美金刚胺,memantine
1)memantine美金刚胺
1.Determination of Memantine hydrochloride in rats’plasma by precolumn derivation-HPLC柱前衍生化HPLC测定大鼠血浆中的盐酸美金刚胺
2.The labeling precursor of N2S2-Memantine was synthesized from memantine via reaction with chloroacetyl chloride,followed by condensation with N2S2,and then deblocking protecting group with Hg(OAc)2 and H2S.以美金刚胺为原料,先与氯乙酰氯反应,再与二硫二氮缩合,最后与醋酸汞硫化氢反应脱巯基保护基得到标记前体N-[2-(N-(2-巯基乙基))氨基甲酰甲基]-N-(2-巯基乙基)-3,5-二甲基金刚烷胺基乙酰胺。
3.Several prodrugs of antidepressant Venlafaxine, antidementia memantine and antitumor hydroxyurea were designed and synthesized in order to enhance up the specific selectivity.本课题进行了抗抑郁药物文拉法辛,老年痴呆治疗药物美金刚胺及抗脑肿瘤药物羟脲的前体药物制备与评价研究,以期获得提高脑靶向释放的新化合物。
英文短句/例句

1.Determination of Memantine hydrochloride in rats’plasma by precolumn derivation-HPLC柱前衍生化HPLC测定大鼠血浆中的盐酸美金刚胺
2.Determination of partition coefficients of memantine hydrochloride and its prodrug PMHHPLC测定盐酸美金刚胺及其前药的脂水分配系数
3.The researchers also found that memantine was able to dampen brain activity in some affected areas and reduce pain accordingly.研究人员也发现美金刚胺能够抑制脑中受侵袭部位的活动从而减少疼痛。
4.Synthesis of N-(3-chlorophenyl)-1-adamantanecarboxamideN-(3-氯苯基)金刚烷甲酰胺的合成
5.Synthesis of Tromantadine and Its Analogs;抗病毒药物曲金刚胺及其类似物的合成
6.Study on the Effects of Modified Amantadine Against Avian Influenza Virus;金刚烷胺修饰物(NAM)抗禽流感病毒实验研究
7.Mechanism of modified amantadine against influenza A(H5N1) virus金刚烷胺修饰物抗禽流感病毒的作用机制
8.Bioequivalence Study of Rimantadine Hydrochloride Granules in Chinese Healthy Volunteers盐酸金刚乙胺颗粒人体生物等效性研究
9.Assembly Chemistry of Classical Polyoxometalates Decorated by Transition Metal-Rigid/Flexible Organonitrogen Polymeric Moiety过渡金属—刚性/柔性有机胺基团修饰的经典多金属氧簇的组装化学
10.Commonly used drugs such as methyldopa, Symmetrel, Inderal, cimetidine, scopolamine seasickness patches, and digitalis preparations.常用药物,如甲基多巴、盐酸金刚烷胺、心得安、甲腈咪胺、莨菪胺晕船膏药和洋地黄制剂。
11.Why Buddha s Warrior Attendant Has a Glaring Look? --A Tentative Study of Feng Qi s Aesthetic Thoughts;金刚何为怒目?——冯契美学思想初论
12.Pharmacokinetics of memantine hydrochloride capsule in Chinese healthy volunteers盐酸美金刚胶囊人体药代动力学研究
13.Study on Chinese Herb Medicine of Anti-Avian Influenza Virus and Variation of M2 Gene Induced by Amantadine Hydrochloride;抗禽流感病毒中药及盐酸金刚烷胺诱导M2基因变异的研究
14.Determination of Tetracyclines and Metabolites of Rimantadine in Biologic Samples by Liquid Chromatography-mass Spectrometry;液质联用法分析生物样品中四环素类药物和金刚乙胺代谢物
15.The Protection of Amantadine Hydrochloride to the Retinal Ganglial Cell from Acute Ocular Hypertension in Rabbit;盐酸金刚烷胺对兔急性高眼压视网膜神经节细胞损伤的保护作用
16.Study on Carbon Film Were Prepared from Polyimide Film and Diamond-Like Carbon Film Were Deposiited on Carbon Film;聚酰亚胺基碳膜的制备及其等离子镀制类金刚石薄膜的研究
17.The Target of Amantadine Inhibiting M2 ion Channel and Screening Inhibitors of BM2M2离子通道中金刚烷胺的作用位点研究及BM2离子通道阻断剂筛选
18.Effect of modified amantadine on immune function of mice infected with influenza A(H5N1) virus金刚烷胺修饰物对禽流感病毒感染小鼠免疫功能的影响
相关短句/例句

memantine hydrochloride盐酸美金刚胺
1.Study on Analysis Method of Memantine Hydrochloride Tablets;盐酸美金刚胺含量分析方法的研究
2.Comparing to different reaction methods, the method starting from 1,3-dimethyladamantane was certified with the memantine hydrochloride synthesized by bromination ,acetimidolation, hydrolysis and acidation.通过比较不同的反应路线,确定了以1,3-二甲基金刚烷为原料,经溴代、乙酰氨基化、水解反应最后经酸化得到盐酸美金刚胺
3.A HPLC-ELSD method was established for determination of memantine hydrochloride in memantinetablets.建立了HPLC-ELSD测定美金刚胺片中盐酸美金刚胺的含量。
3)memantine hydrochloride盐酸美金刚烷胺
1.HPLC determination of memantine hydrochloride tablets;高效液相色谱法测定盐酸美金刚烷胺片的含量
4)adamantaneamine金刚烷胺
1.Syntheses and characterization of transition metal(Ⅱ) complexes of Schiff base derived from adamantaneamine and salicylaldehyde;金刚烷胺水杨醛Schiff碱过渡金属(Ⅱ)配合物的合成与表征
2.Solid-phase synthesis and spectral characterization of Schiff bases derived from adamantaneamine and benzaldehyde derivant;金刚烷胺与苯甲醛衍生物Schiff碱的固相合成及光谱表征
3.Six newsolid complexes were synthesized from tranisition metals with a Schiff base(C18H23NO2,L) derived fromadamantaneamine ando-vanillin,and characterized by elemental analysis,molarconductance,infrared spectra,thermal analysis.合成了金刚烷胺邻香兰素Sch iff碱配体(C18H23NO2,以L表示)与过渡金属的6种新的配合物[MC l2L](M=Mn(Ⅱ),Co(Ⅱ),N i(Ⅱ),Cu(Ⅱ),Zn(Ⅱ),Cd(Ⅱ)),用元素分析、摩尔电导、红外光谱和热重分析表征了配合物的结构;讨论了配体与中心金属离子的键合情况并推测了配合物的结构,每一中心金属离子与Sch iff碱配体中的酚羟基氧、甲氧基氧及2个氯离子发生配位,其配位数为4。
5)rimantadine金刚乙胺
1.A Zinc complex [ZnCl2(HL)2] with Schiff base HL derived from rimantadine and salicylaldehyde was synthesized and characterized by elemental analysis, infrared spectra, 1H NMR spectra,molar conductance, ultraviolet and visible spectra, thermal analysis.金刚乙胺盐酸盐是一种具有广泛开发潜力的抗病毒和镇静药物。
6)amantadine[英][?'m?nt?di:n][美][?'m?nt?,din]金刚烷胺
1.Inhibitory effect of modified amantadine on avian influenza (H_5N_1) virus;金刚烷胺修饰物对禽流感(H_5N_1)病毒的抑制作用
2.Investigation on Drug Resistance of Influenza H3 Subtype Virus Amantadine:A Report from 2003 to 2005 in Bejing District;2003年~2005年北京地区甲3型流感病毒流行株金刚烷胺耐药性调查
3.Analysis of relationship between M2 protion mutation with resistance to Amantadine of epidemic strain of influenza A virus in human;人群甲型流感病毒M2蛋白变异与金刚烷胺耐药性分析
延伸阅读

美金刚胺分子式:CAS号:性质:又名美金刚胺,盐酸美金刚胺。油状物。折射率1.4941。盐酸盐熔点258℃。抗震颤麻痹药。本品通过释放多巴胺,直接或间接地兴奋多巴胺受体而起作用。用于治疗震颤麻痹综合征。制剂有片剂、针剂、滴剂。