1)deacetylase去乙酰化酶
1.The activity of deacetylases was measured with an ELISA-like reaction.方法应用细胞免疫荧光实验观察组蛋白乙酰化水平变化,并基于ELISA样反应方法检测组蛋白总体去乙酰化酶的活性变化,荧光定量PCR检测乙酰化酶mRNA表达,荧光定量PCR和Western印迹检测去乙酰化酶表达变化及曲古霉素A对相应酶表达的影响。
英文短句/例句
1.Histone deacetylases inhibitors anticancer drug:Vorinostat组蛋白去乙酰化酶抑制剂类抗癌药Vorinostat
2.The Design and Synthesis of Cyclic Tetrapeptide Histone Deacetylase Inhibitors;环肽类组蛋白去乙酰化酶抑制剂的设计与合成
3.Isolation and Functional Characterization of Rice Histone Deacetylase Gene;水稻组蛋白去乙酰化酶基因的分离和功能鉴定
4.Advances in the anticancer effect of histone deacetylase inhibitor组蛋白去乙酰化酶抑制剂抗肿瘤的研究进展
5.However, classical research methods which merely focus on single protein are still utilized to study acetyltransferase and deacetylase of Homo sapiens.目前对于乙酰化酶和去乙酰化酶的研究还基本上是传统的单个蛋白的研究方法。
6.Anticancer Activities of Histone Deacetylase and DNA Methyltransferase Inhibitors on Pancreatic Cancer;DNA甲基化酶和组蛋白去乙酰化酶抑制剂治疗胰腺癌的实验研究
7.Dynamic Changes of Histone Deacetylase 1 during Regulated Growth of Bronchial Stem Cells in Human Bronchial Regeneration;组蛋白去乙酰化酶1在气管干细胞增殖分化过程中的时空表达
8.Screening the in Vitro Anti-tumor Activities of Novel Synthetics Targeting to Histone Deacetylases靶向组蛋白去乙酰化酶新型化合物的体外抗肿瘤活性筛选
9.Molecular Mechanisms of Histone Deacetylase Inhibitors Induced Mitotic Catastrophe in Tumor Cells;组蛋白去乙酰化酶抑制剂诱导细胞有丝分裂灾变的分子机制探讨
10.Inhibition Effect of Histone Deacetylase Inhibitor FK228 on Prostate Cancer Cells;组蛋白去乙酰化酶抑制剂FK228对前列腺癌细胞的抑制作用
11.Express of HDAC6 in Primary Hepatocelluar Carcinoma and Its Clinical Significance;组蛋白去乙酰化酶6在原发性肝癌中的表达及临床意义
12.Histone Deacetylase Inhibitors of Polyoxometalates: Screening and Anti-Tumor Activity;多酸类组蛋白去乙酰化酶抑制剂的筛选及抗肿瘤活性研究
13.The Screening and Primary Functional Study of Histone Deacetylase Inhibitors from Polyoxometallates;多酸类组蛋白去乙酰化酶抑制剂的筛选及初步功能研究
14.Studies on Design、Synthesis and Activity of Hydroxamate Acids Derivatives as Histone Deacetylases Inhibitors;异羟肟酸类组蛋白去乙酰化酶抑制剂的设计合成与活性研究
15.The Establishment of Screening Models for Histone Deacetylase Inhibitors and Their Application in Screening of the Chinese Traditional Medicine Effective Components;组蛋白去乙酰化酶抑制剂筛选模型的建立及中药有效组分的筛选
16.The Effect of HDAC Inhibitor on Breast Cancer and ERα Expression;探讨组蛋白去乙酰化酶抑制剂对乳腺癌及ERα表达的影响
17.Role of Histone Deacetylase 1 in Pancreatic Cancer Cell Line: An Experimental Study;组蛋白去乙酰化酶1在胰腺癌发生机制中的作用研究
18.The Effect of Histone De-acetylase Inhibitor on RECK Gene Expression in Breast Cancer;组蛋白去乙酰化酶抑制剂对乳腺癌中RECK基因的表达影响研究
相关短句/例句
SIRT1 deacetylaseSIRT1去乙酰化酶
3)histone acetyltransferase (HAT)/histone deacetylase (HDACs)组蛋白乙酰化酶/组蛋白去乙酰化酶
4)deacetylation[di?,siti'lei??n]去乙酰化
1.Aim To investigate whether the mechanism of curcumin antagonizing tumor correlates with histone acetylation/deacetylation,which is regarded as modulation of transcription level.目的研究姜黄素对淋巴瘤细胞系Raji细胞的抑制增殖作用,并在组蛋白乙酰化/去乙酰化水平对其抗肿瘤机制进行探讨。
5)histone deacetylases组蛋白去乙酰化酶
1.Synthesis and activity study of a new series of histone deacetylases(HDACs) inhibitors of N-hydroxycinnamamide derivatives;一组新的N-羟基肉桂酰胺类组蛋白去乙酰化酶抑制剂的合成和初步活性研究
2.Histone acetyltransferases(HAT) and histone deacetylases(HDACs) as the corresponding enzymes regulate the change of histones in two antagonist forms,acetylated or deacetylated.组蛋白乙酰转移酶(HAT)和组蛋白去乙酰化酶(HDAC)调节组蛋白乙酰化程度,HDAC在基因表达和染色体形成等方面起着重要的调节作用。
3.Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are emerging as important components of protein complexes that affect the dynamics of chromatin folding during gene transcription.组蛋白乙酰转移酶(histone acetyltransferases, HATs)和组蛋白去乙酰化酶(histone deacetylase, HDACs)可以通过调节组蛋白或转录因子的乙酰化状态来调节基因的活化或沉默。
6)Histone deacetylase组蛋白去乙酰化酶
1.Differentiation of PLZF-RARα-positive U937 leukemic cells induced by histone deacetylase inhibitor trichostatin A in combination with all-trans retinoic acid;组蛋白去乙酰化酶抑制剂曲古菌素A联合全反式维甲酸诱导PLZF-RARα阳性U937细胞分化
2.Synergistic cytotoxicity effect of histone deacetylase inhibitor combined with paclitaxel on lung cancer cell lines and its mechanism组蛋白去乙酰化酶抑制剂协同紫杉醇对人肺癌细胞株抑制作用及机制
3.Relationship Between Systemic Inflammation and Activity of Histone Deacetylase in Peripheral Blood Mononuclear Cells from COPD Patients慢性阻塞性肺病外周血单个核细胞中的组蛋白去乙酰化酶活性与全身炎症的关系
延伸阅读
胆碱乙酰化酶分子式：CAS号：性质：又称胆碱乙酰基转移酶。一种酶，催化胆碱和乙酰辅酶A转变为乙酰胆碱和辅酶A。乙酰胆碱是重要的神经递质。溴乙酰辅酶A、氯乙酰胆碱等能抑制胆碱乙酰化酶。
