Smad,Smads
1)SmadsSmad
1.Role and Mechanisms of TGF-β_1/Smads Signal Transduction Pathway in Early Inflammatory Response after Severe Thermal Injury;TGF-β_1/Smads信号转导通路在严重烧伤早期炎症反应中的作用和机制
2.Effects of TGF-β1 on Expressions of TGFβ Receptors and TGFβ-related Smads and Cell Proliferation of Human Cutaneous Squamous Carcinoma A431 Cells;TGF-β1对人皮肤鳞癌A431细胞TGF-β受体及相关Smads表达和细胞增殖的影响
英文短句/例句

1.Smad Signaling Mechanism in atRA-induced Cleft Palate;维甲酸诱导腭裂发生的Smad信号机制
2.Investigation of Smad Expression in Ulcerative Colitis;Smad分子在溃疡性结肠炎中的表达研究
3.TGF-β/Smad in Prostate Cancer:An Update前列腺癌中TGF-β/Smad信号的研究进展
4.Signal transduction of BMP/Smad and its relationship with mammalian folliculogenesisBMP/Smad信号通路与哺乳动物卵泡发生
5.Cloning and expression of Smad proteins in 293T cellsSmad家族蛋白在真核细胞中的表达
6.Effect of Shenkangwan on the TGF-β_1/Smad Signaling Pathway in Diabetic Nephropathy;肾康丸对糖尿病肾病TGF-β_1/Smad信号通路的影响
7.Effects of Salidroside on TGFβ-Smad Signaling Pathway in Rats of Experimental Hepatic Fibrosis;红景天甙对肝纤维化大鼠TGFβ-Smad信号通路的影响
8.Preliminary Study of TGF-β_1/Smad Transduction Pathway in Keloid;瘢痕疙瘩中TGF-β_1/Smad传导通路的初步研究
9.The BMP-Smad Signal Passageway during Orthodontic Tooth Movement in Rats;大鼠正畸牙齿移动过程中BMP-Smad的信号通路研究
10.Smad7 Antagonizes TGF-β Signaling by Interfering with Functional Smad-DNA Complex Formation in the Nucleus;Smad7通过干扰Smad-DNA复合物的形成抑制TGF-β信号
11.Effect of Simvastatin on Smads Protein Expression in the Infarcted Rat Heart辛伐他汀对心肌梗死后大鼠心肌Smad表达的影响
12.Role of forkhead L2 in transforming growth factorbeta/Smad signaling pathwaymediated activation of hepatic stellate cellsFoxL在TGF-β/Smad通路中对肝星状细胞活化的影响
13.Expression and Significance of TGFβ1 and Smad 4 Gene in Human Hepatocellular Carcinoma TissuesTGFβ1与Smad 4基因在肝细胞癌中的表达及意义
14.The Effection of TGFβ/Smad Cell Sigal Passway to the Expression of VEGF/CTGF in Human Retinal Endothelial Cells;TGFβ/Smad信号通路对人视网膜血管内皮细胞VEGF/CTGF的影响
15.Experimental Study on Suppression of Smad in Keloids by Small Interfering RNAs;应用小干扰RNA抑制人瘢痕疙瘩Smad基因表达的实验研究
16.The Effects of TGF-β/Smad Signal on the Growth and Apoptosis of Human Rhabdomyosarcoma Cell Line RD;TGF-β/Smad信号对人横纹肌肉瘤细胞RD生长和凋亡调控的研究
17.The Expression and Effects of CTGF、TGF and SMAD Signaling Patnway During Corneal Wound Healing;角膜创伤愈合中TGF、CTGF的表达及MAPK、Smad信号传导通路的实验研究
18.The TGFβ1/Smad Signaling Pathway is Functional in Cultured Rat Mesangial Cells;大鼠肾小球系膜细胞TGF-β1/Smad信号转导通路的实验研究
相关短句/例句

TβR/SmadsTβR/Smad
3)Smad proteinSmad蛋白
1.Objective To investigate the effect of ligustrazine on the intracellular translocation of Smad protein in HSC-T6 cell line.目的探讨川芎嗪对HSC-T6细胞Smad蛋白细胞内转位的影响。
2.Objective To investigate the localization of Smad protein 2, 3, 6, 7 and their changes of expression in experimental interstitial fibrosis model in rats.抗Smad蛋白表达下降可能是该模型TGF-β1致肾纤维化作用的主要原因。
3.Smad protein is the important substrate of TGFβ1.TGFβ1(transforming growth factor beta 1,TGFβ1)是目前公认最强的致肝纤维化的细胞因子,Smad蛋白是目前发现的TGFβ家族受体激酶的关键作用底物,TGFβ1激活肝星状细胞(hepatic stellate cell,HSC)的信息转导须经过Smad蛋白家族,才能将信息传入细胞核内,启动胶原基因表达而引起肝纤维化。
4)common-partner Smad共有Smad
5)SmadSmad蛋白
1.TGF β plays a crucial role in the renal fibrosis and Smads mediate the intracellular signal transduction of TGF β.TGF- β是肾纤维化发生、发展中的必需因子 ,Smad蛋白是 TGF- β受体的胞内激酶底物 ,介导了 TGF- β的胞内信号转导。
2.Method:Detection the expression of Smad protein in fibroblasts before the expression of αsmooth muscle actin.方法:利用免疫组织化学方法检测成纤维细胞表达α平滑肌肌动蛋白之前表达Smad蛋白的改变。
3.The Smad family of proteins has recently been identified as a predominant signaling pathway by which TGF-B activates the transcription of several well-known TGF-B-inducible genes.近年来,Smad蛋白家族被认为是一些TGF-β诱导基因的主要信号通路,其中TGF-β起转导作用。
6)Smad proteinsSmad蛋白
1.Effect of carvedilol on expression of Smad proteins mediated by AngⅡ in cardiac fibroblasts;卡维地洛对血管紧张素Ⅱ介导的心脏成纤维细胞Smad蛋白表达的影响
2.Smad proteins possess special structure and property and play significant roles in TGF-β signal transduction pathway.Smad蛋白是转化生长因子-β(transforming growth factor-β,TGF-β)信号转导通路中关键的介质,TGF-β通过结合细胞表面特异性受体而启动下游的Smad蛋白传导通路。
3.Objective To explore the molecular mechanisms of the Smad proteins in lung cancer development, we constructed the Smad proteins eukaryotic expression vectors and detected their expressions in the SV40-transformed embryonic kidney 293T cell line.目的:探索Smad蛋白在肺部肿瘤形成过程中的分子机制,构建带FLAG标签的smad1、2、3、4的真核表达载体,并检测其在293T细胞中的表达。
延伸阅读

1-[β,β,β-三(对氯苯基)丙酰]-4-甲基哌嗪分子式:C26H25CL3N2O分子量:487.85CAS号:2390-22-9性质:该品溶点213-215℃。作兽用驱虫药时常用基盐,又称Dieroden。盐酸盐的熔点为267-269℃,易溶于热水和醇。制备方法:以三(对氯苯基)甲醇(Ⅰ)为原料,与氰乙酸加成得β,β,β-三(对氯苯基)丙腈(Ⅱ),经浓硫酸水解得β,β,β-三(对氯苯基)丙酸(Ⅲ),再用五氯化磷酰氯化,得到β,β,β-三(对氯苯基)丙酰氯(Ⅳ),最后与N-甲基哌嗪缩合制得海涛林。用途:该品为治疗牛、羊矛形腔吸虫病的高效药物,具有作用强、驱虫率高(96%以上)、毒性低、适口性好等优点,国外畜牧业应用十分广泛。