N-甲基-4-苯基-1,2,3,6-四氢吡啶,N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)
4-(4-Chlorophenyl)-1,2,3,6-tetrahydropy-ridine4-(4-氯苯基)-1,2,3,6-四氢吡啶
3)4-Phenyl-1,2,3,6-tetrahydropyridine4-苯基-1,2,3,6-四氢吡啶
4)1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine1-甲基-4-苯基-1,2,3,6-四氢吡啶
1.Objective To explore the possible role of neural cell adhesion molecule(NCAM) in mediating the protective effect of glial cell line-derived neurotrophic actor(GDNF) on dopaminergic(DA) neurons in the mesencephlic cell culture injured by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP).目的研究神经细胞黏附分子(neural cell adhesion molecule,NCAM)在胶质细胞系源性神经营养因子(glial cell line-derived neurotrophic factor,GDNF)保护1-甲基-4-苯基-1,2,3,6-四氢吡啶(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPTP)损伤的多巴胺(dopamine,DA)能神经元中的作用。
2.1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced animal models are ideal models of human Parkinson s disease, in terms of neurobiochemical and histopathological changes, as well as behavioral disorders.用神经毒素1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)制备的动物模型,无论在神经生化和病理组织学特征,还是在运动行为表现方面都酷似人帕金森病(PD),是目前研究PD的理想模型。
3.Objective To investigate the neuroprotective effects of a sapogenin from Rhizoma Anemarrhenae(ZMR) on nigrostriatal dopaminergic neurons in chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-lesioned mouse model.目的研究知母活性成分ZMR对慢性1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)损伤小鼠模型黑质纹状体通路多巴胺神经元的影响。
5)MPTP1-甲基-4-苯基-1,2,3,6-四氢吡啶
1.Objective To investigate the immune response of the substantia nigra in the MPTP-induced model of Parkinson’s disease(PD), and explore the regulation of ganoderma spore oil on the inflammatory response induced by MPTP.目的研究1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)所致帕金森病模型中脑黑质区的免疫应答情况,探讨灵芝孢子油对MPTP引起的神经炎症反应的调节作用。
2.Objective: To investigate the neuroprotective effects and mechanisms of Chunxiong Chatiao pulvis(CXCT) on the MPTP-induced dopaminergic neurodegneration in mice model of PD.目的:研究川芎茶调散对1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)致小鼠多巴胺(DA)神经元损伤的保护作用,并从抗氧化角度探讨其神经保护作用的可能机制。
6)1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)
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4-苯基-1,2,3,6-四氢吡啶分子式:C11H13N分子量:159.23CAS号:10338-69-9性质:暂无制备方法:暂无用途:暂无