O-烷基化,O-alkylation
1)O-alkylationO-烷基化
1.Ten open chain analogues with nitrogen or carbon as central atom (1a-e, 2a-e) were synthesized through O-alkylation of trithanoiamme, pentaerythritol and 4-hydroxy-antipyrine and S-alkylation of 2-mercaptobenzimidazole and 2-mercaptobenzothiazole with pentaerythrityltetrabromide.通过三乙醇胺、季戊四醇及4-羟基安替比林的O-烷基化和用季戊四溴对2-巯基苯并咪唑、2-巯基苯并噻唑的S-烷基化方法。
2.The O-alkylation of 2,5-dimethylphenol with 1,3-dihalogen- propane and some monohalogen carboxylic esters are studied.研究了2,5-二甲苯酚与1,3-二卤代丙烷及一卤代羧酸酯的O-烷基化反应。
2)O-dealkylationO-去烷基化
1.The N-, O-dealkylation metabolism of verapamil and naproxen via microbial transformation was studied in this paper, and the similarities and differences between fungi and humans were compared.本文以维拉帕米和萘普生两种药物为代表,探讨了微生物尤其是真菌在药物N-,O-去烷基化代谢研究中的应用,比较了真菌与人体在这两种药物代谢之间的异同,并制备了部分代谢物纯品;采用超速离心法制备了真菌微粒体,测定了其活性并研究了其对药物的转化能力,从亚细胞水平研究了真菌进行药物转化的机理;利用人体细胞色素P450酶的特异性底物及其相应的特异性化学抑制剂,探讨了真菌细胞内相关的药物转化酶与人体内药物代谢酶的异同。
英文短句/例句

1.Application of Microbial Transformation for Study on N-, O-Dealkylation of Drugs;微生物转化法在药物N-,O-去烷基化代谢研究中的应用
2.The Synthesis of a Series of O-Substituted Hydroxylamines;一系列O-取代烷基羟胺化合物的合成
3.Enzymatic Synthesis of 1-O-glycyl-3-O-tetradecanylglycerol酶催化1-O-甘氨酰-3-O-十四烷酰化甘油的合成
4.STUDY ON SYNTHESIS AND TRIBOLOGICAL PROPERTIES OF A MULTIFUNCTIONAL NOVEL 2-MERCAPTOBENZOTHIAZOL DERIVATIVES-(2-巯基苯并噻唑)O,O′-二烷基二硫代磷酸酯的合成及性能研究
5.O-or N-alkylation was carried out directly by simple heating the mixture of carboxylic acid or amine with quaternary ammonium salt.将羧酸或胺类化合物与季铵盐进行简单的混合加热,便可直接得到o-或n-烷基化产物。
6.Preparation of Mo-V-Te-Nb-O Catalyst for the Selective Oxidation of Propane to Acrylic Acid丙烷选择氧化制备丙烯酸Mo-V-Te-Nb-O催化剂
7.The Study on Ni/Ce-M-O (M=Zr or Ti) for Partial Oxidation of Methane;Ni/Ce-M-O(M=Zr或Ti)用于甲烷部分氧化的研究
8.acid-spending strength废酸浓度(烷基化)
9.The Study of Continuous Synthesis Technology of O, O-dimethyl Phosphoroamidothioate;O,O-二甲基硫代磷酰胺连续化合成新工艺研究
10.Study on Ni-V-O/oxide Catalysts for Oxidative Dehydrogenation of Propane to Propylene;丙烷氧化脱氢制丙烯Ni-V-O/氧化物催化剂的研究
11.Study on RE/Ni-V-O Composite Oxide Catalysts for Oxidative Dehydrogenation of Propane to Propene;丙烷氧化脱氢制丙烯RE/Ni-V-O复合氧化物催化剂的研究
12.Solid Phase Extraction-Silyl Derivation-Gas Chromatography-Mass Spectrometry for the Analysis of Atrazine and Its N-Desalkalated Metabolites in Urine固相萃取-硅烷化-气质联用分析尿中莠去津及其去烃基代谢物
13.Investigation of the Technology for the Preparation of Methyl N-tert-butoxyl-carbonyl-O-alkyl-L-tyrosinateN-叔丁氧酰基-O-烷基-L-酪氨酸甲酯的合成工艺研究
14.Synthesis of N,N′-Di-(2,3,4-Tri-O-Acetyl)-Diamino-Diphenyl-Methane GlucosideN,N′-二(2,3,4-三-O-乙酰基)葡萄糖二氨基二苯甲烷苷的合成
15.Preparation, Characterization and Property of New Precursors of V-P-O Catalyst for n-Butane Oxidation to Maleic Anhydride;正丁烷氧化制顺酐V-P-O催化剂新前驱物合成、表征及性能
16.The Research of La-Ni-O Catalysts on Partial Oxidation of Methane to Syngas;La-Ni-O系催化剂用于甲烷部分氧化制合成气的研究
17.The Study of Oxidative Dehydrogenation of Propane to Propene on Supported La-V-O Catalysts;负载型La-V-O催化剂上丙烷氧化脱氢制丙烯的研究
18.Study on the Catalytic Performance of La-Ni-O Catalysts for Partial Oxidation of Methane;甲烷部分氧化制合成气La-Ni-O系催化剂性能的研究
相关短句/例句

O-dealkylationO-去烷基化
1.The N-, O-dealkylation metabolism of verapamil and naproxen via microbial transformation was studied in this paper, and the similarities and differences between fungi and humans were compared.本文以维拉帕米和萘普生两种药物为代表,探讨了微生物尤其是真菌在药物N-,O-去烷基化代谢研究中的应用,比较了真菌与人体在这两种药物代谢之间的异同,并制备了部分代谢物纯品;采用超速离心法制备了真菌微粒体,测定了其活性并研究了其对药物的转化能力,从亚细胞水平研究了真菌进行药物转化的机理;利用人体细胞色素P450酶的特异性底物及其相应的特异性化学抑制剂,探讨了真菌细胞内相关的药物转化酶与人体内药物代谢酶的异同。
3)O-alkylO-烷基
4)O alkylation of chitosan壳聚糖的O烷基化
5)O-methylationO-甲基化
1.2% was synthesized from 4-chlorophenol by acylation,Fries rearrangement,O-methylation,oxidation.以间氯苯酚为原料,经乙酰化、Fries重排、O-甲基化和氧化反应合成了2-甲氧基-4-氯苯甲酸,总收率54。
2.This paper aimed to design a new synthetic route:starting from phenols,via acylation,Fries rearrangement,O-methylation,oxidation,getting corresponding alkoxy benzodic acids.本课题提出一条合成安息香酸的新路线,该合成路线以酚类物质为原料,通过醋酐乙酰化,Fries重排,O-甲基化,次氯酸钠氧化反应将羧基引入苯环,从而合成烷氧基安息香酸系列。
6)O-glycosylationO糖基化
1.Objective: To study the role of O-glycosylation in tumor formation, development and transfer, we constructed pGADT7/ppGalNAc-T2 vector in yeast two-hybrid system and detected its activation in this system.目的:为探讨O糖基化在肿瘤发生发展及转移中的作用,构建pGADT7/ppGalNAc T2载体,并转化酵母AH109进行激活检测。
延伸阅读

O-烷基化分子式:CAS号:性质:在分子中氧原子上引入烷基(R-)的反应过程。是合成醚类化合物的重要方法。