拓扑异构酶,topoisomerase
1)topoisomerase拓扑异构酶
1.Identification of common species of dermatophytes by PCR-RFLP techniques targeting topoisomerase II gene;拓扑异构酶II基因区PCR-RFLP法鉴别常见皮肤癣菌
2.Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain昆嵛山拓扑异构酶抑制剂原料植物资源调查
3.Objective To study the roles of DNA topoisomerases(Topo) in ovarian cancer TPT-resistant cells.目的探讨DNA拓扑异构酶(Topoisomerase,Topo)在卵巢癌拓扑替康(TPT)耐药细胞A2780/TPT中的作用。
英文短句/例句

1.Development of DNA Topoisomerase Ⅱ inhibitorsDNA拓扑异构酶Ⅱ抑制剂研究进展
2.TopoisomeraseⅢWas Involved in the Eradication of Hypernegatively Supercoiled pBR322 in E.coli topA Mutants在拓扑异构酶Ⅰ缺失的大肠杆菌中拓扑异构酶Ⅲ参与高负超螺旋的消除(英文)
3.Antitumor activity of compound Mirabijalone B and its effect on DNA topoisomerasesMirabijalone-B的抗肿瘤效应及对DNA拓扑异构酶的影响
4.Expression of topoisomerase Ⅱα in breast cancer neoadjuvant chemotherapy patients乳腺癌新辅助化疗对拓扑异构酶Ⅱα表达的影响
5.Investigation on the Raw Materials Plants Resources of Topoisomerase Inhibitor in Kunyu Mountain昆嵛山拓扑异构酶抑制剂原料植物资源调查
6.The category, characteristic of DNA topoisomerases and research progress of inhibitorDNA拓扑异构酶Ⅰ和Ⅱ的结构特性及抑制剂的研究进展
7.The Experimental Research and Clinical Observation on the Treatment of Refractory/relapse Acute Myeloid Leukemia with Topoisomerase Ⅰ Inhibitors Topotecan;拓扑异构酶Ⅰ抑制剂拓扑替康治疗难治/复发性急性髓系白血病的基础与临床研究
8.The effect of EB virus bhrfl gene expressing on the topoisomerase Ⅰ expression in nasopharyngeal carci noma cell lineEpstein-Barr病毒bhrfl表达对鼻咽癌细胞株CNE2拓扑异构酶Ⅰ表达的影响
9.Objective:To investigate the correlation between Topo Ⅱα expression and chemosensitivity in epithelial ovarian carcinoma (EOC).目的 :研究卵巢癌拓扑异构酶Ⅱα表达与化疗敏感性的关系。
10.The Antitumor Compounds Targeted on DNA Topoisomerases Screening;基于DNA拓扑异构酶的抗肿瘤活性物质的靶向筛选
11.Expression of Topo Ⅱα and Ki-67 in Human Hepatocellular Carcinoma and Its Significance;拓扑异构酶Ⅱα与Ki-67在肝细胞癌中的表达及意义
12.The Antitumor Activity of Albaconol and Its Effect on DNA Topoisomerase Activity and Angiogenesis Activity in Vitro;Albaconol的抗肿瘤活性及对拓扑异构酶活性和血管生成的影响
13.Study on the Mechanism for Topoisomerase Ⅱ Poison Teniposide Against Oral Cancer Cells;拓扑异构酶抑制剂替尼泊甙抗口腔癌机制的研究
14.Prognostic significance of topoisomerase II alpha in patients with glioma;DNA拓扑异构酶Ⅱalpha在脑胶质瘤中的表达及与预后的相关性研究
15.Study of the Relationship between Topoismerase and the Prognostic, MDR of Ovarian Cancer;拓扑异构酶与卵巢癌预后及多药耐药关系的研究
16.Emodin inhibited ATP binding to Topoisomerase II to induce DNA double-strand breaks大黄素通过抑制ATP与拓扑异构酶II的结合导致DNA产生双链断裂
17.Screening of inhibitors of recombinant human DNA topoisomerase Ⅰ from mangrove endophytic fungi从红树林内生真菌筛选重组人DNA拓扑异构酶Ⅰ抑制剂的研究
18.Expression of topoisomerase Ⅰ in human pathological scar tissues拓扑异构酶Ⅰ在人病理性瘢痕组织中的表达分析
相关短句/例句

topoisomerase Ⅱ拓扑异构酶
1.Objective To detect the expression of p53、multidrug resistance gene1(mdr1) gene,glutathione S-transferase(GST-π),lung resistance protein(LRP),topoisomerase Ⅱ(Topo Ⅱ),and to evaluate their relationship with staging and classification of cancer,differentiation degree,lymphatic metastasis,and tumor invasion.目的检测食管癌组织中P53、多药耐药基因(mu ltidrug resistance gene1,MDR1)及其编码产物P-糖蛋白(p-glycoprote in,P-gp)、肺耐药蛋白(lung resistance prote in,LRP)、谷胱甘肽S-转移酶(glutath ione S-transferase,GST-π)、拓扑异构酶(topoisom eraseⅡ,TopoⅡ)的表达水平,探讨其与临床分期、分化程度、淋巴结转移、肿瘤浸润深度及病理分型的关系。
3)topoiso-merase I拓扑异构化酶
4)DNA topoisomerase拓扑异构酶Ⅰ
1.Camptothecin (CPT) compounds specifically acting on DNA topoisomerase Ⅰ (TopoI) are promising antitumor drugs, and have been widely used in the clinic.喜树碱类抗肿瘤药物是DNA拓扑异构酶Ⅰ(1bpoisomerase I,TopoI)的特异性抑制剂,目前已广泛应用于临床。
2.Camptothecin(CPT)compounds are specific inhibitors of DNA topoisomerase Ⅰ(TopoⅠ)which have been widely used in the clinic.喜树碱类抗肿瘤药物是临床广泛使用的DNA拓扑异构酶Ⅰ (topoisomeraseⅠ ,TopoⅠ )的特异性抑制剂。
3.Camptothecin(CPT)compounds are specific inhibitors o f DNA topoisomerase Ⅰ(TopoI)and have been widely used in the clinic.喜树碱类抗肿瘤药物是临床广泛使用的经典的作用于DNA拓扑异构酶Ⅰ的特异性抑制剂。
5)topoisomerase Ⅱ(TOPⅡ)TOPⅡ(拓扑异构酶)
6)DNA topoisomerasesDNA拓扑异构酶类
延伸阅读

DNA拓扑异构酶抑制剂分子式:CAS号:性质:一类能够抑制DNA拓扑异构酶活性的化合物。DNA拓扑异构酶参与催化各种遗传过程中DNA链的断开和再连接。DNA拓扑异构酶抑制剂有助于研究异构酶的作用方式和功能,已发现许多这种抑制剂可作为抗肿瘤药,如鬼臼素(epipodophyllotoxins)等一些拓扑酶Ⅱ的特异性抑制剂。