1)breast cancer resistance protein乳腺癌耐药蛋白
1.Expression of breast cancer resistance protein in normal human and tumor tissues;乳腺癌耐药蛋白在人体正常和肿瘤组织中的表达
2.The prognostic significance of breast cancer resistance protein (BCRP) expression in primary breast carcinoma;乳腺癌耐药蛋白在乳腺癌组织中的表达及其与预后的关系
3.The objective of this study was to investigate the relationship between the expressions of breast cancer resistance protein(BCRP)gene and drug resistance as well as prognosis in adult patients with acute lymphocytic leukemia(ALL).本研究探讨成人急性淋巴细胞白血病(ALL)患者乳腺癌耐药蛋白(BCRP)基因表达与临床耐药及预后的关系。
英文短句/例句
1.The Corelation between Syndrome Patterns of Traditional Chinese Medicine and P-glycoprotein (P-gp) and Breast Cancer Resistance Protein(BCRP);乳腺癌中医证型与跨膜糖蛋白（P-gp）、乳腺癌耐药蛋白（BCRP）相关性分析
2.Reversal multi-drug resistance by reducing the expression of CK8 and BCRP降低细胞膜角蛋白8和乳腺癌耐药蛋白的表达逆转耐药性
3.Establishment of Cell Line Highly Expressing BCRP and Investigation of Its Drug Resistant Mechanism;乳腺癌耐药蛋白高表达耐药细胞系的建立及其耐药机制
4.Interfering Breast Cancer Resistance Protein(BCRP) Gene for Reversing the Multidrug Resistance of Hepatocellular Carcinoma抑制乳腺癌耐药蛋白表达逆转肝细胞癌多药耐药
5.In Vivo Experimental Study on Reversion of Multidrug-resistance of Hepatocellular Carcinoma by Suppression of Breast Cancer Resistance Protein Gene抑制乳腺癌耐药蛋白基因逆转肝癌多药耐药的体内实验
6.The Clinical Research of Breast Cancer Resistance Protein Gene in Acute Myelocytic Leukemia;急性髓细胞白血病乳腺癌耐药蛋白的临床研究
7.Expression of Breast Cancer Resistance Protein Gene in Breast Cancer Patients and Its Value in Evaluating the Therapeutic Effect of Chemotherapy for Breast Cancer乳腺癌耐药蛋白基因在乳腺癌中的表达及其与化疗疗效的关系
8.Relation of expression of survivin and BCRP gene in prediction of response to chemotherapy in metastatic breast cancer生存素和乳腺癌耐药蛋白表达与转移性乳腺癌化疗效应的相关性
9.Transcriptional Regulation of Breast Cancer Resistance Protein (BCRP) by p53;p53对乳腺癌耐药蛋白（BCRP）的转录调控作用及机制
10.Clinical Significance of P-gp and BCRP Gene Expression in Acute Myeloblastic Leukemia;P-糖蛋白与乳腺癌耐药蛋白基因在急性髓系白血病中表达的意义
11.The Clinical and Biological Significance of Breast Cancer Resistance Protein Expression in Acute Leukemia;乳腺癌耐药蛋白在急性白血病中的表达及其意义
12.The significance of Bcl-2 and BCRP gene expression in elderly patients with acute myeloid leukemiaBcl-2与乳腺癌耐药蛋白基因在老年急性髓系白血病中表达的意义
13.Transcriptional Modulation of Breast Cancer Resistance Protein by Estrogen and Antiestrogen in Breast Carcinoma Cells;雌激素及其拮抗剂调节乳腺癌耐药蛋白机制的研究
14.Expression of Some Multidrug Resistant Gene and Protein in Breast Cancer Cases部分耐药基因和蛋白在乳腺癌病例中的表达
15.Advance on Three Drug Resistance Proteins(BCRP,LRP and TS)乳腺癌中三种耐药蛋白(BCRP,LRP和TS)的研究进展
16.Expression and Clinical Significance of Lung Resistance Protein in Breast Cancer肺耐药蛋白在乳腺癌中的表达及临床意义
17.Expression and Clinical Significance of Multidrug Resistance Gene MDR1 and P-gp, C-erbB-2 Protein in Breast Cancer;多药耐药基因MDR1及P-gp、C-erbB-2蛋白在乳腺癌中的表达及临床意义
18.The clinical significance of drug resistance-associated protein (DRP) expression in primary breast carcinoma乳腺癌组织中四种耐药相关蛋白的表达及其临床意义
相关短句/例句
BCRP乳腺癌耐药蛋白
1.Recently,researches are focussed on the MDR,including P-glycoprotein(Pgp),multidrug resistance-associated protein(MRP),lung resistance-asspcoated protein(LRP),topoisomerase II(TopoII)and breast cancer resistance protein(BCRP).目前,P-糖蛋白(P-glycoprotein,Pgp)、多药耐药相关蛋白(multidrug resistance-associated protein,MRP)、肺耐药相关蛋白(lung re-sistance-associated protein,LRP)、拓扑异构酶II(topoisomeraseII,TopoII)及乳腺癌耐药蛋白(breast cancer resist-ance protein,BCRP),已成为人们研究的热点。
2.Objective To explore the function of BCRP in ovary cancer and establisment of BCRP expressing ovary cancer cell line 3AO/BCRP.目的探讨乳腺癌耐药蛋白(BCRP)在卵巢癌中的作用和逆转其介导的MDR,建立表达BCRP的耐药细胞系3AO/BCRP。
3.Objective: To investigate the suppression of BCRP gene and protein by small interfering RNA (siRNA) and the restoration of sensitivity to chemotherapeutic drugs in multidrug-resistant hepatocellular carcinoma cell line HepG2/ADM.目的:研究小片段RNA干扰对肝癌耐药细胞系HepG2/ADM中乳腺癌耐药蛋白(BCRP)基因及其产物表达的抑制作用和逆转其耐药性的效果。
3)breast cancer resistance protein(BCRP)乳腺癌耐药蛋白
1.The expression of breast cancer resistance protein(BCRP) in primary breast carcinoma and its clinical impact;乳腺癌耐药蛋白在癌组织中的表达及临床意义
2.Objective The aim of present study was to investigate the expression of breast cancer resistance protein(BCRP) in primary breast carcinoma and its potential significance of guiding breast carcinoma chemotherapy and to determine whether such expression can predict survival.目的:研究乳腺癌耐药蛋白BCRP在乳腺癌组织中的表达以及它在乳腺癌化疗指导中的潜在意义,评估其在判断乳腺癌化疗敏感性中的作用。
4)Breast cancer resistance protein gene乳腺癌耐药蛋白基因
5)breast cancer resistance protein (BCRP)乳腺癌耐药蛋白(BCRP)
1.Transcriptional Regulation of Breast Cancer Resistance Protein (BCRP) by p53;p53对乳腺癌耐药蛋白（BCRP）的转录调控作用及机制
6)breast cancer resistance protein乳腺癌耐药相关蛋白
1.Breast cancer resistance protein(BCRP/ABCG2) belongs to the ATP-binding cassette(ABC) transporter superfamily.乳腺癌耐药相关蛋白(BCRP/ABCG2)属于ATP结合盒(Adenosine triphosphate-binding cassette,ABC)膜转运蛋白超家族。
2.Objective To study the correlation of the expression of breast cancer resistance protein(BCRP)with clinical index and pathological parameters such as estrogen receptor(ER),progestogen receptor(PR),HER-2 and P53 in breast cancer.目的探讨原发性乳腺癌中乳腺癌耐药相关蛋白(BCRP)表达与临床指标及病理参数的相关性。
延伸阅读
乳腺癌乳腺癌breast，cancerof乳房的恶性肿瘤。发病率在中国占全身各种恶性肿瘤的7％～10％，在妇女仅次于宫颈癌。发病年龄以40～60岁居多数，其中又以45～49岁(更年期)和60～64岁为最多。发病原因与性激素变化有很大关系。临床表现：最早的表现为患者侧乳房出现无痛、单发的小肿块，质硬，表面不光滑，与周围组织分界不很清楚，因此无自觉症状，常在洗澡、更衣时无意中发现。癌块增长的速度较快，随其体积增大，侵及周围组织后，在乳房内不易推动，进一步可引起乳房外形改变，如癌块表面皮肤凹陷、乳头牵向癌块方向、乳头内陷等，为重要乳腺癌体征。癌块继续增长，因皮内和皮下淋巴管被癌细胞阻塞引起局部淋巴水肿，故表面皮肤呈暗红色。癌块发展至晚期可侵入胸肋膜、胸肌，以致癌块固定于胸壁而不易推动，并出现疼痛症状，有时皮肤破溃形成溃疡或呈菜花状。乳腺癌的转移途径为淋巴转移，晚期也可有血行转移，最初转移至腋窝淋巴结，先为散在，数目少，质硬无痛，可推动，以后数目增多，互相粘连成团，甚至与皮肤和深部组织粘连。按疾病严重程度分为4期：第一期，癌瘤完全局限于乳房内，其直径＜3厘米，无淋巴结转移；第二期，癌瘤＜5厘米，同侧腋窝有数个散在而能推动的淋巴结；第三期，癌瘤直径＞5厘米，同侧腋窝有一连串融合成块的淋巴结；第四期，癌瘤广泛扩散至皮肤，或与胸肌、胸壁固定，广泛淋巴结转移或有远处转移。乳腺癌的预后：Ⅰ期5年治愈率90％左右，但此阶段应用现有的检查方法常常难以与乳房良性肿瘤区分，而活体组织切片检查则可以确诊。故强调开展普查，发现早期病例，或自己发现乳房有肿块时立即就诊。乳腺癌的治疗仍以早期手术治疗为主，辅以放射、激素、化学治疗等。浸润性乳腺癌
