1)copper/zinc superoxide dismutase铜锌-超氧化物歧化酶
1.Objective:This study aims to investigate the effect of the deregulated expression of several antioxidant defense enzymes,including peroxiredoxin(Prx) 1,2, 5,6 and copper/zinc superoxide dismutase(Cu/Zn-SOD),on the antioxidant defense ability and basal levels of reactive oxygen species (ROS),lipid peroxidation and oxidative DNA damage in PTEN-deleted mouse embryonic fibroblasts(PTEN~(-/-) MEFs).目的:本文旨在研究抑癌基因PTEN缺失的小鼠胚胎成纤维细胞(MEFs)中抗氧化防御蛋白——过氧化物还原酶(Prx1,2,5,6)及铜锌-超氧化物歧化酶(Cu/Zn-SOD)表达下调对细胞抗氧化防御能力、细胞内活性氧(ROS)、脂质过氧化和DNA氧化损伤水平的影响,并探讨PTEN调控Prx1,2,5,6及Cu/Zn-SOD mRNA和蛋白表达的机制,以进一步完善PTEN的抑癌作用机理,对肿瘤的预防和治疗有一定的指导意义。
2)CuZnSOD铜锌超氧化物歧化酶
1.Study on Interaction Between Coper Ion and Hog Liver CuZnSOD by Spectroscopy;Cu~(2+)和铜锌超氧化物歧化酶作用的光谱学研究
2.Separation,Purification and Physical-chemical Properties of CuZnSOD from Pig Liver;猪肝铜锌超氧化物歧化酶的分离纯化与理化性质研究
3.The crude enzyme solution of CuZnSOD from tobacco was obtained by using ammonium sulˉphate to form different levels of precipitates;chloroform and alcohol to isolate the impurities and acetone to further clean-up.利用硫酸铵盐析分级分离、乙醇 -氯仿沉淀除杂、丙酮再沉淀分级得到含铜锌超氧化物歧化酶(CuZnSOD)的粗酶液 ,通过DEAE_52离子交换层析实现了3种CuZnSOD同工酶的拆分 ;进一步通过G_75凝胶层析对3种同工酶分离纯化得到2种电泳纯产品CuZnSODⅠ和CuZnSODⅢ ;SDS-PAGE实验发现CuZnSODⅠ由两个不等亚基组成 ,亚基相对分子质量分别为15050、20950;CuZnSODⅢ存在一种亚基 ,亚基相对分子质量为22950 ;实验检测到2种纯酶分子含有不等量的Cu和Zn,酶学特性实验也证实了2种蛋白酶都是CuZnSOD。
英文短句/例句
1.A Production Technology of Copper/zinc Superoxide Dismutase from Bovine Blood at a Large Scale;牛血铜锌超氧化物歧化酶规模化生产工艺研究
2.Studies on the Purification and Characterization of Copper/Zinc Superoxide Dismutase from Hog Blood;猪血铜锌超氧化物歧化酶的纯化及其性质研究
3.Expression of Human Cu/Zn Superoxide Dismutase in Escherichia Coli人铜锌超氧化物歧化酶的基因工程研究 Ⅱ.人铜锌超氧化物歧化酶在大肠杆菌中的表达
4.Chemical Synthesis and Cloning of a Gene for Human Cu/Zn Superoxide Dismutase人铜锌超氧化物歧化酶的基因工程研究——Ⅰ.人铜锌超氧化物歧化酶基因的合成与克隆
5.PURIFICATION OF Cu. Zn-SOD FROM EICHHORNIA CRASSIPES AND THE EFFECT OF SEVERAL COMPOUND ON SOD ACTIVITY;凤眼莲铜锌超氧化物歧化酶的纯化及几种化合物对其活性的影响
6.Purification of Pig Copper,Zinc-Superoxide Dismutase by Immobilized Metal Ion Affinity Chromatography固定化金属离子亲和色谱法纯化猪铜锌超氧化物歧化酶
7.Research on Purification of Copper/Zinc Superoxide Dismutase from Porcine Blood;猪血铜锌超氧化物歧化酶的分离纯化方法的研究
8.Cloning of Copper-Zinc Superoxide Dismutase Gene and Construction of Recombined Vector in Lactobacillus Casei;铜锌超氧化物歧化酶基因的克隆及重组干酪乳杆菌的构建
9.Study on the Interaction of Copper-Zinc Superoxide Dismutase with Cobalt(II)-Arginine by Visible Spectral Analysis;可见光谱法研究铜锌超氧化物歧化酶与精氨酸钴(Ⅱ)的相互作用
10.Cloning, Sequece Analysis and Expression of Copper/Zinc Superoxide Dismutase Gene from Antheraea Pernyi柞蚕铜锌超氧化物歧化酶基因的克隆与表达分析
11.Interaction Between the Active Site of the Metal Recombinase of Copper-zinc Superoxide Dismutase (CuZnSOD) and Histidine铜锌超氧化物歧化酶的金属重组酶的活性部位与组氨酸的相互作用
12.Study of Interaction between Optical Probe and Copper, Zinc Containing Superoxide Dismutase, Amine and Its Application;光学探针与铜锌超氧化物歧化酶、胺类小分子相互作用的研究及应用
13.The Effect of Ambroxol on the Expression of AP-1 and CuZn-SOD in Lung of Smoking Rats;盐酸氨溴索对吸烟大鼠肺组织激活蛋白-1、铜锌超氧化物歧化酶表达的影响
14.Construction and expression of red fluorescent protein reporter gene vector for human SOD1人铜锌超氧化物歧化酶基因启动子驱动的红色荧光蛋白报告基因载体的构建及表达
15.DNA Cleavage Mediated by Copper-Containing, Zinc-Deficient Forms of Copper Zinc Superoxide Dismutase;缺锌含铜超氧化物歧化酶水解DNA作用研究
16.Superoxide Biosensor Based on Superoxide Dismutase/Nano-ZnO基于超氧化物歧化酶/氧化锌的超氧离子传感器
17.The Study on Effect of Qianlietaixinyin on Zn、Cu and SOD Levels in Prostate Gland;前列泰欣饮对前列腺锌、铜和超氧化物歧化酶水平的影响研究
18.Both DNA and Protein Oxidative Damage Mediated by the Zinc-depleted and Normal Superoxide Dismutase;正常及缺锌超氧化物歧化酶对DNA及蛋白质的氧化作用
相关短句/例句
CuZnSOD铜锌超氧化物歧化酶
1.Study on Interaction Between Coper Ion and Hog Liver CuZnSOD by Spectroscopy;Cu~(2+)和铜锌超氧化物歧化酶作用的光谱学研究
2.Separation,Purification and Physical-chemical Properties of CuZnSOD from Pig Liver;猪肝铜锌超氧化物歧化酶的分离纯化与理化性质研究
3.The crude enzyme solution of CuZnSOD from tobacco was obtained by using ammonium sulˉphate to form different levels of precipitates;chloroform and alcohol to isolate the impurities and acetone to further clean-up.利用硫酸铵盐析分级分离、乙醇 -氯仿沉淀除杂、丙酮再沉淀分级得到含铜锌超氧化物歧化酶(CuZnSOD)的粗酶液 ,通过DEAE_52离子交换层析实现了3种CuZnSOD同工酶的拆分 ;进一步通过G_75凝胶层析对3种同工酶分离纯化得到2种电泳纯产品CuZnSODⅠ和CuZnSODⅢ ;SDS-PAGE实验发现CuZnSODⅠ由两个不等亚基组成 ,亚基相对分子质量分别为15050、20950;CuZnSODⅢ存在一种亚基 ,亚基相对分子质量为22950 ;实验检测到2种纯酶分子含有不等量的Cu和Zn,酶学特性实验也证实了2种蛋白酶都是CuZnSOD。
3)Cu/Zn superoxide dismutase铜锌超氧化物歧化酶
1.Mutation Site of Cu/Zn superoxide dismutase in an amyotrophic lateral sclerosis family;肌萎缩侧索硬化症家系铜锌超氧化物歧化酶基因突变位点的检测
4)Cu-Zn superoxide dismutase铜-锌超氧化物歧化酶
5)copper and zinc superoxide dismutase铜锌超氧化物歧化酶
1.Purification and characterization of copper and zinc superoxide dismutase from sheep erythrocyte;羊红细胞铜锌超氧化物歧化酶的纯化及部分性质研究
6)human Cu/Zn-SOD人铜锌超氧化物歧化酶
1.Constraction of eukaryotic expression vector of human Cu/Zn-SOD and secretive expression in S.cerevisiae;人铜锌超氧化物歧化酶真核表达载体的构建及在酿酒酵母中的分泌表达
延伸阅读
铜铁锌氧化物CAS：54427-17-7中文名称：铜铁锌氧化物英文名称：Copper iron zinc oxide
