1)RNA interferenceRNA干扰
1.RNA interference mediated silencing of α-synuclein in MN9D cells and its effects on cell viability;RNA干扰介导的MN9D细胞中α-synuclein表达抑制及其对细胞活力的影响(英文)
2.Effect of estrogen receptorβ knocked down by RNA interference on human osteoblast-like cell;RNA干扰基因敲低雌激素受体β对人成骨样细胞生长的影响
3.Experimental study on the treatment of hepatitis B virus infection by using the RNA interference technique;利用RNA干扰技术干扰HBeAg表达的研究
英文短句/例句
1.Knocking-down Nucleostemin Gene Expression by RNA interference Technique on the A549 CellsRNA干扰A549细胞核干细胞因子基因表达
2.In recent years, the phenomenon of RNA interference (RNAi) in cells was found.近几年,细胞内RNA干扰(RNA interference,RNAi)现象被发现。
3.From Antisense RNA to RNA Interference: an revolutionary breakthrough led by opportunity and innovation;从反义RNA到RNA干扰:科学突破的机遇与创新
4.Influence of RNAi on p21 Radiobiological Effects;RNA干扰对p21电离辐射生物效应的影响
5.Study of HER2 Gene Silencing by RNA Interference;RNA干扰沉默HER2基因的实验研究
6.RNAi on SelW Gene in Mus Musculus Muscle Cell;小鼠骨骼肌细胞SelW基因的RNA干扰研究
7.Influence of RNAi on Survivin Radiobiological Effects;RNA干扰对survivin电离辐射生物效应的影响
8.Study on RNA Interference Reversing the Multidrug Resistance of Leukemia Cell;RNA干扰逆转白血病细胞耐药性的研究
9.Reversal of Multidrug Resistance by RNA Interference;RNA干扰逆转肿瘤多药耐药的实验研究
10.Gene Transfer into the Mammalian Inner Ear Using a RNAi Non-viral Vector;RNA干扰载体活体内耳转染初步研究
11.Effect of RNA Interferance on WT1 Gene Expression;RNA干扰对WT1基因表达的抑制作用
12.The Experimental Study of Human Lung Cancer-associated Gene by RNA Interference;肺癌相关基因的RNA干扰实验研究
13.Artificial Breeding and the Study of RNA Interference of the Pine Wood Nematode(Bursaphelenchus Xylophilus);松材线虫的人工饲养和RNA干扰研究
14.Inhibition of Marek s Diseases Virus Replication by RNA Interference;RNA干扰抑制马立克氏病毒繁殖的研究
15.Research on Apple Polyphenol Oxidase Double-stranded RNA (dsRNAi);苹果多酚氧化酶双链RNA干扰(dsRNAi)研究
16.Studies of RNA Interference on SARS-associated Coronavirus Spike Glycoprotein;SARS冠状病毒刺突糖蛋白的RNA干扰研究
17.The Study of Using RNAi to Inhibit the Expression of HBeAg in Vitro;RNA干扰体外抑制HBeAg表达的实验研究
18.Inhibition of Hepatitis B Virus Expression and Replication by RNA Interference Technique;RNA干扰技术抗乙肝病毒的实验研究
相关短句/例句
RNAiRNA干扰
1.The new therapy strategy of glioma——STAT3 RNAi combined with traditional radiotherapy;脑胶质瘤治疗新策略——STAT3 RNA干扰结合传统放疗
2.Constructing and Applying the RNAi Plasmid pcDU6;RNA干扰质粒pcDU6的构建及其应用
3.EFFECTS OF RNAi-MEDIATED GENE SILENCING OF E-CADHERIN EXPRESSION ON THE BIOLOGIC BEHAVIORS OF HO-8910 CELLS;RNA干扰技术抑制上皮性钙黏附分子表达对HO-8910细胞的影响
3)RNA interferingRNA干扰
1.Cloning and sequence analyzing of the recombinant plasmid affecting gene FAK translation by RNA interfering;FAK短发夹RNA干扰重组体的构建与鉴定
2.Cloning and sequence analyzing of the recombinant plasmid affecting gene MBD2 translation by RNA interfering;MBD2靶向RNA干扰重组体的构建及序列分析
3.Cloning and sequence analyzing of the recombinant plasmid affecting gene DNMT1 translation by RNA interfering;DNMT1靶向RNA干扰重组体的构建及序列分析
4)RNA interference(RNAi)RNA干扰
1.The discovery of RNA interference(RNAi) has brought a new chance for gene therapy.RNA干扰(RNA i)现象的发现与研究,为基因治疗带来新的契机,虽然小干扰RNA(siRNA)较单链反义寡核苷酸显示了更好的稳定性与基因沉默效果,但却同样面临基因治疗药物存在的共同问题,如体内的靶向性与有效性、完善的定量分析方法等等。
2.Objective Recently, a naturally occurring gene silencing mechanism triggered by double-stranded RNA(dsRNA), RNA interference(RNAi), has been described in a number of species including Drosophila.目的 近年来 ,双链RNA介导的基因沉默 (RNA干扰 )已在许多动植物中发现 ,并成为研究基因功能的强有力的工具。
3.RNA interference(RNAi) is a phenomenon of specific silencing of genes in diverse organisms including Drodophia,Caenorhabditis elegans,epiphyte,mammalian etc.RNA干扰(RNA interference,RNAi)是生物体内1种抑制特定基因表达的机制,在果蝇、线虫、真菌和哺乳动物等很多类生物中存在。
5)RNA interference (RNAi)RNA干扰
1.Objective: To explore a new method for cancer treatment by RNA interference (RNAi).目的:本研究利用RNA干扰PPO基因,探索癌症的治疗的新途径。
2.RNA interference (RNAi) is a phenomenon in which the introduction of double-stranded RNA (dsRNA) into certain organisms and cell types causes degradation of the homologous mRNA and it is a mechanism of post-transcriptional gene silencing.RNA干扰(RNA interference,RNAi)是把双链RNA(double-stranded RNA,dsRNA)导入某些生物和细胞而引起同源mRNA降解的现象,是一种转录后基因沉默机制。
3.RNA interference (RNAi) is the process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) directs sequence specific degradation of homologous mRNA.RNA干扰 (RNAi)是一种新发现的通过 ds RNA介导的特异同源靶基因沉默途径。
6)Small interfering RNA小干扰RNA
1.Construction of magnetic small interfering RNA nanoparticles and effects of its transfection on silencing survivin gene expression and inducing human bladder cancer cell apoptosis;磁性小干扰RNA纳米微粒的制备及其转染人膀胱癌细胞对沉默survivin基因表达影响的研究(英文)
2.Suppression of vascular endothelial growth factor expression by vector-based small interfering RNA in human tongue squamous carcinoma cell line Tca8113;载体携带小干扰RNA抑制Tca8113细胞血管内皮生长因子的表达
3.Targeting the 5 -Non-translated Region of Hepatitis C Virus by Intracellularly Expressed Small Interfering RNA;细胞内表达的小干扰RNA靶向丙肝病毒5’保守区的研究
延伸阅读
感染性RNA病原RNA分子式:CAS号:性质:又称感染性RNA病原RNA;壳病毒,是一种和病毒(virus)相似的感染性颗粒。为无蛋白外壳的单链RNA,分子量1.1×105~1.3×105。它是比已知病毒都小的能在宿主细胞内自主复制的病原体之一。已知的近20种类病毒中,大部分已测得了一级结构,都是无蛋白外壳的共价闭合的单链环状RNA分子。在天然状态下类病毒RNA以高度碱基配对的棒状结构形式存在。最先是由T. O. Diener等人(1969)在马铃薯纤块茎病(potato spindle tuber disease)的病株上首先发现的,在电镜下可见到这RNA分子呈50nm长的杆状分子,共有359个碱基对,并证实是游离的RNA,为此正式命名为类病毒。它通常在宿主细胞核内,借助汁液传染,分子量75000~130000,比最小病毒还小80倍。后又相继在菊花矮缩病(chrysanthemum stunt)、菊花绿斑病(chrysanthenum chlorotic mottle)、柑橘剥皮病(citrus excortis)等患病植株中分离到低分子量的病原RNA。推测它也可能存在于其他植物、动物甚至人体内。绝大部分类病毒均具有共同的结构特征:(1)位于棒状结构中心有一个高度保守的序列;(2)靠近这一保守中心区的左侧有一个多聚嘌呤区;(3)棒状结构左侧序列保守性强,右侧变异性大。它可能是通过核苷酸序列或结构改变直接与寄主细胞相互作用、干扰细胞的代谢而致病。对类病毒的研究可能为揭示生命起源和进化、生命过程的实现等生命科学的重大理论问题作出贡献。
