatg atataaattt cagcctacat tgatgccaag 2400cttttttgcc acaaagaaga ttcttaccaa gagtgggctt tgtggaaaca gctggtactg 2460atgttcacct ttatatatgt actagcattt tccacgctga tgtttatgta ctgtaaacag 2520ttctgcactc ttgtacaaaa gaaaaaacca cccggaattc 2560<210>41<211>2439<212>DNA<213>人<400>41cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg1020gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg1080gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga1140cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa1200ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca1260gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag1320
cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc1380taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga1440cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca1500ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa1560ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag1620ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt1680ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt1740gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac1800ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt1860catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga1920gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa1980cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg2040aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt2100gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt2160cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat2220catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca2280tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc2340gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag2400aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439<210>42<211>2439<212>DNA<213>人<400>42cagcacccag ctccccgcca ccgccatggt ccccgacacc gcctgcgttc ttctgctcac 60cctggctgcc ctcggcgcgt ccggacaggg ccagagcccg ttgggctcag acctgggccc 120gcagatgctt cgggaactgc aggaaaccaa cgcggcgctg caggacgtgc gggactggct 180gcggcagcag gtcagggaga tcacgttcct gaaaaacacg gtgatggagt gtgacgcgtg 240cgggatgcag cagtcagtac gcaccggcct acccagcgtg cggcccctgc tccactgcgc 300gcccggcttc tgcttccccg gcgtggcctg catccagacg gagagcggcg gccgctgcgg 360cccctgcccc gcgggcttca cgggcaacgg ctcgcactgc accgacgtca acgagtgcaa 420cgcccacccc tgcttccccc gagtccgctg tatcaacacc agcccggggt tccgctgcga 480ggcttgcccg ccggggtaca gcggccccac ccaccagggc gtggggctgg ctttcgccaa 540ggccaacaag caggtttgca cggacatcaa cgagtgtgag accgggcaac ataactgcgt 600ccccaactcc gtgtgcatca acacccgggg ctccttccag tgcggcccgt gccagcccgg 660cttcgtgggc gaccaggcgt ccggctgcca gcgcggcgca cagcgcttct gccccgacgg 720
ctcgcccagc gagtgccacg agcatgcaga ctgcgtccta gagcgcgatg gctcgcggtc 780gtgcgtgtgt cgcgttggct gggccggcaa cgggatcctc tgtggtcgcg acactgacct 840agacggcttc ccggacgaga agctgcgctg cccggagccg cagtgccgta aggacaactg 900cgtgactgtg cccaactcag ggcaggagga tgtggaccgc gatggcatcg gagacgcctg 960cgatccggat gccgacgggg acggggtccc caatgaaaag gacaactgcc cgctggtgcg1020gaacccagac cagcgcaaca cggacgagga caagtggggc gatgcgtgcg acaactgccg1080gtcccagaag aacgacgacc aaaaggacac agaccaggac ggccggggcg atgcgtgcga1140cgacgacatc gacggcgacc ggatccgcaa ccaggccgac aactgcccta gggtacccaa1200ctcagaccag aaggacagtg atggcgatgg tataggggat gcctgtgaca actgtcccca1260gaagagcaac ccggatcagg cggatgtgga ccacgacttt gtgggagatg cttgtgacag1320cgatcaagac caggatggag acggacatca ggactctcgg gacaactgtc ccacggtgcc1380taacagtgcc caggaggact cagaccacga tggccagggt gatgcctgcg acgacgacga1440cgacaatgac ggagtccctg acagtcggga caactgccgc ctggtgccta accccggcca1500ggaggacgcg gacagggacg gcgtgggcga cgtgtgccag gacgactttg atgcagacaa1560ggtggtagac aagatcgacg tgtgtccgga gaacgctgaa gtcacgctca ccgacttcag1620ggccttccag acagtcgtgc tggacccgga gggtgacgcg cagattgacc ccaactgggt1680ggtgctcaac cagggaaggg agatcgtgca gacaatgaac agcgacccag gcctggctgt1740gggttacact gccttcaatg gcgtggactt cgagggcacg ttccatgtga acacggtcac1800ggatgacgac tatgcgggct tcatctttgg ctaccaggac agctccagct tctacgtggt1860catgtggaag cagatggagc aaacgtattg gcaggcgaac cccttccgtg ctgtggccga1920gcctggcatc caactcaagg ctgtgaagtc ttccacaggc cccggggaac agctgcggaa1980cgctctgtgg catacaggag acacagagtc ccaggtgcgg ctgctgtgga aggacccgcg2040aaacgtgggt tggaaggaca agaagtccta tcgttggttc ctgcagcacc ggccccaagt2100gggctacatc agggtgcgat tctatgaggg ccctgagctg gtggccgaca gcaacgtggt2160cttggacaca accatgcggg gtggccgcct gggggtcttc tgcttctccc aggagaacat2220catctgggcc aacctgcgtt accgctgcaa tgacaccatc ccagaggact atgagaccca2280tcagctgcgg caagcctagg gaccagggtg aggacccgcc ggatgacagc caccctcacc2340gcggctggat gggggctctg cacccagccc aaggggtggc cgtcctgagg gggaagtgag2400aagggctcag agaggacaaa ataaagtgtg tgtgcaggg 2439<210>43<211>1385<212>DNA<213>人<400>43ctccagccat tggtgtctgt gtcattacta atagagtctt gtaaacactc gttaatcacg 60gaagccgccg gcctggggct ccgcacgcca gcctgtgcgg gtcttccccg cctctgcagc120
ctagtgggaa ggaggtggga ggaaagaagg aagaaaggga gggagggagg aggcaggcca 180gagggaggga ccgcctcgga ggcagaagag ccgcgaggag ccagcggagc accgcgggct 240ggggcgcagc cacccgccgc tcctcgagtc ccctcgcccc tttcccttcg tgccccccgg 300cagcctccag cgtcggtccc caggcagcat ggtgaggtct gctcccggtc cctcgccacc 360atgtacgtga gctacctcct ggacaaggac gtgagcatgt accctagctc cgtgcgccac 420tctggcggcc tcaacctggc gccgcagaac ttcgtcagcc ccccgcagta cccggactac 480ggcggttacc acgtggcggc cgcagctgca gcggcagcga acttggacag cgcgcagtcc 540ccggggccat cctggccggc agcgtatggc gccccactcc gggaggactg gaatggctac 600gcgcccggag gcgccgcggc cgccgccaac gccgtggctc acggcctcaa cggtggctcc 660ccggccgcag ccatgggcta cagcagcccc gcagactacc atccgcacca ccacccgcat 720caccacccgc accacccggc cgcggcgcct tcctgcgctt ctgggctgct gcaaacgctc 780aaccccggcc ctcctgggcc cgccgccacc gctgccgccg agcagctgtc tcccggcggc 840cagcggcgga acctgtgcga gtggatgcgg aagccggcgc agcagtccct cggcagccaa 900gtgaaaacca ggacgaaaga caaatatcga gtggtgtaca cggaccacca gcggctggag 960ctggagaagg agtttcacta cagtcgctac atcaccatcc ggaggaaagc cgagctagcc1020gccacgctgg ggctctctga gaggcaggtt aaaatctggt ttcagaaccg cagagcaaag1080gagaggaaaa tcaacaagaa gaagttgcag cagcaacagc agcagcagcc accacagccg1140cctccgccgc caccacagcc tccccagcct cagccaggtc ctctgagaag tgtcccagag1200cccttgagtc cggtgtcttc cctgcaagcc tcagtgtctg gctctgtccc tggggttctg1260gggccaactg ggggggtgct aaaccccacc gtcacccagt gacccaccgg ggttctgcag1320cggcagagca attccaggct gagccatgag gagcgtggac tctgctagac tcctcaggag1380agacc1385<210>44<211>4098<212>DNA<213>人<400>44ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540
gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg1020gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca1080ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga1140tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat1200ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg1260gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg1320gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa1380tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag1440ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta1500ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt1560ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga1620ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa1680atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca1740ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc1800gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg1860cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc1920taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag1980gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat2040ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg2100ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca2160tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat2220atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc2280ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag2340taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt2400atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga2460cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa2520actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc2580atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg2640
gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc2700ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag2760gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc2820ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact2880tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc2940tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg3000gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca3060aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa3120ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc3180aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg3240tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca3300agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag3360accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata3420tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg3480aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa3540tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga3600cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta3660ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat3720ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga3780gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact3840tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat3900ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg3960ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc4020ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa4080agcgtgttaa ctttttgg 4098<210>45<211>4098<212>DNA<213>人<400>45ggtggcctct gtggccgtcc aggctagcgg cggcccgcag gcggcgggga gaaagactct 60ctcacctggt cttgcggctg tggccaccgc cggccagggg tgtggagggc gtgctgccgg 120agacgtccgc cgggctctgc agttccgccg ggggtcgggc agctatggag ccgcggccca 180cggcgccctc ctccggcgcc ccgggactgg ccggggtcgg ggagacgccg tcagccgctg 240cgctggccgc agccagggtg gaactgcccg gcacggctgt gccctcggtg ccggaggatg 300ctgcgcccgc gagccgggac ggcggcgggg tccgcgatga gggccccgcg gcggccgggg 360
acgggctggg cagacccttg gggcccaccc cgagccagag ccgtttccag gtggacctgg 420tttccgagaa cgccgggcgg gccgctgctg cggcggcggc ggcggcggcg gcagcggcgg 480cggctggtgc tggggcgggg gccaagcaga cccccgcgga cggggaagcc agcggcgaga 540gcgagccagc taaaggcagc gaggaagcca agggccgctt ccgcgtgaac ttcgtggacc 600cagctgcctc ctcgtcggct gaagacagcc tgtcagatgc tgccggggtc ggagtcgacg 660ggcccaacgt gagcttccag aacggcgggg acacggtgct gagcgagggc agcagcctgc 720actccggcgg cggcggcggc agtgggcacc accagcacta ctattatgat acccacacca 780acacctacta cctgcgcacc ttcggccaca acaccatgga cgctgtgccc aggatcgatc 840actaccggca cacagccgcg cagctgggcg agaagctgct ccggcctagc ctggcggagc 900tccacgacga gctggaaaag gaaccttttg aggatggctt tgcaaatggg gaagaaagta 960ctccaaccag agatgctgtg gtcacgtata ctgcagaaag taaaggagtc gtgaagtttg1020gctggatcaa gggtgtatta gtacgttgta tgttaaacat ttggggtgtg atgcttttca1080ttagattgtc atggattgtg ggtcaagctg gaataggtct atcagtcctt gtaataatga1140tggccactgt tgtgacaact atcacaggat tgtctacttc agcaatagca actaatggat1200ttgtaagagg aggaggagca tattatttaa tatctagaag tctagggcca gaatttggtg1260gtgcaattgg tctaatcttc gcctttgcca acgctgttgc agttgctatg tatgtggttg1320gatttgcaga aaccgtggtg gagttgctta aggaacattc catacttatg atagatgaaa1380tcaatgatat ccgaattatt ggagccatta cagtcgtgat tcttttaggt atctcagtag1440ctggaatgga gtgggaagca aaagctcaga ttgttctttt ggtgatccta cttcttgcta1500ttggtgattt cgtcatagga acatttatcc cactggagag caagaagcca aaagggtttt1560ttggttataa atctgaaata tttaatgaga actttgggcc cgattttcga gaggaagaga1620ctttcttttc tgtatttgcc atcttttttc ctgctgcaac tggtattctg gctggagcaa1680atatctcagg tgatcttgca gatcctcagt cagccatacc caaaggaaca ctcctagcca1740ttttaattac tacattggtt tacgtaggaa ttgcagtatc tgtaggttct tgtgttgttc1800gagatgccac tggaaacgtt aatgacacta tcgtaacaga gctaacaaac tgtacttctg1860cagcctgcaa attaaacttt gatttttcat cttgtgaaag cagtccttgt tcctatggcc1920taatgaacaa cttccaggta atgagtatgg tgtcaggatt tacaccacta atttctgcag1980gtatattttc agccactctt tcttcagcat tagcatccct agtgagtgct cccaaaatat2040ttcaggctct atgtaaggac aacatctacc cagctttcca gatgtttgct aaaggttatg2100ggaaaaataa tgaacctctt cgtggctaca tcttaacatt cttaattgca cttggattca2160tcttaattgc tgaactgaat gttattgcac caattatctc aaacttcttc cttgcatcat2220atgcattgat caatttttca gtattccatg catcacttgc aaaatctcca ggatggcgtc2280ctgcattcaa atactacaac atgtggatat cacttcttgg agcaattctt tgttgcatag2340taatgttcgt cattaactgg tgggctgcat tgctaacata tgtgatagtc cttgggctgt2400
atatttatgt tacctacaaa aaaccagatg tgaattgggg atcctctaca caagccctga 2460cttacctgaa tgcactgcag cattcaattc gtctttctgg agtggaagac cacgtgaaaa 2520actttaggcc acagtgtctt gttatgacag gtgctccaaa ctcacgtcca gctttacttc 2580atcttgttca tgatttcaca aaaaatgttg gtttgatgat ctgtggccat gtacatatgg 2640gtcctcgaag acaagccatg aaagagatgt ccatcgatca agccaaatat cagcgatggc 2700ttattaagaa caaaatgaag gcattttatg ctccagtaca tgcagatgac ttgagagaag 2760gtgcacagta tttgatgcag gctgctggtc ttggtcgtat gaagccaaac acacttgtcc 2820ttggatttaa gaaagattgg ttgcaagcag atatgaggga tgtggatatg tatataaact 2880tatttcatga tgcttttgac atacaatatg gagtagtggt tattcgccta aaagaaggtc 2940tggatatatc tcatcttcaa ggacaagaag aattattgtc atcacaagag aaatctcctg 3000gcaccaagga tgtggtagta agtgtggaat atagtaaaaa gtccgattta gatacttcca 3060aaccactcag tgaaaaacca attacacaca aagttgagga agaggatggc aagactgcaa 3120ctcaaccact gttgaaaaaa gaatccaaag gccctattgt gcctttaaat gtagctgacc 3180aaaagcttct tgaagctagt acacagtttc agaaaaaaca aggaaagaat actattgatg 3240tctggtggct ttttgatgat ggaggtttga ccttattgat accttacctt ctgacgacca 3300agaaaaaatg gaaagactgt aagatcagag tattcattgg tggaaagata aacagaatag 3360accatgaccg gagagcgatg gctactttgc ttagcaagtt ccggatagac ttttctgata 3420tcatggttct aggagatatc aataccaaac caaagaaaga aaatattata gcttttgagg 3480aaatcattga gccatacaga cttcatgaag atgataaaga gcaagatatt gcagataaaa 3540tgaaagaaga tgaaccatgg cgaataacag ataatgagct tgaactttat aagaccaaga 3600cataccggca gatcaggtta aatgagttat taaaggaaca ttcaagcaca gctaatatta 3660ttgtcatgag tctcccagtt gcacgaaaag gtgctgtgtc tagtgctctc tacatggcat 3720ggttagaagc tctatctaag gacctaccac caatcctcct agttcgtggg aatcatcaga 3780gtgtccttac cttctattca taaatgttct atacagtgga cagccctcca gaatggtact 3840tcagtgccta gtgtagtaac ctgaaatctt caatgacaca ttaacatcac aatggcgaat 3900ggtgactttt ctttcacgat ttcattaatt tgaaagcaca caggaaagct tgctccattg 3960ataacgtgta tggagacttc ggttttagtc aattccatat ctcaatctta atggtgattc 4020ttctctgttg aactgaagtt tgtgagagta gttttccttt gctacttgaa tagcaataaa 4080agcgtgttaa ctttttgg 4098<210>46<211>3311<212>DNA<213>人<400>46tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120
tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt1020gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt1080gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa1140aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag1200aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga1260caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc1320aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg1380gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac1440agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg1500tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat1560ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac1620gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa1680gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt1740cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct1800cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat1860ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca1920acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta1980gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact2040tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg2100tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa2160ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg2220
gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg2280gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca2340acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca2400gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag2460aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac2520aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca2580aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt2640cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga2700acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc2760aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa2820gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct2880attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct2940ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct3000tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg3060aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata3120aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc3180tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg3240ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac3300aactgggtaa a 3311<210>47<211>3311<212>DNA<213>人<400>47tgctaatgct tttggtacaa atggatgtgg aatataattg aatattttct tgtttaaggg 60gagcatgaag aggtgttgag gttatgtcaa gcatctggca cagctgaagg cagatggaaa 120tatttacaag tacgcaattt gagactaaga tattgttatc attctcctat tgaagacaag 180agcaatagta aaacacatca ggtcaggggg ttaaagacct gtgataaacc acttccgata 240agttggaaac gtgtgtctat attttcatat ctgtatatat ataatggtaa agaaagacac 300cttcgtaacc cgcattttcc aaagagagga atcacaggga gatgtacagc aatggggcca 360tttaagagtt ctgtgttcat cttgattctt caccttctag aaggggccct gagtaattca 420ctcattcagc tgaacaacaa tggctatgaa ggcattgtcg ttgcaatcga ccccaatgtg 480ccagaagatg aaacactcat tcaacaaata aaggacatgg tgacccaggc atctctgtat 540ctgtttgaag ctacaggaaa gcgattttat ttcaaaaatg ttgccatttt gattcctgaa 600acatggaaga caaaggctga ctatgtgaga ccaaaacttg agacctacaa aaatgctgat 660gttctggttg ctgagtctac tcctccaggt aatgatgaac cctacactga gcagatgggc 720
aactgtggag agaagggtga aaggatccac ctcactcctg atttcattgc aggaaaaaag 780ttagctgaat atggaccaca aggtaaggca tttgtccatg agtgggctca tctacgatgg 840ggagtatttg acgagtacaa taatgatgag aaattctact tatccaatgg aagaatacaa 900gcagtaagat gttcagcagg tattactggt acaaatgtag taaagaagtg tcagggaggc 960agctgttaca ccaaaagatg cacattcaat aaagttacag gactctatga aaaaggatgt1020gagtttgttc tccaatcccg ccagacggag aaggcttcta taatgtttgc acaacatgtt1080gattctatag ttgaattctg tacagaacaa aaccacaaca aagaagctcc aaacaagcaa1140aatcaaaaat gcaatctccg aagcacatgg gaagtgatcc gtgattctga ggactttaag1200aaaaccactc ctatgacaac acagccacca aatcccacct tctcattgct gcagattgga1260caaagaattg tgtgtttagt ccttgacaaa tctggaagca tggcgactgg taaccgcctc1320aatcgactga atcaagcagg ccagcttttc ctgctgcaga cagttgagct ggggtcctgg1380gttgggatgg tgacatttga cagtgctgcc catgtacaaa gtgaactcat acagataaac1440agtggcagtg acagggacac actcgccaaa agattacctg cagcagcttc aggagggacg1500tccatctgca gcgggcttcg atcggcattt actgtgatta ggaagaaata tccaactgat1560ggatctgaaa ttgtgctgct gacggatggg gaagacaaca ctataagtgg gtgctttaac1620gaggtcaaac aaagtggtgc catcatccac acagtcgctt tggggccctc tgcagctcaa1680gaactagagg agctgtccaa aatgacagga ggtttacaga catatgcttc agatcaagtt1740cagaacaatg gcctcattga tgcttttggg gccctttcat caggaaatgg agctgtctct1800cagcgctcca tccagcttga gagtaaggga ttaaccctcc agaacagcca gtggatgaat1860ggcacagtga tcgtggacag caccgtggga aaggacactt tgtttcttat cacctggaca1920acgcagcctc cccaaatcct tctctgggat cccagtggac agaagcaagg tggctttgta1980gtggacaaaa acaccaaaat ggcctacctc caaatcccag gcattgctaa ggttggcact2040tggaaataca gtctgcaagc aagctcacaa accttgaccc tgactgtcac gtcccgtgcg2100tccaatgcta ccctgcctcc aattacagtg acttccaaaa cgaacaagga caccagcaaa2160ttccccagcc ctctggtagt ttatgcaaat attcgccaag gagcctcccc aattctcagg2220gccagtgtca cagccctgat tgaatcagtg aatggaaaaa cagttacctt ggaactactg2280gataatggag caggtgctga tgctactaag gatgacggtg tctactcaag gtatttcaca2340acttatgaca cgaatggtag atacagtgta aaagtgcggg ctctgggagg agttaacgca2400gccagacgga gagtgatacc ccagcagagt ggagcactgt acatacctgg ctggattgag2460aatgatgaaa tacaatggaa tccaccaaga cctgaaatta ataaggatga tgttcaacac2520aagcaagtgt gtttcagcag aacatcctcg ggaggctcat ttgtggcttc tgatgtccca2580aatgctccca tacctgatct cttcccacct ggccaaatca ccgacctgaa ggcggaaatt2640cacgggggca gtctcattaa tctgacttgg acagctcctg gggatgatta tgaccatgga2700acagctcaca agtatatcat tcgaataagt acaagtattc ttgatctcag agacaagttc2760
aatgaatctc ttcaagtgaa tactactgct ctcatcccaa aggaagccaa ctctgaggaa2820gtctttttgt ttaaaccaga aaacattact tttgaaaatg gcacagatct tttcattgct2880attcaggctg ttgataaggt cgatctgaaa tcagaaatat ccaacattgc acgagtatct2940ttgtttattc ctccacagac tccgccagag acacctagtc ctgatgaaac gtctgctcct3000tgtcctaata ttcatatcaa cagcaccatt cctggcattc acattttaaa aattatgtgg3060aagtggatag gagaactgca gctgtcaata gcctagggct gaatttttgt cagataaata3120aaataaatca ttcatccttt ttttgattat aaaattttct aaaatgtatt ttagacttcc3180tgtagggggc gatatactaa atgtatatag tacatttata ctaaatgtat tcctgtaggg3240ggcgatatac taaatgtatt ttagacttcc tgtagggggc gataaaataa aatgctaaac3300aactgggtaa a 3311<210>48<211>3697<212>DNA<213>人<400>48agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga1020gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt1080tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt1140ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg1200acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg1260
attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct1320ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta1380acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt1440gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct1500gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca1560tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg1620ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat1680tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg1740tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg1800aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct1860ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat1920tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt1980agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca2040gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg2100aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc2160agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt2220ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa2280atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat2340gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta2400ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact2460gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt2520ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa2580agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa2640tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg2700tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc2760ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc2820tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc2880tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg2940gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg3000gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag3060acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta3120cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt3180tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt3240ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa3300catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc3360
ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac3420atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt3480caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc3540actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt3600ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca3660agaataaaca ctggttgtag tcagttttgt ttgttaa 3697<210>49<211>3697<212>DNA<213>人<400>49agggagtgtt cccgggggag atactccagt cgtagcaaga gtctcgacca ctgaatggaa 60gaaaaggact tttaaccacc attttgtgac ttacagaaag gaatttgaat aaagaaaact 120atgatacttc aggcccatct tcactccctg tgtcttctta tgctttattt ggcaactgga 180tatggccaag aggggaagtt tagtggaccc ctgaaaccca tgacattttc tatttatgaa 240ggccaagaac cgagtcaaat tatattccag tttaaggcca atcctcctgc tgtgactttt 300gaactaactg gggagacaga caacatattt gtgatagaac gggagggact tctgtattac 360aacagagcct tggacaggga aacaagatct actcacaatc tccaggttgc agccctggac 420gctaatggaa ttatagtgga gggtccagtc cctatcacca tagaagtgaa ggacatcaac 480gacaatcgac ccacgtttct ccagtcaaag tacgaaggct cagtaaggca gaactctcgc 540ccaggaaagc ccttcttgta tgtcaatgcc acagacctgg atgatccggc cactcccaat 600ggccagcttt attaccagat tgtcatccag cttcccatga tcaacaatgt catgtacttt 660cagatcaaca acaaaacggg agccatctct cttacccgag agggatctca ggaattgaat 720cctgctaaga atccttccta taatctggtg atctcagtga aggacatggg aggccagagt 780gagaattcct tcagtgatac cacatctgtg gatatcatag tgacagagaa tatttggaaa 840gcaccaaaac ctgtggagat ggtggaaaac tcaactgatc ctcaccccat caaaatcact 900caggtgcggt ggaatgatcc cggtgcacaa tattccttag ttgacaaaga gaagctgcca 960agattcccat tttcaattga ccaggaagga gatatttacg tgactcagcc cttggaccga1020gaagaaaagg atgcatatgt tttttatgca gttgcaaagg atgagtacgg aaaaccactt1080tcatatccgc tggaaattca tgtaaaagtt aaagatatta atgataatcc acctacatgt1140ccgtcaccag taaccgtatt tgaggtccag gagaatgaac gactgggtaa cagtatcggg1200acccttactg cacatgacag ggatgaagaa aatactgcca acagttttct aaactacagg1260attgtggagc aaactcccaa acttcccatg gatggactct tcctaatcca aacctatgct1320ggaatgttac agttagctaa acagtccttg aagaagcaag atactcctca gtacaactta1380acgatagagg tgtctgacaa agatttcaag accctttgtt ttgtgcaaat caacgttatt1440gatatcaatg atcagatccc catctttgaa aaatcagatt atggaaacct gactcttgct1500
gaagacacaa acattgggtc caccatctta accatccagg ccactgatgc tgatgagcca1560tttactggga gttctaaaat tctgtatcat atcataaagg gagacagtga gggacgcctg1620ggggttgaca cagatcccca taccaacacc ggatatgtca taattaaaaa gcctcttgat1680tttgaaacag cagctgtttc caacattgtg ttcaaagcag aaaatcctga gcctctagtg1740tttggtgtga agtacaatgc aagttctttt gccaagttca cgcttattgt gacagatgtg1800aatgaagcac ctcaattttc ccaacacgta ttccaagcga aagtcagtga ggatgtagct1860ataggcacta aagtgggcaa tgtgactgcc aaggatccag aaggtctgga cataagctat1920tcactgaggg gagacacaag aggttggctt aaaattgacc acgtgactgg tgagatcttt1980agtgtggctc cattggacag agaagccgga agtccatatc gggtacaagt ggtggccaca2040gaagtagggg ggtcttcctt gagctctgtg tcagagttcc acctgatcct tatggatgtg2100aatgacaacc ctcccaggct agccaaggac tacacgggct tgttcttctg ccatcccctc2160agtgcacctg gaagtctcat tttcgaggct actgatgatg atcagcactt atttcggggt2220ccccatttta cattttccct cggcagtgga agcttacaaa acgactggga agtttccaaa2280atcaatggta ctcatgcccg actgtctacc aggcacacag agtttgagga gagggagtat2340gtcgtcttga tccgcatcaa tgatgggggt cggccaccct tggaaggcat tgtttcttta2400ccagttacat tctgcagttg tgtggaagga agttgtttcc ggccagcagg tcaccagact2460gggataccca ctgtgggcat ggcagttggt atactgctga ccacccttct ggtgattggt2520ataattttag cagttgtgtt tatccgcata aagaaggata aaggcaaaga taatgttgaa2580agtgctcaag catctgaagt caaacctctg agaagctgaa tttgaaaagg aatgtttgaa2640tttatatagc aagtgctatt tcagcaacaa ccatctcatc ctattacttt tcatctaacg2700tgcattataa ttttttaaac agatattccc tcttgtcctt taatatttgc taaatatttc2760ttttttgagg tggagtcttg ctctgtcgcc caggctggag tacagtggtg tgatcccagc2820tcactgcaac ctccgcctcc tgggttcaca tgattctcct gcctcagctt cctaagtagc2880tgggtttaca ggcacccacc accatgccca gctaattttt gtatttttaa tagagacggg2940gtttcgccat ttggccaggc tggtcttgaa ctcctgacgt caagtgatct gcctgccttg3000gtctcccaat acaggcatga accactgcac ccacctactt agatatttca tgtgctatag3060acattagaga gatttttcat ttttccatga catttttcct ctctgcaaat ggcttagcta3120cttgtgtttt tcccttttgg ggcaagacag actcattaaa tattctgtac attttttctt3180tatcaaggag atatatcagt gttgtctcat agaactgcct ggattccatt tatgtttttt3240ctgattccat cctgtgtccc cttcatcctt gactcctttg gtatttcact gaatttcaaa3300catttgtcag agaagaaaaa cgtgaggact caggaaaaat aaataaataa aagaacagcc3360ttttccctta gtattaacag aaatgtttct gtgtcattaa ccatctttaa tcaatgtgac3420atgttgctct ttggctgaaa ttcttcaact tggaaatgac acagacccac agaaggtgtt3480caaacacaac ctactctgca aaccttggta aaggaaccag tcagctggcc agatttcctc3540
actacctgcc atgcatacat gctgcgcatg ttttcttcat tcgtatgtta gtaaagtttt 3600ggttattata tatttaacat gtggaagaaa acaagacatg aaaagagtgg tgacaaatca 3660agaataaaca ctggttgtag tcagttttgt ttgttaa 3697<210>50<211>3803<212>DNA<213>人<400>50ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct1020gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt1080gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga1140gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa1200ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac1260agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta1320caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg1380gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca1440agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat1500tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga1560gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag1620tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac1680
agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt1740gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca1800tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc1860caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa1920tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg1980catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg2040cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga2100cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct2160cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg2220gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct2280gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc2340cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga2400ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag2460ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa2520tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga2580ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac2640ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac2700agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac2760ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc2820ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc2880ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca2940ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg3000actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga3060gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga3120gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt3180tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc3240tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag3300cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc3360tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca3420gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc3480acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc3540cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga3600aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg3660cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag3720aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga3780
caattaaaat ctttattcca gtg3803<210>51<211>3803<212>DNA<213>人<400>51ccatggtagg agcgctcgcc tcgctgcggt gcccgctgag gccatgccgg ggccccggcg 60ccccgctggc tcccgcctgc gcctgctcct gctcctgctg ctgccgccgc tgctgctgct 120gctccggggc agccacgcgg gcaacctgac ggtagccgtg gtactgccgc tggccaatac 180ctcgtacccc tggtcgtggg cgcgcgtggg acccgccgtg gagctggccc tggcccaggt 240gaaggcgcgc cccgacttgc tgccgggctg gacggtccgc acggtgctgg gcagcagcga 300aaacgcgctg ggcgtctgct ccgacaccgc agcgcccctg gccgcggtgg acctcaagtg 360ggagcacaac cccgctgtgt tcctgggccc cggctgcgtg tacgccgccg ccccagtggg 420gcgcttcacc gcgcactggc gggtcccgct gctgaccgcc ggcgccccgg cgctgggctt 480cggtgtcaag gacgagtatg cgctgaccac ccgcgcgggg cccagctacg ccaagctggg 540ggacttcgtg gcggcgctgc accgacggct gggctgggag cgccaagcgc tcatgctcta 600cgcctaccgg ccgggtgacg aagagcactg cttcttcctc gtggaggggc tgttcatgcg 660ggtccgcgac cgcctcaata ttacggtgga ccacctggag ttcgccgagg acgacctcag 720ccactacacc aggctgctgc ggaccatgcc gcgcaaaggc cgagttatct acatctgcag 780ctcccctgat gccttcagaa ccctcatgct cctggccctg gaagctggct tgtgtgggga 840ggactacgtt ttcttccacc tggatatctt tgggcaaagc ctgcaaggtg gacagggccc 900tgctccccgc aggccctggg agagagggga tgggcaggat gtcagtgccc gccaggcctt 960tcaggctgcc aaaatcatta catataaaga cccagataat cccgagtact tggaattcct1020gaagcagtta aaacacctgg cctatgagca gttcaacttc accatggagg atggcctggt1080gaacaccatc ccagcatcct tccacgacgg gctcctgctc tatatccagg cagtgacgga1140gactctggca catgggggaa ctgttactga tggggagaac atcactcagc ggatgtggaa1200ccgaagcttt caaggtgtga caggatacct gaaaattgat agcagtggcg atcgggaaac1260agacttctcc ctctgggata tggatcccga gaatggtgcc ttcagggttg tactgaacta1320caatgggact tcccaagagc tggtggctgt gtcggggcgc aaactgaact ggcccctggg1380gtaccctcct cctgacatcc ccaaatgtgg ctttgacaac gaagacccag catgcaacca1440agatcacctt tccaccctgg aggtgctggc tttggtgggc agcctctcct tgctcggcat1500tctgattgtc tccttcttca tatacaggaa gatgcagctg gagaaggaac tggcctcgga1560gctgtggcgg gtgcgctggg aggacgttga gcccagtagc cttgagaggc acctgcggag1620tgcaggcagc cggctgaccc tgagcgggag aggctccaat tacggctccc tgctaaccac1680agagggccag ttccaagtct ttgccaagac agcatattat aagggcaacc tcgtggctgt1740gaaacgtgtg aaccgtaaac gcattgagct gacacgaaaa gtcctgtttg aactgaagca1800
tatgcgggat gtgcagaatg aacacctgac caggtttgtg ggagcctgca ccgacccccc1860caatatctgc atcctcacag agtactgtcc ccgtgggagc ctgcaggaca ttctggagaa1920tgagagcatc accctggact ggatgttccg gtactcactc accaatgaca tcgtcaaggg1980catgctgttt ctacacaatg gggctatctg ttcccatggg aacctcaagt catccaactg2040cgtggtagat gggcgctttg tgctcaagat caccgactat gggctggaga gcttcaggga2100cctggaccca gagcaaggac acaccgttta tgccaaaaag ctgtggacgg cccctgagct2160cctgcgaatg gcttcacccc ctgtgcgggg ctcccaggct ggtgacgtat acagctttgg2220gatcatcctt caggagattg ccctgaggag tggggtcttc cacgtggaag gtttggacct2280gagccccaaa gagatcatcg agcgggtgac tcggggtgag cagcccccct tccggccctc2340cctggccctg cagagtcacc tggaggagtt ggggctgctc atgcagcggt gctgggctga2400ggacccacag gagaggccac cattccagca gatccgcctg acgttgcgca aatttaacag2460ggagaacagc agcaacatcc tggacaacct gctgtcccgc atggagcagt acgcgaacaa2520tctggaggaa ctggtggagg agcggaccca ggcatacctg gaggagaagc gcaaggctga2580ggccctgctc taccagatcc tgcctcactc agtggctgag cagctgaagc gtggggagac2640ggtgcaggcc gaagcctttg acagtgttac catctacttc agtgacattg tgggtttcac2700agcgctgtcg gcggagagca cacccatgca ggtggtgacc ctgctcaatg acctgtacac2760ttgctttgat gctgtcatag acaactttga tgtgtacaag gtggagacaa ttggcgatgc2820ctacatggtg gtgtcagggc tccctgtgcg gaacgggcgg ctacacgcct gcgaggtagc2880ccgcatggcc ctggcactgc tggatgctgt gcgctccttc cgaatccgcc accggcccca2940ggagcagctg cgcttgcgca ttggcatcca cacaggacct gtgtgtgctg gagtggtggg3000actgaagatg ccccgttact gtctctttgg ggatacagtc aacacagcct caagaatgga3060gtctaatggg gaagccctga agatccactt gtcttctgag accaaggctg tcctggagga3120gtttggtggt ttcgagctgg agcttcgagg ggatgtagaa atgaagggca aaggcaaggt3180tcggacctac tggctccttg gggagagggg gagtagcacc cgaggctgac ctgcctcctc3240tcctatccct ccacacctcc cctaccctgt gccagaagca acagaggtgc caggcctcag3300cctcacccac agcagcccca tcgccaaagg atggaagtaa tttgaatagc tcaggtgtgc3360tgaccccagt gaagacacca gataggacct ctgagagggg actggcatgg ggggatctca3420gagcttacag gctgagccaa gcccacggcc atgcacaggg acactcacac aggcacacgc3480acctgctctc cacctggact caggccgggc tgggctgtgg atccttgatc ccctcccctc3540cccatgctct cctccctcag ccttgctacc ctgtgactta ctgggaggag agtcacctga3600aggggaacat gaaaagagac taggtgaaga gagggcaggg gagcccacat ctggggctgg3660cccacaatac ctgctccccc gaccccctcc acccagcagt agacacagtg cacaggggag3720aagaggggtg gcgcagaagg gttgggggcc tgtatgcctt gcttctacca tgagcagaga3780caattaaaat ctttattcca gtg3803
<210>52<211>1155<212>DNA<213>人<400>52atggattgca gtaacggatc ggcagagtgt accggagaag gaggatcaaa agaggtggtg 60gggactttta aggctaaaga cctaatagtc acaccagcta ccattttaaa ggaaaaacca 120gaccccaata atctggtttt tggaactgtg ttcacggatc atatgctgac ggtggagtgg 180tcctcagagt ttggatggga gaaacctcat atcaagcctc ttcagaacct gtcattgcac 240cctggctcat cagctttgca ctatgcagtg gaattatttg aaggattgaa ggcatttcga 300ggagtagata ataaaattcg actgtttcag ccaaacctca acatggatag aatgtatcgc 360tctgctgtga gggcaactct gccggtattt gacaaagaag agctcttaga gtgtattcaa 420cagcttgtga aattggatca agaatgggtc ccatattcaa catctgctag tctgtatatt 480cgtcctgcat tcattggaac tgagccttct cttggagtca agaagcctac caaagccctg 540ctctttgtac tcttgagccc agtgggacct tatttttcaa gtggaacctt taatccagtg 600tccctgtggg ccaatcccaa gtatgtaaga gcctggaaag gtggaactgg ggactgcaag 660atgggaggga attacggctc atctcttttt gcccaatgtg aagacgtaga taatgggtgt 720cagcaggtcc tgtggctcta tggcagagac catcagatca ctgaagtggg aactatgaat 780ctttttcttt actggataaa tgaagatgga gaagaagaac tggcaactcc tccactagat 840ggcatcattc ttccaggagt gacaaggcgg tgcattctgg acctggcaca tcagtggggt 900gaatttaagg tgtcagagag atacctcacc atggatgact tgacaacagc cctggagggg 960aacagagtga gagagatgtt tagctctggt acagcctgtg ttgtttgccc agtttctgat1020atactgtaca aaggcgagac aatacacatt ccaactatgg agaatggtcc taagctggca1080agccgcatct tgagcaaatt aactgatatc cagtatggaa gagaagagag cgactggaca1140attgtgctat cctga 1155<210>53<211>2511<212>DNA<213>人<400>53cttttcacac tggccttaaa gaggatatat tagaagttga agtaggaagg gagccagaga 60ggccgatggc gcaaaggtac gacgatctac cccattacgg gggcatggat ggagtaggca 120tcccctccac gatgtatggg gacccgcatg cagccaggtc catgcagccg gtccaccacc 180tgaaccacgg gcctcctctg cactcgcatc agtacccgca cacagctcat accaacgcca 240tggcccccag catgggctcc tctgtcaatg acgctttaaa gagagataaa gatgccattt 300atggacaccc cctcttccct ctcttagcac tgatttttga gaaatgtgaa ttagctactt 360gtaccccccg cgagccgggg gtggcgggcg gggacgtctg ctcgtcagag tcattcaatg 420aagatatagc cgtgttcgcc aaacagattc gcgcagaaaa acctctattt tcttctaatc 480
cagaactgga taacttgatg attcaagcca tacaagtatt aaggtttcat ctattggaat 540tagagaaggt acacgaatta tgtgacaatt tctgccaccg gtatattagc tgtttgaaag 600ggaaaatgcc tatcgatttg gtgatagacg atagagaagg aggatcaaaa tcagacagtg 660aagatataac aagatcagca aatctaactg accagccctc ttggaacaga gatcatgatg 720acacggcatc tactcgttca ggaggaaccc caggcccttc cagcggtggc cacacgtcac 780acagtgggga caacagcagt gagcaaggtg atggcttgga caacagtgta gcttccccca 840gcacaggtga cgatgatgac cctgataagg acaaaaagcg tcacaaaaag cgtggcatct 900ttcccaaagt agccacaaat atcatgaggg cgtggctgtt ccagcatcta acacaccctt 960acccttctga agaacagaaa aagcagttgg cacaagacac gggactcacc atccttcaag1020tgaacaattg gtttattaat gcccggagaa gaatagtgca gcccatgata gaccagtcca1080accgagcagt aagtcaagga acaccttata atcctgatgg acagcccatg ggaggtttcg1140taatggacgg tcagcaacat atgggaatta gagcaccagg acctatgagt ggaatgggca1200tgaatatggg catggagggg cagtggcact acatgtaacc ttcatctagt taaccaatcg1260caaagcaagg gggaaggctg caaagtatgc caggggagta tgtagcccgg ggtggtccaa1320tgggtgtgag tatgggacag ccaagttata cccaacccca gatgcccccc catcctgctc1380agctgcgtca tgggcccccc atgcatacgt acattcctgg acaccctcac cacccaacag1440tgatgatgca tggaggaccg ccccaccctg gaatgccaat gtcagcatca agccccacag1500ttcttaatac aggagaccca acaatgagtg gacaagtcat ggacattcat gctcagtagc1560ttaagggaat atgcattgtc tgcaatggtg actgatttca aatcatgttt tttctgcaat1620gactgtggag ttccattctt ggcatctact ctggaccaag gagcatccct aattcttcat1680agggaccttt aaaaagcagg aaataccaac tgaagtcaat ttgggggaca tgctaaataa1740ctatataaga cattaagaga acaaagagtg aaatattgta aatgctatta tactgttatc1800catattacgt tgtttcttat agatttttta aaaaaaatgt gaaatttttc cacactatgt1860gtgttgtttc catagctctt cacttcctcc agaagcctcc ttacattaaa aagccttaca1920gttatcctgc aagggacagg aaggtctgat ttgcaggatt tttagagcat taaaataact1980atcaggcaga agaatctttc ttctcgccta ggatttcagc catgcgcgcg ctctctctct2040ttctctctct tttcctctct ctccctcttt ctagcctggg gcttgaattt gcatgtctaa2100ttcatttact caccatattt gaattggcct gaacagatgt aaatcgggaa ggatgggaaa2160aactgcagtc atcaacaatg attaatcagc tgttgcaggc agtgtcttaa ggagactggt2220aggaggaggc atggaaacca aaaggccgtg tgtttagaag cctaattgtc acatcaagca2280tcattgtccc catgcaacaa ccaccacctt atacatcact tcctgtttta agcagctcta2340aaacatagac tgaagattta tttttaatat gttgacttta tttctgagca aagcatcggt2400catgtgtgta ttttttcata gtcccacctt ggagcattta tgtagacatt gtaaataaat2460tttgtgcaaa aaggactgga aaaatgaact gtattattgc aatttttttt t 2511
<210>54<211>1887<212>DNA<213>人<400>54tcgcccaatt ccgggctcag acactgggct cccagctggg gactgctcca tggccatgga 60gatagacagc aggcctgggg ggctccccgg cagtagctgc aacctaggtg cagcccgaga 120acacatgcag gcggtcaccc gaaactacat cacccacccc cgtgtcacct acaggactgt 180gtgcagcgtg aacgggcccc tggtggtgct ggaccgggtc aagtttgccc agtatgcgga 240gatcgtccac ttcaccctcc cagatgggac tcagaggagc gggcaggtgc ttgaggtggc 300tggcaccaag gcgattgttc aggtgtttga agggacatca gggatcgatg ccaggaagac 360cacttgcgaa tttacagggg acatcctacg aactccggtg tcagaggaca tgctgggtcg 420ggttttcaat ggctccggca agcccattga caaggggcca gtggtcatgg cggaggactt 480tctggatatc aatggccagc ccatcaaccc gcactcccgc atctaccccg aggagatgat 540tcagacgggc atttctccta ttgacgtcat gaacagcatt gcccgcggcc agaagatccc 600catcttctca gcagccgggc tcccccacaa tgagattgcc gctcagatct gccgccaggc 660ggggctggtg aagaagtcca aggctgtgct ggattaccat gacgacaact tcgccatcgt 720ctttgcagcc atgggggtga acatggagac agccagattc ttcaagtctg actttgagca 780gaatggaacc atggggaacg tctgcctctt cctgaacttg gccaatgacc ccacgatcga 840gcggatcatc accccgcgcc tggcgctgac cactgctgaa ttccttgcct accagtgtga 900gaagcatgtg ctggtcatac tgacggacat gagttcctat gcagaggcct tgcgggaggt 960ctctgctgct agagaggagg tgcctgggcg ccgagggttt cctggatata tgtacacaga1020cctggccacc atctacgagc gggcgggccg tgtggagggt cggggaggat ccatcacaca1080gatccccatc ctcaccatgc ccaacgacga tatcacccac cctatcccag acttgacggg1140cttcatcaca gagggacaga tctacgtgga cagacagctt cacaacagac agatctaccc1200ccccatcaac gtgctccctt ccctgtcgcg gctgatgaag tcagccattg gggaaggcat1260gacaagaaag gaccatggag atgtctccaa ccagctgtac gcctgctatg ccatcgggaa1320ggacgtgcag gccatgaagg cagtagttgg ggaggaggcg ctcacctctg aggacctgct1380ctacctggaa ttcctgcaga agtttgagaa gaacttcatc aatcagggcc cctacgagaa1440ccgctcgatg ttcgagtcgc tggaccttag ctggaagctg ctgcgcatct tccccaagga1500gatgctgaag cgcattccgc aggccgtgat cgacgagttc tattcccgcg aggggcggct1560gcaggacctc gcgcctgaca ctgcgctcta gccccgcgcg ccgtggcacc ccaacaccgg1620caggaaccta ccctcggctc ccgggtctcc ccgtccctcg ccacccctaa ccagcggctt1680tcgcgccgcc ctccgccctc cgtggctccg aggtggtggg gggcgccgca gtcatccctt1740tcctcgctcg attccttttc ccgcgctcca tgcctccccc tcagctcccg gtgctgcgga1800agaactgaag gttcatgcct actctgacgg gagcatctgt attttttatg ttaaaagccc1860
acaaaataaa aataaaaatg aactgag1887<210>55<211>1506<212>DNA<213>人<400>55aggcggacaa agcccgattg ttcctgggcc ctttccccat cgcgcctggg cctgctcccc 60agcccggggc aggggcgggg gccagtgtgg tgacacacgc tgtagctgtc tccccggctg 120gctggctcgc tctctcctgg ggacacagag gtcggcaggc agcacacaga gggacctacg 180ggcagctgtt ccttcccccg actcaagaat ccccggaggc ccggaggcct gcagcaggag 240cggccatgaa gaagctgatg gtggtgctga gtctgattgc tgcagcctgg gcagaggagc 300agaataagtt ggtgcatggc ggaccctgcg acaagacatc tcacccctac caagctgccc 360tctacacctc gggccacttg ctctgtggtg gggtccttat ccatccactg tgggtcctca 420cagctgccca ctgcaaaaaa ccgaatcttc aggtcttcct ggggaagcat aaccttcggc 480aaagggagag ttcccaggag cagagttctg ttgtccgggc tgtgatccac cctgactatg 540atgccgccag ccatgaccag gacatcatgc tgttgcgcct ggcacgccca gccaaactct 600ctgaactcat ccagcccctt cccctggaga gggactgctc agccaacacc accagctgcc 660acatcctggg ctggggcaag acagcagatg gtgatttccc tgacaccatc cagtgtgcat 720acatccacct ggtgtcccgt gaggagtgtg agcatgccta ccctggccag atcacccaga 780acatgttgtg tgctggggat gagaagtacg ggaaggattc ctgccagggt gattctgggg 840gtccgctggt atgtggagac cacctccgag gccttgtgtc atggggtaac atcccctgtg 900gatcaaagga gaagccagga gtctacacca acgtctgcag atacacgaac tggatccaaa 960aaaccattca ggccaagtga ccctgacatg tgacatctac ctcccgacct accaccccac1020tggctggttc cagaacgtct ctcacctaga ccttgcctcc cctcctctcc tgcccagctc1080tgaccctgat gcttaataaa cgcagcgacg tgagggtcct gattctccct ggttttaccc1140cagctccatc cttgcatcac tggggaggac gtgatgagtg aggacttggg tcctcggtct1200tacccccacc actaagagaa tacaggaaaa tcccttctag gcatctcctc tccccaaccc1260ttccacacgt ttgatttctt cctgcagagg cccagccacg tgtctggaat cccagctccg1320ctgcttactg tcggtgtccc cttgggatgt acctttcttc actgcagatt tctcacctgt1380aagatgaaga taaggatgat acagtctcca tcaggcagtg gctgttggaa agatttaaga1440tttcacacct atgacataca tgggatagca cctgggccgc catgcactca ataaagaatg1500tatttt 1506<210>56<211>2907<212>DNA<213>人<400>56gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc60
ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc 120tcctgcccga cacctggggg cgggcacctc aatgggtacc cggtgcctcc ctacgccttc 180ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac 240cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc 300agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag 360ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag 420ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg 480gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag 540aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag 600aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag 660ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc 720aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac 780aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg 840cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg 900gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc 960tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc1020gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg1080gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac1140cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg1200aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc1260atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg1320ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag1380ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc1440agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg1500ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg1560tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg1620ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact1680gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc1740tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc1800cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac1860tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac1920agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca1980ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata2040agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc2100
tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac 2160tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt 2220ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga 2280gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc 2340cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca 2400gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc 2460tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg 2520ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca 2580ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg 2640acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc 2700cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc 2760ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc 2820ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg 2880gataaagaat aaagttctat ttattct 2907<210>57<211>2907<212>DNA<213>人<400>57gccatctggg cccaggcccc atgccccgag gaggggtggt ctgaagccca ccagagcccc 60ctgccagact gtctgcctcc cttctgactg tggccgcttg gcatggccag caacagcagc120tcctgcccga cacctggg9g cgggcacctc aatgggtacc cggtgcctcc ctacgccttc180ttcttccccc ctatgctggg tggactctcc ccgccaggcg ctctgaccac tctccagcac240cagcttccag ttagtggata tagcacacca tccccagcca ccattgagac ccagagcagc300agttctgaag agatagtgcc cagccctccc tcgccacccc ctctaccccg catctacaag360ccttgctttg tctgtcagga caagtcctca ggctaccact atggggtcag cgcctgtgag420ggctgcaagg gcttcttccg ccgcagcatc cagaagaaca tggtgtacac gtgtcaccgg480gacaagaact gcatcatcaa caaggtgacc cggaaccgct gccagtactg ccgactgcag540aagtgctttg aagtgggcat gtccaaggag tctgtgagaa acgaccgaaa caagaagaag600aaggaggtgc ccaagcccga gtgctctgag agctacacgc tgacgccgga ggtgggggag660ctcattgaga aggtgcgcaa agcgcaccag gaaaccttcc ctgccctctg ccagctgggc720aaatacacta cgaacaacag ctcagaacaa cgtgtctctc tggacattga cctctgggac780aagttcagtg aactctccac caagtgcatc attaagactg tggagttcgc caagcagctg840cccggcttca ccaccctcac catcgccgac cagatcaccc tcctcaaggc tgcctgcctg900gacatcctga tcctgcggat ctgcacgcgg tacacgcccg agcaggacac catgaccttc960tcggacgggc tgaccctgaa ccggacccag atgcacaacg ctggcttcgg ccccctcacc 1020
gacctggtct ttgccttcgc caaccagctg ctgcccctgg agatggatga tgcggagacg1080gggctgctca gcgccatctg cctcatctgc ggagaccgcc aggacctgga gcagccggac1140cgggtggaca tgctgcagga gccgctgctg gaggcgctaa aggtctacgt gcggaagcgg1200aggcccagcc gcccccacat gttccccaag atgctaatga agattactga cctgcgaagc1260atcagcgcca agggggctga gcgggtgatc acgctgaaga tggagatccc gggctccatg1320ccgcctctca tccaggaaat gttggagaac tcagagggcc tggacactct gagcggacag1380ccggggggtg gggggcggga cgggggtggc ctggcccccc cgccaggcag ctgtagcccc1440agcctcagcc ccagctccaa cagaagcagc ccggccaccc actccccgtg accgcccacg1500ccacatggac acagccctcg ccctccgccc cggcttttct ctgcctttct accgaccatg1560tgaccccgca ccagccctgc ccccacctgc cctcccgggc agtactgggg accttccctg1620ggggacgggg agggaggagg cagcgactcc ttggacagag gcctgggccc tcagtggact1680gcctgctccc acagcctggg ctgacgtcag aggccgaggc caggaactga gtgaggcccc1740tggtcctggg tctcaggatg ggtcctgggg gcctcgtgtt catcaagaca cccctctgcc1800cagctcacca catcttcatc accagcaaac gccaggactt ggctccccca tcctcagaac1860tcacaagcca ttgctcccca gctggggaac ctcaacctcc cccctgcctc ggttggtgac1920agagggggtg ggacaggggc ggggggttcc ccctgtacat accctgccat accaacccca1980ggtattaatt ctcgctggtt ttgtttttat tttaattttt ttgttttgat ttttttaata2040agaattttca ttttaagcac atttatactg aaggaatttg tgctgtgtat tggggggagc2100tggatccaga gctggagggg gtgggtccgg gggagggagt ggctcggaag gggcccccac2160tctcctttca tgtccctgtg ccccccagtt ctcctcctca gccttttcct cctcagtttt2220ctctttaaaa ctgtgaagta ctaactttcc aaggcctgcc ttcccctccc tcccactgga2280gaagccgcca gcccctttct ccctctgcct gaccactggg tgtggacggt gtggggcagc2340cctgaaagga caggctcctg gccttggcac ttgcctgcac ccaccatgag gcatggagca2400gggcagagca agggccccgg gacagagttt tcccagacct ggctcctcgg cagagctgcc2460tcccgtcagg gcccacatca tctaggctcc ccagccccca ctgtgaaggg gctggccagg2520ggcccgagct gcccccaccc ccggcctcag ccaccagcac ccccataggg cccccagaca2580ccacacacat gcgcgtgcgc acacacacaa acacacacac actggacagt agatgggccg2640acacacactt ggcccgagtt cctccatttc cctggcctgc cccccacccc caacctgtcc2700cacccccgtg ccccctcctt accccgcagg acgggcctac aggggggtct cccctcaccc2760ctgcaccccc agctggggga gctggctctg ccccgacctc cttcaccagg ggttggggcc2820ccttcccctg gagcccgtgg gtgcacctgt tactgttggg ctttccactg agatctactg2880gataaagaat aaagttctat ttattct2907<210>58<211>5026<212>DNA<213>人
<400>58agaggaggaa attgttcctc gtctgataag acaacagtgg agaaaggacg catgctgttt 60cttagggaca cggctgactt ccagatatga ccatgtattt gtggcttaaa ctcttggcat 120ttggctttgc ctttctggac acagaagtat ttgtgacagg gcaaagccca acaccttccc 180ccactggatt gactacagca aagatgccca gtgttccact ttcaagtgac cccttaccta 240ctcacaccac tgcattctca cccgcaagca cctttgaaag agaaaatgac ttctcagaga 300ccacaacttc tcttagtcca gacaatactt ccacccaagt atccccggac tctttggata 360atgctagtgc ttttaatacc acaggtgttt catcagtaca gacgcctcac cttcccacgc 420acgcagactc gcagacgccc tctgctggaa ctgacacgca gacattcagc ggctccgccg 480ccaatgcaaa actcaaccct accccaggca gcaatgctat ctcagatgtc ccaggagaga 540ggagtacagc cagcaccttt cctacagacc cagtttcccc attgacaacc accctcagcc 600ttgcacacca cagctctgct gccttacctg cacgcacctc caacaccacc atcacagcga 660acacctcaga tgcctacctt aatgcctctg aaacaaccac tctgagccct tctggaagcg 720ctgtcatttc aaccacaaca atagctacta ctccatctaa gccaacatgt gatgaaaaat 780atgcaaacat cactgtggat tacttatata acaaggaaac taaattattt acagcaaagc 840taaatgttaa tgagaatgtg gaatgtggaa acaatacttg cacaaacaat gaggtgcata 900accttacaga atgtaaaaat gcgtctgttt ccatatctca taattcatgt actgctcctg 960ataagacatt aatattagat gtgccaccag gggttgaaaa gtttcagtta catgattgta1020cacaagttga aaaagcagat actactattt gtttaaaatg gaaaaatatt gaaaccttta1080cttgtgatac acagaatatt acctacagat ttcagtgtgg taatatgata tttgataata1140aagaaattaa attagaaaac cttgaacccg aacatgagta taagtgtgac tcagaaatac1200tctataataa ccacaagttt actaacgcaa gtaaaattat taaaacagat tttgggagtc1260caggagagcc tcagattatt ttttgtagaa gtgaagctgc acatcaagga gtaattacct1320ggaatccccc tcaaagatca tttcataatt ttaccctctg ttatataaaa gagacagaaa1380aagattgcct caatctggat aaaaacctga tcaaatatga tttgcaaaat ttaaaacctt1440atacgaaata tgttttatca ttacatgcct acatcattgc aaaagtgcaa cgtaatggaa1500gtgctgcaat gtgtcatttc acaactaaaa gtgctcctcc aagccaggtc tggaacatga1560ctgtctccat gacatcagat aatagtatgc atgtcaagtg taggcctccc agggaccgta1620atggccccca tgaacgttac catttggaag ttgaagctgg aaatactctg gttagaaatg1680agtcgcataa gaattgcgat ttccgtgtaa aagatcttca atattcaaca gactacactt1740ttaaggccta ttttcacaat ggagactatc ctggagaacc ctttatttta catcattcaa1800catcttataa ttctaaggca ctgatagcat ttctggcatt tctgattatt gtgacatcaa1860tagccctgct tgttgttctc tacaaaatct atgatctaca taagaaaaga tcctgcaatt1920tagatgaaca gcaggagctt gttgaaaggg atgatgaaaa acaactgatg aatgtggagc1980caatccatgc agatattttg ttggaaactt ataagaggaa gattgctgat gaaggaagac2040
tttttctggc tgaatttcag agcatcccgc gggtgttcag caagtttcct ataaaggaag 2100ctcgaaagcc ctttaaccag aataaaaacc gttatgttga cattcttcct tatgattata 2160accgtgttga actctctgag ataaacggag atgcagggtc aaactacata aatgccagct 2220atattgatgg tttcaaagaa cccaggaaat acattgctgc acaaggtccc agggatgaaa 2280ctgttgatga tttctggagg atgatttggg aacagaaagc cacagttatt gtcatggtca 2340ctcgatgtga agaaggaaac aggaacaagt gtgcagaata ctggccgtca atggaagagg 2400gcactcgggc ttttggagat gttgttgtaa agatcaacca gcacaaaaga tgtccagatt 2460acatcattca gaaattgaac attgtaaata aaaaagaaaa agcaactgga agagaggtga 2520ctcacattca gttcaccagc tggccagacc acggggtgcc tgaggatcct cacttgctcc 2580tcaaactgag aaggagagtg aatgccttca gcaatttctt cagtggtccc attgtggtgc 2640actgcagtgc tggtgttggg cgcacaggaa cctatatcgg aattgatgcc atgctagaag 2700gcctggaagc cgagaacaaa gtggatgttt atggttatgt tgtcaagcta aggcgacaga 2760gatgcctgat ggttcaagta gaggcccagt acatcttgat ccatcaggct ttggtggaat 2820acaatcagtt tggagaaaca gaagtgaatt tgtctgaatt acatccatat ctacataaca 2880tgaagaaaag ggatccaccc agtgagccgt ctccactaga ggctgaattc cagagacttc 2940cttcatatag gagctggagg acacagcaca ttggaaatca agaagaaaat aaaagtaaaa 3000acaggaattc taatgtcatc ccatatgact ataacagagt gccacttaaa catgagctgg 3060aaatgagtaa agagagtgag catgattcag atgaatcctc tgatgatgac agtgattcag 3120aggaaccaag caaatacatc aatgcatctt ttataatgag ctactggaaa cctgaagtga 3180tgattgctgc tcagggacca ctgaaggaga ccattggtga cttttggcag atgatcttcc 3240aaagaaaagt caaagttatt gttatgctga cagaactgaa acatggagac caggaaatct 3300gtgctcagta ctggggagaa ggaaagcaaa catatggaga tattgaagtt gacctgaaag 3360acacagacaa atcttcaact tatacccttc gtgtctttga actgagacat tccaagagga 3420aagactctcg aactgtgtac cagtaccaat atacaaactg gagtgtggag cagcttcctg 3480cagaacccaa ggaattaatc tctatgattc aggtcgtcaa acaaaaactt ccccagaaga 3540attcctctga agggaacaag catcacaaga gtacacctct actcattcac tgcagggatg 3600gatctcagca aacgggaata ttttgtgctt tgttaaatct cttagaaagt gcggaaacag 3660aagaggtagt ggatattttt caagtggtaa aagctctacg caaagctagg ccaggcatgg 3720tttccacatt cgagcaatat caattcctat atgacgtcat tgccagcacc taccctgctc 3780agaatggaca agtaaagaaa aacaaccatc aagaagataa aattgaattt gataatgaag 3840tggacaaagt aaagcaggat gctaattgtg ttaatccact tggtgcccca gaaaagctcc 3900ctgaagcaaa ggaacaggct gaaggttctg aacccacgag tggcactgag gggccagaac 3960attctgtcaa tggtcctgca agtccagctt taaatcaagg ttcataggaa aagacataaa 4020tgaggaaact ccaaacctcc tgttagctgt tatttctatt tttgtagaag taggaagtga 4080
aaataggtat acagtggatt aattaaatgc agcgaaccaa tatttgtaga agggttatat4140tttactactg tggaaaaata tttaagatag ttttgccaga acagtttgta cagacgtatg4200cttattttaa aattttatct cttattcagt aaaaaacaac ttctttgtaa tcgttatgtg4260tgtatatgta tgtgtgtatg ggtgtgtgtt tgtgtgagag acagagaaag agagagaatt4320ctttcaagtg aatctaaaag cttttgcttt tcctttgttt ttatgaagaa aaaatacatt4380ttatattaga agtgttaact tagcttgaag gatctgtttt taaaaatcat aaactgtgtg4440cagactcaat aaaatcatgt acatttctga aatgacctca agatgtcctc cttgttctac4500tcatatatat ctatcttata tacttactat tttacttcta gagatagtac ataaaggtgg4560tatgtgtgtg tatgctacta caaaaaagtt gttaactaaa ttaacattgg gaaatcttat4620attccatata ttagcattta gtccaatgtc tttttaagct tatttaatta aaaaatttcc4680agtgagctta tcatgctgtc tttacatggg gttttcaatt ttgcatgctc gattattccc4740tgtacaatat ttaaaattta ttgcttgata cttttgacaa caaattaggt tttgtacaat4800tgaacttaaa taaatgtcat taaaataaat aaatgcaata tgtattaata ttcattgtat4860aaaaatagaa gaatacaaac atatttgtta aatatttaca tatgaaattt aatatagcta4920tttttatgga atttttcatt gatatgaaaa atatgatatt gcatatgcat agttcccatg4980ttaaatccca ttcataactt tcattaaagc atttactttg aatttc 5026<210>59<211>624<212>DNA<213>人<400>59ggcgggccgc tcccacttcg gcacgagggg cacgaggtaa atcttttctg cttactgaaa 60aggaagagtc tgatgattag ttactgatcc tctttgcatt tgtaaagctt tggagatatt120gaatcatgtt accatttctg tttttttcca ccctgttttc ttccatattt actgaagctc180agaagcagta ttgggtctgc aactcatccg atgcaagtat ttcatacacc tactgtgata240aaatgcaata cccaatttca attaatgtta acccctgtat agaattgaaa ggatccaaag300gattattgca cattttctac attccaagga gagatttaaa gcaattatat ttcaatctct360atataactgt caacaccatg aatcttccaa agcgcaaaga agttatttgc cgaggatctg420atgacgatta ctctttttgc agagctctga agggagagac tgtgaataca acaatatcat480tctccttcaa gggaataaaa ttttctaagg gaaaatacaa atgtgttgtt gaagctattt540ctgggagccc agaagaaatg ctcttttgct tggagtttgt catcctacac caacctaatt600caaattagaa taaattgagt attt 624<210>60<211>2088<212>DNA<213>人<400>60gaattcggca cgagcgcgcg gcgaatctca acgctgcgcc gtctgcgggc gcttccgggc60
caccagtttc tctgctttcc accctggcgc cccccagccc tggctcccca gctgcgctgc 120cccgggcgtc cacgccctgc gggcttagcg ggttcagtgg gctcaatctg cgcagcgcca 180cctccatgtt gaccaagcct ctacaggggc ctcccgcgcc ccccgggacc cccacgccgc 240cgccaggagg caaggatcgg gaagcgttcg aggccgagta tcgactcggc cccctcctgg 300gtaagggggg ctttggcacc gtcttcgcag gacaccgcct cacagatcga ctccaggtgg 360ccatcaaagt gattccccgg aatcgtgtgc tgggctggtc ccccttgtca gactcagtca 420catgcccact cgaagtcgca ctgctatgga aagtgggtgc aggtggtggg caccctggcg 480tgatccgcct gcttgactgg tttgagacac aggaaggctt catgctggtc ctcgagcggc 540ctttgcccgc ccaggatctc tttgactata tcacagagaa gggcccactg ggtgaaggcc 600caagccgctg cttctttggc caagtagtgg cagccatcca gcactgccat tcccgtggag 660ttgtccatcg tgacatcaag gatgagaaca tcctgataga cctacgccgt ggctgtgcca 720aactcattga ttttggttct ggtgccctgc ttcatgatga accctacact gactttgatg 780ggacaagggt gtacagcccc ccagagtgga tctctcgaca ccagtaccat gcactcccgg 840ccactgtctg gtcactgggc atcctcctct atgacatggt gtgtggggac attccctttg 900agagggacca ggagattctg gaagctgagc tccacttccc agcccatgtc tccccagact 960gctgtgccct aatccgccgg tgcctggccc ccaaaccttc ttcccgaccc tcactggaag1020agatcctgct ggacccctgg atgcaaacac cagccgagga tgttacccct caacccctcc1080aaaggaggcc ctgccccttt ggcctggtcc ttgctaccct aagcctggcc tggcctggcc1140tggcccccaa tggtcagaag agccatccca tggccatgtc acagggatag atggacattt1200gttgacttgg ttttacaggt cattaccagt cattaaagtc cagtattact aaggtaaggg1260attgaggatc aggggttaga agacataaac caagtttgcc cagttccctt cccaatccta1320caaaggagcc ttcctcccag aacctgtggt ccctgatttt ggagggggaa cttcttgctt1380ctcattttgc taaggaagtt tattttggtg aagttgttcc cattttgagc cccgggactc1440ttattttgat gatgtgtcac cccacattgg cacctcctac taccaccaca caaacttagt1500tcatatgctt ttacttgggc aagggtgctt tccttccaat accccagtag cttttatttt1560agtaaaggga ccctttcccc tagcctaggg tcccatattg ggtcaagctg cttacctgcc1620tcagcccagg attttttatt ttgggggagg taatgccctg ttgttacccc aaggcttctt1680tttttttttt tttttttttg ggtgagggga ccctactttg ttatcccaag tgctcttatt1740ctggtgagaa gaaccttaat tccataattt gggaaggaat ggaagatgga caccaccgga1800caccaccaga caataggatg ggatggatgg ttttttgggg gatgggctag gggaaataag1860gcttgctgtt tgttttcctg gggcgctccc tccaattttg cagatttttg caacctcctc1920ctgagccggg attgtccaat tactaaaatg taaataatca cgtattgtgg ggaggggagt1980tccaagtgtg ccctcctttt ttttcctgcc tggattattt aaaaagccat gtgtggaaac2040ccactattta ataaaagtaa tagaatcaga aaaaaaaaaa aaaaaaaa 2088
<210>61<211>2270<212>DNA<213>人<400>61ctcctccagc ctctcacact ctcctcagct ctctcatctc ctggaaccat ggccagcaca 60tccaccacca tcaggagcca cagcagcagc cgccggggtt tcagtgccaa ctcagccagg 120ctccctgggg tcagccgctc tggcttcagc agcgtctccg tgtcccgctc caggggcagt 180ggtggcctgg gtggtgcatg tggaggagct ggctttggca gccgcagtct gtatggcctg 240gggggctcca agaggatctc cattggaggg ggcagctgtg ccatcagtgg cggctatggc 300agcagagccg gaggcagcta tggctttggt ggcgccggga gtggatttgg tttcggtggt 360ggagccggca ttggctttgg tctgggtggt ggagccggcc ttgctggtgg ctttgggggc 420cctggcttcc ctgtgtgccc ccctggaggc atccaagagg tcaccgtcaa ccagagtctc 480ctgactcccc tcaacctgca aatcgatccc accatccagc gggtgcgggc tgaggagcgt 540gaacagatca agaccctcaa caacaagttt gcctccttca tcgacaaggt gcggttcctg 600gagcagcaga acaaggttct ggaaacaaag tggaccctgc tgcaggagca gggcaccaag 660actgtgaggc agaacctgga gccgttgttc gagcagtaca tcaacaacct caggaggcag 720ctggacagca ttgtcgggga acggggccgc ctggactcag agctcagagg catgcaggac 780ctggtggagg acttcaagaa caaatatgag gatgaaatca acaagcgcac agcagcagag 840aatgaatttg tgactctgaa gaaggatgtg gatgctgcct acatgaacaa ggttgaactg 900caagccaagg cagacactct cacagacgag atcaacttcc tgagagcctt gtatgatgca 960gagctgtccc agatgcagac ccacatctca gacacatctg tggtgctgtc catggacaac1020aaccgcaacc tggacctgga cagcatcatc gctgaggtca aggcccaata tgaggagatt1080gctcagagaa gccgggctga ggctgagtcc tggtaccaga ccaagtacga ggagctgcag1140gtcacagcag gcagacatgg ggacgacctg cgcaacacca agcaggagat tgctgagatc1200aaccgcatga tccagaggct gagatctgag atcgaccacg tcaagaagca gtgcgccaac1260ctgcaggccg ccattgctga tgctgagcag cgtggggaga tggccctcaa ggatgccaag1320aacaagctgg aagggctgga ggatgccctg cagaaggcca agcaggacct ggcccggctg1380ctgaaggagt accaggagct gatgaatgtc aagctggccc tggacgtgga gatcgccacc1440taccgcaagc tgctggaggg tgaggagtgc aggctgaatg gcgaaggcgt tggacaagtc1500aacatctctg tggtgcagtc caccgtctcc agtggctatg gcggtgccag tggtgtcggc1560agtggcttag gcctgggtgg aggaagcagc tactcctatg gcagtggtct tggcgttgga1620ggtggcttca gttccagcag tggcagagcc attgggggtg gcctcagctc tgttggaggc1680ggcagttcca ccatcaagta caccaccacc tcctcctcca gcaggaagag ctataagcac1740taaagtgcgt ctgctagctc tcggtcccac agtcctcagg cccctctctg gctgcagagc1800cctctcctca ggttgcctgt cctctcctgg cctccagtct cccctgctgt cccaggtaga1860
gctggggatg aatgcttagt gccctcactt cttctctctc tctctatacc atctgagcac1920ccattgctca ccatcagatc aacctctgat tttacatcat gatgtaatca ccactggagc1980ttcactgtta ctaaattatt aatttcttgc ctccagtgtt ctatctctga ggctgagcat2040tataagaaaa tgacctctgc tccttttcat tgcagaaaat tgccaggggc ttatttcaga2100acaacttcca cttactttcc actggctctc aaactctcta acttataagt gttgtgaacc2160cccacccagg cagtatccat gaaagcacaa gtgactagtc ctatgatgta caaagcctgt2220atctctgtga tgatttctgt gctcttcact gtttgcaatt gctaaataaa 2270<210>62<211>2048<212>DNA<213>人<400>62atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt1020gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga1080tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac1140tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag1200cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt1260gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat1320acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt1380tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt1440
ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc1500tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa1560cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca1620ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt1680taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta1740agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac1800ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata1860tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc1920atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc1980cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa2040ctaaaccg 2048<210>63<211>2048<212>DNA<213>人<400>63atgtgaaggc acaagctgct gttatataca acagagtgaa ctgagcatca gtcagaaaaa 60gtctatgttt gcagaaatac agatccaaga caaagacagg atgggcactg ctggaaaagt 120tattaaatgc aaagcagctg tgctttggga gcagaagcaa cccttctcca ttgaggaaat 180agaagttgcc ccaccaaaga ctaaagaagt tcgcattaag attttggcca caggaatctg 240tcgcacagat gaccatgtga taaaaggaac aatggtgtcc aagtttccag tgattgtggg 300acatgaggca actgggattg tagagagcat tggagaagga gtgactacag tgaaaccagg 360tgacaaagtc atccctctct ttctgccaca atgtagagaa tgcaatgctt gtcgcaaccc 420agatggcaac ctttgcatta ggagcgatat tactggtcgt ggagtactgg ctgatggcac 480caccagattt acatgcaagg gcaaaccagt acaccacttc atgaacacca gtacatttac 540cgagtacaca gtggtggatg aatcttctgt tgctaagatt gatgatgcag ctcctcctga 600gaaagtctgt ttaattggct gtgggttttc cactggatat ggcgctgctg ttaaaactgg 660caaggtcaaa cctggttcca cttgcgtcgt ctttggcctg ggaggagttg gcctgtcagt 720catcatgggc tgtaagtcag ctggtgcatc taggatcatt gggattgacc tcaacaaaga 780caaatttgag aaggccatgg ctgtaggtgc cactgagtgt atcagtccca aggactctac 840caaacccatc agtgaggtgc tgtcagaaat gacaggcaac aacgtgggat acacctttga 900agttattggg catcttgaaa ccatgattga tgccctggca tcctgccaca tgaactatgg 960gaccagcgtg gttgtaggag ttcctccatc agccaagatg ctcacctatg acccgatgtt1020gctcttcact ggacgcacat ggaagggatg tgtctttgga ggtttgaaaa gcagagatga1080tgtcccaaaa ctagtgactg agttcctggc aaagaaattt gacctggacc agttgataac1140tcatgtttta ccatttaaaa aaatcagtga aggatttgag ctgctcaatt caggacaaag1200
cattcgaacg gtcctgacgt tttgagatcc aaagtggcag gaggtctgtg ttgtcatggt1260gaactggagt ttctcttgtg agagttccct catctgaaat catgtatctg tctcacaaat1320acaagcataa gtagaagatt tgttgaagac atagaaccct tataaagaat tattaacctt1380tataaacatt taaagtcttg tgagcacctg ggaattagta taataacaat gttaatattt1440ttgatttaca ttttgtaagg ctataattgt atcttttaag aaaacataca cttggatttc1500tatgttgaaa tggagatttt taagagtttt aaccagctgc tgcagatata taactcaaaa1560cagatatagc gtataaagat atagtaaatg catctcccag agtaatattc acttaacaca1620ttgaaactat tattttttag atttgaatat aaatgtattt tttaaacact tgttatgagt1680taacttggat tacattttga aatcagttca ttccatgatg catattactg gattagatta1740agaaagacag aaaagattaa gggacgggca catttttcaa cgattaagaa tcatcattac1800ataacttggt gaaactgaaa aagtatatca tatgggtaca caaggctatt tgccagcata1860tattaatatt ttagaaaata ttccttttgt aatactgaat ataaacatag agctagagtc1920atattatcat acttatcata atgttcaatt tgatacagta gaattgcaag tccctaagtc1980cctattcact gtgcttagta gtgactccat ttaataaaaa gtgtttttag tttttaacaa2040ctaaaccg 2048<210>64<211>2816<212>DNA<213>人<400>64tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960
tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat1020gggcaagtcctgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac 1080aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt1140gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag1200aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat1260gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca1320attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc1380ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct1440gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc1500tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta1560tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga1620cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct1680ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag1740gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg1800gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa1860aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag1920aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga1980cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg2040tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc2100tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat2160gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta2220catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa2280ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt2340tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt2400aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta2460ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc2520agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt2580ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt2640ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt2700caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt2760ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa2816<210>65<211>2816<212>DNA<213>人<400>65
tcgttgatat caaagacagt tgaaggaaat gaattttgaa acttcacggt gtgccaccct 60acagtactgc cctgaccctt acatccagcg tttcgtagaa acccagctca tttctcttgg 120aaagaaagtt attaccgatc caccatgtcc cagagcacac agacaaatga attcctcagt 180ccagaggttt tccagcatat ctgggatttt ctggaacagc ctatatgttc agttcagccc 240attgacttga actttgtgga tgaaccatca gaagatggtg cgacaaacaa gattgagatt 300agcatggact gtatccgcat gcaggactcg gacctgagtg accccatgtg gccacagtac 360acgaacctgg ggctcctgaa cagcatggac cagcagattc agaacggctc ctcgtccacc 420agtccctata acacagacca cgcgcagaac agcgtcacgg cgccctcgcc ctacgcacag 480cccagctcca ccttcgatgc tctctctcca tcacccgcca tcccctccaa caccgactac 540ccaggcccgc acagtttcga cgtgtccttc cagcagtcga gcaccgccaa gtcggccacc 600tggacgtatt ccactgaact gaagaaactc tactgccaaa ttgcaaagac atgccccatc 660cagatcaagg tgatgacccc acctcctcag ggagctgtta tccgcgccat gcctgtctac 720aaaaaagctg agcacgtcac ggaggtggtg aagcggtgcc ccaaccatga gctgagccgt 780gaattcaacg agggacagat tgcccctcct agtcatttga ttcgagtaga ggggaacagc 840catgcccagt atgtagaaga tcccatcaca ggaagacaga gtgtgctggt accttatgag 900ccaccccagg ttggcactga attcacgaca gtcttgtaca atttcatgtg taacagcagt 960tgtgttggag ggatgaaccg ccgtccaatt ttaatcattg ttactctgga aaccagagat1020gggcaagtcc tgggccgacg ctgctttgag gcccggatct gtgcttgccc aggaagagac1080aggaaggcgg atgaagatag catcagaaag cagcaagttt cggacagtac aaagaacggt1140gatggtacga agcgcccgtt tcgtcagaac acacatggta tccagatgac atccatcaag1200aaacgaagat ccccagatga tgaactgtta tacttaccag tgaggggccg tgagacttat1260gaaatgctgt tgaagatcaa agagtccctg gaactcatgc agtaccttcc tcagcacaca1320attgaaacgt acaggcaaca gcaacagcag cagcaccagc acttacttca gaaacatctc1380ctttcagcct gcttcaggaa tgagcttgtg gagccccgga gagaaactcc aaaacaatct1440gacgtcttct ttagacattc caagccccca aaccgatcag tgtacccata gagccctatc1500tctatatttt aagtgtgtgt gttgtatttc catgtgtata tgtgagtgtg tgtgtgtgta1560tgtgtgtgcg tgtgtatcta gccctcataa acaggacttg aagacacttt ggctcagaga1620cccaactgct caaaggcaca aagccactag tgagagaatc ttttgaaggg actcaaacct1680ttacaagaaa ggatgttttc tgcagatttt gtatccttag accggccatt ggtgggtgag1740gaaccactgt gtttgtctgt gagctttctg ttgtttcctg ggagggaggg gtcaggtggg1800gaaaggggca ttaagatgtt tattggaacc cttttctgtc ttcttctgtt gtttttctaa1860aattcacagg gaagcttttg agcaggtctc aaacttaaga tgtcttttta agaaaaggag1920aaaaaagttg ttattgtctg tgcataagta agttgtaggt gactgagaga ctcagtcaga1980cccttttaat gctggtcatg taataatatt gcaagtagta agaaacgaag gtgtcaagtg2040tactgctggg cagcgaggtg atcattacca aaagtaatca actttgtggg tggagagttc2100
tttgtgagaa cttgcattat ttgtgtcctc ccctcatgtg taggtagaac atttcttaat2160gctgtgtacc tgcctctgcc actgtatgtt ggcatctgtt atgctaaagt ttttcttgta2220catgaaaccc tggaagacct actacaaaaa aactgttgtt tggcccccat agcaggtgaa2280ctcattttgt gcttttaata gaaagacaaa tccaccccag taatattgcc cttacgtagt2340tgtttaccat tattcaaagc tcaaaataga atttgaagcc ctctcacaaa atctgtgatt2400aatttgctta attagagctt ctatccctca agcctaccta ccataaaacc agccatatta2460ctgatactgt tcagtgcatt tagccaggag acttacgttt tgagtaagtg agatccaagc2520agacgtgtta aaatcagcac tcctggactg gaaattaaag attgaaaggg tagactactt2580ttcttttttt tactcaaaag tttagagaat ctctgtttct ttccatttta aaaacatatt2640ttaagataat agcataaaga ctttaaaaat gttcctcccc tccatcttcc cacacccagt2700caccagcact gtattttctg tcaccaagac aatgatttct tgttattgag gctgttgctt2760ttgtggatgt gtgattttaa ttttcaataa acttttgcat cttggtttaa aagaaa2816<210>66<211>5838<212>DNA<213>人<400>66ccgggcaggt ggctcatgct cgggagcgtg gttgagcggc tggcgcggtt gtcctggagc 60aggggcgcag gaattctgat gtgaaactaa cagtctgtga gccctggaac ctccgctcag 120agaagatgaa ggatatcgac ataggaaaag agtatatcat ccccagtcct gggtatagaa 180gtgtgaggga gagaaccagc acttctggga cgcacagaga ccgtgaagat tccaagttca 240ggagaactcg accgttggaa tgccaagatg ccttggaaac agcagcccga gccgagggcc 300tctctcttga tgcctccatg cattctcagc tcagaatcct ggatgaggag catcccaagg 360gaaagtacca tcatggcttg agtgctctga agcccatccg gactacttcc aaacaccagc 420acccagtgga caatgctggg cttttttcct gtatgacttt ttcgtggctt tcttctctgg 480cccgtgtggc ccacaagaag ggggagctct caatggaaga cgtgtggtct ctgtccaagc 540acgagtcttc tgacgtgaac tgcagaagac tagagagact gtggcaagaa gagctgaatg 600aagttgggcc agacgctgct tccctgcgaa gggttgtgtg gatcttctgc cgcaccaggc 660tcatcctgtc catcgtgtgc ctgatgatca cgcagctggc tggcttcagt ggaccagcct 720tcatggtgaa acacctcttg gagtataccc aggcaacaga gtctaacctg cagtacagct 780tgttgttagt gctgggcctc ctcctgacgg aaatcgtgcg gtcttggtcg cttgcactga 840cttgggcatt gaattaccga accggtgtcc gcttgcgggg ggccatccta accatggcat 900ttaagaagat ccttaagtta aagaacatta aagagaaatc cctgggtgag ctcatcaaca 960tttgctccaa cgatgggcag agaatgtttg aggcagcagc cgttggcagc ctgctggctg1020gaggacccgt tgttgccatc ttaggcatga tttataatgt aattattctg ggaccaacag1080gcttcctggg atcagctgtt tttatcctct tttacccagc aatgatgttt gcatcacggc1140
tcacagcata tttcaggaga aaatgcgtgg ccgccacgga tgaacgtgtc cagaagatga1200atgaagttct tacttacatt aaatttatca aaatgtatgc ctgggtcaaa gcattttctc1260agagtgttca aaaaatccgc gaggaggagc gtcggatatt ggaaaaagcc gggtacttcc1320agggtatcac tgtgggtgtg gctcccattg tggtggtgat tgccagcgtg gtgaccttct1380ctgttcatat gaccctgggc ttcgatctga cagcagcaca ggctttcaca gtggtgacag1440tcttcaattc catgactttt gctttgaaag taacaccgtt ttcagtaaag tccctctcag1500aagcctcagt ggctgttgac agatttaaga gtttgtttct aatggaagag gttcacatga1560taaagaacaa accagccagt cctcacatca agatagagat gaaaaatgcc accttggcat1620gggactcctc ccactccagt atccagaact cgcccaagct gacccccaaa atgaaaaaag1680acaagagggc ttccaggggc aagaaagaga aggtgaggca gctgcagcgc actgagcatc1740aggcggtgct ggcagagcag aaaggccacc tcctcctgga cagtgacgag cggcccagtc1800ccgaagagga agaaggcaag cacatccacc tgggccacct gcgcttacag aggacactgc1860acagcatcga tctggagatc caagagggta aactggttgg aatctgcggc agtgtgggaa1920gtggaaaaac ctctctcatt tcagccattt taggccagat gacgcttcta gagggcagca1980ttgcaatcag tggaaccttc gcttatgtgg cccagcaggc ctggatcctc aatgctactc2040tgagagacaa catcctgttt gggaaggaat atgatgaaga aagatacaac tctgtgctga2100acagctgctg cctgaggcct gacctggcca ttcttcccag cagcgacctg acggagattg2160gagagcgagg agccaacctg agcggtgggc agcgccagag gatcagcctt gcccgggcct2220tgtatagtga caggagcatc tacatcctgg acgaccccct cagtgcctta gatgcccatg2280tgggcaacca catcttcaat agtgctatcc ggaaacatct caagtccaag acagttctgt2340ttgttaccca ccagttacag tacctggttg actgtgatga agtgatcttc atgaaagagg2400gctgtattac ggaaagaggc acccatgagg aactgatgaa tttaaatggt gactatgcta2460ccatttttaa taacctgttg ctgggagaga caccgccagt tgagatcaat tcaaaaaagg2520aaaccagtgg ttcacagaag aagtcacaag acaagggtcc taaaacagga tcagtaaaga2580aggaaaaagc agtaaagcca gaggaagggc agcttgtgca gctggaagag aaagggcagg2640gttcagtgcc ctggtcagta tatggtgtct acatccaggc tgctgggggc cccttggcat2700tcctggttat tatggccctt ttcatgctga atgtaggcag caccgccttc agcacctggt2760ggttgagtta ctggatcaag caaggaagcg ggaacaccac tgtgactcga gggaacgaga2820cctcggtgag tgacagcatg aaggacaatc ctcatatgca gtactatgcc agcatctacg2880ccctctccat ggcagtcatg ctgatcctga aagccattcg aggagttgtc tttgtcaagg2940gcacgctgcg agcttcctcc cggctgcatg acgagctttt ccgaaggatc cttcgaagcc3000ctatgaagtt ttttgacacg acccccacag ggaggattct caacaggttt tccaaagaca3060tggatgaagt tgacgtgcgg ctgccgttcc aggccgagat gttcatccag aacgttatcc3120tggtgttctt ctgtgtggga atgatcgcag gagtcttccc gtggttcctt gtggcagtgg3180
ggccccttgt catcctcttt tcagtcctgc acattgtctc cagggtcctg attcgggagc 3240tgaagcgtct ggacaatatc acgcagtcac ctttcctctc ccacatcacg tccagcatac 3300agggccttgc caccatccac gcctacaata aagggcagga gtttctgcac agataccagg 3360agctgctgga tgacaaccaa gctccttttt ttttgtttac gtgtgcgatg cggtggctgg 3420ctgtgcggct ggacctcatc agcatcgccc tcatcaccac cacggggctg atgatcgttc 3480ttatgcacgg gcagattccc ccagcctatg cgggtctcgc catctcttat gctgtccagt 3540taacggggct gttccagttt acggtcagac tggcatctga gacagaagct cgattcacct 3600cggtggagag gatcaatcac tacattaaga ctctgtcctt ggaagcacct gccagaatta 3660agaacaaggc tccctcccct gactggcccc aggagggaga ggtgaccttt gagaacgcag 3720agatgaggta ccgagaaaac ctccctcttg tcctaaagaa agtatccttc acgatcaaac 3780ctaaagagaa gattggcatt gtggggcgga caggatcagg gaagtcctcg ctggggatgg 3840ccctcttccg tctggtggag ttatctggag gctgcatcaa gattgatgga gtgagaatca 3900gtgatattgg ccttgccgac ctccgaagca aactctctat cattcctcaa gagccggtgc 3960tgttcagtgg cactgtcaga tcaaatttgg accccttcaa ccagtacact gaagaccaga 4020tttgggatgc cctggagagg acacacatga aagaatgtat tgctcagcta cctctgaaac 4080ttgaatctga agtgatggag aatggggata acttctcagt gggggaacgg cagctcttgt 4140gcatagctag agccctgctc cgccactgta agattctgat tttagatgaa gccacagctg 4200ccatggacac agagacagac ttattgattc aagagaccat ccgagaagca tttgcagact 4260gtaccatgct gaccattgcc catcgcctgc acacggttct aggctccgat aggattatgg 4320tgctggccca gggacaggtg gtggagtttg acaccccatc ggtccttctg tccaacgaca 4380gttcccgatt ctatgccatg tttgctgctg cagagaacaa ggtcgctgtc aagggctgac 4440tcctccctgt tgacgaagtc tcttttcttt agagcattgc cattccctgc ctggggcggg 4500cccctcatcg cgtcctccta ccgaaacctt gcctttctcg attttatctt tcgcacagca 4560gttccggatt ggcttgtgtg tttcactttt agggagagtc atattttgat tattgtattt 4620attccatatt catgtaaaca aaatttagtt tttgttctta attgcactct aaaaggttca 4680gggaaccgtt attataattg tatcagaggc ctataatgaa gctttatacg tgtagctata 4740tctatatata attctgtaca tagcctatat ttacagtgaa aatgtaagct gtttatttta 4800tattaaaata agcactgtgc taataacagt gcatattcct ttctatcatt tttgtacagt 4860ttgctgtact agagatctgg ttttgctatt agactgtagg aagagtagca tttcattctt 4920ctctagctgg tggtttcacg gtgccaggtt ttctgggtgt ccaaaggaag acgtgtggca 4980atagtgggcc ctccgacagc cccctctgcc gcctccccac agccgctcca ggggtggctg 5040gagacgggtg ggcggctgga gaccatgcag agcgccgtga gttctcaggg ctcctgcctt 5100ctgtcctggt gtcacttact gtttctgtca ggagagcagc ggggcgaagc ccaggcccct 5160tttcactccc tccatcaaga atggggatca cagagacatt cctccgagcc ggggagtttc 5220tttcctgcct tcttcttttt gctgttgttt ctaaacaaga atcagtctat ccacagagag 5280
tcccactgcc tcaggttcct atggctggcc actgcacaga gctctccagc tccaagacct 5340gttggttcca agccctggag ccaactgctg ctttttgagg tggcactttt tcatttgcct 5400attcccacac ctccacagtt cagtggcagg gctcaggatt tcgtgggtct gttttccttt 5460ctcaccgcag tcgtcgcaca gtctctctct ctctctcccc tcaaagtctg caactttaag 5520cagctcttgc taatcagtgt ctcacactgg cgtagaagtt tttgtactgt aaagagacct 5580acctcaggtt gctggttgct gtgtggtttg gtgtgttccc gcaaaccccc tttgtgctgt 5640ggggctggta gctcaggtgg gcgtggtcac tgctgtcatc agttgaatgg tcagcgttgc 5700atgtcgtgac caactagaca ttctgtcgcc ttagcatgtt tgctgaacac cttgtggaag 5760caaaaatctg aaaatgtgaa taaaattatt ttggattttg taaaaaaaaa aaaaaaaaaa 5820aaaaaaaaaa aaaaaaaa 5838<210>67<211>6841<212>DMA<213>人<400>67gccggagggc gcccgagggg ccccgggccg cggcgctcag ggcccgggcg gccggcggcg 60gccccggggc tggggggagt ccagcccgga tattgagtgc agccattgag aaaagccaaa 120ctcttgtgtg tgcgcgtctc gatagccccc aagatggccg ccaatgtggg atcgatgttt 180caatattgga agcgatttga tctacggcga ctccagaagg agcttaattc cgtcgcttct 240gagctgtctg cacggcagga ggagagtgaa cattctcata aacatttaat tgaactccgc 300cgggaattta agaaaaatgt acctgaggaa atcagagaga tggtggctcc tgtattaaaa 360agcttccaag ccgaggtggt ggcccttagt aagagaagtc aggaggcgga ggctgctttt 420ctgagtgttt acaagcaatt aattgaagca ccagaccccg tgcctgtgtt tgaggcggca 480cgcagcctag acgacagact gcagcccccc agctttgacc ccagtgggca gccccggcga 540gacctccaca cttcgtggaa gaggaacccc gagctcctca gccccaaaga gcagagagag 600gggacgtcgc ctgccgggcc cacgctgacc gagggaagcc gcctcccagg cattcccggg 660aaagccctcc tgacagaaac cttgctgcag agaaatgagg cggaaaaaca aaagggcctt 720caagaagtac agatcacttt ggcggccaga ctgggggagg cagaggagaa aatcaaagtc 780ctacattcag cgctaaaggc tacgcaggca gagctgctag agctgcggcg gaagtacgac 840gaggaggcag catccaaggc agatgaagtc ggcctgatca tgaccaacct ggagaaagct 900aatcagcgag ctgaggctgc ccagcgggag gtggaaagtc tccgggaaca gctggcctct 960gtcaacagct ccatccgcct ggcttgctgc tctccccagg ggcccagtgg ggataaggtg1020aacttcactc tgtgctcggg ccctcggctg gaggccgcgc tggcctccaa ggacagggag1080atcctgcggc tgctgaagga cgtgcagcac ctccagagct cactgcagga gctggaggag1140gcatccgcca accagatcgc cgacctggag cggcagctca cggccaagtc cgaggccata1200gaaaagctgg aagagaagct ccaggcccag tctgactatg aggaaattaa aacggagctg1260
agcatcctga aagccatgaa gctggcctcc agcacctgca gcctccccca gggcatggcc1320aagcctgaag actcactgct tattgcaaag gaggccttct tccccacgca gaaattcctt1380ctggagaagc ccagcctcct ggccagccct gaggaagacc catcagagga cgattccatc1440aaggattcac tgggcacgga gcagtcctac ccctcccctc agcagctccc acctccacca1500gggccagaag accccctgtc tcccagcccc gggcagcccc tgctgggccc cagcttgggg1560cctgacggca ctcggacttt ctcgctgtcc cccttcccca gcctggcatc aggggagaga1620ctgatgatgc ccccagccgc cttcaaggga gaggcgggcg gcctgctggt gttcccccca1680gccttctatg gcgccaagcc ccccacagcc cctgccaccc cggcccctgg ccctgagcca1740ctgggcggtc ctgagcccgc ggatggtggt gggggcggag cggcggggcc cggggcagag1800gaggagcagc tggacacggc agagatcgcc ttccaggtga aggagcagct gctgaaacac1860aacatcgggc agcgggtgtt tgggcattac gtgctggggc tgtcgcaggg ctcggtcagc1920gagatcctag cccggcccaa gccctggcgc aagctcacgg tgaagggcaa ggagcccttc1980atcaagatga agcagttcct gtcggatgag cagaatgtac tggcgctcag gaccatccaa2040gtgcggcagc gaggcagcat caccccgaga atccgcacgc ctgagacagg ctcagacgac2100gccatcaaga gcattctaga gcaggccaag aaggagatcg agtcgcagaa gggcggcgag2160cccaagacct cggtggcccc gctgagcatc gccaacggca cgacccccgc cagcacctcg2220gaggacgcca tcaagagcat cctggagcag gcacgccgtg agatgcaggc gcaacagcag2280gcgctgctgg agatggaggt ggcgcccagg ggccgctcgg tgcccccctc gcccccggag2340cggccatcac tggccaccgc gagccagaac ggggccccgg ccttggtgaa gcaggaggag2400ggcagcgggg gccccgcgca ggcgccgctc ccggtcctgt cccccgccgc cttcgtgcag2460agcatcatcc gcaaggtcaa gtccgagatc ggcgacgccg gctacttcga ccaccactgg2520gcctccgacc gcggcctgct cagccgcccc tacgcctccg tgtcgccctc gctgtcctcc2580tcctcctcct ctggctactc tggccagccc aacggccgcg cctggccccg cggggacgag2640gcccctgtgc cccccgagga cgaggcggcg gcaggggcgg aggacgaacc ccccaggacg2700ggcgagctca aggctgaggg cgcgacggcc gaggcgggcg cgcggctgcc ctactacccg2760gcctacgtgc cgcgcaccct gaagcccacc gtgccgccgc tgacccccga gcagtacgag2820ctgtacatgt accgtgaggt agacacgctg gagctcaccc gccaggtcaa ggagaagctg2880gccaagaacg gcatctgcca gaggatcttc ggggagaagg tgctgggcct gtcacagggc2940agcgtgagcg acatgctgtc ccggccgaag ccatggagca agctgacgca gaaggggcgg3000gagcccttca tccgcatgca gctgtggctc tctgaccagc tcggccaggc agtgggccag3060cagcctggtg cctcccaggc cagtcccaca gaaccaaggt cctcaccatc cccacccccc3120agccccacag agcctgagaa gagctcccag gagccgttga gcctgtccct ggagagcagc3180aaggagaacc agcagccaga gggccgctcc agctcctcgt tgagcgggaa gatgtactca3240ggcagccagg ccccaggggg catccaggag atcgtggcca tgtcccccga gctggacacg3300
tactccatca ccaagagggt gaaggaggtc ctcacagaca acaatctagg gcagcggctg 3360tttggggaaa gcatcctggg tctgacacag ggctccgtgt ctgacctgct gtcccggccc 3420aaaccctggc acaagctgag cctgaagggg cgggagcctt ttgtccgcat gcagctgtgg 3480ctcaatgacc cccataacgt ggagaagctg agggatatga agaagctgga gaagaaagcc 3540tacctgaaac gtcgctatgg cctcatcagc accggctcag acagtgagtc cccggccacc 3600cgctcagagt gccccagccc ctgcctgcag ccccaggacc tgagcctcct gcagatcaag 3660aagccccggg tggtgctggc acccgaggag aaggaggcac tgcggaaggc ctatcagctg 3720gaaccctacc cctcgcagca gaccatcgag ctcctctcct tccagctcaa cctcaagacc 3780aacaccgtca tcaactggtt ccacaactac aggtcccgga tgcgccggga gatgttggtg 3840gaggggaccc aggatgagcc agaccttgat ccaagcgggg gtcctggaat cctaccgcca 3900ggccactccc acccagaccc caccccgcag agccctgact ctgagactga ggaccagaag 3960ccaaccgtga aggaactgga gcttcaggag ggccctgagg agaacagcac acccctgacc 4020acccaggaca aggcccaagt gaggatcaag caggaacaga tggaggagga tgctgaggaa 4080gaggcaggca gccagcccca ggactcaggg gagctggaca aaggccaagg tccccccaaa 4140gaggagcatc ccgaccctcc gggtaatgat ggactcccaa aagtggctcc cgggcccctc 4200cttccaggtg gatccacccc agactgtccc tcacttcatc cccaacagga gagtgaggcc 4260ggggagcgac ttcacccgga ccctttaagt tttaagtcag cctcagagtc ctcacgctgc 4320agcctggagg tgtcactgaa ctcgccctcg gccgcctcct caccaggcct catgatgtct 4380gtgtcacctg tcccctcctc ctcagctccc atctccccat ccccacctgg cgccccccct 4440gccaaagtgc cgagtgccag ccccactgct gacatggctg gagccttgca ccccagtgcc 4500aaggtgaacc ccaacttgca gcggcggcat gagaagatgg ccaatctgaa caacatcatt 4560taccgactag agcgggctgc caatcgggag gaggccctgg agtgggagtt ctgaaggcag 4620ggtgaggggg caagggacat accctggtaa ctaccttcct tctcgcactt actctcctca 4680acaggatggg gtaagggagg gaggaactca accatcaaaa tgtggacagc aatgttatgc 4740cgtttacgtt ttttgttgta atcctagttc tatgaagctg tgtgagcagg tgggtcaaat 4800gccattgcct ccacttttct gcacccccct gctcctcttc accctgaccc ctctgcagga 4860ggcagaagca aaatggcacc acatattcac ctgaaaactc caaactcttt tagaaaaata 4920aataaatatt tatagacctc ttttagatat tttaataaag gatcctttgg aatttatccc 4980agctgatgct gttttgatat tacagagagt tataaaatca ggatgctgtc acaactgttg 5040cgaagtatac actgaagttg tgtcgttttt gccactagat gagattaaaa gaagacaatt 5100attcaaagcc atcacaaaac actataagac tgaccaaaat ttagataacc tttgaaccac 5160gatttttttc cacatctgtc tgtgagacac agcgcaatgc tactgccctt ccagaaactg 5220tgctaaaaag agaaagtcca aaagactcta aacaaaaacc tcgacgccgt tgaggatgtg 5280tttcattctg gtggtctgtt ttgcaagctt gataacagaa tgtccgtgcc attgtaaatg 5340ttgtagagat gtgggccgtg gcccaaccgt cctatatgag atgtagcatg gtacagaaca 5400
aactgcttac acaggtctca ctagttagaa acctgtgggc catggaggtc agacatccat5460cttgtccatc tataggcaag aagtgtttcc agatcctttg gaaaggtggg catggggcag5520gtgcttggag agtggcgttt gagccagagc gaccccattt cccgtgtgaa ccataggcac5580aacccaggaa gtttccccac ttgtaggagt gtgggtattc cagagcaaga ctgtggccac5640catcttcccc tcttggtgtt ttccgaaagt gacagtgttg gtcatcccat gaccactgaa5700gcttagtaac cagcgccaaa aagtagattc atcaaactag agaccccagc tccccttctc5760gccatcttct ttctcaagtt gaccgtggtg ctgtttctgg aaggcatctg caactccaag5820tccatgcaga actctggaag gccaagttca tcgcagcatg ttcaccatat cccagcctcc5880aaatctatcc tcctaccttc caacgcatga cctgttgggg agcagagact taacccccaa5940ctcagaggaa cccttcctcc agcgtctttg gcatggtttc tagggtgaga gttcccaatt6000tggatagaac ggccaccata ttggttactg aatctctctc ccttgttttt attacgtttc6060ctttttcaaa ctgtccatgg gaaggctgaa ttgagtgact ccccagaatg aagatgagaa6120ggtgaatata atcaatgcca atgtaatgcc agcgggtgag atggccgatg gaggtttcaa6180agatgtagct agcattttga aaccatatgg gcaaaacccg gcaaccagaa ggggacagat6240aaggaccgtt ccagaaatcc caactctcac acccagccca ggctgcagtc tccacaccaa6300acagtcaaca aaacacaaac cctgaaggaa aaccttttcc atacacccag gctatgcatt6360gaagagtttt ccactgtata catttttatc cagatgaagg tatttttata ttttgacaat6420aggaaacagt gaccattttc agagtaatca aatctggaac aaatgaaaca tcttttagcc6480accaccaccc tgttgcaatt aagacaaccg tgggggaaca caccactttt tactgttgaa6540accaacacaa cgttgaaatc caggcttata cgcagactcc gattcctaga gaactaaatt6600tggctttagt gtgacgggat ttgattaagc acttagtata gtcttttgaa cacggaaatc6660ctgttgtact taaagctagc ggacccgtga acaactttgt caggttcacg tcctataacg6720gttaaaaaac acacacacac atacacaaac cgtttctatg agagattgat gaactttgtt6780taaaatttta aaaaaaggaa cacgttctgt aaacgagtcg ctaaatacag aattgtataa6840t6841<210>68<211>1181<212>DNA<213>人<400>68ggcacgaggc ccgggccccc caaagtcccg gccgggccga gggtcggcgg ccgccggcgg 60gccgggcccg cgcacagcgc ccgcatgtac aacatgatgg agacggagct gaagccgccg 120ggcccgcagc aaacttcggg gggcggcggc ggcaactcca ccgcggcggc ggccggcggc 180aaccagaaaa acagcccgga ccgcgtcaag cggcccatga atgccttcat ggtgtggtcc 240cgcgggcagc ggcgcaagat ggcccaggag aaccccaaga tgcacaactc ggagatcagc 300aagcgcctgg gcgccgagtg gaaacttttg tcggagacgg agaagcggcc gttcatcgac 360
gaggctaagc ggctgcgagc gctgcacatg aaggagcacc cggattataa ataccggccc 420cggcggaaaa ccaagacgct catgaagaag gataagtaca cgctgcccgg cgggctgctg 480gcccccggcg gcaatagcat ggcgagcggg gtcggggtgg gcgccggcct gggcgcgggc 540gtgaaccagc gcatggacag ttacgcgcac atgaacggct ggagcaacgg cagctacagc 600atgatgcagg accagctggg ctacccgcag cacccgggcc tcaatgcgca cggcgcagcg 660cagatgcagc ccatgcaccg ctacgacgtg agcgccctgc agtacaactc catgaccagc 720tcgcagacct acatgaacgg ctcgcccacc tacagcatgt cctactcgca gcagggcacc 780cctggcatgg ctcttggctc catgggttcg gtggtcaagt ccgaggccag ctccagcccc 840cctgtggtta cctcttcctc ccactccagg gcgccctgcc aggccgggga cctccgggac 900atgatcagca tgtatctccc cggcgccgag gtgccggaac ccgccgcccc cagcagactt 960cacatgtccc agcactacca gagcggcccg gtgcccggca cggccattaa cggcacactg1020cccctctcac acatgtgagg gccggacagc gaactggagg ggggagaaat tttcaaagaa1080aaacgaggga aatgggaggg gtgcaaaaga ggagagtaag aaacagcatg gagaaaaccc1140ggtacgctca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a1181<210>69<211>4729<212>DNA<213>人<400>69gctgctctcg ttcgcttggc tcagctcagc tcagctcagc gcagctccgc ggccgccaag 60ccgaggcggg cacggtctcc gagtcgcgga cgccagctcc gagctccctc tctccgccgc 120gcctccgcca ggtcgcgcct tcgtcgggac cacttcgggc aggagtcgcg tggcgaaggc 180ctgcggccgc ggcacaaagt tgggggccgc gaagatgagg ctgtccccgg cgcccctgaa 240gctgagccgg actccggcac tgctggccct ggcgctgccc ctggccgcgg cgctggcctt 300ctccgacgag accctggaca aagtgcccaa gtcagagggc tactgcagcc gtatcctgcg 360cgcccagggc acgcggcgcg agggctacac cgagttcagc ctccgcgtgg agggcgaccc 420cgacttctac aagccgggaa ccagctaccg cgtaacactt tcagctgctc ctccctccta 480cttcagagga ttcacattaa ttgccctcag agagaacaga gagggtgata aggaagaaga 540ccatgctggg accttccaga tcatagacga agaagaaact cagtttatga gcaattgccc 600tgttgcagtc actgaaagca ctccacggag gaggacccgg atccaggtgt tttggatagc 660accaccagcg ggaacaggct gcgtgattct gaaggccagc atcgtacaaa aacgcattat 720ttattttcaa gatgagggct ctctgaccaa gaaactttgt gaacaagatt ccacatttga 780tggggtgact gacaaaccca tcttagactg ctgtgcctgc ggaactgcca agtacagact 840cacattttat gggaattggt ccgagaagac acacccaaag gattaccctc gtcgggccaa 900ccactggtct gcgatcatcg gaggatccca ctccaagaat tatgtactgt gggaatatgg 960aggatatgcc agcgaaggcg tcaaacaagt tgcagaattg ggctcacccg tgaaaatgga1020
ggaagaaatt cgacaacaga gtgatgaggt cctcaccgtc atcaaagcca aagcccagtg1080gccagcctgg cagcctctca acgtgagagc agcaccttca gctgaatttt ccgtggacag1140aacgcgccat ttaatgtcct tcctgaccat gatgggccct agtcccgact ggaacgtagg1200cttatctgca gaagatctgt gcaccaagga atgtggctgg gtccagaagg tggtgcaaga1260cctgattccc tgggacgctg gcaccgacag cggggtgacc tatgagtcac ccaacaaacc1320caccattccc caggagaaaa tccggcccct gaccagcctg gaccatcctc agagtccttt1380ctatgaccca gagggtgggt ccatcactca agtagccaga gttgtcatcg agagaatcgc1440acggaagggt gaacaatgca atattgtacc tgacaatgtc gatgatattg tagctgacct1500ggctccagaa gagaaagatg aagatgacac ccctgaaacc tgcatctact ccaactggtc1560cccatggtcc gcctgcagct cctccacctg tgacaaaggc aagaggatgc gacagcgcat1620gctgaaagca cagctggacc tcagcgtccc ctgccctgac acccaggact tccagccctg1680catgggccct ggctgcagtg acgaagacgg ccccacctgc accatgtccg agtggatcac1740ctggtcgccc tgcagcatct cctgcggcat gggcatgagg tcccgggaga ggtatgtgaa1800gcagttcccg gaggacggct ccgtgtgcac gctgcccact gaggaaacgg agaagtgcac1860ggtcaacgag gagtgctctc ccagcagctg cctgatgacc gagtggggcg agtgggacga1920gtacagcgcc acctgcggca tgggcatgaa gaagcggcac cgcatgatca agatgaaccc1980cgcagatggc tccatgtgca aagccgagac atcacaggca gagaagcgca tgatgccaga2040gtgccacacc atcccatgct tgctgtcccc atggtccgag tggagtgact gcagcgtgac2100ctgcgggaag ggcatgcgaa cccgacagcg gatgctcaag tctctggcag aacttggaga2160ctgcaatgag gatctggagc aggtggagaa gtgcatgctc cctgaatgcc ccattgactg2220tgagctcacc gagtggtccc agtggtcgga atgtaacaag tcatgtggga aaggccacgt2280gattcgaacc cggatgatcc aaatggagcc tcagtttgga ggtgcaccct gcccagagac2340tgtgcagcga aaaaagtgcc gcatccgaaa atgccttcga aatccatcca tccaaaagct2400acgctggagg gaggcccgag agagccggcg gagtgagcag ctgaaggaag agtctgaagg2460ggagcagttc ccaggttgta ggatgcgccc atggacggcc tggtcagaat gcaccaaact2520gtgcggaggt ggaattcagg aacgttacat gactgtaaag aagagattca aaagctccca2580gtttaccagc tgcaaagaca agaaggagat cagagcatgc aatgttcatc cttgttagca2640agggtacgag ttccccaggg ctgcactcta gattccagag tcaccaatgg ctggattatt2700tgcttgttta agacaattta aattgtgtac gctagttttc atttttgcag tgtggttcgc2760ccagtagtct tgtggatgcc agagacatcc tttctgaata cttcttgatg ggtacaggct2820gagtggggcg ccctcacctc cagccagcct cttcctgcag aggagtagtg tcagccacct2880tgtactaagc tgaaacatgt ccctctggag cttccacctg gccagggagg acggagactt2940tgacctactc cacatggaga ggcaaccatg tctggaagtg actatgcctg agtcccaggg3000tgcggcaggt aggaaacatt cacagatgaa gacagcagat tccccacatt ctcatctttg3060
gcctgttcaa tgaaaccatt gtttgcccat ctcttcttag tggaacttta ggtctctttt3120caagtctcct cagtcatcaa tagttcctgg ggaaaaacag agctggtaga cttgaagagg3180agcattgatg ttgggtggct tttgttcttt cactgagaaa ttcggaatac atttgtctca3240cccctgatat tggttcctga tgccccccca acaaaaataa ataaataaat tatggctgct3300ttatttaaat ataaggtagc tagtttttac acctgagata aataataagc ttagagtgta3360tttttccctt gcttttgggg gttcagagga gtatgtacaa ttcttctggg aagccagcct3420tctgaacttt ttggtactaa atccttattg gaaccaagac aaaggaagca aaattggtct3480ctttagagac caatttgcct aaattttaaa atcttcctac acacatctag acgttcaagt3540ttgcaaatca gtttttagca agaaaacatt tttgctatac aaacattttg ctaagtctgc3600ccaaagcccc cccaatgcat tccttcaaca aaatacaatc tctgtacttt aaagttattt3660tagtcatgaa attttatatg cagagagaaa aagttaccga gacagaaaac aaatctaagg3720gaaaggaata ttatgggatt aagctgagca agcaattctg gtggaaagtc aaacctgtca3780gtgctccaca ccagggctgt ggtcctccca gacatgcata ggaatggcca caggtttaca3840ctgccttccc agcaattata agcacaccag attcagggag actgaccacc aagggatagt3900gtaaaaggac attttctcag ttgggtccat cagcagtttt tcttcctgca tttattgttg3960aaaactattg tttcatttct tcttttatag gccttattac tgcttaatcc aaatgtgtac4020cattggtgag acacatacaa tgctctgaat acactacgaa tttgtattaa acacatcaga4080atatttccaa atacaacata gtatagtcct gaatatgtac ttttaacaca agagagacta4140ttcaataaaa actcactggg tctttcatgt ctttaagcta agtaagtgtt cagaaggttc4200ttttttatat tgtcctccac ctccatcatt ttcaataaaa gatagggctt ttgctccctt4260gttcttggag ggaccattat tacatctctg aactaccttt gtatccaaca tgttttaaat4320ccttaaatga attgctttct cccaaaaaaa gcacagtata aagaaacaca agatttaatt4380atttttctac ttggggggaa aaaagtcctc atgtagaagc acccactttt gcaatgttgt4440tctaagctat ctatctaact ctcagcccat gataaagttc cttaagctgg tgattcctaa4500tcaaggacaa gccaccctag tgtctcatgt ttgtatttgg tcccagttgg gtacatttta4560aaatcctgat tttggagact taaaaccagg ttaatggcta agaatgggta acatgactct4620tgttggattg ttattttttg tttgcaatgg ggaatttata agaagcatca agtctctttc4680ttaccaaagt cttgttaggt ggtttatagt tcttttggct aacaaatca4729<210>70<211>443<212>DNA<213>人<400>70tttttttttt tttttccatt aacccaacac aagtttattt actaagtcaa gtcaaactga 60ggagtatttg tttctttggt agttggtaga caaagaatac atatacatat tctatttccc120attaagcatt cgatcatgtt acaaaacaat ggcctagaga actatcattg aagatttacc180
aaatctgcct gaagcaaaat gtgataaact gcagaaatgg tggagaatga cactggaagt 240cataaagttg attctcaaac acgggtttga actgcatagg accgcttata tgcatatttt 300gataaatata ttgaaaattt ttttggaaat ttgcaacaat ttaaaaaact tgcagatgca 360ccatgtagct tagaaatact gaaaaactaa gaaaaaggtg tgtcatgaat tcatataata 420tatgtagaca ctagtctatt tta 443<210>71<211>2432<212>DNA<213>人<400>71ggcgagtggc gagtggcgag tgtcaggggg gcggccggcg ggggcggggc ggccggagga 60ggcgttggca gcgggctcgg acccacgcgg cgccgcggcc cgcctggcct gcagcgctcc 120cacccccggc ggcggcacga tgccctttga cttcaggagg tttgacatct acaggaaggt 180gcccaaggac cttacgcagc caacgtacac cggggccatt atctccatct gctgctgcct 240cttcatcctc ttcctcttcc tctcggagct caccggattt ataacgacag aagttgtgaa 300cgagctctat gtcgatgacc cagacaagga cagcggtggc aagatcgacg tcagtctgaa 360catcagttta cccaatctgc actgcgagtt ggttgggctt gacattcagg atgagatggg 420caggcacgaa gtgggccaca tcgacaactc catgaagatc ccgctgaaca atggggcagg 480ctgccgcttc gaggggcagt tcagcatcaa caaggtcccc ggcaacttcc acgtgtccac 540acacagtgcc acagcccagc cacagaaccc agacatgacg catgtcatcc acaagctctc 600ctttggggac acgctacagg tccagaacat ccacggagct ttcaatgctc tcgggggagc 660agacagactc acctccaacc ccctggcctc ccacgactac atcctgaaga ttgtgcccac 720ggtttatgag gacaagagtg gcaagcagcg gtactcctac cagtacacgg tggccaacaa 780ggaatacgtc gcctacagcc acacgggccg catcatccct gcaatctggt tccgctacga 840cctcagcccc atcacggtca agtacacaga gagacggcag ccgctgtaca gattcatcac 900cacgatctgt gccatcattg gcgggacctt caccgtcgcc ggcatcctgg actcatgcat 960cttcacagcc tctgaggcct ggaagaagat ccagctgggc aagatgcatt gacgccacac1020ccagcctaat ggccgaggac cctgggcatc gccagccttg cctccagtgc cctgtctcct1080ttggccctca atctggtccc aaatctggct gtgtcccaaa gggtgtgtgg gaagtggggg1140gaaagtagag gatggctcga tgttttgcag ctacctcttt tccccgtgtt tctttttaga1200caaattacac tgcctgaagt tgcagttccc ctttccctgg ggagccccaa gaacagagtc1260aggcaagggg tggggagtcc agggatcttg gggacccctc ctaggagagc tgcagtctct1320tccctcaggg gaacatccca gaatgcatat cgatcagctc tcagccaggc ttcgacaatc1380tcgcagcccc cactaggtgg acacattaat gatttggttt ctcccctggg cagccaacct1440gccccagagg caccagacct gggctttcag ctttgggacc aggctgccca aaggtactcc1500tttatacacc cggcaccttc cacgaaagat ggtacttccc aagcaagccc ctatgatttg1560
tcactataga tggaaccctg acttctgccc catcccttcc tgcccaacct agaacccagg1620cctcaagtct ttaccccacc cctttcttgt tcttccaaga agcagatgcc cagttgctca1680gcagcagcgg tagagacttg aatctgccca ccagtcacaa ggcgggtcac agattcctct1740tcctctcttc tcctcgttcc tctgaaccct ccaccaatgt gcctcagcct gtgtgctgtg1800tggcaacagc attctggttc ccactgccaa gatctcccac cactctgctg ggatctgcag1860tggcagggag tgggggttgt gtaaagggga agtcatcttt tgagatccag atagacatgg1920tttgtgcact tacgtccaga tgggaagcat ccttcctgca accctaaaat aatcatgcag1980cctctcagac ggacgccatc ggtcccaagg ccttaggtgg aggaagcaaa gcaggccagg2040cctgtcctgt ccgtggacct ctaccttctg gactccctac gggtgcagag cacttgggtt2100tctctacagc catcgtggcc cacttgacac tgtgctcctc catcagctgg tcacatgcca2160acacgttccc agcccctgag gcagctccag ggtgccccac ctgctcctga ggtgggtccc2220taccctgctg ctcctcttca tcctttccct tttgtcctga aagggaggag caatggtcca2280ggcattaatt ccacccaggg aattttagct atgccctcat gtcccaggga gagagccaca2340cgcctgtttt ccatttatag caagattgtt tgcatacttt tgtaatgaag gggagtgtcc2400agtggaagga tttttaaaat tatcttatgg at 2432<210>72<211>2782<212>DNA<213>人<400>72gcggccgcgg cggggcggcg cgggaaccgg gccccggggg gagtcggccg ggctgctgct 60gctgctgctc caggtgctgc cgcccggggc tacggcaggg ccgggacgcc ggggcacgcg 120gggcgctggc ggcggcggcg tctgctggcc cggcgcggcc ccagcctttc cccgggacgc 180gcggctgctg ctgctcctgc cgccgctgcc gccactgtcg ccgccgccgc cgagctccgc 240gcccgcagcc tccgcctccc ggatggacgc tctgccccgc agcgggctga acctgaagga 300ggagccgctg ctgcccgccg gcctgggctc agtgcgctcc tggatgcagg gcgcgggcat 360cctggacgcc agcaccgcgg cgcagagtgg cgtgggtctg gcacgagcac attttgagaa 420gcagcctccc tccaacctca ggaaatccaa cttcttccac ttcgtgctgg ccatgtacga 480ccggcagggg cagcccgtgg aggtggagcg cacagccttc atcgacttcg tggaaaagga 540ccgagagccc ggggcggaaa agactaacaa tgggatccat taccgcctcc ggctggtgta 600taacaatgga ctgcggacag agcaagacct ctacgtgcgt ctcatcgact ccatgtccaa 660acaggccatc atctatgagg ggcaggacaa gaaccccgaa atgtgccgag tgctgctcac 720ccatgagatc atgtgcagcc ggtgctgtga ccggaagagc tgtggcaacc ggaatgagac 780gccctcagac cccgtcatca ttgacaggtt cttcctcaag ttcttcctca aatgcaacca 840gaactgcctg aagaatgcgg ggaatcccag agacatgcgc cgcttccagg tggtggtgtc 900cacgacggtg agcgtggacg gacacgtgct ggccgtgtcc gacaacatgt ttgtgcacaa 960
caactccaag catggccgca gggcgcgccg cctggacccc tccgaagctg ccaccccctg1020catcaaggcc atcagccccg gggagggctg gaccacgggc ggcgccaccg tcattgtcat1080cggcgacaac ttcttcgacg ggttgcaggt cgtgttcgga aacgtgctcg tgtggagcga1140gctcatcacg ccccacgcca tccgggtgca gacgcccccg cggcacatcc ccggggtggt1200ggaggtgacc ctctcctaca agtccaagca gttttgcaag ggatgccccg gccgctttgt1260ctacacagct ctgaacgagc ccaccattga ctacggattc cagaggctac agaaagtcat1320tcccagacac cccggagacc ccgagaggct gcccaaggaa gtgctgctga agcgggcggc1380cgacttggca gaagccctgt acggagtgcc cggcagtaac caggagctgc tcctgaagcg1440cgcggcggac gtggccgagg ctctgtacag caccccccgc gcacccgggc cgctcgcacc1500cctggccccg agccacccac actccgccgt cgtgggcatc aacgccttca gcagcccgct1560ggccatcgcc gtcggggacg ccaccccggg gcccgagccg ggctacgcgc gcagctgcag1620cagcgcgtcc ccccgcgggt tcgcgcccag ccccggctcg cagcagagcg gctacggcgg1680cggcctcgga gctggcctgg gcggctacgg cgcgccgggc gtggccggcc tcggcgtgcc1740tgggtccccc agcttcctca atggctccac cgccacctcg cccttcgcca aggagcgcct1800tcgcccccgt gctgcgcccc ccaagctccc caccccaggc ctgccccaga gcccacggag1860aggggcttcc agaccagtct tttgaggatt ctgacaagtt ccactctcca gcccgggggc1920ttcagggcct ggcatactcc taattacggt ctgcagctgt tcccatggag cccggactgg1980aggtccctct gggattcaca gccacacccc ggatggtggc acagacagat gcagggccag2040ggccatgggc ggacctcaac ccgtgagctg aacggggaga ggccttcacc ccatgctcaa2100gcctccccgc tagcagcccc acaggcttct ctcgcctccc tgtcttgggg tagtcagaag2160ccccagcact gtgcagatgc tcttggcagg acagcatcgc agggaggtgc tgggattctg2220ggcctcactg tctgggtctt ggttcctctg aaagagatgg atcttgtgca gaccagggtt2280gttgagtgag gggagcgtgg gatggggacc gtgggaaaga ggacagctca gggagaagtg2340acctggaaag gtcctgtttg catctgaccc atctcaactg gcccagcatc ccaacttctc2400tgcagcgaaa gggtggcgcc ccgcagcctc gggaggcctg cccaggctcc cgtggagctt2460ccaacagctg cttggccccg cagctgcccc cacttccttt gagacctgca ctctcatgct2520tgccgcatca tgcctccctg tgggggcttt gggcatggag gaggcagaag agggggtgcc2580aggcctcctg tatttggggt cttcccccag tggatgtctc atggactctg gccccacaca2640ctcacaatga ctctggctgg ccccacgcag cgggcccagc cgccccccag gtggcctcac2700attctgctct gctaagtttg gagaaaacag aacaataaac cagatgcagg tggtgcccgc2760ccggcctctc acctgcctcc tt 2782<210>73<211>1722<212>DNA<213>人<400>73
ggggaaaaga gctaggaaag agctgcaaag cagtgtgggc tttttccctt tttttgctcc 60ttttcattac ccctcctccg ttttcaccct tctccggact tcgcgtagaa cctgcgaatt 120tcgaagagga ggtggcaaag tgggagaaaa gaggtgttag ggtttggggt ttttttgttt 180ttgtttttgt tttttaattt cttgatttca acattttctc ccaccctctc ggctgcagcc 240aacgcctctt acctgttctg cggcgccgcg caccgctggc agctgagggt tagaaagcgg 300ggtgtatttt agattttaag caaaaatttt aaagataaat ccatttttct ctcccacccc 360caacgccatc tccactgcat ccgatctcat tatttcggtg gttgcttggg ggtgaacaat 420tttgtggctt tttttcccct ataattctga cccgctcagg cttgagggtt tctccggcct 480ccgctcactg cgtgcacctg gcgctgccct gcttccccca acctgttgca aggctttaat 540tcttgcaact gggacctgct cgcaggcacc ccagccctcc acctctctct acatttttgc 600aagtgtctgg gggagggcac ctgctctacc tgccagaaat tttaaaacaa aaacaaaaac 660aaaaaaatct ccgggggccc tcttggcccc tttatccctg cactctcgct ctcctgcccc 720accccgaggt aaagggggcg actaagagaa gatggtgttg ctcaccgcgg tcctcctgct 780gctggccgcc tatgcggggc cggcccagag cctgggctcc ttcgtgcact gcgagccctg 840cgacgagaaa gccctctcca tgtgcccccc cagccccctg ggctgcgagc tggtcaagga 900gccgggctgc ggctgctgca tgacctgcgc cctggccgag gggcagtcgt gcggcgtcta 960caccgagcgc tgcgcccagg ggctgcgctg cctcccccgg caggacgagg agaagccgct1020gcacgccctg ctgcacggcc gcggggtttg cctcaacgaa aagagctacc gcgagcaagt1080caagatcgag agagactccc gtgagcacga ggagcccacc acctctgaga tggccgagga1140gacctactcc cccaagatct tccggcccaa acacacccgc atctccgagc tgaaggctga1200agcagtgaag aaggaccgca gaaagaagct gacccagtcc aagtttgtcg ggggagccga1260gaacactgcc cacccccgga tcatctctgc acctgagatg agacaggagt ctgagcaggg1320cccctgccgc agacacatgg aggcttccct gcaggagctc aaagccagcc cacgcatggt1380gccccgtgct gtgtacctgc ccaattgtga ccgcaaagga ttctacaaga gaaagcagtg1440caaaccttcc cgtggccgca agcgtggcat ctgctggtgc gtggacaagt acgggatgaa1500gctgccaggc atggagtacg ttgacgggga ctttcagtgc cacaccttcg acagcagcaa1560cgttgagtga tgcgtccccc cccaaccttt ccctcacccc ctcccacccc cagccccgac1620tccagccagc gcctccctcc accccaggac gccactcatt tcatctcatt taagggaaaa1680atatatatct atctatttga ggaaaaaaaa aaaaaaaaaa aa 1722<210>74<211>2626<212>DNA<213>人<400>74gggtacggct gcgagaagac gacagaaggg gatgtcacct gctttatttc tggctttggc 60ctgtggtctg tgatacccat cctgcttgat gttctgcaga atggcacttg actgctgggc 120
atgcatgaag ttaagggcaa gaaacagtat gccatgtgtt ctgtaccatc atgtgtctct 180tcttgcttct gggcccttct actggtgaac tttcatcaag atctgcgcca tgccgtgtca 240ctatcaagcc attaagtttt gtctgggttg ctgtcagccc cagttggctt cctggtcaac 300aaggacctca agaactgcct gtggaccgag gccccctacc agtgcatgag acacacacct 360accctcccca gctttccagg aaccctactg gctgccagac tgatgggcgg gctggtatgt 420gtggacatgt gttcactgtc attatgctgt ggctccaggt gagggtgagg actgggccta 480tatagaatcc agataccatt gtcaacttcc cttattcccg tctaagatgt gagcagagtg 540ccatagtagg ggttctggga agaggtattt ctgatttgtg ggcctctgct tgcttgactt 600caggtcactt atacttctta ttttgcttgc ctgccttcat ccctcatttc ctccctctca 660ttcttctttc ctccctccct ttcctggtag cctcctttcc tccccttctg ccttcccctt 720ccttctttcc ttattctttt ttattttgtt taaatagtac cacagagaaa acaactgaaa 780aaccacattt ttctacatac agctggggag gtagctgaga acttggcact gcgcacacat 840actaggttga aagagagttg aggaaaccag aaggccaagt ggatctgctg gcaaaccctg 900aacctgtctc ctgcgcttgc tctacagttc tgaagttgaa aatcgttttc atgcctagca 960tctgcttgag ttataaaccc caaggcagcc atgtcataga ctagtgttta ctcttgtttt1020gactttgttt taatgcttcc taagacccaa gtgcctcctg ctgtttcctc ctttgtggta1080gcctctggcc atctggacct caatccccag ctttcccact ttcagcagtc ctttgctctc1140tttgcttcta cctcaaatag ccccaggagt gggctttagt ctccaatatg gagcatctca1200agcttctcct gggggatggg gattgggatg ggcggaatct gttttggatc tccgggttat1260ttccagtggg tgtaaaagca gagctgggcc tttccctctc ttatccctga gggtgggtaa1320gaaggactgt atctacacct gttcttccct accttctctt ttgttaggga ggcctcattc1380taagttcctc aagagagtcc ttggcttaaa gctgtagcaa gggtgtgcta ggtgggggat1440ttggagcaaa accgtcgagt aggcatgata ctggtatgga gtgggcctgc aaaatcagac1500agaaatggct tgagaagccg cagggggagc atgcctgtct ctcagtgata gagtatggga1560gggacctccc tagcttggaa aatgagaatt gaaggggtta tgaacaaata ggatgcctag1620ttgaggatgt tcccaaagtt ttgtccaatc ttatcattag tagattttat aagccacaga1680gacaaaccag aaacggaata atgttacttt ggatgcttta tttttttgtt ctaggtgtgg1740ctttgtacat gcagaagaat gctatatgct gcacattttg cctttaaagt cttacgactt1800tccccatttt agtctaatgg gaagatacag atgtgcaagt ctgctttttt gttttttgtt1860attatttttt tttttgctct gtgttatgga cattttcaga catgcacaga agtggagagg1920atggtccttg gaccccatgt gtccatcacc tagctgcatc acttatcagc tatggtcaac1980ctggtttcat ctgtatctct ctcttttcac ctgtattgtt tattgaaaat ccaagacact2040atgccaatgc aaccgtgact actttgggag attggtagtc tcttttgatg gtgatagtga2100tggggtgcac tatcataatc acatcaggtc tgctttttgc ttttaatgtt aactaatgaa2160gttccagaga tgggccttag aaatgtgttt taagaattaa caaggagtct caaaaagaaa2220
tgagagggat gcttcctttc ccttgcatct acaaaacaag agagagactg ttctgttgta2280aaactctttc aaaaattctg atatggtaag gtacttgaga cccttcacca gaatgtcaat2340ctttttttct gtgtaacatg gaaacttgtg tgaccattag cattgttatc agcttgtact2400ggtctcataa ctctggtttt ggaagaataa tttggaaatt gttgctgtgt tctgtgaaaa2460taacctcccc aaaataatta gtaactggtt gttctacttg gtaatttgac accctgttaa2520taacgcaatt atttctgtgt tcttaaacag tataaatagt tgtaagtttg catgcatgat2580ggaaaaataa aaacctgtat ctctgtcaaa aaaaaaaaaa aaaaaa 2626<210>75<211>3337<212>DNA<213>人<400>75gtcgagcctc tagcccgccc gggtttcctt cgcagtcgcg caccgacgct caaacgcgcg 60ctccaacccg cagcctcctc ctgcctcacc gcccgaagat ggcggctctc aaactcctct 120cctccgggct tcggctctgc gcctctgccc gcggatctgg ggcaacctgg tacaagggat 180gtgtttgttc cttttccacc agtgctcatc gccataccaa gttttataca gatccagtag 240aagctgtaaa agacatccct gatggtgcca cggttttggt tggtggtttt gggctatgtg 300gaattccaga gaatcttata gatgctttac tgaaaactgg agtaaaagga ctaactgcag 360tcagcaacaa tgcaggggtt gacaattttg gtttggggct tttgcttcgg tcgaagcaga 420taaaacgcat ggtctcttca tatgtgggag aaaatgcaga atttgaacga cagtacttat 480ctggtgaatt agaagtggag ctgacaccac agggcacact tgcagagagg atccgtgcag 540gcggggctgg agttcctgca ttttacaccc caacagggta tgggaccctg gtacaagaag 600gaggatcgcc catcaaatac aacaaagatg gcagtgttgc cattgccagt aagccaagag 660aggtgaggga gttcaatggt cagcacttta ttttggagga agcaattaca ggggattttg 720ctttggtgaa agcctggaag gcggaccgag caggaaacgt gattttcagg aaaagtgcaa 780ggaatttcaa cttgccaatg tgcaaagctg cagaaaccac agtggtagag gttgaagaaa 840ttgtggatat tggagcattt gctccagaag acatccatat tcctcagatt tatgtacatc 900gccttataaa gggagaaaaa tatgagaaaa gaattgagcg tttatcaatc cggaaagagg 960gagatgggga agccaaatct gctaaacctg gagatgacgt aagggaacga atcatcaaga1020gggccgctct tgagtttgag gatggcatgt atgctaattt gggcatagga atccctctcc1080tggccagcaa ttttatcagc ccaaatataa ctgttcatct tcaaagtgaa aatggagttc1140tgggtttggg tccatatcca cgacaacatg aagctgatgc agatctcatc aatgcaggca1200aggaaacagt tactattctt ccaggagcct cttttttctc cagcgatgaa tcatttgcaa1260tgattagagg tggacacgtc gatctgacaa tgctaggagc gatgcaggtt tccaaatatg1320gtgacctggc taactggatg atacctggga agatggtgaa aggaatggga ggtgctatgg1380atttagtgtc cagtgcgaaa accaaagtgg tggtcaccat ggagcattct gcaaagggaa1440
atgcacataa aatcatggag aaatgtacat taccattgac tggaaagcaa tgtgtcaacc1500gcattattac tgaaaaggct gtgtttgatg tggacaagaa gaaagggttg actctgattg1560agctctggga aggcctgaca gtggatgacg tacaaaagag tactgggtgt gattttgcag1620tttcaccaaa actcatgcca atgcagcaga tcgcaaattg aaatatggat atttgtacca1680ggctgcgtgt ttttcatttt aaacacacaa gatttaattg aaaggacatc aataatcata1740attgtgtatt taacaggtgg ttttttatta gttttcttgt gtttcagact ttatgcagcc1800atataaactg ttctctaggc atgctgtgac attttaataa aaagcaaaag gagcatttat1860aattatctca tttgttaagg ctgagaaggt tgtttttata ataggtaatt atattgaatg1920cattttcact gaatatggta tgtatgctaa attatatgaa cctttcccca agaagggccc1980tagaaattga tgtggctttc ctcttaaata ttaattatta gtcctgaaag aaagataaca2040tatgtgattt ttgtggttag gagagttgct gtcatgattg ttttttcttc agcctcctct2100gacttttctt ttggggcttc agattttatg attacatctt gtccccctag aacatccccc2160ttcctcccat actgctttta aacagatgcc caagaaggca agcaggaatg cctcttgtgg2220gggagggcag ggagaaataa ctagttcaaa ccaactatct atctatgctt tgcaaagact2280aaggcgtatt ataggaagag ggctagaaac ctaactgatt cttctcagtt ttctcatttt2340aaaacagccc agtattcctt tgtatcctca agggtccttg agaatacttc tgttattgaa2400accctgtggg ctacttgtac tgtacctcct ctcaagccaa gaagggctgt gggataattt2460accatgaatc cttagtagca atgacagcag agttaaaaaa taaaaggtgt tttactttca2520ggctcttgtt ttggttcaga ggagatttta aatattgaat gacacttcta cagaacaacg2580gtttttcttc tgccaaggct acttccttta acgaagtgcc tttaattcag ccttatccaa2640ctagggaaaa taatgttgga caagtctagg atttgaagag tcagtgaact tttagtgtca2700gggaataaac atggtgggta gattaggttt gaaaaaaact tccttagagg tatttattct2760caatacctga caggggccca tgggaatgac ttcagaagca tcccggataa tagatgggta2820aaaagtctag gcaccctgaa gaacaggtga gacagctggc ctctggacag aggtaggcat2880agtacagtac gatatatcat tcctctggtc ctaaatatac aaacttattc atgtttttag2940gtgatgatgg tcattgaaac tcacttcttt tcaggtgtag ctacaattgt gtaatgtaca3000atattagaga aaggacaggc tttttatgag taacacacac catatataaa acagcctttc3060tggctgacca catggttaaa tgcatacctt cccagtactg gggggaaaat gacccttctt3120agaatgtgca agttccatag agtaatatat tgatatgatt ttgaaaagaa ttgttgatag3180ttacatcttc aaacttatca ttccagtatg catctttaag ataatgtgat tctaagtaga3240tgactttata ttcttgatta aagagtgcta tacatgttaa gaaatgcatt aaggaataca3300ataaatattc taaactgatg aaaaaaaaaa aaaaaaa 3337<210>76<211>2460<212>DNA
<213>人<400>76aaagtcaaac cccgacaccg cggcgggccg gtgagctcac tagctgaccc ggcaggtcag 60gatctggctt agcggcgccg cgagctccag tgcgcgcacc cgtggccgcc tcccagccct 120ctttgccgga cgagctctgg gccgccacaa gactaaggaa tggccacccc gcccaagaga 180agctgcccgt ctttctcagc cagctctgag gggacccgca tcaagaaaat ctccatcgaa 240gggaacatcg ctgcagggaa gtcaacattt gtgaatatcc ttaaacaatt gtgtgaagat 300tgggaagtgg ttcctgaacc tgttgccaga tggtgcaatg ttcaaagtac tcaagatgaa 360tttgaggaac ttacaatgtc tcagaaaaat ggtgggaatg ttcttcagat gatgtatgag 420aaacctgaac gatggtcttt taccttccaa acatatgcct gtctcagtcg aataagagct 480cagcttgcct ctctgaatgg caagctcaaa gatgcagaga aacctgtatt attttttgaa 540cgatctgtgt atagtgacag gtatattttt gcatctaatt tgtatgaatc tgaatgcatg 600aatgagacag agtggacaat ttatcaagac tggcatgact ggatgaataa ccaatttggc 660caaagccttg aattggatgg aatcatttat cttcaagcca ctccagagac atgcttacat 720agaatatatt tacggggaag aaatgaagag caaggcattc ctcttgaata tttagagaag 780cttcattata aacatgaaag ctggctcctg cataggacac tgaaaaccaa cttcgattat 840cttcaagagg tgcctatctt aacactggat gttaatgaag actttaaaga caaatatgaa 900agtctggttg aaaaggtcaa agagtttttg agtactttgt gatcttgctg aagactacag 960gcagccaaat ggttccagat acttcagctt tgtgtatctt cgtaacttca tattaatata1020agtttcttta gaaaacccaa gtttttaatc gtttttgttt taaggaaaaa agatttttaa1080aatgaatctt atgcaaaact ttttgatcag tttcttttct tttgtttttt ttttaaaaaa1140gacatttaaa gacaaagaca ttatttctca tagcaggaaa tgtagaggta gatggttcca1200gtatcagcat agtgactaaa ctacattata aaagatccag cttccttctg tcattcccct1260cttttgtctt cctcagcagg ttggcttttt tccctggtgc ctctcacttc gttggtgacc1320agtttcttaa actgaaagct ttaatgttac atagtaaatg gtagtgtgtc ctgtgtaaat1380tagtgtacct attaaaagtt gcaaagtgga attaaaggaa tccctagaat aaggattctg1440aagttttatt ttaaattatt atcttcttaa cagtttagtc ccacctctta cttcctgcct1500cagtctgctt tctctactgt ctggattaat taggcagcct gctataaagt taaagtcaca1560catttctatt ttgcaaacac tgtgattact ctttgctttg tagtttgctt tgctttgtag1620ggttctgctt ttaagttttt ctctttttca gacaaattac tgataaaaat gatattgctc1680tatatgtaat atatcctgaa agcattattt tttgttgaat aggaaataaa attaatgaag1740acagaggcta gaaagcatcc attaattaat gagacacact taactactta tctctaaacc1800atctatgtga atatttgtaa aaataatgaa tggactcatc ttagttctgt atataaatat1860attttctttc tagtttgttt agttaaggtg tgcagtgttt ttcctgtgta ttaaaccttt1920ccattttacg ttttagaaaa ttttatgtat tttaaaataa ggggaagagt cattttcacc1980
tttaaactac tatttttctt tccaagtcat ttttgttttt ggtttcttat tcaaagatga 2040taatttagtg gattaaccag tccagacgca ctgatctttg caaaggagac ttaatttcaa 2100atctgtaatt accatacata aactgtctca ttatacgtat gcattttttt agtttgtttt 2160tgtttggtat aaattaattt gttaattaaa tatttcttaa gtataaacct tatgaactac 2220agtggagcta cactcattga aatgtaattt cagttctaaa aagatgtaat aatcatttta 2280gaattaaaat ttattctact tttaaataaa ttatgaatat taaaggtgaa aattgtataa 2340attactttga ttccatttta agtggagaca tatttcagtg atttttagta acctttaaaa 2400atgtataatg acttttaaaa tttgtagaat tgaaaagacg ctaataaaaa tttattattt 2460<210>77<211>7680<212>DNA<213>人<400>77gcggacactc ctctcggctc ctccccggca gcggcggcgg ctcggagcgg gctccggggc 60tcgggtgcag cggccagcgg gcctggcggc gaggattacc cggggaagtg gttgtctcct 120ggctggagcc gcgagacggg cgctcagggc gcggggccgg cggcggcgaa cgagaggacg 180gactctggcg gccgggtcgt tggccggggg agcgcgggca ccgggcgagc aggccgcgtc 240gcgctcacca tggtcagcta ctgggacacc ggggtcctgc tgtgcgcgct gctcagctgt 300ctgcttctca caggatctag ttcaggttca aaattaaaag atcctgaact gagtttaaaa 360ggcacccagc acatcatgca agcaggccag acactgcatc tccaatgcag gggggaagca 420gcccataaat ggtctttgcc tgaaatggtg agtaaggaaa gcgaaaggct gagcataact 480aaatctgcct gtggaagaaa tggcaaacaa ttctgcagta ctttaacctt gaacacagct 540caagcaaacc acactggctt ctacagctgc aaatatctag ctgtacctac ttcaaagaag 600aaggaaacag aatctgcaat ctatatattt attagtgata caggtagacc tttcgtagag 660atgtacagtg aaatccccga aattatacac atgactgaag gaagggagct cgtcattccc 720tgccgggtta cgtcacctaa catcactgtt actttaaaaa agtttccact tgacactttg 780atccctgatg gaaaacgcat aatctgggac agtagaaagg gcttcatcat atcaaatgca 840acgtacaaag aaatagggct tctgacctgt gaagcaacag tcaatgggca tttgtataag 900acaaactatc tcacacatcg acaaaccaat acaatcatag atgtccaaat aagcacacca 960cgcccagtca aattacttag aggccatact cttgtcctca attgtactgc taccactccc1020ttgaacacga gagttcaaat gacctggagt taccctgatg aaaaaaataa gagagcttcc1080gtaaggcgac gaattgacca aagcaattcc catgccaaca tattctacag tgttcttact1140attgacaaaa tgcagaacaa agacaaagga ctttatactt gtcgtgtaag gagtggacca1200tcattcaaat ctgttaacac ctcagtgcat atatatgata aagcattcat cactgtgaaa1260catcgaaaac agcaggtgct tgaaaccgta gctggcaagc ggtcttaccg gctctctatg1320aaagtgaagg catttccctc gccggaagtt gtatggttaa aagatgggtt acctgcgact1380
gagaaatctg ctcgctattt gactcgtggc tactcgttaa ttatcaagga cgtaactgaa1440gaggatgcag ggaattatac aatcttgctg agcataaaac agtcaaatgt gtttaaaaac1500ctcactgcca ctctaattgt caatgtgaaa ccccagattt acgaaaaggc cgtgtcatcg1560tttccagacc cggctctcta cccactgggc agcagacaaa tcctgacttg taccgcatat1620ggtatccctc aacctacaat caagtggttc tggcacccct gtaaccataa tcattccgaa1680gcaaggtgtg acttttgttc caataatgaa gagtccttta tcctggatgc tgacagcaac1740atgggaaaca gaattgagag catcactcag cgcatggcaa taatagaagg aaagaataag1800atggctagca ccttggttgt ggctgactct agaatttctg gaatctacat ttgcatagct1860tccaataaag ttgggactgt gggaagaaac ataagctttt atatcacaga tgtgccaaat1920gggtttcatg ttaacttgga aaaaatgccg acggaaggag aggacctgaa actgtcttgc1980acagttaaca agttcttata cagagacgtt acttggattt tactgcggac agttaataac2040agaacaatgc actacagtat tagcaagcaa aaaatggcca tcactaagga gcactccatc2100actcttaatc ttaccatcat gaatgtttcc ctgcaagatt caggcaccta tgcctgcaga2160gccaggaatg tatacacagg ggaagaaatc ctccagaaga aagaaattac aatcagagat2220caggaagcac catacctcct gcgaaacctc agtgatcaca cagtggccat cagcagttcc2280accactttag actgtcatgc taatggtgtc cccgagcctc agatcacttg gtttaaaaac2340aaccacaaaa tacaacaaga gcctggaatt attttaggac caggaagcag cacgctgttt2400attgaaagag tcacagaaga ggatgaaggt gtctatcact gcaaagccac caaccagaag2460ggctctgtgg aaagttcagc atacctcact gttcaaggaa cctcggacaa gtctaatctg2520gagctgatca ctctaacatg cacctgtgtg gctgcgactc tcttctggct cctattaacc2580ctccttatcc gaaaaatgaa aaggtcttct tctgaaataa agactgacta cctatcaatt2640ataatggacc cagatgaagt tcctttggat gagcagtgtg agcggctccc ttatgatgcc2700agcaagtggg agtttgcccg ggagagactt aaactgggca aatcacttgg aagaggggct2760tttggaaaag tggttcaagc atcagcattt ggcattaaga aatcacctac gtgccggact2820gtggctgtga aaatgctgaa agagggggcc acggccagcg agtacaaagc tctgatgact2880gagctaaaaa tcttgaccca cattggccac catctgaacg tggttaacct gctgggagcc2940tgcaccaagc aaggagggcc tctgatggtg attgttgaat actgcaaata tggaaatctc3000tccaactacc tcaagagcaa acgtgactta ttttttctca acaaggatgc agcactacac3060atggagccta agaaagaaaa aatggagcca ggcctggaac aaggcaagaa accaagacta3120gatagcgtca ccagcagcga aagctttgcg agctccggct ttcaggaaga taaaagtctg3180agtgatgttg aggaagagga ggattctgac ggtttctaca aggagcccat cactatggaa3240gatctgattt cttacagttt tcaagtggcc agaggcatgg agttcctgtc ttccagaaag3300tgcattcatc gggacctggc agcgagaaac attcttttat ctgagaacaa cgtggtgaag3360atttgtgatt ttggccttgc ccgggatatt tataagaacc ccgattatgt gagaaaagga3420gatactcgac ttcctctgaa atggatggct cccgaatcta tctttgacaa aatctacagc3480
accaagagcg acgtgtggtc ttacggagta ttgctgtggg aaatcttctc cttaggtggg3540tctccatacc caggagtaca aatggatgag gacttttgca gtcgcctgag ggaaggcatg3600aggatgagag ctcctgagta ctctactcct gaaatctatc agatcatgct ggactgctgg3660cacagagacc caaaagaaag gccaagattt gcagaacttg tggaaaaact aggtgatttg3720cttcaagcaa atgtacaaca ggatggtaaa gactacatcc caatcaatgc catactgaca3780ggaaatagtg ggtttacata ctcaactcct gccttctctg aggacttctt caaggaaagt3840atttcagctc cgaagtttaa ttcaggaagc tctgatgatg tcagatatgt aaatgctttc3900aagttcatga gcctggaaag aatcaaaacc tttgaagaac ttttaccgaa tgccacctcc3960atgtttgatg actaccaggg cgacagcagc actctgttgg cctctcccat gctgaagcgc4020ttcacctgga ctgacagcaa acccaaggcc tcgctcaaga ttgacttgag agtaaccagt4080aaaagtaagg agtcggggct gtctgatgtc agcaggccca gtttctgcca ttccagctgt4140gggcacgtca gcgaaggcaa gcgcaggttc acctacgacc acgctgagct ggaaaggaaa4200atcgcgtgct gctccccgcc cccagactac aactcggtgg tcctgtactc caccccaccc4260atctagagtt tgacacgaag ccttatttct agaagcacat gtgtatttat acccccagga4320aactagcttt tgccagtatt atgcatatat aagtttacac ctttatcttt ccatgggagc4380cagctgcttt ttgtgatttt tttaatagtg cttttttttt ttgactaaca agaatgtaac4440tccagataga gaaatagtga caagtgaaga acactactgc taaatcctca tgttactcag4500tgttagagaa atccttccta aacccaatga cttccctgct ccaacccccg ccacctcagg4560gcacgcagga ccagtttgat tgaggagctg cactgatcac ccaatgcatc acgtacccca4620ctgggccagc cctgcagccc aaaacccagg gcaacaagcc cgttagcccc aggggatcac4680tggctggcct gagcaacatc tcgggagtcc tctagcaggc ctaagacatg tgaggaggaa4740aaggaaaaaa agcaaaaagc aagggagaaa agagaaaccg ggagaaggca tgagaaagaa4800tttgagacgc accatgtggg cacggagggg gacggggctc agcaatgcca tttcagtggc4860ttcccagctc tgacccttct acatttgagg gcccagccag gagcagatgg acagcgatga4920ggggacattt tctggattct gggaggcaag aaaaggacaa atatcttttt tggaactaaa4980gcaaatttta gacctttacc tatggaagtg gttctatgtc cattctcatt cgtggcatgt5040tttgatttgt agcactgagg gtggcactca actctgagcc catacttttg gctcctctag5100taagatgcac tgaaaactta gccagagtta ggttgtctcc aggccatgat ggccttacac5160tgaaaatgtc acattctatt ttgggtatta atatatagtc cagacactta actcaatttc5220ttggtattat tctgttttgc acagttagtt gtgaaagaaa gctgagaaga atgaaaatgc5280agtcctgagg agagttttct ccatatcaaa acgagggctg atggaggaaa aaggtcaata5340aggtcaaggg aagaccccgt ctctatacca accaaaccaa ttcaccaaca cagttgggac5400ccaaaacaca ggaagtcagt cacgtttcct tttcatttaa tggggattcc actatctcac5460actaatctga aaggatgtgg aagagcatta gctggcgcat attaagcact ttaagctcct5520
tgagtaaaaa ggtggtatgt aatttatgca aggtatttct ccagttggga ctcaggatat5580tagttaatga gccatcacta gaagaaaagc ccattttcaa ctgctttgaa acttgcctgg5640ggtctgagca tgatgggaat agggagacag ggtaggaaag ggcgcctact cttcagggtc5700taaagatcaa gtgggccttg gatcgctaag ctggctctgt ttgatgctat ttatgcaagt5760tagggtctat gtatttagga tgcgcctact cttcagggtc taaagatcaa gtgggccttg5820gatcgctaag ctggctctgt ttgatgctat ttatgcaagt tagggtctat gtatttagga5880tgtctgcacc ttctgcagcc agtcagaagc tggagaggca acagtggatt gctgcttctt5940ggggagaaga gtatgcttcc ttttatccat gtaatttaac tgtagaacct gagctctaag6000taaccgaaga atgtatgcct ctgttcttat gtgccacatc cttgtttaaa ggctctctgt6060atgaagagat gggaccgtca tcagcacatt ccctagtgag cctactggct cctggcagcg6120gcttttgtgg aagactcact agccagaaga gaggagtggg acagtcctct ccaccaagat6180ctaaatccaa acaaaagcag gctagagcca gaagagagga caaatctttg ttgttcctct6240tctttacaca tacgcaaacc acctgtgaca gctggcaatt ttataaatca ggtaactgga6300aggaggttaa actcagaaaa aagaagacct cagtcaattc tctacttttt tttttttttt6360tccaaatcag ataatagccc agcaaatagt gataacaaat aaaaccttag ctgttcatgt6420cttgatttca ataattaatt cttaatcatt aagagaccat aataaatact ccttttcaag6480agaaaagcaa aaccattaga attgttactc agctccttca aactcaggtt tgtagcatac6540atgagtccat ccatcagtca aagaatggtt ccatctggag tcttaatgta gaaagaaaaa6600tggagacttg taataatgag ctagttacaa agtgcttgtt cattaaaata gcactgaaaa6660ttgaaacatg aattaactga taatattcca atcatttgcc atttatgaca aaaatggttg6720gcactaacaa agaacgagca cttcctttca gagtttctga gataatgtac gtggaacagt6780ctgggtggaa tggggctgaa accatgtgca agtctgtgtc ttgtcagtcc aagaagtgac6840accgagatgt taattttagg gacccgtgcc ttgtttccta gcccacaaga atgcaaacat6900caaacagata ctcgctagcc tcatttaaat tgattaaagg aggagtgcat ctttggccga6960cagtggtgta actgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgggtgtg7020ggtgtatgtg tgttttgtgc ataactattt aaggaaactg gaattttaaa gttactttta7080tacaaaccaa gaatatatgc tacagatata agacagacat ggtttggtcc tatatttcta7140gtcatgatga atgtattttg tataccatct tcatataata tacttaaaaa tatttcttaa7200ttgggatttg taatcgtacc aacttaattg ataaacttgg caactgcttt tatgttctgt7260ctccttccat aaatttttca aaatactaat tcaacaaaga aaaagctctt ttttttccta7320aaataaactc aaatttatcc ttgtttagag cagagaaaaa ttaagaaaaa ctttgaaatg7380gtctcaaaaa attgctaaat attttcaatg gaaaactaaa tgttagttta gctgattgta7440tggggttttc gaacctttca ctttttgttt gttttaccta tttcacaact gtgtaaattg7500ccaataattc ctgtccatga aaatgcaaat tatccagtgt agatatattt gaccatcacc7560ctatggatat tggctagttt tgcctttatt aagcaaattc atttcagcct gaatgtctgc7620
ctatatattc tctgctcttt gtattctcct ttgaacccgt taaaacatcc tgtggcactc7680<210>78<211>3160<212>DNA<213>人<400>78attctcgccg cgcccgggcg gacgatccag cgaacagccc cgcttctaac ccgagatgct 60gctgccggcg cccgcgctcc gccgcgccct gctgtcccgc ccctggaccg gggccggcct 120gcggtggaag cacacctcct ccctgaaggt ggccaacgag cccgtcttag ccttcacgca 180gggcagccct gagcgagatg ccctgcaaaa ggccttgaag gacctgaagg gccggatgga 240agccatccca tgcgtggtgg gggatgagga ggtgtggacg tcggacgtgc agtaccaagt 300gtcgcctttt aaccatggac ataaggtggc caagttctgt tatgcagaca agagcctgct 360caacaaagcc attgaggctg ccctggctgc ccggaaagag tgggacctga agcctattgc 420agaccgggcc cagatcttcc tgaaggcggc agacatgctg agtgggccgc gcagggctga 480gatcctcgcc aagaccatgg tgggacaggg taagaccgtg atccaagcgg agattgacgc 540tgcagcggaa ctcatcgact tcttccggtt caatgccaag tatgcggtgg agctggaggg 600gcagcagccc atcagcgtgc ccccgagcac caacagcacg gtgtaccggg gtctggaggg 660cttcgtggcg gccatctcgc cctttaactt cactgcaatc ggcggcaacc tggcgggggc 720accggccctg atgggcaacg tggtcctatg gaagcccagt gacactgcca tgctggccag 780ctatgctgtc taccgcatcc ttcgggaggc tggcctgccc cccaacatca tccagtttgt 840gccagctgat gggcccctat ttggggacac tgtcaccagc tcagagcacc tctgtggcat 900caacttcaca ggcagtgtgc ccaccttcaa acacctgtgg aagcaggtgg cccagaacct 960ggaccggttc cacaccttcc cacgcctggc tggagagtgc ggcggaaaga acttccactt1020cgtgcaccgc tcggccgacg tggagagcgt ggtgagcggg accctccgct cagccttcga1080gtacggtggc cagaagtgtt ccgcctgctc gcgtctctac gtgccgcact cgctgtggcc1140gcagatcaaa gggcggctgc tggaggagca cagtcggatc aaagtgggcg accctgcaga1200ggattttggg accttcttct ctgcagtgat tgatgccaag tcctttgccc gtatcaagaa1260gtggctggag cacgcgcgct cctcgcccag cctcaccatc ctggctgggg gcaagtgtga1320tgactccgtg ggctactttg tggagccctg catcgtggag agcaaggacc ctcaggagcc1380catcatgaag gaggagatct tcgggcctgt actgtctgtg tacgtctacc cggacgacaa1440gtacaaggag acgctgcagc tggttgacag caccaccagc tatggcctca cgggggcagt1500gttctcccag gataaggacg tcgtgcagga ggccacaaag gtgctgagga atgctgccgg1560caacttctac atcaacgaca agtccactgg ctcgatagtg ggccagcagc cctttggggg1620ggcccgagcc tctggaacca atgacaagcc agggggccca cactacatcc tgcgctggac1680gtcgccgcag gtcatcaagg agacacataa gcccctgggg gactggagct acgcgtacat1740gcagtgagcc cctctcgggc tccaccgtcc agctgtctgt ccgtccaggt ggccgacctc1800
actgcacaga ccccactcca gcccctccac cccttcttca tgcacagctg cctttctata1860atccgggctt gactcccttc ttaccactgt attctggcct ctcccatgcc tcaggctctg1920gtttgagatc gtgctgggga ggaacatggc cactacccct tatcccatcg gccatgtggg1980aggtatgacc ctggtgcctg gcaggttctc cctctgccct ccactgggcc cagtggctca2040gggacctggg gaaaggagat ggagcagctc ttgggatcct ttggggaaaa ggaggccatt2100ctgggcccct tggcaaacct caccactcac agaggctcct ggccttgatc cctgcccctc2160caggtgtcca gggtaaagtg taactcagac tgacctgtgg ggcacagggg gcaccagctg2220gccttgccct ctctggtctg ggctgtctac cttcctcact gtatctttgc ccagacccac2280ctgggccagt aggcccctgt ccccagccac acaccttaga tgctggcatg ccttactcca2340ggtgcctgtg tttggccgag gcctgtgtga ttcccggtct gcaccacatg gcggggttgg2400ggggccgctg gaggccacct gccaaggcgt gggatgggat ggtcctgccg gtttaggccg2460tgattctgga aaaccttgga tgggccttcg tcctatgtca gccttccctt tgatcctcag2520gccctacctg tagagacctc cactcctaga gccagtctca gggtctggga tttccctgca2580ggagctcagc caccactgtg ccatggtgac acaggccaag gcagacattg gccctccctt2640ctcccagccc ccagaggcct ggccttgggt tcgtcagcat gggccgagga cgttgcctgt2700agaatcctcc tctgcctggg agtggctctg tgtggaccag tccctcactg gcccattctt2760tttttgacgc agccaatctg tgaccacgat tcctcccaca gatgcctcct gcttggattc2820tgagtggtca gagatctgta aagcatgact ttcaaggatg gttcttaggg gactgtgaaa2880gtgttgggtc ttcctccagg atgcctgcat gggaccccac ccggagctgg tgtggccatt2940ccccaagtgc cactggccca tggatggggg tgggtgctgg tgccagctgg gctgggtgtg3000ggttctgtgt ccttccagga tatgtgtcat ttcccatgag gggccggggc aggtggctgg3060gtgggggcac aggctggagt attcttagtt ctactggttc tacactgtga ggtggcaatg3120ggatttgctc agatgccacc caataaaatg cctgttactt 3160<210>79<211>1546<212>DNA<213>人<400>79cacggccgga gagacgcgga ggaggagaca tgagccggcg ggcgcccaga cggagcggcc 60gtgacgcttt cgcgctgcag ccgcgcgccc cgaccccgga gcgctgaccc ctggccccac 120gcagctccgc gcccgggccg gagagcgcaa ctcggcttcc agacccgccg cgcatgctgt 180ccccggactg agccgggcag ccagcctccc acggacgccc ggacggccgg ccggccagca 240gtgagcgagc ttccccgcac cggccaggcg cctcctgcac agcggctgcc gccccgcagc 300ccctgcgcca gcccggaggg cgcagcgctc gggaggagcc gcgcggggcg ctgatgccgc 360agggcgcgcc gcggagcgcc ccggagcagc agagtctgca gcagcagcag ccggcgagga 420gggagcagca gcagcggcgg cggcggcggc ggcggcggcg gaggcgcccg gtcccggccg 480
cgcggagcgg acatgtgcag gctgggctag gagccgccgc ctccctcccg cccagcgatg 540tattcagcgc cctccgcctg cacttgcctg tgtttacact tcctgctgct gtgcttccag 600gtacaggtgc tggttgccga ggagaacgtg gacttccgca tccacgtgga gaaccagacg 660cgggctcggg acgatgtgag ccgtaagcag ctgcggctgt accagctcta cagccggacc 720agtgggaaac acatccaggt cctgggccgc aggatcagtg cccgcggcga ggatggggac 780aagtatgccc agctcctagt ggagacagac accttcggta gtcaagtccg gatcaagggc 840aaggagacgg aattctacct gtgcatgaac cgcaaaggca agctcgtggg gaagcccgat 900ggcaccagca aggagtgtgt gttcatcgag aaggttctgg agaacaacta cacggccctg 960atgtcggcta agtactccgg ctggtacgtg ggcttcacca agaaggggcg gccgcggaag1020ggccccaaga cccgggagaa ccagcaggac gtgcatttca tgaagcgcta ccccaagggg1080cagccggagc ttcagaagcc cttcaagtac acgacggtga ccaagaggtc ccgtcggatc1140cggcccacac accctgccta ggccaccccg ccgcggcccc tcaggtcgcc ctggccacac1200tcacactccc agaaaactgc atcagaggaa tatttttaca tgaaaaataa ggaagaagct1260ctatttttgt acattgtgtt taaaagaaga caaaaactga accaaaactc ttggggggag1320gggtgataag gattttattg ttgacttgaa acccccgatg acaaaagact cacgcaaagg1380gactgtagtc aacccacagg tgcttgtctc tctctaggaa cagacaactc taaactcgtc1440cccagaggag gacttgaatg aggaaaccaa cactttgaga aaccaaagtc ctttttccca1500aaggttctga aaggaaaaaa aaaaaaaaac aaaaaaaaaa aaaaaa 1546<210>80<211>2819<212>DNA<213>人<400>80ctgggcccag ctcccccgag aggtggtcgg atcctctggg ctgctcggtc gatgcctgtg 60ccactgacgt ccaggcatga ggtggttcct gccctggacg ctggcagcag tgacagcagc 120agccgccagc accgtcctgg ccacggccct ctctccagcc cctacgacca tggactttac 180cccagctcca ctggaggaca cctcctcacg cccccaattc tgcaagtggc catgtgagtg 240cccgccatcc ccaccccgct gcccgctggg ggtcagcctc atcacagatg gctgtgagtg 300ctgtaagatg tgcgctcagc agcttgggga caactgcacg gaggctgcca tctgtgaccc 360ccaccggggc ctctactgtg actacagcgg ggaccgcccg aggtacgcaa taggagtgtg 420tgcacaggtg gtcggtgtgg gctgcgtcct ggatggggtg cgctacaaca acggccagtc 480cttccagcct aactgcaagt acaactgcac gtgcatcgac ggcgcggtgg gctgcacacc 540actgtgcctc cgagtgcgcc ccccgcgtct ctggtgcccc cacccgcggc gcgtgagcat 600acctggccac tgctgtgagc agtgggtatg tgaggacgac gccaagaggc cacgcaagac 660cgcaccccgt gacacaggag ccttcgatgc tgtgggtgag gtggaggcat ggcacaggaa 720ctgcatagcc tacacaagcc cctggagccc ttgctccacc agctgcggcc tgggggtctc 780
cactcggatc tccaatgtta acgcccagtg ctggcctgag caagagagcc gcctctgcaa 840cttgcggcca tgcgatgtgg acatccatac actcattaag gcagggaaga agtgtctggc 900tgtgtaccag ccagaggcat ccatgaactt cacacttgcg ggctgcatca gcacacgctc 960ctatcaaccc aagtactgtg gagtttgcat ggacaatagg tgctgcatcc cctacaagtc1020taagactatc gacgtgtcct tccagtgtcc tgatgggctt ggcttctccc gccaggtcct1080atggattaat gcctgcttct gtaacctgag ctgtaggaat cccaatgaca tctttgctga1140cttggaatcc taccctgact tctcagaaat tgccaactag gcaggcacaa atcttgggtc1200ttggggacta acccaatgcc tgtgaagcag tcagccctta tggccaataa cttttcacca1260atgagcctta gttaccctga tctggaccct tggcctccat ttctgtctct aaccattcaa1320atgacgcctg atggtgctgc tcaggcccat gctatgagtt ttctccttga tatcattcag1380catctactct aaagaaaaat gcctgtctct agctgttctg gactacaccc aagcctgatc1440cagcctttcc aagtcactag aagtcctgct ggatcttgcc taaatcccaa gaaatggaat1500caggtagact tttaatatca ctaatttctt ctttagatgc caaaccacaa gactctttgg1560gtccattcag atgaatagat ggaatttgga acaatagaat aatctattat ttggagcctg1620ccaagaggta ctgtaatggg taattctgac gtcagcgcac caaaactatc ctgattccaa1680atatgtatgc acctcaaggt catcaaacat ttgccaagtg agttgaatag ttgcttaatt1740ttgattttta atggaaagtt gtatccatta acctgggcat tgttgaggtt aagtttctct1800tcacccctac actgtgaagg gtacagatta ggtttgtccc agtcagaaat aaaatttgat1860aaacattcct gttgatggga aaagccccca gttaatactc cagagacagg gaaaggtcag1920cccgtttcag aaggaccaat tgactctcac actgaatcag ctgctgactg gcagggcttt1980gggcagttgg ccaggctctt ccttgaatct tctcccttgt cctgcttggg gttcatagga2040attggtaagg cctctggact ggcctgtctg gcccctgaga gtggtgccct ggaacactcc2100tctactctta cagagccttg agagacccag ctgcagacca tgccagaccc actgaaatga2160ccaagacagg ttcaggtagg ggtgtgggtc aaaccaagaa gtgggtgccc ttggtagcag2220cctggggtga cctctagagc tggaggctgt gggactccag gggcccccgt gttcaggaca2280catctattgc agagactcat ttcacagcct ttcgttctgc tgaccaaatg gccagttttc2340tggtaggaag atggaggttt accggttgtt tagaaacaga aatagactta ataaaggttt2400aaagctgaag aggttgaagc taaaaggaaa aggttgttgt taatgaatat caggctatta2460tttattgtat taggaaaata taatatttac tgttagaatt cttttattta gggccttttc2520tgtgccagac attgctctca gtgctttgca tgtattagct cactgaatct tcacgacaat2580gttgagaagt tcccattatt atttctgttc ttacaaatgt gaaacggaag ctcatagagg2640tgagaaaact caaccagagt cacccagttg gtgactggga aagttaggat tcagatcgaa2700attggactgt ctttataacc catattttcc ccctgttttt agagcttcca aatgtgtcag2760aataggaaaa cattgcaata aatggcttga ttttttaaaa aaaaaaaaaa aaaaaaaaa 2819
<210>81<211>2584<212>DNA<213>人<400>81tggcggcggc ggcggcggtt gtcccggctg tgccggttgg tgtggcccgt cagcccgcgt 60accacagcgc ccgggccgcg tcgagcccag tacagccaag ccgctgcggc cgggtccggc 120gcgggcggcg cgcgcagacg gagggcggcg gccgcggcca gggcggcccg tgggaccgcg 180ggcccccggc gcagcgctgc ccggctcccg gccctgccgg cctcctccct tggcgccgcg 240gccatggcgg ccagcgcgaa gcggaagcag gaggagaagc acctgaagat gctgcgggac 300atgaccggcc tcccgcgcaa ccgaaagtgc ttcgactgcg accagcgcgg ccccacctac 360gttaacatga cggtcggctc cttcgtgtgt acctcctgct ccggcagcct gcgaggatta 420aatccaccac acagggtgaa atctatctcc atgacaacat tcacacaaca ggaaattgaa 480ttcttacaaa aacatggaaa tgaagtctgt aaacagattt ggctaggatt atttgatgat 540agatcttcag caattccaga cttcagggat ccacaaaaag tgaaagagtt tctacaagaa 600aagtatgaaa agaaaagatg gtatgtcccg ccagaacaag ccaaagtcgt ggcatcagtt 660catgcatcta tttcagggtc ctctgccagt agcacaagca gcacacctga ggtcaaacca 720ctgaaatctc ttttagggga ttctgcacca acactgcact taaataaggg cacacctagt 780cagtccccag ttgtaggtcg ttctcaaggg cagcagcagg agaagaagca atttgacctt 840ttaagtgatc tcggctcaga catctttgct gctccagctc ctcagtcaac agctacagcc 900aattttgcta actttgcaca tttcaacagt catgcagctc agaattctgc aaatgcagat 960tttgcaaact ttgatgcatt tggacagtct agtggttcga gtaattttgg aggtttcccc1020acagcaagtc actctccttt tcagccccaa actacaggtg gaagtgctgc atcagtaaat1080gctaattttg ctcattttga taacttcccc aaatcctcca gtgctgattt tggaaccttc1140aatacttccc agagtcatca aacagcatca gctgttagta aagtttcaac gaacaaagct1200ggtttacaga ctgcagacaa atatgcagca cttgctaatt tagacaatat cttcagtgcc1260gggcaaggtg gtgatcaggg aagtggcttt gggaccacag gtaaagctcc tgttggttct1320gtggtttcag ttcccagtca gtcaagtgca tcttcagaca agtatgcagc tctggcagaa1380ctagacagcg ttttcagttc tgcagccacc tccagtaatg cgtatacttc cacaagtaat1440gctagcagca atgtttttgg aacagtgcca gtggttgctt ctgcacagac acagcctgct1500tcatcaagtg tgcctgctcc atttggacgt acgccttcca caaatccatt tgttgctgct1560gctggtcctt ctgtggcatc ttctacaaac ccatttcaga ccaatgccag aggagcaaca1620gcggcaacct ttggcactgc atccatgagc atgcccacgg gattcggcac tcctgctccc1680tacagtcttc ccaccagctt tagtggcagc tttcagcagc ctgcctttcc agcccaagca1740gctttccctc aacagacagc tttttctcaa cagcccaatg gtgcaggttt tgcagcattt1800ggacaaacaa agccagtagt aacccctttt ggtcaagttg cagctgctgg agtatctagt1860
aatcctttta tgactggtgc accaacagga caatttccaa caggaagctc atcaaccaat1920cctttcttat agccttatat agacaattta ctggaacgaa cttttatgtg gtcacattac1980atctctccac ctcttgcact gttgtcttgt ttcactgatc ttagctttaa acacaagaga2040agtctttaaa aagcctgcat tgtgtattaa acaccaggta atatgtgcaa aaccgagggc2100tccagtaaca ccttctaacc tgtgaattgg cagaaaaggg tagcggtatc atgtatatta2160aaattggcta atattaagtt attgcagata ccacattcat tatgctgcag tactgtacat2220atttttctta gaaattagct atttgtgcat atcagtattt gtaactttaa cacattgtta2280tgtgagaaat gttactgggg aaatagatca gccactttta aggtgctgtc atatatcttg2340gaatgaatga cctaaaatca ttttaaccat tgctactgga aagtaacaga gtcaaaattg2400gaaggtttta ttcattcttg aatttttcct ttctaaagag ctcttctatt tatacatgcc2460taaattcttt taaaatgtag agggatacct gtctgcataa taaagctgat catgttttgc2520tacagtttgc aggtgaaaaa aaataaatat tataaaataa aaaaaaaaaa aaagaaaaaa2580aaaa 2584<210>82<211>2115<212>DNA<213>人<400>82gaaatgaacc tctcttattg atttttattg gcctagagcc aggagtactg cattcagttg 60actttcaggg taaaaagaaa acagtcctgg ttgttgtcat cataaacata tggaccagtg 120tgatggtgaa atgagatgag gctccgcaat ggaactgtag ccactgcttt agcatttatc 180acttccttcc ttactttgtc ttggtatact acatggcaaa atgggaaaga aaaactgatt 240gcttatcaac gagaattcct tgctttgaaa gaacgtcttc gaatagctga acacagaatc 300tcacagcgct cttctgaatt aaatacgatt gtgcaacagt tcaagcgtgt aggagcagaa 360acaaatggaa gtaaggatgc gttgaataag ttttcagata ataccctaaa gctgttaaag 420gagttaacaa gcaaaaaatc tcttcaagtg ccaagtattt attatcattt gcctcattta 480ttgaaaaatg aaggaagtct tcaacctgct gtacagattg gcaacggaag aacaggagtt 540tcaatagtca tgggcattcc cacagtgaag agagaagtta aatcttacct catagaaact 600cttcattccc ttattgataa cctgtatcct gaagagaagt tggactgtgt tatagtagtc 660ttcataggag agacagatat tgattatgta catggtgttg tagccaacct ggagaaagaa 720ttttctaaag aaatcagttc tggcttggtg gaagtcatat caccccctga aagctattat 780cctgacttga caaacctaaa ggagacattt ggagactcca aagaaagagt aagatggaga 840acaaagcaaa acctagatta ctgttttcta atgatgtatg ctcaagaaaa gggcatatat 900tacattcagc ttgaagatga tattattgtc aaacaaaatt attttaatac cataaaaaat 960tttgcacttc aactttcttc tgaggaatgg atgattctag agttttccca gctgggcttc1020attggtaaaa tgtttcaagc gccggatctt actctgattg tagaattcat attcatgttt1080
tacaaggaga aacccattga ttggctcctg gaccatattc tctgggtgaa agtctgcaac1140cctgaaaaag atgcaaaaca ttgtgataga cagaaagcaa atctgcgaat tcgcttcaga1200ccttcccttt tccaacatgt tggtctgcac tcatcactat caggaaaaat ccaaaaactc1260acggataaag attatatgaa accattactt cttaaaatcc atgtaaaccc acctgcggag1320gtatctactt ccttgaaggt ctaccaaggg catacgctgg agaaaactta catgggagag1380gatttcttct gggctatcac accgatagct ggagactaca tcttgtttaa atttgataaa1440ccagtcaatg tagaaagtta tttgttccat agcggcaacc aagaacatcc tggagatatt1500ctgctaaaca caactgtgga agttttgcct tttaagagtg aaggtttgga aataagcaaa1560gaaaccaaag acaaacgatt agaagatggc tatttcagaa taggaaaatt tgagaatggt1620gttgcagaag gaatggtgga tccaagtctc aatcccattt cagcctttcg actttcagtt1680attcagaatt ctgctgtttg ggccattctt aatgagattc atattaaaaa agccaccaac1740tgatcatctg agaaaccaac acattttttc ctgtgaattt gttaattaaa gatagttaag1800catgtatctt ttttttattt ctacttgaac actacctctt gtgaagtcta ctgtagataa1860gacgattgtc atttccactt ggaaagtgaa tctcccataa taattgtatt tgtttgaaac1920taagctgtcc tcagatttta acttgactca aacatttttc aattatgaca gcctgttaat1980atgacttgta ctattttggt attatactaa tacataagag ttgtacatat tgttacattc2040tttaaatttg agaaaaacta atgttacata cattttatga agggggtact tttgaggttc2100acttatttta ctatt 2115<210>83<211>1635<212>DNA<213>人<400>83gggggtggcg gggacgcgag tggcggccgc ggggccccgg acaagggtcc gcagagctgc 60agccttcgag ggccagccct ctccgagtcc ggggctgggt cccaccagtg acaaggcggc 120agccccgcgc acaccaaaga gaaagcggct gtggcggcag cggcagcccc agccatgctg 180tgttatgtga cgaggccgga cgcggtgctg atggaggtgg aggtggaggc gaaagccaac 240ggcgaggact gcctcaacca ggtgtgcagg cgactgggaa tcatagaagt tgactatttt 300ggactgcaat ttacgggtag caaaggtgaa agtttatggc taaacctgag aaaccggatc 360tcccagcaga tggatgggct agccccttac aggcttaaac ttagagtcaa gttcttcgtg 420gagcctcatc tcatcttaca ggagcagact aggcatatct ttttcttgca catcaaggag 480gccctcttgg caggccacct cttgtgttcc ccagagcagg cagtggaact cagtgccctc 540ctggcccaga ccaagtttgg agactacaac cagaacactg ccaagtataa ctatgaggag 600ctctgtgcca aggagctctc ctctgccacc ttgaacagca ttgttgcaaa acataaggag 660ttggagggga ccagccaggc ttcagctgaa taccaagttt tgcagattgt gtcggcaatg 720gaaaactatg gcatagaatg gcattctgtg cgggatagcg aagggcagag actgctcatt 780
ggggttggac ctgaaggaat ctcaatttgt aaagatgact ttagcccaat taataggata 840gcttatcctg tggtgcagat ggccacccag tcaggaaaga atgtatattt gacggtcacc 900aaggaatctg ggaacagcat cgtgctcttg tttaaaatga tcagcaccag ggcggccagc 960gggctctacc gagcgataac agagacgcac gcattctaca ggtgtgacac agtgaccagc1020gccgtgatga tgcagtatag ccgtgacttg aagggccact tggcatctct gtttctgaat1080gaaaacatta accttggcaa gaaatatgtc tttgatatta aaagaacatc aaaggaggtg1140tatgaccatg ccaggagggc tctgtacaat gctggcgttg tggacctcgt ttcaagaagc1200aaccagagcc cttcacactc gcctctgaag tcctcagaaa gcagcatgaa ctgcagcagc1260tgcgagggcc tcagctgcca gcagacccgg gtgctgcagg agaagctacg caagctgaag1320gaagccatgc tgtgcatggt gtgctgcgag gaggagatca actccacctt ctgtccctgt1380ggccacactg tgtgctgtga gagctgcgcc gcccagctac agtcatgtcc cgtctgcagg1440tcgcgtgtgg agcatgtcca gcacgtctat ctgccaacgc acaccagtct tctcaatctg1500actgtaatct aatctgttgt gcttttgttg gacttggcat gtttccatga actgcactat1560tataaactat taaaatgata gatgttggag aaagtaatta ttccaacacc catctgccca1620tgcgatgtta aaaaa 1635<210>84<211>2118<212>DNA<213>人<400>84ctgtgaagat ggcgctctcc agggtgtgct gggctcggtc ggctgtgtgg ggctcggcag 60tcacccctgg acattttgtc acccggaggc tgcaacttgg tcgctctggc ctggcttggg120gggcccctcg gtcttcaaag cttcaccttt ctccaaaggc agatgtgaag aacttgatgt180cttatgtggt aaccaagaca aaagcgatta atgggaaata ccatcgtttc ttgggtcgtc240atttcccccg cttctatatc ctgtacacaa tcttcatgaa aggattgcag atgttatggg300ctgatgccaa aaaggctaga agaataaaga caaatatgtg gaagcacaat ataaagtttc360atcaacttcc ataccgggag atggagcatt tgagacagtt ccgccaagac gtcaccaagt420gtcttttcct aggtattatt tccattccac cttttgccaa ctacctggtc ttcttgctaa480tgtacctgtt tcccaggcaa ctactgatca ggcatttctg gaccccaaaa caacaaactg540atttcttaga tatctatcat gctttccgga agcagtccca cccagaaatt attagttatt600tagaaaaggt catccctctc atttctgatg caggactccg gtggcgtctg acagatctgt660gcaccaagat acagcgtggt acccacccag caatacatga tatcttggct ctgagagagt720gtttctctaa ccatcctctg ggcatgaacc aactccaggc tttgcacgtg aaagccttga780gccgggccat gcttctcaca tcttacctgc ctcctccctt gttgagacat cgtttgaaga840ctcatacaac tgtgattcac caactggaca aggctttggc aaagctgggg attggccagc900tgactgctca ggaagtaaaa tcggcttgtt atctccgtgg cctgaattct acgcatattg960
gtgaagatag gtgtcgaact tggctgggag aatggctgca gatttcctgc agcctgaaag1020aagctgagct gtctctcttg ctgcacaacg tggtcctgct ctccaccaac taccttggga1080caaggcgctg aatgaaccat ggagcggatg gcattgtcct gcagtcgtat agtatagcag1140tgcaggaaca aacagcactt gccagcaaag tctgtgtgta ctgttaagtg tgtgggaggc1200agagagagga gcaggggcca tgggcttcac agcatggcac acctgtggga actgcagaca1260ttcctctcac agctagaact gaaacaaacc ctcttgctag gggtggtccg tgtgaggtgt1320catcctgtcc ccctcataat tactaatagc tggaactggc agcagcctct actgggcttt1380tactgtgatg tgttcagttc atgtcctagg aagtcagctt ttgccccagg tgggaatcct1440tatttggctt aggactgatc cacttccatg ttacttacat ctgtgggttt ttgttgttgc1500tgttagaaaa tttttggctg gtgaaaacag cactcctttg gctggagcac ttgtgtccat1560gcatgtactt gggtgtttcc ctccatcctt tctgatatga ccaaaaatca agttgttttg1620ttttttgtca ccttcactgg catgggctaa ccacttcttt ttcaaaccct ctgaacacct1680ttttctgatg ggtaacttgc aggaatattc tattggaaaa gataacagga agtacaagtg1740cttcttgacc ccttcctcaa tgtttctagc cttcactctc cattgtcttt tctgggctgt1800attacagccc tctgtggatc ttcaactctg ctgcctccac tgtgatgcag cagtccaact1860gtaactgaca gtggctgcct tctctgggcc atggatcaca cctgtaaggt actaattact1920gcccagcctg gggagatcag gagaggtctg catagttagt aagttgggtt tagcttttgt1980gtgtgcatca gtgacttaga gttctgtaat aacttattgt aaatgcatga agcactgttt2040ttaaacccaa gtaaagactg cttgaaacct gttgatggaa aaaaaaaaaa aaaaaaaaaa2100aaaaaaaaaa aaaaaaaa 2118<210>85<211>4221<212>DNA<213>人<400>85cgataacgat ttgtgttgtg agaggcgcaa gctgcgattt ctgctgaact tggaggcatt 60tctacgactt ttctctcagc tgaggctttt cctccgaccc tgatgctctt caattcggtg 120ctccgccagc cccagcttgg cgtcctgaga aatggatggt cttcacaata ccctcttcaa 180tcccttctga ctggttatca gtgcagtggt aatgatgaac acacttctta tggagaaaca 240ggagtcccag ttcctccttt tggatgtacc ttctcttctg ctcccaatat ggaacatgta 300ctagcagttg ccaatgaaga aggctttgtt cgattgtata acacagaatc acaaagtttc 360agaaagaagt gcttcaaaga atggatggct cactggaatg ccgtctttga cctggcctgg 420gttcctggtg aacttaaact tgttacagca gcaggtgatc aaacagccaa attttgggac 480gtaaaagctg gtgagctgat tggaacatgc aaaggtcatc aatgcagcct caagtcagtt 540gccttttcta agtttgagaa agctgtattc tgtacgggtg gaagagatgg caacattatg 600gtctgggata ccaggtgcaa caaaaaagat gggttttata ggcaagtgaa tcaaatcagt 660
ggagctcaca atacctcaga caagcaaacc ccttcaaaac ccaagaagaa acagaattca 720aaaggacttg ctccttctgt ggatttccag caaagtgtta ctgtggtcct ctttcaagac 780gagaatacct tagtctcagc aggagctgtg gatgggataa tcaaagtatg ggatttacgt 840aagaattata ctgcttatcg acaagaaccc atagcatcca agtctttcct gtacccaggt 900agcagcactc gaaaacttgg atattcaagt ctgattttgg attccactgg ctctacttta 960tttgctaatt gcacagacga taacatctac atgtttaata tgactgggtt gaagacttct1020ccagtggcta ttttcaatgg acaccagaac tctacctttt atgtaaaatc cagccttagt1080ccagatgacc agtttttagt cagtggctca agtgatgaag ctgcctacat atggaaggtc1140tccacaccct ggcaacctcc tactgtgctc ctgggtcatt ctcaagaggt cacgtctgtg1200tgctggtgtc catctgactt cacaaagatt gctacctgtt ctgatgacaa tacactaaaa1260atctggcgct tgaatagagg cttagaggag aaaccaggag gtgataaact ttccacggtg1320ggttgggcct ctcagaagaa aaaagagtca agacctggcc tagtaacagt aacgagtagc1380cagagtactc ctgccaaagc ccccagggta aagtgcaatc catccaattc ttccccgtca1440tccgcagctt gtgccccaag ctgtgctgga gacctccctc ttccttcaaa tactcctacg1500ttctctatta aaacctctcc tgccaaggcc cggtctccca tcaacagaag aggctctgtc1560tcctccgtct ctcccaagcc accttcatct ttcaagatgt cgattagaaa ctgggtgacc1620cgaacacctt cctcatcacc acccatcact ccacctgctt cggagaccaa gatcatgtct1680ccgagaaaag cccttattcc tgtgagccag aagtcatccc aagcagaggc ttgctctgag1740tctagaaata gagtaaagag gaggctagac tcaagctgtc tggagagtgt gaaacaaaag1800tgtgtgaaga gttgtaactg tgtgactgag cttgatggcc aagttgaaaa tcttcatttg1860gatctgtgct gccttgctgg taaccaggaa gaccttagta aggactctct aggtcctacc1920aaatcaagca aaattgaagg agctggtacc agtatctcag agcctccgtc tcctatcagt1980ccgtatgctt cagaaagctg tggaacgcta cctcttcctt tgagaccttg tggagaaggg2040tctgaaatgg taggcaaaga gaatagttcc ccagagaata aaaactggtt gttggccatg2100gcagccaaac ggaaggctga gaatccatct ccacgaagtc cgtcatccca gacacccaat2160tccaggagac agagcggaaa gacattgcca agcccggtca ccatcacgcc cagctccatg2220aggaaaatct gcacatactt ccatagaaag tcccaggagg acttctgtgg tcctgaacac2280tcaacagaat tatagattct aatctgagtg agttactgag ctttggtcca ctaaaacaag2340ctgagctttg gtccactaaa acaagatgaa aaatacaaga gtgactctat aactctggtc2400tttaagaaag ctgccttttc atttttagac aaaatctttt caacgctgaa atgtacctaa2460tctggttcta ctaccataat gtatatgcag cttcccgagg atgaatgctg tgtttaaatt2520tcataaagta aatttgtcac tctagcattt tgaatgaata gtcttcactt tttaaattat2580tcatcttctc tataataatg acatcccagt tcatggaggc aaaaaacaag tttcttgtta2640tcctgaaact ttctatgctc agtggaaagt atctgccagc cacagcatga ggcctgtgaa2700ggctgactga gaaatcctct gctgaagacc cctggttctg ttctgcctcc aacatgtata2760
attttatttg aaatacataa tcttttcact atgcttttgt ggggtttttt ttaagtatgt2820gtaaaaatgt gatgctcaga taagtacatt tatatcagtt cagtgttaaa atgcagtctc2880ttgagttaaa gtcatcttta ttttaaatgc agtgataaat gtcaactctt cggagaaact2940aggagaacaa caacagaaag ctgtgtttgt cttttttctc tcaaatatat ctcccgtatg3000agatttcagg tccccatgtt ttcaccaagc aatctgctat gtcagccaac ccaacatcac3060tttctacagg aggttatgat ttttgccatt tactagagga agatgtttta tgaaatcaat3120ttggggtttg aattcaggtg cagtcatcag ttctttaggg gctgcaatgt tttaaaaaaa3180ataagtcatc agattttaag aaaaaagtga tgatttctta ttgatatttt tgtaacagaa3240tatagctctt aactgaaaat ccagaaccag aaacataaat cttgagtttc ttttcatgta3300cataaaaagc aatagccttt tagtatagat agccctgagc caaaaagtaa tagaattttc3360tctagatatt taatacagag agtgtataga ctgactctaa gttaataatg tgcaaaatat3420cttaaacatc cctcccctta ttcaacaatt atgtatcagt gatcttgaac cattgtttta3480tatttttcac ctttgtaacc tcatggaaag aggctttaca tactttctat gtactattta3540cttagaaggg agcccccttc cagtcatgaa acttcatttg ttttatccat atccctgagg3600actgtgtaga ctttatgtca gttctgtgta gactttatgt cagtttttgt cattatttga3660aaatctattc tgacaacttt ttaattcctt tgatcttata agttaaagct gtaacaactg3720aaattgcatg gatcaagtaa gcatagtttt atccagggag aaaaataaaa ggaagccata3780gaattgctct ggtcaaaacc aagcacacca tagccttaac tgaatattta ggaaatctgc3840ctaatctgct tatatttggt gtttgttttt tgactgttgg gctttgggaa gatgttattt3900atgaccaata tctgccagta acgctgttta tctcacttgc tttgaaagcc aatgggggaa3960aaaaatccat gaaaaaaaaa agattgataa agtagatgat tttgtttgta tccctaccca4020tctcctggca gccctactga gtgaaattgg gatacatttg gctgtcagaa attataccga4080gtctactggg tataacatgt ctcacttgga aagctagtac ttttaaatgg gtgccaaagg4140tcaactgtaa tgagataatt atccctgcct gtgtccatgt cagactttga gctgatcctg4200aataataaag ccttttacct t 4221<210>86<211>867<212>DNA<213>人<400>86cgtttcagcg tggcggcgct ggtgctggcg ttggccctgg aggacggccc cgagtgatgg 60ctggcgcctg cctcccgggt gtctcccggg tacagatgga gtcgtcccgc ggccgccggc 120ggcaaggtcg gcagctgcga ggccaagaga gaccccagga cacacacagc tgcctcccgg 180tgcgagaaga agaccccggc ttgagagtga gatggcgttt aatgattgct tcagtttgaa 240ctaccctggc aacccctgcc caggggactt gatcgaagtg ttccgtcctg gctatcagca 300ctgggccctg tacttgggtg atggttacgt tatcaacata gcacctgtag atggcattcc 360
tgcgtccttt acaagcgcca agtctgtatt cagcagtaag gccctggtga aaatgcagct420cttgaaggat gttgtgggaa atgacacata cagaataaac aataaatacg atgaaacgta480cccccctctc cctgtggaag aaatcataaa gcggtcagag tttgtaattg gacaggaggt540ggcctataac ttacttgtca acaactgtga acattttgtg acattgcttc gctatggaga600aggagtttca gagcaggcca accgagcgat aagtaccgtt gagtttgtga cagctgctgt660tggtgtcttc tcattcctgg gcttgtttcc aaaaggacaa agagcaaaat actattaaca720atttaccaaa gagatattga tattgaagga atttgggagg aggaaaagaa acctggggtg780aatacttatt ttcagtgcat cattactgtt ccagattcct atgatggatg gcagactctt840taataaattg cttactgata ttatctt867<210>87<211>561<212>DNA<213>人<220>
<221>misc_特征<222>(534)..(534)<223>任意碱基<400>87tttttttttc aaattttatt ttttgtactt ttattgaaaa ggtacattta aaaaaataca 60cagacatttt accatttaca ggttgcagat atagatgctc taaaagagtc cactctattt120tgttgttcta tgataactct tgcccctgat atcacaaaca ttccagtctt gttgatatcg180gcttaaaaag gggggcatgg gagcatgacc tgcaatatat tcagcgaaca gaaagacaaa240ttgttcaatt ataaattttt ttatcttctg tacattattg cattagggag ccacaaaatt300atgtagcatc attacaaatg aaaacaggtt aaaaatgaag aagatactta tatagaaata360catggattca ttgtcttctt gcagaatgca caagaggtgc aaaaatgtgc aatttaggaa420gctctttttc tgtttgtata cgtttgctta gcaacacaaa ccagtgagga agctacaaaa480taagttaaac aaaaatagca aacaggtagt aattatagct atgttatatg gctntctatt540tcatttaaat atctccaaat a 561<210>88<211>471<212>DNA<213>人<400>88tttcatgaat aattttattt ttattttggt catgactttt taaaattaat ggaaagtctc 60agtctgctca aatgataaac caaaaaatgg ggtcatgaag caaattcagt ctttgcattt120cttcaacaac caactcacat ttctctgctc cttgactcag aggctggaca tgtgctaaca180gcttttttgc ttctgtatat ccttaatagg atggcagaat cccggtgtta aaagaatctt240aaagtcagcc gtgtcaccat gggacctcga ttagcaaaca gatgtagaca ttccttccaa300
attcagtcaa agaaaaaact ctaataccag cagccatgtt cagggtgtgc acgacatgct360gagcgcttgg gatacatccc cttgtttaat tctcacagaa actttgtgag acaagtacta420taatccctgt ttaacagatg ggcaaactga ggtttggaaa aacactcattt 471<210>89<211>727<212>DNA<213>人<400>89taaaatatta ccttttattt tctcaggcac acaagtgatt tggataccaa ttatcaagac 60attttactga tttcccttta gaatgatcta ttttaaatct tcagccacct tagaaaaagt120ttgcagcaat cactttgcaa ttcataagta tcaggttaga atttagttgt ggaataagtt180aacagtttat gttcaatatg tgaggttatt tgaactcctg agttttaaat atcctgtgga240acagtgattc ctctcccttc taatggcttt tcagattaaa gcaatgactt taaaaagatt300acatcctaaa tacttgatta caacagaaat cgaccaatct aaaaatcaga tagtgttata360ctgaacatca ttctgatata atgagtagcc tctggctgaa acaaaattcc accaccaagg420ccatcaacca ggttagtact gtttttcctg gggtctatgt aaactctcct tttctctgca480aatgctgctt ggctgtgaac agcatggatt tacctgcacc aatgtggcac acacctagca540actttctcaa gcattctaaa gatatcccca gagctacaat attgacatat gcacagcact600ttctctagac agtccaatca gcgtgcacat cacacacaca gaatgctggg atatgctata660ctgcacactt agtacacagg tggaatagag tacaatgact aaagctcaca gaaaatgttt720tagtctt 727<210>90<211>460<212>DNA<213>人<400>90tttttgatat aaagggcttt tattttcttt acagttttct gtattttcca aatttctaca 60taaacataca cataaaagtc ataaaaatgt ccctcaaaat gacactccct ccaatgcagg120gagtgaggag gtgtgtgctg ggacgccaca gggtggctgc tgcagctaat ccctgtgcag180gtgcagccac tgctacactc cagcgtctga ggcccctctg cactggcagt gttagaatgg240ctgtctgaga gccaaggctg ttcacccgag cagagagtca tggagctggt acaggcagga300gccaaggtaa gcactaggct ggtgtgtgcc ctccaggggg caccctcctt gaagcaggcc360ctccaaggta ctcgccccct gaggcagccg ataacagccg gaagccttcc cctgggggga420cctggccatt tgtggagcag ggaaaggctc cactgccagt 460<210>91<211>392<212>DNA<213>人<400>91
tttttttttt tttttttgag ttgctgaaaa gtttactttt gagttttaaa ctgtactttg 60aaaactatat tgtgaactgt gttgacatga ggaaaggctg ggctccctga aaacatccag120ttccacagca gggcgggccc aagcccagcc aatccccagg caatgcaggg cagggatccc180acctggtata agtacgggca gagggcagag ccaggctgta tcgaggggcg gcgctgggac240cctcctcgcc cagaattcct actcatcccc agcacagaag tgctctgtag ggccagctga300ggacaccccg gttcactgag ggtggcccac agtaagtcgc cgtctggcag taagttagct360ctgcaggtgt ggaccccaag accacacacg gc 392<210>92<211>496<212>DNA<213>人<400>92ttttttgtat ttttctcaat ataatgttgc aagatgtcat tatattctca ttacccataa 60cttcccatcc aaatcttaat ggcacatttg atattttttc aaatggcttt gagatataat120tcacatacca cacaattcat gtatctaaag tatacagttc tgtagttctg tggttgttgg180ttacatccac cagactgagg gctccctgag ggttggtgcc tcagctttcc cttcacttac240tcattcacca aacattcagc gcctactgag tactggggtt atgatggcca acaggagaga300cagtctctgc ctactgtttg gtgggggtgg agtacttagt aaccgtcgtc attattgagt360gcttacctgt gctgggcaca gtgctgctac tgggtgactg tgtccccagg gctgtcccag420gctgggggtc tggaggagta gttatcagtt gaactgagtt aatccacagt ggaaggtaac480ccactccctg ccctag496<210>93<211>472<212>DNA<213>人<400>93ttaacacaaa agcttttact tggaaactgg caaatactgg actagaatac tgacatgctc 60acgctctggc gggagctcgg atgcagaagc tattgcacaa agcccctctg attgccttgc120tcctctttgg catgtatcag cagagcccca agggccaatt gcccacaggt ggggactgtt180ctccatcaag gtatggggac ccctacttcc ttgttttgtt aaaaagtgca ggtaggcgaa240gaaagcccag gcagttgacc cagtctttga aacagctgac tccccagagc tggggccagg300ggagcctggt cttgaggggt aagggctgca gggccaggct gatggcctgt gtcatggcat360tggccatctc ctctccagct tctcctcagc catcgcccgt ccgtcatggt ggtgtcggct420gcacctggac cttcctgcct ctccgctcag ggcagcagca gtgagtgcag ca472<210>94<211>585<212>DNA<213>人<400>94
tttttatatt atagtaaatt tatttggtat aattacatat taacattatt tacaatgcta 60atttttttat ttataaagta tctttatatg gacaaaaaga tacaaactgt tatcatttta120agtacaaagt atttctagaa atacattata agccattaaa aaaaaaaacg atatttcaag180attggttctt acatgctatg accaactcat atgaaagagc aagttgctcc cccttcattc240cttcccccaa ctccaaaggg aaaggaattt gatatttagg ctttaaaaaa tttcctacta300cctttatctt ttaaaaaacc ctactcaaaa caactatctc ttataaggga aaatatcata360gataagattt tcctttagaa aatgacatta aaagtggcat gagccctaga atgatatgtg420tattagaggc acttaaaaaa aatcagaagg gatccatagg aaggaattta attcagcaaa480tactgagtgt ccactgcatg caaggtaccc tgccagaaat ctcaaatgag taagttgtcc540ttagggatag aaggtgctaa gcatcatgca aaagatatga actga585<210>95<211>400<212>DNA<213>人<400>95ttattgtttt ttaaaaatac aattttgaaa tttattgttg aaaatggaca catggaacaa 60accaaacctt gttttatcat gtaattttca gaaaatatgt gatccataaa gattaaaaga120aagttgtatt aagtctggca gctttagtat taacttgaaa taaaatatgg caagctttcc180acgtcctcct ttatttccac aatccatatg tacgagctag attccagtca gaacttccac240aaatacttca ctctttggta gcagcggtta taaattacgc ctttgctaat ttgcgttgtt300cccaaccagg agaaacatta ccacaaaaaa agtcagtttc atcctgcagt gttcccgcag360caaccatatt aaagctgaag aataaagctc ctttgtagta 400<210>96<211>461<212>DNA<213>人<400>96ttatgccatg aattcctttt tactgaaata ccgtaggact cactaccaca ataagtactt 60aagctgaaag agtttctaat gggagccaag taaattcagc tctccactgt gcaaagcatc120ttgtcatttc tataataaaa gtctttccat gttcagtcca ctttggctct ggaacctgga180tgagtcatgc ttggggccca gggtgcctgt gaggatgctg catgagaatt tcagctgtgg240tggcagtggc tgggagtccc actgactcag ggggaggcca ggcgagatga gctggaactt300ttaggggaga gctggcactt agggacatca ttgattgtgc ttttcttagc ctagttctgt360cctgcaattt atttttctta tcatgtgact gtcggctgaa gtctggggtt atttggtttc420tttttcttct tccttgctgg acagtctcca tggggtcacg g461<210>97<211>542<212>DNA<213>人
<400>97taaatccagt aaagcatagt actagattca tcatacttgt acaatacaac gggcgacatg 60aaaatggcaa aggctctcct ttttgtgaac aatttaatac aactggtggt ccaataactc120tacaatcagc cttgtagagg tcattaaaga cagaatcctg aaagtccgtg actacaaata180cattttcaaa ttccggagaa tccaaacctt caaattcttc cactgactcc atctttacaa240agcccacttt aatgtccttt aaggctttta taagttcttc ttgttttcca gcttcttgaa300ccaatatcac tcttgtttca atctgaggca tctcttcttc tacatatgaa gtagatccaa360taagtaagtt ttccttggaa atctcagtaa ctttagaatc aaaaatggaa gagtctgcca420agctagtcct cccagtagtg gatgttaata cactattttc agccatgatt tgtattcttc480taaatcagca ctctcaaaaa agccctagga gttccacctc ttcaaacgcc gactcctctc540ac 542<210>98<211>1017<212>DNA<213>人<400>98atgggcacct ggcttctggc ctgcacctgc gtctgcacct gtgtctgctc gggagtctct 60gtctcagggg atggacgagg gccaagggct ggaacctcca cctgcctcac caacaacatt120ctcaggattg attgccactg gtctgcccca gagctgggtc agggctccag ccccgggctc180cccttcatca gccccgtggt gctgacacat gcccttttca gcaaccaggc tgctggtggc240acacagaagt gcatctggca gggcagtgag tgcactgtag tgttgccgcc caaggcagca300ctcctgccat ctgacaattt catcatcact ttctaccact gcatgtccgg gagggatcag360agcacgtcag ctcgccactg catcctgacc tggagcctca gtcctgcctt ggagtcaatg420accacacttc tcagctatga gctggacttc aagaggcagg aagaggcctg ggagcgggcc480cagcacaggg atcacattgt cggggtgacc tggctcatac ttgaagcctt tgagctggac540cctggcttta tccttgaggc caggctgcgt gtccagacgg ccatgctggg ggatgacggg600gcacaggagg agcgagggga gccagcccat gggaagagtg aggcccagga gtgtggttca660cacaaggtcc ttcagcaggt gacacaaacc tccaaggccc atcacaaggt ccttcagcag720atgacacaaa cctccaaggc tcatcacaaa ccttccactt tggcccaggg cactaaaggg780cgcacttttg ccagccctgg gcccttcctg cccacggacc ctctgatccc accctggggg840tggccaggca acacctttgt tgctgtgtcc atctttctcc tgctgactgg cccgacctac900ctcctgttca agctgtcgcc cagactcctc actttgggca aaggacaaga agcaactcgg960atgggggccc acagggctgg tgtgctgctg agccaggact gtgctggcac ccgatga 1017<210>99<211>1099<212>DNA<213>人
<400>99agccccaagc ttaccacctg cacccggaga gctgtgtcac catgtgggtc ccggttgtct 60tcctcaccct gtccgtgacg tggattggtg agaggggcca tggttggggg gatgcaggag 120agggagccag ccctgactgt caagctgagg ctctttcccc cccaacccag caccccagcc 180cagacaggga gctgggctct tttctgtctc tcccagcccc actccaagcc cataccccca 240gcccctccat attgcaacag tcctcactcc cacaccaggt ccccgctccc tcccacttac 300cccagaactt tctccccatt gcccagccag ctccctgctc ccagctgctt tactaaaggg 360gaagttcctg ggcatctccg tgtttctctt tgtggggctc aaaacctcca aggacctctc 420tcaatgccat tggttccttg gaccgtatca ctggtccacc tcctgagccc ctcaatccta 480tcacagtcta ctgacttttc ccattcagct gtgagtgccc aaccctatcc cagagacctt 540gatgcttggc ctcccaatct tgccctagga tacccagatg ccaaccagac acctccttct 600tcctagccag gctatctggc ctgagacaac aaatgggtcc ctcagtctgg caatgggact 660ctgagaactc ctcattccct gactcttagc cccagactct tcattcagtg gcccacattt 720tccttaggaa aaacatgagc atccccagcc acaactgcca gctctctgat tccccaaatc 780tgcatccttt tcaaaaccta aaaacaaaaa gaaaaacaaa taaaacaaaa ccaactcaga 840ccagaactgt tttctcaacc tgggacttcc taaactttcc aaaaccttcc tcttccagca 900actgaacctc gccataaggc acttatccct ggttcctagc accccttatc ccctcagaat 960ccacaacttg taccaagttt cccttctccc agtccaagac cccaaatcac cacaaaggac1020ccaatcccca gactcaagat atggtctggg cgctgtcttg tgtctcctac cctgatccct1080gggttcaact ctgctccca 1099<210>100<211>1095<212>DNA<213>人<400>100ccaagcttac cacctgcacc cggagagctg tgtcaccatg tgggtcccgg ttgtcttcct 60caccctgtcc gtgacgtgga ttggtgagag gggccatggt tggggggatg caggagaggg 120agccagccct gactgtcaag ctgaggctct ttccccccca acccagcacc ccagcccaga 180cagggagctg ggctcttttc tgtctctccc agccccactt caagcccata cccccagccc 240ctccatattg caacagtcct cactcccaca ccaggtcccc gctccctccc acttacccca 300gaactttctc cccattgccc agccagctcc ctgctcccag ctgctttact aaaggggaag 360ttcctgggca tctccgtgtt tctctttgtg gggctcaaaa cctccaagga cctctctcaa 420tgccattggt tccttggacc gtatcactgg tccatctcct gagcccctca atcctatcac 480agtctactga cttttcccat tcagctgtga gtgtccaacc ctatcccaga gaccttgatg 540cttggcctcc caatcttgcc ctaggatacc cagatgccaa ccagacacct ccttcttcct 600agccaggcta tctggcctga gacaacaaat gggtccctca gtctggcaat gggactctga 660gaactcctca ttccctgact cttagcccca gactcttcat tcagtggccc acattttcct 720
taggaaaaac atgagcatcc ccagccacaa ctgccagctc tctgagtccc caaatctgca 780tccttttcaa aacctaaaaa caaaaagaaa aacaaataaa acaaaaccaa ctcagaccag 840aactgttttc tcaacctggg acttcctaaa ctttccaaaa ccttcctctt ccagcaactg 900aacctcgcca taaggcactt atccctggtt cctagcaccc cttatcccct cagaatccac 960aacttgtacc aagtttccct tctcccagtc caagacccca aatcaccaca aaggacccaa1020tccccagact caagatatgg tctgggcgct gtcttgtgtc tcctaccctg atccctgggt1080tcaactctgc tccca 109权利要求
1.一种选择在诊断应用中使用的标记物的框架的方法，包含a)定义诊断参数，b)建立一种诊断参数之间的关系以确定优化的标记物框架，c)选择上述的框架。
2.权利要求1的方法，其中标记物包含基因。
3.权利要求2的方法，其中关系是基于基因的表达。
4.权利要求2的方法，其中关系是基于基因的表达的方差。
5.权利要求4的方法，其中诊断参数包括基因的表达的相对程度值和在测定基因的表达的相对程度过程中的变化量；所述关系是均方差关系。
6.权利要求1的方法，进一步包含试探规则的应用。
7.权利要求1的方法，其中诊断参数是灵敏性和特异性。
8.包含一台通用计算机的、可程序化确定一种标记物框架的装置，其中，所述的装置包含执行诊断参数之间的关系以使得标记物被优化的指令。
9.权利要求8的装置，其中标记物包含基因。
10.权利要求9的装置，其中关系是基于基因的表达。
11.权利要求9的装置，其中关系是基于基因的表达的方差。
12.权利要求9的装置，其中所述指令包括测定基因的表达的相对程度值和测定在测定基因的表达的相对程度过程中的变化量；所述关系是均方差关系。
13.权利要求8的装置，进一步包含用于执行试探规则的指令。
14.权利要求8的装置，其中诊断参数是灵敏性和特异性。
15.一种包含选择用于诊断应用的标记物框架的指令的产品，包含a)输入诊断参数到一种算法的指令，b)运行上述的算法的指令，其中所述的算法与诊断参数有关，由此确定优化的标记物框架，和c)选择上述框架的指令。
16.权利要求15的产品，其中所述的标记物包含基因。
17.权利要求16的产品，其中关系是基于基因的表达。
18.权利要求17的产品，其中关系是基于基因的表达的方差。
19.权利要求17的产品，其中诊断参数包括基因的表达的相对程度值和在测定基因的表达的相对程度过程中的变化量；和所述关系是均方差关系。
20.权利要求16的产品，进一步包含用于执行试探规则的指令。
21.权利要求16的产品，其中诊断参数是灵敏性和特异性。
22.权利要求16的产品，其中指令是装置可读的。
23.权利要求22的产品，其中指令是计算机可读的。
24.按照权利要求1的方法选择的一个诊断框架。
25.权利要求24的框架，包含基因。
全文摘要
选择在诊断应用中使用的标记物框架的方法，包括定义诊断参数，确定这些参数之间的关系使得它们被优化，并选择优化的标记物在在诊断疾病中应用。这些诊断参数包括，基因表达的相对程度值，在测定基因的表达的相对程度过程中的变化量，和在诊断参数和区别参数之间的关系可以是均方差关系。本发明还进一步提供了包含操作指令的、可以程序化处理所述方法和产品的装置。
文档编号G01N33/48GK1495272SQ0313120
公开日2004年5月12日 申请日期2003年3月29日 优先权日2002年3月29日
发明者T·亚特克, T 亚特克 申请人:奥索临床诊断有限公司