1)Cyclophilins亲环素
1.Cyclophilins (CyPs) are broad-spectrum intracellular proteins best known for their affinity for the immunosuppressive drug cyclosporin A (CsA).亲环素Cyclophilins(CyPs)是十分广谱的与免疫抑制剂药物环孢菌素A(CsA)结合的细胞内蛋白质家族 ,它们存在于从细菌到哺乳动物的几乎所有生命体中 ,并存在于细胞液和各个细胞器中。
英文短句/例句
1.Significance and Expression of CD147, Cyclophilin A and Cyclophilin B in Lesions of Patients with Psoriasis;银屑病患者皮损中CD147、亲环素A和亲环素B的表达及意义
2.Expression of CD147, Cyclophilin A and Cyclophilin B in Cutaneous Tumour;CD147、亲环素A和亲环素B在皮肤肿瘤中的表达及意义
3.The Protective Effects of Cyclophilin A on Injury of PC12 Cells Induced by Aβ_(25-35);亲环素A对Aβ_（25-35）诱导PC12细胞损伤的保护作用
4.The Expression of Cyclophilin A Protein in Human Glioma and Its Clinical Significance人脑胶质瘤中亲环素A蛋白的表达及临床意义
5.Inhibition of Proliferation and Cyclophilin A Expression in Nasopharyngeal Carcinoma Cells by Simvastatin辛伐他汀抑制鼻咽癌细胞增殖和亲环素A表达
6.A preliminary study on the mechanism associated with SLE activity and cyclophilin A in peripheral blood血清亲环素A水平与SLE活动相关机制的初步探讨
7.Study of Relativity between Expressions of Cyclophilin A in Human Gliomas and Prognosis of Patients with Gliomas亲环素A蛋白水平与脑胶质瘤预后相关性研究
8.Molecular Cloning, Characterization and Expression of Lectins from Argopecten Irradians and Cyclophilin A from Chlamys Farreri海湾扇贝凝集素基因和栉孔扇贝亲环素A基因的克隆与表达
9.Study of the Interaction of Hepatitis C Virus NS4A Protein and Calcium Modulating Cyclophilin Ligand;丙型肝炎病毒NS4A与钙离子信号调节亲环素配体相互作用的研究
10.Molecular Cloning and Expression Analysis of ACS, ACO and Cyclophilin Genes of Tea Plant (Camellia Sinensis);茶树ACS、ACO基因克隆与亲环素基因的鉴定及其表达分析
11.The Roles of CD147 on Proliferation, Activation and Chemotaxis of Jurkat Cell Induced by Cyclophilin A;CD147在亲环素A诱导Jurkat细胞增殖、活化和趋化过程中的作用
12.Expression of Cyclophilin A and CD147 in the Human Skin of Different Ages亲环素A和CD147在不同年龄正常皮肤中的表达水平研究
13.Role of Cyclophilin A on Foam Cells Directed from Vascular Smooth Muscle Cells Induced by ox-LDL亲环素A在ox-LDL诱导的血管平滑肌细胞泡沫化过程中的作用
14.Cloning and analysis of cyclophilin A gene and its promoter sequence in black tiger shrimp Penaeus monodon斑节对虾亲环素A(cyclophilinA)基因的克隆及启动子序列分析
15.Relationship between expression of Cyclophilin A and classifications in gliomas亲环素A蛋白表达水平与人脑胶质瘤分级相关性研究
16.Cloning and Bioinformatics Analysis of GCyP,a Member of Cyclophilin Family Genes in Gerbera hybrida非洲菊亲环素家族基因GCyP的克隆与生物信息学分析
17.The variation and its significance of the Cyclophilin A expression in the C6 rat glioma cells by hypoxia缺氧诱导C6大鼠脑胶质瘤细胞亲环素A蛋白表达及其意义
18.Observation on the Relationship between Expression of Cyclophilin mRNA and Effectiveness of Cyclosporin a in Aplastic Anemia Patient;再生障碍性贫血患者环孢亲和素mRNA表达与环孢素A疗效关系观察
相关短句/例句
cyclophilin亲环素
1.ObjectiveTo examine the expression of CD147, cyclophilin A and cyclophilin B in psoriatic lesions, and investigate their roles in the pathology of psoriasis and its clinical significance.目的研究CD147、亲环素A和亲环素B在正常人皮肤和银屑病皮损中的表达情况，探讨其在银屑病发病机制中的作用及临床意义。
3)cyclophilin A亲环素A
1.Research progress of cyclophilin A inhibitors;亲环素A抑制剂研究进展
2.Fusion expression,purification and activity characterization of cyclophilin A from dasyatis akajei;赤魟亲环素A的融合表达、纯化及活性特征
3.Clinical Significance of Serum Anticyclophilin A Auto-Antibodies in Patients with Sys-tem Lupus Erythematosus;系统性红斑狼疮患者血清抗亲环素A抗体检测的临床意义
4)Cyclophilin B亲环素B
1.Cloning,Expression of the Human Cyclophilin B Gene in Escherichia coli and Purification and Characterization of Recombinant Protein;人亲环素B基因的克隆表达及重组蛋白的生物活性
2.Expression of CD147, Cyclophilin A and Cyclophilin B in Cutaneous Tumour;CD147、亲环素A和亲环素B在皮肤肿瘤中的表达及意义
5)CyPA环亲和素A
1.Expression of Recombinant CyPA and its Function on Promoting Invasion of Hepatocellular Carcinoma Cells in vitro;环亲和素A的重组表达及其促进肝癌细胞侵袭转移的体外研究
6)CypD(cyclophilin D)亲环素D
延伸阅读
山地明 ,环孢素,新山地明,环孢素A药物名称：环孢素英文名：Ciclosporin别名： 环孢多肽A;环孢灵;环孢霉素A;赛斯平;山地明 ,环孢素,新山地明,环孢素A外文名：Ciclosporin A ,CsA, Cs-A, CY-A, Sandimmune, Ciclosporin, Cyspin.适应症： 主要用于肝、肾以及心脏移植的抗排异反应，可与肾上腺皮质激素同用，也可用于一些免疫性疾病的治疗。 用量用法： 口服：剂量依病人情况而定，一般器官移植前的首次量为每日每千克体重１４～１７．５ｍｇ，于术前４～１２小时１次口服，按此剂量维持到术后１～２周，然后根据肌酐和山地明血药浓度，每周减少５％，直到维持量为每日每千克体重５～１０ｍｇ止。同时给激素辅助治疗。口服液在服用前一定要用所附的吸管，以牛奶、巧克力或桔子汁等稀释，温度最好为２５℃。打开保护盖后，用吸管从容器内吸出所需山地明量（一定要准确），然后放入盛有牛奶、巧克力或桔子汁的玻璃杯中（不可用塑胶杯），药液稀释搅拌后，立即饮用，并再用牛奶等清洗玻璃杯后饮用，确保剂量准确。用过的吸管放回原处前，一定要用清洁干毛巾擦干，不可用水或其他溶液清洗，以免造成山地明药液混浊。 静注法仅用于不能口服的病人，首次静脉注射量应在移植前４～１２小时，每日每千克体重５～６ｍｇ（相当于口服量的１／３），按此剂量可持续到手术后，直到可以口服山地明为止。使用前应以５％葡萄糖或等渗盐水稀释成１:２０至１:１００浓度，缓慢地于２～６小时内滴完。 注意事项： 1.肾毒性：肾小球血栓、肾小管受阻、蛋白尿、管型尿。 2.肝毒性：低蛋白血症、高胆红素血症、血清转氨酶升高。 3.神经系统：运动性脊髓综合征，小脑样综合征及精神紊乱、震颤、感觉异常等。 4.胃肠道：厌食、恶心、呕吐。 5.用于骨髓移植虽无禁忌证，但有不良反应。 6.有高血压、多毛症。静脉给药偶可见胸、脸部发红、 呼吸困难、喘息及心悸等过敏反应。一旦发生应立即停药，严重者静注肾上腺素和给氧抢救。 7.１岁以下儿童不宜用。 储存、有效期 规格：口服液：每毫升１００ｍｇ×５０ｍｌ 丸剂：２５ｍｇ、１００ｍｇ。 静滴剂：每毫升５０ｍｇ，５ｍｌ×１０ 支.类别：免疫抑制剂
