重新甲基化,de novo methylation
1)de novo methylation重新甲基化
1.ObjectiveBy methylating the CpG islands of oncogenes (c-myc and H-ras) promoterregions with S-adenosyl-L-methionin (SAM), to explore the transcription regulationof de novo methylation on oncogenes and the effects on growth of cancer cell lines(MGC803 and HT29) and normal cell line (Chang liver cell line), and to search a newtarget for clinic diagnosis and treatment of cancers.目的:利用甲基供体S-腺苷甲硫氨酸(S-adenosyl-L-mcthionin,SAM)使恶性肿瘤细胞系MGC803、HT29中癌基因c-myc和H-ras启动子区域的CpG岛重新甲基化,研究甲基化对癌基因的转录调控作用及其对肿瘤细胞系生长增殖的生物学影响,寻找抗癌治疗的新靶点,为肿瘤的临床诊断和治疗提供准确灵敏的实验基础和理论依据。
英文短句/例句

1.De Novo Methylation on c-myc and p16 Promoters in Cancer Cells肿瘤细胞中的c-myc与p16启动子重新甲基化
2.Effect of Promoter Region de Novo Methylation on c-myc and H-ras Expression and the Growth of Cancer Cells;启动子区重新甲基化对c-myc和H-ras基因表达和肿瘤细胞生长的影响
3.Recent and new techniques used in anodic oxidation of methyl of benzene rings are also extensively discussed.著重对甲基的阳极氧化过程中运用的新技术及发展趋势作了评述。
4.Effects of Cadmium on Arabidopsis thaliana DNA Methylation重金属镉对拟南芥DNA甲基化的影响
5.DIMETHYL SULFOXIDE-A NOVEL ACTIVATING AGENT IN CONDENSATION REACTION二甲基亚砜──缩合反应中新的活化剂
6.Study on the New Catalyst of Synthesis of 2-Methylpyrazine;合成2-甲基吡嗪的新型催化剂的研究
7.A Novel Synthesis Technology of Methyl-β-Cyclodextrin甲基化-β-环糊精新型合成工艺研究
8.bis[hydroxymethyl] methyl phosphine oxide双羟甲基甲基膦化氧
9.methoxymethylated polyamide甲氧基甲基化聚酰胺
10.The univalent hydrocarbon radical, CH3-, derived from methane and occurring in many important organic compounds.甲基单价碳氢基,CH3-,由甲烷中衍生出,在许多重要有机化合物中出现
11.Lewis Acid Catalyzed Three-component Reaction of Methyl Phenyldiazoacetate,Benzyl Alcohol and N-methylisatin路易斯酸催化苯基重氮乙酸甲酯,苄醇和N-甲基靛红三组分反应
12.Study on Metallic Support Structured Catalysts for Methane Catalytic Combustion/Methane Reforming Coupling;甲烷催化燃烧耦合甲烷重整金属基催化元件的研究
13.Rose Bengal Sensitized Singlet Oxygenation of 1 - Methyl - 2 - phenylindole1-甲基-2-苯基吲哚的琥红敏化单重态氧反应
14.Study on Post Diazotization of Polymethyl Acrylic Ethyl Carbazole Ester聚甲基丙烯酸乙基咔唑酯后重氮化的研究
15.Study on the New Reaction of Different Enamines with Methyl Phenyldiazoacetate不同烯胺与芳基重氮乙酸甲酯的新反应研究
16.Novel Catalyst for Methane Steam Reforming Under Low Ratio of Steam to Methane低水碳比下新型甲烷蒸汽重整催化剂的研究
17.Recombination and Purification of DDAH2 Protein and Its Function Study;二甲基精氨酸二甲胺水解酶2重组蛋白纯化及功能研究
18.Copper(Ⅱ) Trifluoromethanesulfonate Catalyzed Insertion Reaction of Methyl Styryldiazoacetate and Arylamines三氟甲磺酸铜(Ⅱ)催化的苯乙烯基重氮乙酸甲酯和芳胺的插入反应
相关短句/例句

Diazomethylation重氮甲烷甲基化
3)the Re-Christianization重新基督教化
4)reparameterized local base surface重新参数化局部基曲面
1.When G n blending surfaces between parametric base surfaces are generated based on reparameterization of partial surface patches in the base surfaces, the shape of the reparameterized local base surfaces influence the blending surfaces greatly.讨论了基于重新参数化局部基曲面线性组合构造Gn 连续过渡曲面时重新参数化局部基曲面的形状对于过渡曲面的边界和形状的影响 ;提出了采用能量最小法使过渡曲面的边界弯曲最小来确定重新参数化局部基曲面参数域的方法 ,并提出相应的重新参数化局部基曲面的确定方法 ,从而构造较好的过渡曲
2.The blending surface between wing and fuselage is generated by a linear combination of a reparameterized local base surface on the wing and an auxiliary based s.提出了预先构造中间辅助面和辅助基曲面的方法,通过辅助基曲面和弹翼面上重新参数化局部基曲面间线性组合来构造翼身融合面。
3.The influences of base surfaces,reparameterized local base surfaces,the balance factor and the thumb weight on the blending surface are analyzed when a Gn blending surface is generated by linear combination.详细分析了采用线性组合方法构造Gn连续过渡曲面时,基曲面以及重新参数化局部基曲面、调配因子和平衡因子等对过渡曲面的影响。
5)reactivation[ri,?kti'vei??n]重新活化
1.Relationship between the formation and evolution of the South China Sea and reactivation of the Neo-Tethys;南海的形成演化与新特提斯在南海的重新活化
6)methyl rearrangement甲基重排
1.Moreover,the fragment ion (m/z 177)took a new methyl rearrangement.此外,碎片离子(m/z207)的McLafferty重排产物(m/z177)又进行了新的甲基重排反应。
延伸阅读

重新社会化重新社会化resocialization 孟新社会化(resoeialization)亦称“再社会化”。指个体以一种生活方式向另一种生活方式的转变、适应过程。重新社会化有两种类型:(l)主动重新社会化。在一定的社会环境的作用下,主体主动、自觉地改变自己的思想观念、行为规范、生活方式等以适应新的社会生活的过程。(2)强制重新社会化。少数人因个性社会化发生严重偏离,沦为违法犯罪分子,成为不合格的社会成员。国家机关就要采取强制的手段和方法,对其进行强制性的教育改造,以达到重新社会化的目的。我国的劳动改造机关、劳动教养机关、少年教养机关,就是执行对违法犯罪分子等不合格的社会成员进行强制重新社会化的任务。 (解玉教撰何为民审)