人骨保护素,Osteoprotegerin
1)Osteoprotegerin人骨保护素
1.To express human osteoprotegerin (OPG) in Pichia pastoris and determine its inhibitive effects on osteoclast differentiation and bone resorptive function in vitro .为了在毕赤酵母表达系统中分泌表达人骨保护素 (osteoprotegerin ,OPG) ,以人骨肉瘤细胞系MG6 3的mRNA为模板 ,采用RT PCR法得到人OPG编码区cDNA ,克隆入毕赤酵母表达载体pPICZ B ,电转化毕赤酵母GS115 (Mut+) ,经 3%甲醇诱导分泌表达人OPG与组氨酸的融合蛋白 。
英文短句/例句

1.Construction and Primary Expression of Human Osteoprotegerin in Mammalian Vectors;人骨保护素哺乳类表达载体的构建及初步表达
2.Inhibitory Effect of Plasmid Delivery of Osteoprotegerin on Alveolar Bone Resorption Resulting from Experimental Periodontitis in Rats;人骨保护素质粒转染抑制大鼠实验性牙周炎骨吸收的研究
3.Study of ex vivo OPG Gene Therapy in Preventing Wear Debris Induced Osteolysis;人骨保护素基因治疗抑制磨损颗粒诱导骨溶解的实验研究
4.The Efects of Recombinant Human Osteoprotegerin on the Osteoclasts Indueced by the Polyethylene Particles;重组人骨保护素对聚乙烯颗粒刺激破骨细胞功能的影响
5.The Experimental Study of Combination rhOPG-Fc and Alendronate on Inhibiting Osteoclasts and Treating Osteoporosis;联合应用重组人骨保护素和二膦酸盐抑制破骨细胞及治疗骨质疏松的实验研究
6.Construction, Optimization and Expression of Mammalia Recombinant Vector for Truncated Fragment of Human Osteoprotegerin截短型人骨保护素哺乳类载体的构建、优化及表达
7.Expression of truncated fragment of human OPG in CHO-DHFR~- cells and its bioactivity characterization截短型人骨保护素在CHO-DHFR~-细胞中的表达及活性测定
8.The Experimental Research of Human Osteoprotegerin Gene's Biologic Activity and the Prevention and Cure of Artificial Joint's Axenic Looseness;人骨保护素(hOPG)基因的生物活性及防治人工关节无菌性松动的实验研究
9.Expression of a Novo Human Osteoprotegerin-Mycobacterial Heat Shock 70 Fusion Protein with Baculovirus-Insect Expression System人骨保护素-热休克蛋白70融合蛋白在昆虫细胞中的表达和活性分析
10.Protection of Human Osteoprotegerin Mediated by Adeno-associated Virus on Bone Erosion in Collegen-induced Arthritis;腺相关病毒介导的人护骨素对炎症性关节破坏的保护作用
11.EFFECTS OF ESTROGEN INTERFERENCE ON PROLIFERATION OF HUMAN PERIODONTAL LIGAMENT CELLS AND OSTEOPROTEGERIN EXPRESSION雌激素干预对人牙周膜细胞增殖及骨保护素表达的作用
12.Effect of recombinant osteoprotegerin on glucocorticoid-induced osteoporosis in rats重组骨保护蛋白对糖皮质激素性骨质疏松的保护作用
13.A Study on the Expression of Osteoprotegerin during the Replacement of Dog s Primary and Permanent Teeth;犬乳恒牙替换期骨保护素表达的研究
14.Experimental Study of the Osteoprotegerin and the Ovariectomized Rat Model of Osteoporosis;骨保护素与去卵巢大鼠骨质疏松模型实验研究
15.Relationship between Serum Osteoprotegerin Level and Osteoporosis of Type 2 Ddiabetes Patients2型糖尿病患者骨保护素与骨质疏松的关系
16.Cloning, Recombinant Expression and Elementary Biological Activity of Human Osteoclastogenesis Inhibitory Factor/Osteoprotegerin;人破骨细胞形成抑制因子/骨保护素基因克隆、重组表达和初步的生物学活性研究
17.Protection effects of calcitonin on articular cartilage and subchondral bone of rat knee joint with osteoarthritis降钙素对OA大鼠关节软骨及软骨下骨的保护作用
18.OSTEOPROTEGRIN AND RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND mRNAs EXPRESSION IN BMSCs OF GLUCOCORTICOID-INDUCED NECROSIS OF THE FEMORAL HEAD PATIENTS激素性股骨头坏死BMSCs骨保护素/NF-κB受体活化因子配基mRNA的表达
相关短句/例句

osteoprotegerin(OPG)骨保护素
1.Objective:To study the expression of IL-10 at protein level in human dental follicle cells(HDFCs)and the effect of IL-10 on osteoprotegerin(OPG) secretion.目的:研究人牙囊细胞白细胞介素-10(IL-10)蛋白的表达及其对骨保护素(osteoprotegerin,OPG)表达的影响。
2.In addition,the Semiquantitative RT-PCR was using to assessed the regulation of dexamethasone(DEX)for Osteoprotegerin(OPG)or Ligand of receptor activator of nuclear factor kappa B(RANKL)in FRS.采用MTT掺入法检测细胞活率变化,分别筛选出诱导细胞增殖与凋亡的药物浓度;半定量PCR法检测不同浓度下地塞米松对骨保护素(Osteoprotegerin,OPG)和核因子κB受体激活剂受体配体(Ligand of receptor activator of nuclear factor kappa B,RANKL)基因在mRNA水平上的调控作用;流式细胞术检测细胞周期分布和凋亡率变化,显微镜观察FRSs存活、增殖和凋亡变化。
3.Objective To study the expression and significance of osteoprotegerin(OPG)in the development of dogs permanent teeth germs.目的:探讨犬乳恒牙替换过程中骨保护素在犬恒牙胚发育中的表达及意义。
3)osteoprotegerin骨保护素
1.Effect of advanced glycation end-products on the gene expression of osteoprotegerin in cultured rat vascular smooth muscle cells;糖基化终产物对大鼠血管平滑肌细胞骨保护素mRNA表达的影响
2.Effects of resveratrol on the expression of osteoprotegerin and receptor activator for NF-κB ligand in femurs of ovariectomized rats;白藜芦醇对去卵巢大鼠股骨骨保护素及核因子κB受体活化子配体表达的影响
3.The mechanism of osteoprotegerin on mineralization of enamel;骨保护素及其在釉质矿化中的作用机制
4)OPG骨保护素
1.Study of the PKA and PKC Signal Transduction Pathway of Regulation of OPG and RANKL mRNA Expression by hPTH(1-34);人甲状旁腺激素调节骨保护素及其配体基因表达的PKA、PKC信号传导通路研究
2.Effect of rhIGF-1 on the proliferation and differentiation and OPG,RANKL gene expression in rat osteoblast;rhIGF-1对成骨细胞增殖、分化及骨保护素、骨保护素配体基因mRNA表达的影响
3.Effects of cobalt and chromium ions on osteoblasts:cytotoxicity and the releasion of RANKL and OPG钴铬离子对成骨细胞细胞毒性及对其分泌骨保护素及其配体的影响
5)OPG骨保护素(OPG)
6)osteoprotegerin骨保护素(OPG)
延伸阅读

紫杉醇 ,紫素,特素,紫烷素,路泰,泰素药物名称:红豆杉醇英文名:Taxol别名: 红豆杉醇;紫杉醇 ,紫素,特素,紫烷素,路泰,泰素 外文名:Taxol ,TAX,Paclitaxel,PTX适应症: 本品适用于一线或其后的卵巢转移性癌化疗失败以后的治疗。 用量用法: 稀释的泰素注射液应先经过所连接的直径不超过0.22μm孔膜的滤过装置,使用前先用地噻米松、苯海拉明及H2一受体拮抗剂。 注意事项: 1.可有白细胞、血小板减少、贫血(血色素减少)、感染、粘膜炎、出血、过敏反应、低血压、心动过缓、心电图异常、关节痛、肌肉痛、转氨酶和胆红素升高、脱发、恶心及呕吐。 2.对本品有过敏者及骨髓抑制患者忌用。 规格: 浓缩注射液:30mg/支。 类别:抗肿瘤植物成分药