1)TacrolimusFK506
1.Central nervous system toxicity induced by tacrolimus after renal transplantation;肾移植术后应用FK506的神经毒性作用
2.Inhibitive effect of low-dose Tacrolimus on expression of inducible nitric oxide synthase and neuronal apoptosis in rats following contusion spinal cord injury;脊髓冲击伤后应用低剂量FK506抑制iNOS表达及神经细胞凋亡
3.The present study was aimed to evaluate whether the interindividual variation of tacrolimus dosage.目的探讨肝移植术后口服免疫抑制剂FK506的剂量及其全血谷浓度的个体差异与供体的肝药酶P450 3A5(CYP3A5)基因多态性的关系。
英文短句/例句
1.Inhibitory Effects of FK506 and 201A on Anti-GBM Nephritis in Rats;FK506和201A防治大鼠抗GBM肾炎的实验研究
2.Pharmacokinetics and Clinical Study of FK506 After Oral Administration in Patients after Renal Transplantation;FK506的药代动力学及临床研究
3.The Comparative Study of Treatment in Experimental Spinal Cord Injury by FTY720 with FK506;FTY720与FK506对脊髓损伤的治疗研究比较
4.The Experimental Study of FK506 Treating Acute Spinal Cord InjuryFK506治疗急性脊髓损伤的实验研究
5.The effect of FK506 on the early experimental membranous nephropathy ratsFK506治疗大鼠早期膜性肾病的实验研究
6.Analysis of FK506 Blood Concentration in 99 Patients with Liver Transplantation99例肝移植患者的FK506血药浓度分析
7.Effect of FK506 on injuried vascular wallFK506对损伤血管壁影响的电镜观察
8.Effects of CsA and FK506 on Serum Lipid and the Expression of CD36 after Renal Transplantation;CsA和FK506对肾移植术后血脂代谢和CD36表达的影响
9.Experimental Study of the Neuroprotective Effects of FK506 on Spinal Cord Injury in Dogs;FK506对犬急性脊髓损伤神经保护作用的实验研究
10.Experimental Study on Mechanism of Immunosuppressant FK506 to Accelerate Regeneration of Peripheral Nerves;免疫抑制剂FK506促周围神经再生机制的实验研究
11.Effect of p38 MAPK in Acute Rejection after Cardiac Transplantation and Inhibited by Tacrolimus;p38MAPK在心脏移植中的作用及FK506对p38MAPK的影响
12.Effects of FK506 on Liver Regeneration After Reduced-size Liver Transplantation in Rats;FK506对大鼠减体积肝移植后肝再生的影响
13.Experimental Study of FK506 in Combination with Neural Stem Cells on Nerve Regeneration after Nerve AllograftFK506及神经干细胞对异体神经移植作用的研究
14.Tacrolimus Enhances CXCR4/SDF-1α Expression and Promotes Hepatocellular Carcinoma MetastasisFK506促肝癌复发转移的研究及CXCR4/SDF1_α的相关性改变
15.An Dose-dependence Study of FK506 on Schwann Cells不同浓度FK506对雪旺细胞影响的实验研究
16.Effects of FK506 on acrylamide-induced peripheral nerve injuries of ratsFK506对丙烯酰胺致大鼠周围神经损伤的保护作用
17.Influence of genetic polymorphisms on the pharmacokinetics of tacrolimus in patients with organ transplantation基因多态性对器官移植患者FK506药动学的影响
18.Effect of FK506 on regulation of osteopontin expression and its relevant mechanism in diabetic ratFK506对糖尿病大鼠肾组织骨桥蛋白表达的影响
相关短句/例句
FK506 inhibitionFK506阻断
3)FK506-binding proteinFK506结合蛋白
4)tacrolimus(FK506)他克莫司(FK506)
5)Prograf (FK506)普乐可复(FK506)
6)Tacrolimus/FK506FK506/他可莫司
延伸阅读
FK-506分子式：CAS号：性质：筑波链霉菌Strep tomyces tsukubaensis产生的23元环的大环内酯族的免疫抑制剂。熔点127～129℃，旋光度-84.4°(c=1.02，三氯甲烷)。柱状结晶，具有高度脂溶性，极低水溶性。抑制抗体的产生和移植物的排斥作用及白细胞介素IL-2、IL-3和干扰素IFN-r的产生。体内的免疫抑制作用比环孢素强数倍，体外试验强100倍。用于心脏、肺脏移植有很好效果。肾脏移植效果较环孢素差，肾毒性比环孢素大。本品对某些曲菌和镰刀菌有抗真菌作用。
