强啡肽原,prodynorphin
1)prodynorphin强啡肽原
1.Objective: To observe the effect of chronic levodopa (L dopa) administration on striatal prodynorphin mRNA expression in a rat model of Parkinson disease (PD), and probe into the pathogenesis of L dopa induced dyskinesias (LID).目的 :观察左旋多巴 (L dopa)治疗对帕金森病 (PD )大鼠纹状体强啡肽原表达的影响 ,探讨L dopa诱发异动症 (LID)的机制。
2.Objective:To investigate the relationship between the Prodynorphin gene and the dopamine D_2 receptor gene and the susceptibility of schizophrenia in Chinese Han population and explore the effect of interaction of the two genes on the presence of schizophrenia.目的:探讨中国汉族人群强啡肽原(Prodynorphin,PDYN)基因和多巴胺D_2受体(dopamine D_2 receptor,DRD_2)基因与精神分裂症遗传易感性的关系及其相互作用对精神分裂症的影响。
英文短句/例句

1.Changes of Preprodynor phine mRNA and μOpioid Receptor in Morphine Dependent and Abstinent Rats;吗啡成瘾及戒断大鼠前强啡肽原mRNA与μ阿片受体的改变
2.Effect of Chronic L-DOPA Administration on Striatal Prodynorphin mRNA Expression in a Rat Model of Parkinson Disease左旋多巴治疗对帕金森病大鼠纹状体强啡肽原表达的影响
3.Association Analysis between the Prodynorphin Gene and the Dopamine D_2 Receptor Gene and Schizophrenia强啡肽原基因和多巴胺D_2受体基因与精神分裂症的关联分析
4.Expression of Proenkephalin Gene in NIH3T3 Cells;前脑啡肽原基因在NIH3T3细胞的表达
5.Stable expression of proenkephalin gene in NIH3T3 cellsNIH3T3细胞中前脑啡肽原基因的稳定表达
6.Electroacupuncture analgesia is enhanced in transgenic nociceptin/orphanin FQ knock-out mice孤啡肽基因敲除小鼠电针镇痛作用增强(英文)
7.Bovine Adrenal Medulla 8-22 Enhances Morphine Antinociception in Rats牛肾上腺髓质8-22肽增强吗啡的抗伤害作用
8.Morphological Study on the Connections between GABAergic,Dynorphinergic,Enkephalinergic Terminals adn the Mesencephalic Trigemincal Nucleus Neurons of the Rat;大鼠GABA能、脑啡肽能和强啡肽能终末与三叉神经中脑核神经元联系的形态学研究
9.It may also release brain endorphins, reducing sensitivity to pain and boosting endurance and pleasurable sensations.它还能分泌内啡肽,缓解疼痛敏感性,增强耐受力和快感。
10.Effects of Dynorphin A_(1-17) on the Activities, Immunoreactivities and mRNA Expression of cNOS and iNOS in Rat Spinal Cord and Their Correlations with NMDA Receptor, Calcium and c-fos;强啡肽对脊髓cNOS与iNOS活性、分布和基因表达的影响及机制
11.Effects of Dynorphin and the Involvement of Excitatory Amino Acid on Spinal Cord Injury;强啡肽致脊髓损伤的机理和兴奋性氨基酸在其中作用的研究
12.Expression and Modulation of Dynorphin A and Preprodynorphin mRNA in Rat Hypothalamus under Hypoxia;低氧诱导大鼠下丘脑强啡肽A及其mRNA的表达与调节
13.Effects of Swimming of Different Intensity and in Different Duration on β-endorphin Level in Plasma and Hypothalamus;不同强度和时间的游泳对血浆和下丘脑β-内啡肽水平的影响
14.Effect of Intraoperative Fluid Management on Dynorphin A Expression of Skin in Patients Undergoing Abdominal Surgery术中液体治疗对腹部手术患者皮肤强啡肽A表达的影响
15.The developing changes of dynorphin A(1-13) in rat cortex and the cerebral water content after cerebral ischemia脑缺血大鼠脑皮层中强啡肽A(1-13)的经时表达及脑含水量的变化
16.EFFECT OF ACUTE HYPOXIA ON THE CONTENT OF B-EP IN THE BRAIN OF RATS高原急性适应过程中大鼠脑内β-内啡肽含量的实验研究
17.Construction of Retro-vector Containing Human Proenkephalin Gene and Its Expression;人前脑啡肽原基因逆转录病毒载体的构建及其表达
18.Effect of scorpion venom heat-resistant protein on expression of proenkephalin in the rats hippocampus蝎毒耐热蛋白对大鼠海马内前脑啡肽原表达的影响
相关短句/例句

preprodynorphin前强啡肽原
1.By using intrathecal administration of antisense oligodeoxynucleotide (AS-ODN) against preprodynorphin mRNA in rats, we observed that this treatment could block both the formalin-induced behavioral nociceptive responses and the increased expression of dynorphin A (1-8) in the dorsal horn, with the increased expression of c-Fos protein being unchanged.应用大鼠鞘内预先注入对抗前强啡肽原表达的反义寡聚核苷酸技术 ,观察了此处理对动物后脚掌注射福尔马林 ( 5 %,1 0 0μl)诱发的行为痛反应的影响 ,同时在行为检查的 1 h后立即用免疫组化技术检测了大鼠腰髓背角 c-Fos蛋白和强啡肽 A( 1 -8)的表达。
3)preprodynorphin mRNA前强啡肽原mRNA
1.Objective:To investigate the effects of long-term administration of morphine on preprodynorphin mRNA (PPD mRNA) levels in different brain sites of rats, including hypothalamus, hippocampus and striatum.目的·· :观察慢性腹腔注射(ip)吗啡对大鼠下丘脑、海马、纹状体中前强啡肽原mRNA(PPDmRNA)表达的影响。
4)dynorphin强啡肽
1.Effect of N-nitro-L-arginine on the Inhibition of Morphine Physical Dependence in Rats and Its Dynorphin A Mechanism;N-硝基-L-精氨酸抑制大鼠吗啡身体依赖的强啡肽机制
2.Changes of extracellular adenosine concentration in spinal cord in dynorphin-induced paralysis rats;强啡肽A致截瘫大鼠脊髓组织细胞外腺苷浓度的变化
3.Research on mechanism of non-opioid receptor in dynorphin-induced spinal cord injury;强啡肽致脊髓损伤中非阿片样受体机制的研究
5)prodynorphin前强啡肽
1.) application antisense oligodeoxynucleotide (AS-ODN) to induce prodynorphin (Pro-Dyn) mRNA and observed the degree of inflammatory edema after the formalin injection in rats to prove whether the quantity of dynorphin A in nerve centre could effect the degree of periphery inflammation.目的:利用鞘内注射前强啡肽mRNA的反义寡聚核苷酸,观察由福尔马林引起的大鼠后脚炎性水肿程度的变化,来证明脊髓背角中强啡肽(dynorphin,Dyn)A的量可能影响外周炎症反应的大小。
2.Total RNA in hippocampus was extracted and primers of enkaphalin or prodynorphin were respectively added for RT-PCR reaction.方法:采用单纯束缚的方法建立慢性束缚性应激的大鼠模型,提取海马总RNA,采用RT-PCR反应扩增脑啡肽和前强啡肽基因,比较二者在海马中的表达情况。
3.Aim: To investigate the changes of enkaphalin mRNA and prodynorphin mRNA gene expression in rat brain regions with chro-(nic) immobilization stress and the influence of Chinese herbs.目的:研究慢性束缚应激时大鼠海马脑啡肽和前强啡肽mRNA基因表达的变化以及逍遥散、四君子汤、金匮肾气丸三种中药复方对其的影响。
6)dynorphin A强啡肽A
1.Up-expression of dynorphin A aggravates inflammatory edema induced by formalin test in rats;脊髓背角中强啡肽A表达的上调对福尔马林引起的大鼠炎性水肿的影响
2.Methods: Twenty patients of lumbar intervertebral disk prolapse were treated by extradural injection of Mailuoning, the spontaneous release of dynorphin A (Dyn A) in cerebrospinal fluid (CSF) before and after treatment were measured and compared with that of the 20 cases in the control group to determine the therapeutic effect of Mailuoning.方法 :用硬膜外注射中药脉络宁的方法治疗腰椎间盘突出症患者 (实验组 ) 2 0例 ,设对照组 2 0例 ,并观察两组患者治疗前后脑脊液中强啡肽A(Dyn A)的自发释放趋势 ,以判定其疗效。
3.Objective:To investigate the effects of progesterone on morphine rewarding effect and levels of dynorphin A (DynA) in rat brain.目的:观察孕酮对于吗啡所致奖赏效应及相关脑区中强啡肽A水平的影响。
延伸阅读

强啡肽 A (1-13)分子式:C75H126N24O15分子量:1603.97CAS号:72957-38-1性质: