1)β-amyloid peptide(Aβ)Aβ肽
1.Alzheimer s disease(AD) is characterized pathologically by the deposition of amyloid,the major component of which is a 40-42 residue peptide known as the β-amyloid peptide(Aβ).铜锌等过渡金属离子与Aβ肽的沉积直接相关,研究这些金属离子与Aβ肽的作用对理解老年痴呆症的病理过程并开发相应的治疗药物至关重要。
2.Coordination modes between Cu(II) ion and β-amyloid peptide(Aβ) were studied by syntheses of model complexes to mimic the coordination environments.通过合成模型化合物模拟铜离子与Aβ肽的配位环境,利用配合物的晶体结构及可见光谱数据,研究了铜离子与Aβ肽的配位模式,发现铜离子与Aβ肽不太可能形成N2O2配位模式。
英文短句/例句
1.Molecular Modeling of the Inhibitory Mechanism of Cu(Ⅱ) on the Aggregation of Amyloid β-peptide and Its Ion Channel-like Nanotube Structure;铜（Ⅱ）抑制Aβ肽聚集机理及纳米管状类—离子通道结构的分子模拟
2.Study on the Coordination Modes between Zinc(Ⅱ) Ions and β-Amyloid Peptide with the Method of Model Compounds;以合成模型化合物方法对锌离子与Aβ肽配位模式的研究
3.A Preliminary Study on the Coordination Modes Between Cu(II) ion and β-Amyloid Peptide with the Method of Model Compounds以模型化合物方法对铜离子与Aβ肽的配位模式的初步研究
4.RNS-mediated Damage to Endothelial Cell Line and the Protective Mechanisms of Ginsenoside Rg1 on Beta-amyloid-induced RNS Damages活性氮介导的内皮细胞株损伤及人参皂苷Rg1对Aβ肽源性活性氮损伤保护机制研究
5.The Effect of Acidic Neuropeptide on Expressions of NGF, Aβ, NMDAR1 and mGluR2, 3 in Brain of AD Rat;酸性肽对AD大鼠脑中NGF、Aβ、NMDR1、mGluR2，3表达的影响
6.Screenning the Peptide Against the Aggregation of β-Amyloid Peptide via Phage Display;利用噬菌体展示技术筛选抗Aβ聚集的短肽
7.Effect of Acidic Neuropeptide on Expressions of Aβ in Brain of AD Rat酸性肽对AD大鼠学习记忆能力及Aβ表达的影响
8.Effects of Aβ(10-21) on Potassium Currents of Hippocampal Pyramidal Neurons & the Neuroprotective Function of Lithium Chloride;Aβ（10-21）肽对海马锥形细胞钾电流的影响及LiCl的神经保护功能
9.Spectral Study on the Interaction of Copper(Ⅱ)、Zinc(Ⅱ) with Aβ;金属离子铜（Ⅱ）、锌（Ⅱ）与Aβ多肽相互作用的光谱学研究
10.Modulation of Th1 and Th2 responses to immunization with different β-amyloid and adjuvant不同Aβ多肽与佐剂组合免疫小鼠对Th1/Th2平衡的调节作用
11.Study of biologic characters of Aβ42 and Aβ42 oligomerAβ 42与Aβ 42寡聚体的生物学性质比较研究
12.The Association Among Apolipoprotein E Polymorphism β Amyloid Protein and Vascular Dementia;载脂蛋白E、Aβ与血管性痴呆的关系
13.Effects of Aβ and apoE4 on Hippocampal CA1 Synaptophysin and ChAT in Rat;Aβ与ApoE4对大鼠海马突触素及ChAT的影响
14.Synthesis and properties of Ferrocene-modified Aβ inhibitor二茂铁修饰的Aβ抑制剂的合成与性质
15.EFFECT OF HOMOCYSTEINE ON POTENTIATING ΒETA-AMYLOID NEUROTOXICITY同型半胱氨酸对Aβ神经毒性促进作用
16.The Effect of DHYZ in Treating the Injury of PC12 Induced by Amyloid Beta-Protein;地黄饮子对Aβ致PC12细胞损伤影响的实验研究
17.Study on the Protective Effects of Estrogen in the Impairment of PC12 Cells Induced by Aβ;雌激素对Aβ所致PC12细胞损伤保护作用的研究
18.Proteomic Studies of β-amyloid (25-35)-treated PC12 Cells;Aβ（25-35）诱导PC12细胞损伤的蛋白质组学研究
相关短句/例句
Aβ peptideAβ多肽
1.Study on expression and purification of Aβ peptide gene related to alzheimers disease;阿尔采末病Aβ多肽基因的高效表达及纯化研究
3)Aβ(12-28) peptideAβ(12-28)肽段
1.In this work,two-dimensional NMR methods were used to assign the 1H and 15N chemical shifts of Aβ(12-28) peptide.作者在研究中发现某些化合物可以结合于Aβ(12-28)肽段。
4)amyloidβ-peptide(Aβ)淀粉样β肽(Aβ)
5)Aβ oligomerAβ寡聚体
6)Aβ-degrading enzymeAβ降解酶
1.Role of Aβ-degrading enzymes in pathogenesis and treatment of Alzheimer s disease;Aβ降解酶在阿尔茨海默病发病机制及治疗中的作用
延伸阅读
二肽氨肽酶抑制剂分子式：CAS号：性质：抑制二肽氨肽酶(EC3.4.14.1)活性的物质。二肽氨肽酶催化二肽(基)肽的水解，即作用于多肽的肽键水解后释放出二肽，故亦名二肽(基)转移酶。该酶参与血栓形成和止血的生化反应过程。该酶抑制剂如乙酰亮氨酸精氨醛等在临床上可用作抗血栓药或抗凝药。
