1)pharmacophore['fɑ:m?k?f?:]药效基团
1.Overview of studies on the anti-tumour pharmacophore of traditional Chinese medicines;中药抗肿瘤有效成分的药效基团研究概况
2.Present paper elucidates the following aspects; evolution of chemical classes of insecticides that act on insect nAChRs, structure and function of nAChRs, structure - activity of nicotine analogs, the structure modified and selectivity of neonicotinoid insecticides, and the pharmacophore of neonicotinoids.本文就以下几方面作了详细的阐述:作用于昆虫nAChRs的各类化学杀虫剂的演绎,nAChRs的结构与活性,烟碱类似物的结构与活性,新烟碱类杀虫剂的结构修饰及其选择性,以及新烟碱类的药效基团。
3.Functional fragments contain structural elements known as pharmacophores which generate the bioactivity of the drugs,while structural fragments assemble the functional fragments into a specific skeleton also crucial for the activity.功能性分子片段包含药物产生生物活性所必须的结构单元(简称药效基团);而结构性分子片段则是将功能性分子片段连接起来从而形成特定结构的分子骨架。
2)Pharmacophore['fɑ:m?k?f?:]药效基团模型
3)pharmacophore['fɑ:m?k?f?:]药效团
1.3D-QSAR and Pharmacophore Modeling of Growth Hormone Secretagogues;促生长激素释放素三维定量构效关系及药效团模型
2.Strategy of molecular drug design:pharmacophore and scaffold hopping;药物分子设计的策略:论药效团和骨架迁越
3.Study of concerted mechanism between P-glycoprotein and cytochrome P4503A4 by 3D-pharmacophore modeling;基于3D-药效团的P糖蛋白和细胞色素P4503A4的协同作用机理研究
英文短句/例句
1.Constructing the Pharmacophore Models of Tyrosinase Inhibitors by DISCO Method距离比较法构建酪氨酸酶抑制剂的药效团模型
2.The Study of Pharmacophore Modeling and Molecular Docking for Adenosine Receptor Antagonists;腺苷受体拮抗剂药效团模建和分子对接研究
3.Pharmacophore model of integrin α_vβ_3 antagonists整合素α_vβ_3受体拮抗剂药效团模型的研究
4.Study on the Methodology of Chinese Medicine Virtual Screening Based on Pharmacophores基于三维药效团的活血化瘀中药虚拟筛选方法学研究
5.The Molecular Dock of Combination Pharmacophore's Assessment Method and Their Potential Use in the Development of New Drugs整合药效团评价方法的分子对接技术及其在新药研究中的应用
6.Design, Synthesis, Activity Evaluation of Thienopyridine Derivatives and Its Pharmacophore Model噻吩并吡啶类衍生物的设计、合成、活性评价及其药效团模型
7.Pharmacophore Model Generation and Docking Studies of Cholesteryl Ester Transfer Protein (CETP) Inhibitors胆固醇酯转运蛋白抑制剂的药效团模型构建和分子对接研究
8.Application of the Support Vector Machine in Constructing Interlenlein-1βooverting Enzyme Inhibitors Pharmacophore Model支持向量机在构建白介素-1β转化酶抑制剂药效团模型中的应用
9.Insights into the discovery of new 5-HT1A receptor ligands:receptor based pharmacophore5-羟色胺1A受体配体发现新思路:基于受体的药效团(英文)
10.Human Immunodeficiency Virus Integrase Pharmacophore Model Derived from Diketoacids Inhibitors人类免疫缺陷病毒整合酶二酮酸类抑制剂的三维药效团构建
11.Comparative pharmacophore analysis of dual dopamine D_2/5-HT_(2A) receptor antagonists双重作用的多巴胺D_2/5-HT_(2A)受体拮抗剂比较药效团分析
12.Pharmacophore modeling of dual angiotensin Ⅱ and endothelin A receptor antagonists血管紧张素受体和内皮素受体双重受体拮抗剂药效团模型的研究(英文)
13.Performance Check Research for Shiyitang Pharmaceutical Factory of Harbin Pharmaceutical Group;哈药集团世一堂制药厂绩效考核研究
14.Experience for Training and Improving Professional Quality of Pharmacists by Drug Stocktaking做好药品清点工作 打造高效工作团队
15.Enhanced Production of Mycelia in Submerged Cultivation of Cordyceps Ophioglossoides, and Active Component Analyse of Mycelia;大团囊虫草菌的发酵工艺优化及药效成分分析
16.Shiyitang Making Medicine Factory GMP Reformation Projection Economic Benefit Value Research of Harbin Medicine Group;哈药集团世一堂制药厂GMP改造项目经济效益评价研究
17.Redesign Project of AD Company Saledepartment Evaluation System;吉林敖东药业集团销售人员绩效考评优化方案设计
18.Analyzes of Team Cooperation Team Competition and Team Efficiency对团队合作团队竞争团队效率的探讨
相关短句/例句
Pharmacophore['fɑ:m?k?f?:]药效基团模型
3)pharmacophore['fɑ:m?k?f?:]药效团
1.3D-QSAR and Pharmacophore Modeling of Growth Hormone Secretagogues;促生长激素释放素三维定量构效关系及药效团模型
2.Strategy of molecular drug design:pharmacophore and scaffold hopping;药物分子设计的策略:论药效团和骨架迁越
3.Study of concerted mechanism between P-glycoprotein and cytochrome P4503A4 by 3D-pharmacophore modeling;基于3D-药效团的P糖蛋白和细胞色素P4503A4的协同作用机理研究
4)Pharmacophore model药效团模型
1.3D - database searching based on pharmacophore model of protox inhibitors;利用原卟啉原氧化酶抑制剂药效团模型进行数据库搜索
2.3D-database searching based on ALS inhibitors' pharmacophore model;基于ALS抑制剂药效团模型的数据库搜索
3.Construction of pharmacophore model of PARP-1 inhibitor;聚腺苷二磷酸核糖聚合酶-1抑制剂药效团模型的建立
5)pharmacophore['fɑ:m?k?f?:]三维药效团
1.Pharmacophore Model Generation of HMG-CoA Reductase Inhibitors;HMG-CoA还原酶抑制剂三维药效团的构建
2.In the process of the rational screening on neuramidinase(NA)inhibitors of influenza virus,there were 4 stages:1)Prepared for drug-like compound database;2)Established 3D pharmacophore model of NA inhibitors and searched con-formations in the target compound database;3)Selected the compounds by the result of molecular docking and did post-docking analysis.介绍了理性筛选流感病毒神经氨酸酶抑制剂的全过程,共分4个阶段:1)化合物数据库类药性处理;2)建立神经氨酸酶抑制剂三维药效团并对目标数据库进行构象搜索;3)分子对接及对接后分析;4)神经氨酸酶抑制模型的建立及待测化合物的活性检测。
6)pharmocophore determination药效团确定
延伸阅读
附着剂可提高蜡质蔬菜药效
