6β-羟基氢化可的松,6β-hydroxycortisol
1)6β-hydroxycortisol6β-羟基氢化可的松
1.Objective: To investigate the activity of CYP3A enzyme, an effective method of HPLC (Gradient elution)for determining the concentration of 6p-hydroxycortisol and cortisol in urine and measuring the ratio of 6β-hydroxycortisol and cortisol was established.目的:用HPLC法(梯度洗脱)测定尿液中6β-羟基氢化可的松(6β-OHC)和氢化可的松(HC)的含量,计算6β-OHC和HC的比值以反映人体中CYP3A酶的活性,为其研究提供有效的分析手段。
2.METHODS After collecting urine for 24 hours,the urinary concentrations of HC and 6β-hydroxycortisol(6β-OHC) were determined by high performance liquid chromatography(HPLC).方法:收集24h尿液,以HPLC法测定尿液中氢化可的松(HC)与6β-羟基氢化可的松(6β-OHC)的含量,以6β-OHC/HC来评估细胞色素P4503A酶的活性。
3.The endogenous 6β-hydroxycortisol and cortisol concentrations in the urine were determined.方法直接收集20例精神病住院患者晨尿液,测定尿液中内源性氢化可的松与6β-羟基氢化可的松的含量,以6β-羟基氢化可的松/氢化可的松来评估CYP3A酶的活性。
2)6β-OHE6β-羟基可的松
3)Hydrocortisone[英][,haidr?'k?:tis?un][美][,ha?dr?'k?rt?son]氢化可的松
1.Control Hydrocortisone Fermentation Process by Polarimetry;旋光法用于氢化可的松生产过程的控制
2.Bioconversion of compound S into hydrocortisone using a novel process of twi-run sequence bioconversion by the mycelium of Curvularia lunata AS 3.4381;静息细胞连续两批次生物催化生产氢化可的松
3.The Improvement of Stereoselectivity of Hydrocortisone Transformation;提高氢化可的松发酵过程中的微生物转化效率的初探
英文短句/例句

1.Compositions of cortisone and cortisol in colostrum of Holstein Cows牛初乳中可的松和氢化可的松质量分数变化
2.The Effects of Pressure on Synthesis of Hydrocortisone by Absidia Coeralea;压力对梨头霉合成氢化可的松的影响
3.Colon specific delivery study on hydrocortisone bilayer-coated tablets氢化可的松双层包衣片的结肠定位性
4.cortisol, not put up as medicaments氢化可的松,未配制成药物
5.OBJECTIVE To establish HPLC method for determination of chloramphenicol and hydrocortisone in ear drops.目的建立高效液相色谱法测定氯霉素氢化可的松滴耳液中氯霉素和氢化可的松的含量。
6.The relationship between hypokaliemia in Cushing syndrome and cortisol库欣综合征低钾血症与氢化可的松的关系探讨
7.Study on Bacterially Triggered Colon-Specific Preperation of Hydrocortisone;氢化可的松菌群触发型结肠靶向制剂的研究
8.Prediction of Solubilities of Hydrocortisone in Various Solvents via Artificial Neural Network应用人工神经网络预测氢化可的松的溶解度
9.Quantitative Determination of Hydrocortisone Injection by HPLC高效液相色谱法测定氢化可的松注射液的含量
10.Effects of hydrocortisone on the cytotoxicity and apoptosis of NK-92MI cells氢化可的松对NK-92MI细胞杀伤活性及凋亡的影响
11.Study on the CYP3A Phenotyping in Human by Endogenous Cortisol Metabolism;内源性氢化可的松代谢评价体内CYP3A活性研究
12.The Study of Hydrocortisone Fermentation by Curvularia Lunata;新月弯孢霉生物转化生产氢化可的松新工艺的研究
13.Objective: To explore the relationship between the occurrence of hypokaliemia in patients with Cushing syndrome and cortisol.目的 :探讨库欣综合征患者低钾血症的发生与氢化可的松的关系。
14.Objective To study the relationship between the occurrence of hypokalemia and hydrocortisone in patients with Cushing syndrome.①目的 探讨库欣综合征病人低钾血症的发生与氢化可的松的关系。
15.Objective: To establish a HPLC method for concurrent determination of chloramphenicol and hydrocortisone in chloramphenicol and hydrocortisone ear drops.目的:建立氯霉素氢化可的松滴耳液的含量测定方法。
16.Protective effects of Cordyceps militaris on hydrocortisone-induced renal injury in aging mice北冬虫夏草对氢化可的松诱导的老龄小鼠肾损伤的保护作用
17.RELATIONSHIP BETWEEN HYPOKALEMIA AND HYDROCORTISONE IN CUSHING SYNDROME库欣综合征低钾血症发生与氢化可的松关系的探讨
18.Effects of Hydrocortisone on the Synthesis of Melanin in A375 Human Melanoma Cells.;氢化可的松对人A375黑素瘤细胞株黑素合成的影响
相关短句/例句

6β-OHE6β-羟基可的松
3)Hydrocortisone[英][,haidr?'k?:tis?un][美][,ha?dr?'k?rt?son]氢化可的松
1.Control Hydrocortisone Fermentation Process by Polarimetry;旋光法用于氢化可的松生产过程的控制
2.Bioconversion of compound S into hydrocortisone using a novel process of twi-run sequence bioconversion by the mycelium of Curvularia lunata AS 3.4381;静息细胞连续两批次生物催化生产氢化可的松
3.The Improvement of Stereoselectivity of Hydrocortisone Transformation;提高氢化可的松发酵过程中的微生物转化效率的初探
4)Cortisol[英]['k?:tis?l][美]['k?rt?sɑl]氢化可的松
1.Simultaneous Determination the Contents of Cortisol and Cortisone in Serum by HPLC;RP-HPLC法同时测定人血清中内源性氢化可的松与可的松的含量
2.Simultaneous Determination of Endogenous Cortisol and Its Metabolite in Urine by HPLC-DAD;高效液相色谱-二极管阵列法同时检测尿中内源性氢化可的松及其代谢产物
3.Determination of CYP3A activity in vivo by the ratio of urinary endogenous 6β-hydroxycortisol to cortisol;内源性氢化可的松为探针的体内CYP3A活性测定
5)6β-hydroxylation6β-羟基化代谢率
1.RESULTS:In the study on correlation between F and E 6β-hydroxylation metabolism and the C/D ratio of CsA in renal transplant recipients,there were inverse correlations between 6β-OHF+6β-OHE/F+E and the C/D ratio of CsA,6β-OHF +6β-OHE/F+E and weight-normalized C/D ratio of CsA in all, male and female subjects.目的:研究肾移植患者尿中氢化可的松(F)及可的松(E)6β-羟基化代谢率与环孢霉素(CsA)血药浓度剂量比的相关性。
6)6-methlhydrocortisone6-甲基氢化可的松
1.Study on biotransformation of 6-methlhydrocortisone in aqueous two-phase systems;双水相体系中甾类化合物6-甲基氢化可的松的生物转化研究
延伸阅读

11-表氢化可的松分子式:C21H30O5分子量:362.47CAS号:566-35-8性质:结晶化合物。熔点217-220℃(部分分解)。溶于乙醇、甲醇、丙酮,略溶于氯仿,微溶于水、乙醚。制备方法:暂无用途:可的松醋酸酯、确炎舒松A醋酸酯、肤轻松醋酸酯的中间体。